DE69919575T2 - Benzoxazolderivate und medikamente die diese als aktiven wirkstoff enthalten - Google Patents

Benzoxazolderivate und medikamente die diese als aktiven wirkstoff enthalten Download PDF

Info

Publication number
DE69919575T2
DE69919575T2 DE69919575T DE69919575T DE69919575T2 DE 69919575 T2 DE69919575 T2 DE 69919575T2 DE 69919575 T DE69919575 T DE 69919575T DE 69919575 T DE69919575 T DE 69919575T DE 69919575 T2 DE69919575 T2 DE 69919575T2
Authority
DE
Germany
Prior art keywords
chloro
compound
mixture
solution
added
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69919575T
Other languages
German (de)
English (en)
Other versions
DE69919575D1 (de
Inventor
Sojiro Yokohama-shi SHIOKAWA
Yasuo Yokohama-shi Sato
Masaaki Yokohama-shi IZUMI
Satoshi Yokohama-shi YOSHIDA
Hiroshi Kawasaki-shi MURAKAMI
Tomoko Yokohama-shi ITO
Tetsutaro Yokohama-shi NIISATO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lotus Pharmaceutical Co Ltd
Original Assignee
Shudo Koichi Prof Drchem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shudo Koichi Prof Drchem filed Critical Shudo Koichi Prof Drchem
Publication of DE69919575D1 publication Critical patent/DE69919575D1/de
Application granted granted Critical
Publication of DE69919575T2 publication Critical patent/DE69919575T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE69919575T 1998-11-20 1999-11-19 Benzoxazolderivate und medikamente die diese als aktiven wirkstoff enthalten Expired - Lifetime DE69919575T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP33127498 1998-11-20
JP33127498 1998-11-20
PCT/JP1999/006491 WO2000031073A1 (fr) 1998-11-20 1999-11-19 Derives de benzoxazole et produits a base de ces derniers utilises comme ingredient actif

Publications (2)

Publication Number Publication Date
DE69919575D1 DE69919575D1 (de) 2004-09-23
DE69919575T2 true DE69919575T2 (de) 2005-09-29

Family

ID=18241866

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69919575T Expired - Lifetime DE69919575T2 (de) 1998-11-20 1999-11-19 Benzoxazolderivate und medikamente die diese als aktiven wirkstoff enthalten

Country Status (23)

Country Link
US (1) US7045516B1 (ja)
EP (1) EP1134220B1 (ja)
JP (1) JP4557112B2 (ja)
KR (1) KR100675033B1 (ja)
CN (1) CN1333771A (ja)
AT (1) ATE273974T1 (ja)
AU (1) AU753797B2 (ja)
BR (1) BR9916793A (ja)
CA (1) CA2351446A1 (ja)
CZ (1) CZ20011700A3 (ja)
DE (1) DE69919575T2 (ja)
ES (1) ES2222763T3 (ja)
HU (1) HUP0104238A3 (ja)
ID (1) ID30143A (ja)
IL (1) IL143178A0 (ja)
NO (1) NO20012443L (ja)
PL (1) PL348426A1 (ja)
RU (1) RU2204558C2 (ja)
SK (1) SK6772001A3 (ja)
TR (1) TR200101945T2 (ja)
TW (1) TW520370B (ja)
WO (1) WO2000031073A1 (ja)
ZA (1) ZA200104620B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6660858B2 (en) * 2001-03-28 2003-12-09 Lion Bioscience Ag 2-aminobenzoxazole derivatives and combinatorial libraries thereof
GB0203061D0 (en) * 2002-02-08 2002-03-27 Novartis Ag Organic compounds
JP4399862B2 (ja) * 2002-08-09 2010-01-20 味の素株式会社 腸疾患および内臓痛の治療薬
EP1906951A4 (en) * 2005-07-01 2009-05-27 Dynogen Pharmaceuticals Inc COMPOSITIONS AND METHODS FOR TREATING HYPOMOTILITY OF THE DIGESTIVE SYSTEM AND RELATED DISORDERS
WO2007110364A1 (en) 2006-03-28 2007-10-04 High Point Pharmaceuticals, Llc Benzothiazoles having histamine h3 receptor activity
US8178666B2 (en) * 2008-10-23 2012-05-15 Albany Molecular Research, Inc. 2-aminobenzoxazole process
KR101579688B1 (ko) 2014-07-08 2015-12-24 재단법인 전남생물산업진흥원 좁쌀풀 추출물을 유효성분으로 함유하는 과민성 대장증후군에 의한 내장 통증 억제예방 또는 치료용 약학 조성물
MX2022015770A (es) * 2020-06-12 2023-01-19 Hk Inno N Corp Composicion farmaceutica que comprende un compuesto derivado de benzimidazol.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3193560B2 (ja) * 1993-04-16 2001-07-30 明治製菓株式会社 新規ベンゾオキサゾール誘導体
JP3520177B2 (ja) * 1996-05-09 2004-04-19 明治製菓株式会社 セロトニン5−ht3受容体部分活性薬

Also Published As

Publication number Publication date
ES2222763T3 (es) 2005-02-01
ATE273974T1 (de) 2004-09-15
BR9916793A (pt) 2001-11-13
SK6772001A3 (en) 2001-12-03
ID30143A (id) 2001-11-08
RU2204558C2 (ru) 2003-05-20
WO2000031073A1 (fr) 2000-06-02
CA2351446A1 (en) 2000-06-02
EP1134220A4 (en) 2001-12-19
JP4557112B2 (ja) 2010-10-06
TR200101945T2 (tr) 2001-11-21
KR20010086448A (ko) 2001-09-12
HUP0104238A2 (en) 2002-08-28
EP1134220B1 (en) 2004-08-18
HUP0104238A3 (en) 2003-05-28
PL348426A1 (en) 2002-05-20
NO20012443L (no) 2001-07-12
CN1333771A (zh) 2002-01-30
US7045516B1 (en) 2006-05-16
KR100675033B1 (ko) 2007-01-29
TW520370B (en) 2003-02-11
NO20012443D0 (no) 2001-05-18
EP1134220A1 (en) 2001-09-19
IL143178A0 (en) 2002-04-21
DE69919575D1 (de) 2004-09-23
AU1185000A (en) 2000-06-13
ZA200104620B (en) 2002-02-04
AU753797B2 (en) 2002-10-31
CZ20011700A3 (cs) 2001-10-17

Similar Documents

Publication Publication Date Title
DE69407176T2 (de) Antipsychotische benzimidazolderivate
DE60030574T2 (de) Fünfgliedrige derivate von heterozyklen und ihre verwendung als monoaminoxidase-inhibitoren
DE69823648T2 (de) 1-phenyl-4-benzylpiperazine: spezifische liganden für den dopamin rezeptor (d4)
DE69518373T2 (de) Neue Zusammensetzungen, die Sertralin und einem 5-HT1D-Rezeptoragonisten oder Antagonisten enthalten
DE60218037T2 (de) Neue indolderivate mit affinität zum 5-ht6-rezeptor
DE3782525T2 (de) Aryl-substituierte(n-piperidinyl)methyl und (n-piperazinyl)methylazole mit antipsychotischer wirkung.
DE69014351T2 (de) Pyridincarbonsäureamid-Derivate und diese enthaltende pharmazeutische Zusammensetzungen.
DE69613240T2 (de) N-aminoalkylfluorencarboxamide, neue klasse von dopaminerezeptor subtype spezifische liganden
DE69804273T2 (de) 5h-Thiazolo[3,2-a]pyrimidinderivate
DE60305484T2 (de) Verbindungen und deren verwendung als 5-ht inhibitoren
DE69128231T2 (de) Heterozyklische Alkylamine, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen die sie enthalten
DE60022867T2 (de) 1-Arenesulfonyl-2-Aryl-Pyrrolidin und Piperidin Derivative zur Behandlung von CNS-Erkrankungen
DE3342164C2 (ja)
DE69733427T2 (de) Tetrahydrobezindol derivate
DE69919575T2 (de) Benzoxazolderivate und medikamente die diese als aktiven wirkstoff enthalten
DE2628189A1 (de) 3-phenylindoline, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP1176144B1 (de) Neue N-Triazolylmethyl-Piperazinderivate als Neurokininrezeptor-Antagonisten
DE69720317T2 (de) Benzoxazole Derivate als Serotonin 5-HT3 Rezeptor partiell Aktivator
DE69615404T2 (de) 2,7-SUBSTITUIERTE OCTAHYDROPYRROLO(1,2-a)PYRAZINDERIVATE
DE69232484T2 (de) Hydroisochinolinderivate
DE69612753T2 (de) (r)-5-bromo-n-(1-ethyl-4-methylhexahydro-1h-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridincarboxamid, verfahren zu seinerherstellung und dieses enthaltende medizinische zubereitung
DE68916198T2 (de) Carbamoyl-2-Pyrrolidinonverbindungen.
DE69228042T2 (de) Naphthamide, Verfahren zur Herstellung und ihre therapeutische Anwendung
DE60205397T2 (de) 4-(thio- oder selenoxanthen-9-yliden)-piperidin oder acridin derivate und ihre verwendung als selektive 5ht2b rezeptorantagonisten
EP0409048A2 (de) Aminoalkylsubstituierte 2-Aminothiazole und diese enthaltende therapeutische Mittel

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ORDER-MADE SOUYAKU CO., LTD., TOKYO, JP

8327 Change in the person/name/address of the patent owner

Owner name: LOTUS PHARMACEUTICALS CO., LTD., TOKYO, JP