DE69913197D1 - Natriumhydrogendivalproat-formulierungen mit gesteuerter freigabe - Google Patents

Natriumhydrogendivalproat-formulierungen mit gesteuerter freigabe

Info

Publication number
DE69913197D1
DE69913197D1 DE69913197T DE69913197T DE69913197D1 DE 69913197 D1 DE69913197 D1 DE 69913197D1 DE 69913197 T DE69913197 T DE 69913197T DE 69913197 T DE69913197 T DE 69913197T DE 69913197 D1 DE69913197 D1 DE 69913197D1
Authority
DE
Germany
Prior art keywords
dival
formulations
program
controlled release
sodium hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69913197T
Other languages
English (en)
Other versions
DE69913197T2 (de
Inventor
Yihong Qui
P Poska
S Cheskin
Daniel Bollinger
R Engh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/216,650 external-priority patent/US6419953B1/en
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of DE69913197D1 publication Critical patent/DE69913197D1/de
Application granted granted Critical
Publication of DE69913197T2 publication Critical patent/DE69913197T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69913197T 1998-12-18 1999-12-09 Natriumhydrogendivalproat-formulierungen mit gesteuerter freigabe Expired - Lifetime DE69913197T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US216650 1994-03-22
US09/216,650 US6419953B1 (en) 1998-12-18 1998-12-18 Controlled release formulation of divalproex sodium
US12155799P 1999-02-25 1999-02-25
US121557P 1999-02-25
PCT/US1999/029204 WO2000037055A1 (en) 1998-12-18 1999-12-09 Controlled release formulation of divalproex sodium

Publications (2)

Publication Number Publication Date
DE69913197D1 true DE69913197D1 (de) 2004-01-08
DE69913197T2 DE69913197T2 (de) 2004-09-02

Family

ID=26819594

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69913197T Expired - Lifetime DE69913197T2 (de) 1998-12-18 1999-12-09 Natriumhydrogendivalproat-formulierungen mit gesteuerter freigabe

Country Status (25)

