DK78069C - Fremgangsmåde til fremstilling af krystallinsk insulin. - Google Patents

Fremgangsmåde til fremstilling af krystallinsk insulin.

Info

Publication number
DK78069C
DK78069C DK198252AA DK528252A DK78069C DK 78069 C DK78069 C DK 78069C DK 198252A A DK198252A A DK 198252AA DK 528252 A DK528252 A DK 528252A DK 78069 C DK78069 C DK 78069C
Authority
DK
Denmark
Prior art keywords
production
crystalline insulin
insulin
crystalline
Prior art date
Application number
DK198252AA
Other languages
Danish (da)
English (en)
Inventor
Karl Petersen
Joergen Schlichtkrull
Original Assignee
Novo Terapeutisk Labor As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Terapeutisk Labor As filed Critical Novo Terapeutisk Labor As
Priority to DK198252AA priority Critical patent/DK78069C/da
Priority to GB16635/53A priority patent/GB733740A/en
Priority to DEN7344A priority patent/DE962637C/de
Priority to FR1167005D priority patent/FR1167005A/fr
Application granted granted Critical
Publication of DK78069C publication Critical patent/DK78069C/da
Priority to CY16157A priority patent/CY161A/xx
Priority to US692612A priority patent/US2920014A/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C07K14/625—Extraction from natural sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK198252AA 1952-06-23 1952-06-23 Fremgangsmåde til fremstilling af krystallinsk insulin. DK78069C (da)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DK198252AA DK78069C (da) 1952-06-23 1952-06-23 Fremgangsmåde til fremstilling af krystallinsk insulin.
GB16635/53A GB733740A (en) 1952-06-23 1953-06-16 Improvements in or relating to a process for the production of crystalline insulin
DEN7344A DE962637C (de) 1952-06-23 1953-06-18 Verfahren zur Herstellung von kristallinem Insulin
FR1167005D FR1167005A (fr) 1952-06-23 1953-06-19 Perfectionnements apportés aux procédés pour la production d'insuline cristallisée
CY16157A CY161A (en) 1952-06-23 1957-06-26 Improvements in or relating to a process for the production of crystalline insulin
US692612A US2920014A (en) 1952-06-23 1957-10-28 Insulin crystals and preparations and processes for producing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK198252AA DK78069C (da) 1952-06-23 1952-06-23 Fremgangsmåde til fremstilling af krystallinsk insulin.

Publications (1)

Publication Number Publication Date
DK78069C true DK78069C (da) 1954-09-06

Family

ID=8141106

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198252AA DK78069C (da) 1952-06-23 1952-06-23 Fremgangsmåde til fremstilling af krystallinsk insulin.

Country Status (6)

Country Link
US (1) US2920014A (de)
CY (1) CY161A (de)
DE (1) DE962637C (de)
DK (1) DK78069C (de)
FR (1) FR1167005A (de)
GB (1) GB733740A (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DE3327928A1 (de) * 1983-08-03 1985-02-21 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten
US4764592A (en) * 1987-04-23 1988-08-16 Eli Lilly And Company Crystalline human proinsulin and process for its production
US5504188A (en) * 1994-06-16 1996-04-02 Eli Lilly And Company Preparation of stable zinc insulin analog crystals
US5597893A (en) * 1994-10-31 1997-01-28 Eli Lilly And Company Preparation of stable insulin analog crystals
YU18596A (sh) * 1995-03-31 1998-07-10 Eli Lilly And Company Analogne formulacije monomernog insulina
KR19990071255A (ko) 1998-02-28 1999-09-15 성재갑 소마토트로핀과 비타민의 합제 조성물
AU2005269753B2 (en) * 2004-07-19 2011-08-18 Biocon Limited Insulin-oligomer conjugates, formulations and uses thereof
PT2203181T (pt) * 2007-10-16 2018-05-10 Biocon Ltd Uma composição farmacêutica sólida para administração por via oral e o seu processo de fabrico
GB201409451D0 (en) 2014-05-28 2014-07-09 Ipabc Ltd Antimicrobial preparations, methods for preparing the same and uses thereof to combat microorganisms
EP3185887B1 (de) 2014-08-26 2021-03-10 Merck Sharp & Dohme Corp. Verfahren zur herstellung von kristallinem insulin oder insulin-analog-zusammensetzungen
MX2020004042A (es) * 2017-09-26 2021-01-15 Biocon Biologics India Ltd Filtracion automatizada integrada para separacion, lavado y secado de cristales de peptidos.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2143590A (en) * 1936-09-26 1939-01-10 Univ Alberta Insulin preparation and process of producing crystals of insulin
US2143591A (en) * 1936-09-26 1939-01-10 Univ Alberta Therapeutic preparation and process of making and using it
DE835499C (de) * 1945-05-17 1952-03-31 Novo Terapeutisk Labor As Verfahren zur Herstellung von Inselhormon in kristallinischer Form
US2626228A (en) * 1945-05-17 1953-01-20 Novo Terapeutisk Labor As Method of producing crystalline insulin
US2779706A (en) * 1950-08-12 1957-01-29 Organon Insulin extraction
US2819999A (en) * 1953-11-13 1958-01-14 Novo Terapeutisk Labor As Process for crystallization of insulin using freeze dried insulin as seeding material
US2799622A (en) * 1953-11-14 1957-07-16 Novo Terapeutisk Labor As Process of producing insulin crystals of substantially uniform size and compositions thereof

Also Published As

Publication number Publication date
DE962637C (de) 1957-04-25
GB733740A (en) 1955-07-20
FR1167005A (fr) 1958-11-19
US2920014A (en) 1960-01-05
CY161A (en) 1957-06-26

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