DE69204995D1 - Isoindole mit cardiovaskulärer aktivität. - Google Patents

Isoindole mit cardiovaskulärer aktivität.

Info

Publication number
DE69204995D1
DE69204995D1 DE69204995T DE69204995T DE69204995D1 DE 69204995 D1 DE69204995 D1 DE 69204995D1 DE 69204995 T DE69204995 T DE 69204995T DE 69204995 T DE69204995 T DE 69204995T DE 69204995 D1 DE69204995 D1 DE 69204995D1
Authority
DE
Germany
Prior art keywords
alkoxy
hydroxy
halogen
alkyl
isoindole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69204995T
Other languages
English (en)
Other versions
DE69204995T2 (de
Inventor
Alberto Sala
Silvio Levi
Francesca Benedini
Roberta Cereda
Soldato Piero Del
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Italfarmaco SpA
Original Assignee
Italfarmaco SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco SpA filed Critical Italfarmaco SpA
Application granted granted Critical
Publication of DE69204995D1 publication Critical patent/DE69204995D1/de
Publication of DE69204995T2 publication Critical patent/DE69204995T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69204995T 1991-03-19 1992-03-11 Isoindole mit cardiovaskulärer aktivität. Expired - Fee Related DE69204995T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI910732A IT1245351B (it) 1991-03-19 1991-03-19 Isoindoli ad attivita' cardiovascolare
PCT/EP1992/000531 WO1992016506A1 (en) 1991-03-19 1992-03-11 Isoindoles having cardiovascular activity

Publications (2)

Publication Number Publication Date
DE69204995D1 true DE69204995D1 (de) 1995-10-26
DE69204995T2 DE69204995T2 (de) 1996-02-08

Family

ID=11359118

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69204995T Expired - Fee Related DE69204995T2 (de) 1991-03-19 1992-03-11 Isoindole mit cardiovaskulärer aktivität.

Country Status (13)

Country Link
US (1) US5376673A (de)
EP (1) EP0576475B1 (de)
JP (1) JPH06505722A (de)
AT (1) ATE128123T1 (de)
AU (1) AU659442B2 (de)
CA (1) CA2105684A1 (de)
DE (1) DE69204995T2 (de)
DK (1) DK0576475T3 (de)
ES (1) ES2079185T3 (de)
GR (1) GR3017990T3 (de)
HU (1) HUT67668A (de)
IT (1) IT1245351B (de)
WO (1) WO1992016506A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE172183T1 (de) * 1992-07-30 1998-10-15 Cal Int Ltd Ester und kombinationen von einem organischen nitrat und einem salicyclat

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6137766A (ja) * 1984-07-31 1986-02-22 Sankyo Co Ltd フタルイミド誘導体およびその製造法
DE3533442A1 (de) * 1985-09-19 1987-03-26 Hoechst Ag Neue 2-aryl-4,5,6,7-tetrahydroisoindolinone, verfahren zu ihrer herstellung sowie ihre verwendung im pflanzenschutz
IT1244472B (it) * 1990-12-14 1994-07-15 Italfarmaco Spa Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare

Also Published As

Publication number Publication date
AU659442B2 (en) 1995-05-18
ATE128123T1 (de) 1995-10-15
GR3017990T3 (en) 1996-02-29
ES2079185T3 (es) 1996-01-01
HUT67668A (en) 1995-04-28
EP0576475B1 (de) 1995-09-20
JPH06505722A (ja) 1994-06-30
ITMI910732A0 (it) 1991-03-19
HU9302507D0 (en) 1993-12-28
DK0576475T3 (da) 1996-01-15
ITMI910732A1 (it) 1992-09-19
DE69204995T2 (de) 1996-02-08
AU1347992A (en) 1992-10-21
WO1992016506A1 (en) 1992-10-01
CA2105684A1 (en) 1992-09-20
US5376673A (en) 1994-12-27
IT1245351B (it) 1994-09-20
EP0576475A1 (de) 1994-01-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee