DE69914493T2 - Verfahren zur herstellung von 2-hydroxy-6-trifluormethylpyridin - Google Patents

Verfahren zur herstellung von 2-hydroxy-6-trifluormethylpyridin Download PDF

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Publication number
DE69914493T2
DE69914493T2 DE69914493T DE69914493T DE69914493T2 DE 69914493 T2 DE69914493 T2 DE 69914493T2 DE 69914493 T DE69914493 T DE 69914493T DE 69914493 T DE69914493 T DE 69914493T DE 69914493 T2 DE69914493 T2 DE 69914493T2
Authority
DE
Germany
Prior art keywords
trifluoromethylpyridine
fluoro
hydroxy
chloro
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69914493T
Other languages
German (de)
English (en)
Other versions
DE69914493D1 (de
Inventor
Michael Erwin SEIDEL
Dale David FRIESE
Pai-Yung Alexander FUNG
Desmond John HUNT
Vincent Raymond Grangemouth JONES
John Alan Grangemouth WHITTON
Iain Alastair Grangemouth STEWART
Ann Jennifer Grangemouth WHITE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Corteva Agriscience LLC
Original Assignee
Syngenta Ltd
Dow AgroSciences LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Ltd, Dow AgroSciences LLC filed Critical Syngenta Ltd
Application granted granted Critical
Publication of DE69914493D1 publication Critical patent/DE69914493D1/de
Publication of DE69914493T2 publication Critical patent/DE69914493T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B41/00Formation or introduction of functional groups containing oxygen
    • C07B41/02Formation or introduction of functional groups containing oxygen of hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26Radicals substituted by halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69914493T 1998-09-03 1999-09-02 Verfahren zur herstellung von 2-hydroxy-6-trifluormethylpyridin Expired - Lifetime DE69914493T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9819235 1998-09-03
GBGB9819235.4A GB9819235D0 (en) 1998-09-03 1998-09-03 Chemical process
PCT/GB1999/002894 WO2000014068A1 (en) 1998-09-03 1999-09-02 Chemical process for preparing 2-hydroxy-6-trifluoromethylpyridine

Publications (2)

Publication Number Publication Date
DE69914493D1 DE69914493D1 (de) 2004-03-04
DE69914493T2 true DE69914493T2 (de) 2004-07-22

Family

ID=10838299

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69914493T Expired - Lifetime DE69914493T2 (de) 1998-09-03 1999-09-02 Verfahren zur herstellung von 2-hydroxy-6-trifluormethylpyridin

Country Status (14)

Country Link
US (1) US6143899A (OSRAM)
EP (1) EP1109788B1 (OSRAM)
JP (1) JP4302322B2 (OSRAM)
KR (1) KR100567197B1 (OSRAM)
CN (1) CN1134416C (OSRAM)
AT (1) ATE258547T1 (OSRAM)
AU (1) AU5638399A (OSRAM)
BR (1) BR9913401B1 (OSRAM)
DE (1) DE69914493T2 (OSRAM)
DK (1) DK1109788T3 (OSRAM)
ES (1) ES2215397T3 (OSRAM)
GB (1) GB9819235D0 (OSRAM)
IL (2) IL141597A0 (OSRAM)
WO (1) WO2000014068A1 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0016336D0 (en) 2000-07-03 2000-08-23 Zeneca Ltd Chemical process
GB0016338D0 (en) 2000-07-03 2000-08-23 Zeneca Ltd Chemical process
WO2015151116A2 (en) * 2014-03-31 2015-10-08 Jubilant Life Sciences Limited Process for producing 2-fluoro-6-(trifluoromethyl)pyridine compounds
CN107759513A (zh) * 2017-11-17 2018-03-06 山东汇盟生物科技有限公司 一种2‑羟基‑6‑三氟甲基吡啶的制备方法
CN108997203B (zh) * 2018-06-26 2020-08-14 江苏扬农化工集团有限公司 一种2,3-二氯-5-三氟甲基吡啶的高效提纯方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB288628A (en) * 1927-04-14 1929-07-03 Schering Kahlbaum Ag Process for the manufacture of hydroxypyridine compounds
US3355456A (en) * 1965-05-06 1967-11-28 Dow Chemical Co Production of monohalopyridinols
US3609158A (en) * 1969-03-17 1971-09-28 Dow Chemical Co Certain substituted (pyridyl)-oxy acetic acid derivatives
US3711486A (en) * 1969-03-17 1973-01-16 Dow Chemical Co Substituted(trifluoromethyl)pyridines
GB1303679A (OSRAM) * 1970-06-30 1973-01-17
US4108629A (en) * 1973-03-19 1978-08-22 The Dow Chemical Company Herbicidal use of esters of aminohalopyridyloxy acids
US4038396A (en) * 1975-02-24 1977-07-26 Merck & Co., Inc. Anti-inflammatory oxazole[4,5-b]pyridines
US4249009A (en) * 1979-01-29 1981-02-03 Reilly Tar & Chemical Corp. Processes for preparing 2-chloro-5-trifluoromethylpyridine
US4474599A (en) * 1982-07-14 1984-10-02 The Dow Chemical Company 1-(Pyridyl)-1H-1,2,3-triazole derivatives, and use as herbicidal agents
US4455313A (en) * 1982-08-20 1984-06-19 The Dow Chemical Company Fungicidal control employing substituted pyridinols
JPS6348268A (ja) * 1986-08-14 1988-02-29 Ishihara Sangyo Kaisha Ltd N−ピリジル−n’−ベンゾイルウレア系化合物及びそれらを含有する殺虫剤
JPH0822851B2 (ja) * 1987-09-16 1996-03-06 北興化学工業株式会社 2,3,5−トリクロロピリジンの製造方法
DE3814358A1 (de) * 1988-04-28 1989-11-09 Ruetgerswerke Ag Verfahren zur herstellung von 2-hydroxypyridin
US4976946A (en) * 1990-02-09 1990-12-11 The Dow Chemical Company Separation of potassium salts
GB9704795D0 (en) * 1997-03-07 1997-04-23 Zeneca Ltd Chemical process

Also Published As

Publication number Publication date
AU5638399A (en) 2000-03-27
CN1314889A (zh) 2001-09-26
CN1134416C (zh) 2004-01-14
JP4302322B2 (ja) 2009-07-22
EP1109788A1 (en) 2001-06-27
BR9913401B1 (pt) 2010-07-13
BR9913401A (pt) 2001-05-22
JP2002524447A (ja) 2002-08-06
US6143899A (en) 2000-11-07
IL141597A (en) 2006-08-20
EP1109788B1 (en) 2004-01-28
KR20010074916A (ko) 2001-08-09
DE69914493D1 (de) 2004-03-04
IL141597A0 (en) 2002-03-10
DK1109788T3 (da) 2004-06-01
WO2000014068A1 (en) 2000-03-16
ES2215397T3 (es) 2004-10-01
GB9819235D0 (en) 1998-10-28
ATE258547T1 (de) 2004-02-15
KR100567197B1 (ko) 2006-04-03

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