PT97688A - Processo para a preparacao de amidas, esteres, acidos alfa-oxo-pirrolo{2,3-b}indol-acetico e analogos relacionados e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de amidas, esteres, acidos alfa-oxo-pirrolo{2,3-b}indol-acetico e analogos relacionados e de composicoes farmaceuticas que os contem

Info

Publication number
PT97688A
PT97688A PT97688A PT9768891A PT97688A PT 97688 A PT97688 A PT 97688A PT 97688 A PT97688 A PT 97688A PT 9768891 A PT9768891 A PT 9768891A PT 97688 A PT97688 A PT 97688A
Authority
PT
Portugal
Prior art keywords
indol
pyrrole
oxo
alpha
esters
Prior art date
Application number
PT97688A
Other languages
English (en)
Other versions
PT97688B (pt
Inventor
Denise M Flanagen
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of PT97688A publication Critical patent/PT97688A/pt
Publication of PT97688B publication Critical patent/PT97688B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Indole Compounds (AREA)
PT97688A 1990-05-17 1991-05-16 Processo para a preparacao de amidas, esteres, acidos alfa-oxo-pirrolo{2,3-b}indol-acetico e analogos relacionados e de composicoes farmaceuticas que os contem PT97688B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52462790A 1990-05-17 1990-05-17

Publications (2)

Publication Number Publication Date
PT97688A true PT97688A (pt) 1992-02-28
PT97688B PT97688B (pt) 1998-08-31

Family

ID=24090019

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97688A PT97688B (pt) 1990-05-17 1991-05-16 Processo para a preparacao de amidas, esteres, acidos alfa-oxo-pirrolo{2,3-b}indol-acetico e analogos relacionados e de composicoes farmaceuticas que os contem

Country Status (22)

Country Link
EP (1) EP0457318B1 (pt)
JP (1) JPH0826024B2 (pt)
KR (2) KR100215615B1 (pt)
AR (1) AR247888A1 (pt)
AT (1) ATE141273T1 (pt)
AU (1) AU634380B2 (pt)
CA (1) CA2042737A1 (pt)
CZ (1) CZ280922B6 (pt)
DE (1) DE69121299T2 (pt)
DK (1) DK0457318T3 (pt)
ES (1) ES2094768T3 (pt)
FI (1) FI96689C (pt)
GR (1) GR3021043T3 (pt)
HU (1) HU210179B (pt)
IE (1) IE76318B1 (pt)
IL (1) IL98162A (pt)
MX (2) MX25777A (pt)
NO (1) NO177710C (pt)
NZ (2) NZ260210A (pt)
PL (1) PL290273A1 (pt)
PT (1) PT97688B (pt)
ZA (1) ZA913711B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983616A (en) * 1990-02-01 1991-01-08 Hoechst-Roussel Pharmaceuticals Inc. Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds
AU634654B2 (en) * 1990-05-11 1993-02-25 Hoechst-Roussel Pharmaceuticals Incorporated Pyrrolo(2,3-b)indole-ketones and analogs, a process for their preparation and their use as medicaments
ES2113859T3 (es) * 1990-06-27 1998-05-16 Hoechst Marion Roussel Inc Tetrahidroisoquinolinilcarbamatos de 1,2,3,3a,8,8a-hexahidro-1,3a,8-trimetilpirrolo(2,3-b)indol.
WO2001087834A1 (fr) * 2000-05-16 2001-11-22 Takeda Chemical Industries, Ltd. Antagoniste de l'hormone de concentration de la melanine
US9206090B2 (en) 2008-09-03 2015-12-08 Nanyang Technological University Tricyclic chiral compounds and their use in asymmetric catalysis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline

Also Published As

Publication number Publication date
NO177710C (no) 1995-11-08
JPH0826024B2 (ja) 1996-03-13
DK0457318T3 (da) 1996-12-09
NO177710B (no) 1995-07-31
DE69121299T2 (de) 1997-02-06
CA2042737A1 (en) 1991-11-18
FI912363A0 (fi) 1991-05-15
GR3021043T3 (en) 1996-12-31
NZ238151A (pt) 1996-02-27
FI912363A (fi) 1991-11-18
AU634380B2 (en) 1993-02-18
ZA913711B (en) 1992-01-29
PT97688B (pt) 1998-08-31
IL98162A0 (en) 1992-06-21
NZ260210A (en) 1996-02-27
NO911892L (no) 1991-11-18
KR910020014A (ko) 1991-12-19
IE911678A1 (en) 1991-11-20
FI96689B (fi) 1996-04-30
IL98162A (en) 1994-12-29
EP0457318B1 (en) 1996-08-14
FI96689C (fi) 1996-08-12
NO911892D0 (no) 1991-05-15
MX25816A (es) 1993-11-01
MX25777A (es) 1993-10-01
HU210179B (en) 1995-02-28
IE76318B1 (en) 1997-10-22
AR247888A1 (es) 1995-04-28
CS142991A3 (en) 1992-01-15
KR100227715B1 (ko) 2000-03-15
HU911658D0 (en) 1991-11-28
KR100215615B1 (ko) 1999-08-16
ATE141273T1 (de) 1996-08-15
AU7618291A (en) 1991-11-21
HUT61310A (en) 1992-12-28
EP0457318A1 (en) 1991-11-21
JPH04226989A (ja) 1992-08-17
DE69121299D1 (de) 1996-09-19
CZ280922B6 (cs) 1996-05-15
ES2094768T3 (es) 1997-02-01
PL290273A1 (en) 1992-07-27

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19911028

FG3A Patent granted, date of granting

Effective date: 19980525

MM3A Annulment or lapse

Effective date: 20041125