DK0457318T3 - Alfa-Oxopyrrolo(2,3-b)indoleddikkesyrer, estere, salte og beslægtede analoge, en fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler - Google Patents

Alfa-Oxopyrrolo(2,3-b)indoleddikkesyrer, estere, salte og beslægtede analoge, en fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler

Info

Publication number
DK0457318T3
DK0457318T3 DK91107942.4T DK91107942T DK0457318T3 DK 0457318 T3 DK0457318 T3 DK 0457318T3 DK 91107942 T DK91107942 T DK 91107942T DK 0457318 T3 DK0457318 T3 DK 0457318T3
Authority
DK
Denmark
Prior art keywords
oxopyrrolo
pharmaceuticals
alpha
esters
salts
Prior art date
Application number
DK91107942.4T
Other languages
Danish (da)
English (en)
Inventor
Denise M Flanagan
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of DK0457318T3 publication Critical patent/DK0457318T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
DK91107942.4T 1990-05-17 1991-05-16 Alfa-Oxopyrrolo(2,3-b)indoleddikkesyrer, estere, salte og beslægtede analoge, en fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler DK0457318T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52462790A 1990-05-17 1990-05-17

Publications (1)

Publication Number Publication Date
DK0457318T3 true DK0457318T3 (da) 1996-12-09

Family

ID=24090019

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91107942.4T DK0457318T3 (da) 1990-05-17 1991-05-16 Alfa-Oxopyrrolo(2,3-b)indoleddikkesyrer, estere, salte og beslægtede analoge, en fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler

Country Status (22)

Country Link
EP (1) EP0457318B1 (de)
JP (1) JPH0826024B2 (de)
KR (2) KR100215615B1 (de)
AR (1) AR247888A1 (de)
AT (1) ATE141273T1 (de)
AU (1) AU634380B2 (de)
CA (1) CA2042737A1 (de)
CZ (1) CZ280922B6 (de)
DE (1) DE69121299T2 (de)
DK (1) DK0457318T3 (de)
ES (1) ES2094768T3 (de)
FI (1) FI96689C (de)
GR (1) GR3021043T3 (de)
HU (1) HU210179B (de)
IE (1) IE76318B1 (de)
IL (1) IL98162A (de)
MX (2) MX25777A (de)
NO (1) NO177710C (de)
NZ (2) NZ238151A (de)
PL (1) PL290273A1 (de)
PT (1) PT97688B (de)
ZA (1) ZA913711B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983616A (en) * 1990-02-01 1991-01-08 Hoechst-Roussel Pharmaceuticals Inc. Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds
AU634654B2 (en) * 1990-05-11 1993-02-25 Hoechst-Roussel Pharmaceuticals Incorporated Pyrrolo(2,3-b)indole-ketones and analogs, a process for their preparation and their use as medicaments
ES2113859T3 (es) * 1990-06-27 1998-05-16 Hoechst Marion Roussel Inc Tetrahidroisoquinolinilcarbamatos de 1,2,3,3a,8,8a-hexahidro-1,3a,8-trimetilpirrolo(2,3-b)indol.
US7229986B2 (en) 2000-05-16 2007-06-12 Takeda Pharmaceutical Company Ltd. Melanin-concentrating hormone antagonist
CN102203097B (zh) 2008-09-03 2015-08-26 新加坡南洋理工大学 三环手性化合物及其在不对称催化中的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline

Also Published As

Publication number Publication date
NZ260210A (en) 1996-02-27
AU7618291A (en) 1991-11-21
IE911678A1 (en) 1991-11-20
NO911892L (no) 1991-11-18
KR100215615B1 (ko) 1999-08-16
CA2042737A1 (en) 1991-11-18
NZ238151A (de) 1996-02-27
MX25777A (es) 1993-10-01
FI912363A (fi) 1991-11-18
HU210179B (en) 1995-02-28
JPH04226989A (ja) 1992-08-17
NO911892D0 (no) 1991-05-15
HUT61310A (en) 1992-12-28
DE69121299D1 (de) 1996-09-19
FI96689C (fi) 1996-08-12
CS142991A3 (en) 1992-01-15
NO177710C (no) 1995-11-08
JPH0826024B2 (ja) 1996-03-13
PT97688B (pt) 1998-08-31
CZ280922B6 (cs) 1996-05-15
ATE141273T1 (de) 1996-08-15
FI96689B (fi) 1996-04-30
NO177710B (no) 1995-07-31
ES2094768T3 (es) 1997-02-01
FI912363A0 (fi) 1991-05-15
KR910020014A (ko) 1991-12-19
IE76318B1 (en) 1997-10-22
MX25816A (es) 1993-11-01
IL98162A (en) 1994-12-29
KR100227715B1 (ko) 2000-03-15
GR3021043T3 (en) 1996-12-31
EP0457318A1 (de) 1991-11-21
PT97688A (pt) 1992-02-28
DE69121299T2 (de) 1997-02-06
PL290273A1 (en) 1992-07-27
AR247888A1 (es) 1995-04-28
HU911658D0 (en) 1991-11-28
EP0457318B1 (de) 1996-08-14
IL98162A0 (en) 1992-06-21
ZA913711B (en) 1992-01-29
AU634380B2 (en) 1993-02-18

