DE962637C - Verfahren zur Herstellung von kristallinem Insulin - Google Patents

Verfahren zur Herstellung von kristallinem Insulin

Info

Publication number
DE962637C
DE962637C DEN7344A DEN0007344A DE962637C DE 962637 C DE962637 C DE 962637C DE N7344 A DEN7344 A DE N7344A DE N0007344 A DEN0007344 A DE N0007344A DE 962637 C DE962637 C DE 962637C
Authority
DE
Germany
Prior art keywords
production
crystalline insulin
insulin
crystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEN7344A
Other languages
English (en)
Inventor
Karl Petersen
Jorgen Schlichtkrull
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NOVO TERAPEUTISK LABOR AS
Original Assignee
NOVO TERAPEUTISK LABOR AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DK528252A priority Critical patent/DK78069C/da
Application filed by NOVO TERAPEUTISK LABOR AS filed Critical NOVO TERAPEUTISK LABOR AS
Application granted granted Critical
Publication of DE962637C publication Critical patent/DE962637C/de
Expired legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D9/00Crystallisation
    • B01D9/005Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • C07K14/625Extraction from natural sources
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
DEN7344A 1952-06-23 1953-06-18 Verfahren zur Herstellung von kristallinem Insulin Expired DE962637C (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK528252A DK78069C (da) 1952-06-23 1952-06-23 Fremgangsmåde til fremstilling af krystallinsk insulin.

Publications (1)

Publication Number Publication Date
DE962637C true DE962637C (de) 1957-04-25

Family

ID=8141106

Family Applications (1)

Application Number Title Priority Date Filing Date
DEN7344A Expired DE962637C (de) 1952-06-23 1953-06-18 Verfahren zur Herstellung von kristallinem Insulin

Country Status (6)

Country Link
US (1) US2920014A (de)
CY (1) CY161A (de)
DE (1) DE962637C (de)
DK (1) DK78069C (de)
FR (1) FR1167005A (de)
GB (1) GB733740A (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DE3327928A1 (de) * 1983-08-03 1985-02-21 Hoechst Ag Verfahren zur herstellung von insulin-derivaten
US4764592A (en) * 1987-04-23 1988-08-16 Eli Lilly And Company Crystalline human proinsulin and process for its production
US5504188A (en) * 1994-06-16 1996-04-02 Eli Lilly And Company Preparation of stable zinc insulin analog crystals
US5597893A (en) * 1994-10-31 1997-01-28 Eli Lilly And Company Preparation of stable insulin analog crystals
AR002976A1 (es) * 1995-03-31 1998-05-27 Lilly Co Eli Formulaciones farmaceuticas parenterales de efecto prolongado de insulina; cristales de dichos analogos aplicables en dichas formulaciones yprocedimiento de las formulaciones mencionadas
KR19990071255A (ko) 1998-02-28 1999-09-15 성재갑 소마토트로핀과 비타민의 합제 조성물
KR101309770B1 (ko) * 2004-07-19 2013-09-30 바이오콘 리미티드 인슐린―올리고머 접합체,제형 및 이들의 용도
MX2010003979A (es) * 2007-10-16 2010-06-02 Biocon Ltd ORMALLY ADMINISTRABLE PHARMACEUTICAL COMPOSITION AND PROCESS FOR PREPARATION.
GB201409451D0 (en) 2014-05-28 2014-07-09 Ipabc Ltd Antimicrobial preparations, methods for preparing the same and uses thereof to combat microorganisms
US10124040B2 (en) 2014-08-26 2018-11-13 Merck Sharp & Dohme Corp. Method for preparing crystalline insulin or insulin analog compositions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE835499C (de) * 1945-05-17 1952-03-31 Novo Terapeutisk Labor As Verfahren zur Herstellung von Inselhormon in kristallinischer Form

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2143590A (en) * 1936-09-26 1939-01-10 Univ Alberta Insulin preparation and process of producing crystals of insulin
US2143591A (en) * 1936-09-26 1939-01-10 Univ Alberta Therapeutic preparation and process of making and using it
US2626228A (en) * 1945-05-17 1953-01-20 Novo Terapeutisk Labor As Method of producing crystalline insulin
US2779706A (en) * 1950-08-12 1957-01-29 Organon Insulin extraction
US2819999A (en) * 1953-11-13 1958-01-14 Novo Terapeutisk Labor As Process for crystallization of insulin using freeze dried insulin as seeding material
US2799622A (en) * 1953-11-14 1957-07-16 Novo Terapeutisk Labor As Process of producing insulin crystals of substantially uniform size and compositions thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE835499C (de) * 1945-05-17 1952-03-31 Novo Terapeutisk Labor As Verfahren zur Herstellung von Inselhormon in kristallinischer Form

Also Published As

Publication number Publication date
GB733740A (en) 1955-07-20
US2920014A (en) 1960-01-05
CY161A (en) 1957-06-26
DK78069C (da) 1954-09-06
FR1167005A (fr) 1958-11-19

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