Country Link
EP (1) EP1140034B1 (de)
JP (1) JP2003513882A (de)
KR (1) KR20010101295A (de)
CN (1) CN1335769A (de)
AR (1) AR021443A1 (de)
AT (1) ATE254907T1 (de)
AU (1) AU2478900A (de)
BG (1) BG105665A (de)
BR (1) BR9916361A (de)
CA (1) CA2330480C (de)
CO (1) CO5160287A1 (de)
CZ (1) CZ20012201A3 (de)
DE (1) DE69913197T2 (de)
DK (1) DK1140034T3 (de)
ES (1) ES2212667T3 (de)
HK (1) HK1043043B (de)
HU (1) HUP0105463A3 (de)
IL (1) IL143407A0 (de)
NO (1) NO20012986L (de)
PL (1) PL356899A1 (de)
PT (1) PT1140034E (de)
SI (1) SI20624A (de)
SK (1) SK8252001A3 (de)
TW (1) TW585788B (de)
WO (1) WO2000037055A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6713086B2 (en) 1998-12-18 2004-03-30 Abbott Laboratories Controlled release formulation of divalproex sodium
US6419953B1 (en) 1998-12-18 2002-07-16 Abbott Laboratories Controlled release formulation of divalproex sodium
US6511678B2 (en) 1998-12-18 2003-01-28 Abbott Laboratories Controlled release formulation of divalproex sodium
US20020025341A1 (en) * 1998-12-18 2002-02-28 Yihong Qiu Controlled release formulation of divalproex sodium
US6528090B2 (en) 1998-12-18 2003-03-04 Abbott Laboratories Controlled release formulation of divalproex sodium
WO2002051402A1 (en) * 2000-12-22 2002-07-04 Abbott Laboratories Controlled release formulation of divalproex sodium
MXPA03010705A (es) * 2001-05-25 2004-05-27 Cephalon Inc Formulaciones farmaceuticas solidas que comprenden modafinil.
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
US20040005357A1 (en) * 2002-07-03 2004-01-08 Sherman Bernard Charles Extended-release tablets comprising divalproex sodium
US20040048931A1 (en) 2002-07-12 2004-03-11 Craig Heacock Modafinil pharmaceutical compositions
US20040116532A1 (en) 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
BRPI0408323A (pt) * 2003-03-14 2006-03-07 Nirmal Mulye processo para a preparação de compimidos de liberação prolongada
HUP0301537A3 (en) * 2003-06-03 2005-07-28 Egis Gyogyszergyar Nyilvanosan Deramcyclane fumarate tablets and process for producing them
US7713550B2 (en) 2004-06-15 2010-05-11 Andrx Corporation Controlled release sodium valproate formulation
WO2006025029A2 (en) * 2004-08-31 2006-03-09 Ranbaxy Laboratories Limited Extended release composition of divalproex
MX2007008985A (es) * 2005-01-26 2007-12-06 Elan Pharma Int Ltd Composiciones de liberacion controlada que comprenden un agente anti-sicotico.
US20070202164A1 (en) * 2006-02-28 2007-08-30 Hutchison Medipharma Enterprises Limited Andrographis Extract Formulations
CN102421428B (zh) * 2009-05-12 2014-01-29 株式会社爱茉莉太平洋 用于防止脱发或促进毛发生长的组合物
WO2012121862A2 (en) * 2011-02-17 2012-09-13 University Of Florida Research Foundation Valproic acid derivative compounds
CN102138911B (zh) * 2011-03-28 2012-12-12 孙卫东 一种双丙戊酸钠缓释片及其制备方法
CN102895201B (zh) * 2011-07-26 2014-09-10 北大方正集团有限公司 丙戊酸半钠片剂及其制备方法
EP2919903B1 (de) 2012-11-14 2020-07-22 W.R. Grace & CO. - CONN. Zusammensetzungen mit einem biologischen wirkstoff und einem nicht geordneten anorganischen oxid
CN105012264B (zh) * 2014-04-16 2019-11-29 四川科瑞德制药股份有限公司 丙戊酸钠缓释片及其制备工艺和用途
CN106389368B (zh) * 2015-07-29 2021-11-12 四川科瑞德制药股份有限公司 一种丙戊酸钠缓释制剂及其制备工艺和用途
CN105456218A (zh) * 2015-12-07 2016-04-06 黑龙江省智诚医药科技有限公司 一种丙戊酸镁缓释片及其制备方法
CN107028907B (zh) * 2016-02-04 2021-05-14 成都康弘药业集团股份有限公司 一种双丙戊酸钠缓释片
CN114681419A (zh) * 2020-12-28 2022-07-01 湖南省湘中制药有限公司 一种丙戊酰胺缓释片的组合物及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169642A (en) * 1988-06-24 1992-12-08 Abbott Laboratories Sustained-release drug dosage units
US5009897A (en) * 1988-06-24 1991-04-23 Abbott Laboratories Pharmaceutical granules and tablets made therefrom
FR2643556B1 (fr) * 1989-02-27 1993-03-05 Sanofi Sa Composition pharmaceutique a liberation prolongee d'acide valproique
IL96311A (en) * 1989-12-01 1995-05-26 Abbott Lab Medications with delayed release
US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
TW224049B (de) * 1991-12-31 1994-05-21 Sunkyong Ind Ltd
TW222585B (de) * 1992-09-11 1994-04-21 Hoechst Ag
JP3552285B2 (ja) * 1993-08-03 2004-08-11 三菱化学株式会社 経口コレステロール低下剤
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
CA2216215A1 (en) * 1997-04-05 1998-10-05 Isa Odidi Controlled release formulations using intelligent polymers having opposing wettability characteristics of hydrophobicity and hydrophilicity

Also Published As

Publication number Publication date
PT1140034E (pt) 2004-03-31
SI20624A (sl) 2002-02-28
CN1335769A (zh) 2002-02-13
EP1140034B1 (de) 2003-11-26
BR9916361A (pt) 2002-11-05
CO5160287A1 (es) 2002-05-30
DK1140034T3 (da) 2004-03-08
HK1043043B (zh) 2004-09-10
NO20012986D0 (no) 2001-06-15
NO20012986L (no) 2001-08-15
TW585788B (en) 2004-05-01
BG105665A (bg) 2002-03-29
KR20010101295A (ko) 2001-11-14
IL143407A0 (en) 2002-04-21
AU2478900A (en) 2000-07-12
HK1043043A1 (en) 2002-09-06
HUP0105463A3 (en) 2003-03-28
ATE254907T1 (de) 2003-12-15
PL356899A1 (en) 2004-07-12
AR021443A1 (es) 2002-07-17
EP1140034A1 (de) 2001-10-10
ES2212667T3 (es) 2004-07-16
WO2000037055A1 (en) 2000-06-29
SK8252001A3 (en) 2001-12-03
HUP0105463A2 (hu) 2002-05-29
JP2003513882A (ja) 2003-04-15
DE69913197T2 (de) 2004-09-02
CA2330480C (en) 2002-05-21
CA2330480A1 (en) 2000-06-29
CZ20012201A3 (cs) 2001-09-12

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Legal Events

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