Similar Documents

Publication Publication Date Title
FI894637A0 (fi) Menetelmä mikroemulsion käsittävän farmaseuttisen formulaation valmistamiseksi
IS1895B (is) Hliðstæðuaðferð til framleiðslu á cytidine-afleiðum
AU2301988A (en) Process for preparing sulfonylurea salts
DK349387A (da) Nitrofuranderivater samt fremgangsmaade til fremstilling deraf og anvendelse af forbindelserne som laegemiddel
DE69224420D1 (de) Verfahren zum Speisen von Leistung in ein ophthalmisches Gaslasersystem
NO900740L (no) Fremgangsmaate for syntetisering av tris-hydroxymethyl-alkanestere som fettimitasjoner med lavt kaloriinnhold.
DK0457318T3 (da) Alfa-Oxopyrrolo(2,3-b)indoleddikkesyrer, estere, salte og beslægtede analoge, en fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler
EP0328824A3 (en) Sulfonic acid esters useful as sensitizers for positive resists
NO173497C (no) 2-aza-4-(alkoksykarbonyl)spiro(4,5)-dekan-3-on, en fremgangsmaate ved fremstilling derav, og (1-cyanocyklo-heksyl)-malonsyredialkylester som mellomprodukt i fremgangsmaaten
NO912545L (no) Nye 3,3'-ditiobis(propionsyrer) og estere derav samt fremgangsmaate for deres fremstilling
FI895982A0 (fi) Menetelmä lääkeaineina käyttökelpoisten 2-imino-6-polyfluorialkoksibentsotiatsolijohdannaisten valmistamiseksi
EP0357787A4 (en) Process for preparing optically active 2-hydroxy acid derivatives
NO891984D0 (no) Fremgangsmaate for fremstilling av 1,4-dikydro-4-okso-kinolin-3-karboksylsyreestere.
NO944680D0 (no) Nye tienotiazinerivater, en fremgangsmåte til fremstilling derav samt deres anvendelse
FI101600B1 (fi) Menetelmä farmaseuttisen formulaation valmistamiseksi
NO884110L (no) Nye aminosyreestere samt fremgangsmaaten for fremstilling derav.
EP0375417A3 (en) Process for preparing optically active carnitine ester
DK231089D0 (da) Substituerede azolthioethere, fremgangsmaade til fremstilling deraf samt deres anvendelse som skadedyrsbekaempelsesmiddel
FI93216C (fi) Analogiamenetelmä terapeuttisesti käyttökelpoisten 1,3-dioksaanialkeenihappojohdannaisten valmistamiseksi
DK0790245T3 (da) Substituerede thiophenylalkenylcarboxylsyreguanidider, fremgangsmåde til deres fremstilling, deres anvendelse som lægemiddel eller diagnostikum samt lægemiddel med indhold deraf
DK547289D0 (da) Benzoisothiazoler og fremgangsmaade til fremstilling deraf samt deres anvendelse som skadedyrsbekaempelsesmiddel
DK247184D0 (da) Optisk aktive propionsyre-ester-derivater,fremgangsmaader til deres fremstilling samt deres anvendelse som herbicider
IL90333A0 (en) Process for the racemization of optically active d-2-n-phenacetyl-amino-4-methyl-phosphinobutyric acid
ZA894386B (en) Process for the preparation of n-(23-vinblastinoyl)derivatives of 1-amino methylphosphonic acid
NO885185D0 (no) FremgangsmŸte til fremstilling av alkanolaminderivater.