DE69907249D1 - Mikrofabrizierter zellinjektor - Google Patents

Mikrofabrizierter zellinjektor

Info

Publication number
DE69907249D1
DE69907249D1 DE69907249T DE69907249T DE69907249D1 DE 69907249 D1 DE69907249 D1 DE 69907249D1 DE 69907249 T DE69907249 T DE 69907249T DE 69907249 T DE69907249 T DE 69907249T DE 69907249 D1 DE69907249 D1 DE 69907249D1
Authority
DE
Germany
Prior art keywords
cells
cell
needle
injection
wall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69907249T
Other languages
English (en)
Other versions
DE69907249T2 (de
Inventor
John Garman
John Scanlon
John Dodgson
Edward Shaw
David Brennan
Robert Corless
Matthew Turner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Q FUTURES LTD., CHESTER, CHESHIRE, GB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9821833.2A external-priority patent/GB9821833D0/en
Priority claimed from GBGB9918614.0A external-priority patent/GB9918614D0/en
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE69907249D1 publication Critical patent/DE69907249D1/de
Publication of DE69907249T2 publication Critical patent/DE69907249T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
DE69907249T 1998-10-08 1999-10-07 Mikrofabrizierter zellinjektor Expired - Fee Related DE69907249T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9821833.2A GB9821833D0 (en) 1998-10-08 1998-10-08 Device
GBGB9918614.0A GB9918614D0 (en) 1999-08-07 1999-08-07 Device
PCT/GB1999/003330 WO2000020554A1 (en) 1998-10-08 1999-10-07 Microfabricated cell injector

Publications (2)

Publication Number Publication Date
DE69907249D1 true DE69907249D1 (de) 2003-05-28
DE69907249T2 DE69907249T2 (de) 2004-01-29

Family

ID=26314473

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69907249T Expired - Fee Related DE69907249T2 (de) 1998-10-08 1999-10-07 Mikrofabrizierter zellinjektor

Country Status (7)

Country Link
US (1) US6846668B1 (de)
EP (1) EP1124939B1 (de)
JP (1) JP2002526103A (de)
AT (1) ATE238412T1 (de)
AU (1) AU6216199A (de)
DE (1) DE69907249T2 (de)
WO (1) WO2000020554A1 (de)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2320377C (en) 1998-02-24 2008-07-08 Boston Scientific Limited High flow rate dialysis catheters and related methods
IT1320187B1 (it) 2000-04-21 2003-11-26 Igea Srl Dispositivo e metodo di elettro-porazione che fornisce un segnalemodulato sotto il controllo continuo della elettro-permeabilizzazione
IT1320186B1 (it) * 2000-04-21 2003-11-26 Igea Srl Dispositivo e metodo di elettro-porazione in cui l'ampiezzadell'impulso o degli impulsi viene stabilita in modo automatico in
DE10032568A1 (de) * 2000-07-05 2002-01-24 Nmi Univ Tuebingen Vorrichtung und Verfahren zum elektrischen Kontaktieren von in einer Flüssigkeit in Suspension befindlichen biologischen Zellen
EP1178315A1 (de) * 2000-07-31 2002-02-06 Albrecht Dr.med. Priv.Doz. Lepple-Wienhues Verfahren und Vorrichtung zur Untersuchung von Zellen mit Hilfe der Patch Clamp-Methode
US8251986B2 (en) 2000-08-17 2012-08-28 Angiodynamics, Inc. Method of destroying tissue cells by eletroporation
US6697670B2 (en) 2001-08-17 2004-02-24 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits by electroporation with improved comfort of patients
AU2002246527A1 (en) * 2000-11-28 2002-08-06 Georgetown University Cell transformation using a single chip silicon microfabricated array incorporating integrated micro-piercing injectors
US6994706B2 (en) 2001-08-13 2006-02-07 Minnesota Medical Physics, Llc Apparatus and method for treatment of benign prostatic hyperplasia
JP4051440B2 (ja) * 2002-03-06 2008-02-27 独立行政法人産業技術総合研究所 細胞操作装置及び方法
WO2004001498A1 (ja) * 2002-06-21 2003-12-31 Bridgestone Corporation 画像表示装置及び画像表示装置の製造方法
EP1546348A4 (de) * 2002-08-21 2005-12-14 Cellectricon Ab System und verfahren zur gewinnung und erhaltung hochresistenter verschlüsse bei patch-clamp-aufzeichnungen
WO2004036202A1 (en) 2002-10-16 2004-04-29 Cellectricon Ab Nanoelectrodes and nanotips for recording transmembrane currents in a plurality of cells
IL154677A0 (en) * 2003-02-27 2003-09-17 Univ Bar Ilan A method and apparatus for manipulating an individual cell
US8993327B2 (en) * 2003-04-07 2015-03-31 Ut-Battelle, Llc Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures
JP2004344036A (ja) * 2003-05-21 2004-12-09 Fujitsu Ltd 物質導入装置及び物質導入システム
US9200245B2 (en) 2003-06-26 2015-12-01 Seng Enterprises Ltd. Multiwell plate
DE10336513A1 (de) * 2003-08-08 2005-03-03 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Mikroinjektionseinrichtung und zugehöriges Herstellungsverfahren
DK1696812T3 (en) 2003-12-24 2015-10-26 Univ California Tissue ablation with irreversible electroporation
WO2007021762A2 (en) 2005-08-09 2007-02-22 The University Of North Carolina At Chapel Hill Methods and materials for fabricating microfluidic devices
JP2005278480A (ja) * 2004-03-29 2005-10-13 Fujitsu Ltd 物質導入装置及び物質導入用チップ
JP4504082B2 (ja) 2004-04-28 2010-07-14 富士通株式会社 液体注入装置
US8124032B2 (en) * 2004-07-16 2012-02-28 Simon Fraser University Microfluidic device and method of using same
JP2006055072A (ja) * 2004-08-20 2006-03-02 Fujitsu Ltd 搬送制御装置及び方法
JP4894199B2 (ja) * 2005-02-17 2012-03-14 富士通株式会社 物質注入装置
JP4579745B2 (ja) * 2005-03-31 2010-11-10 富士通株式会社 細胞捕捉装置
JP4677555B2 (ja) * 2005-04-07 2011-04-27 国立大学法人電気通信大学 検体動作制御装置及び方法
US9354156B2 (en) 2007-02-08 2016-05-31 Emd Millipore Corporation Microfluidic particle analysis method, device and system
US9388374B2 (en) 2005-07-07 2016-07-12 Emd Millipore Corporation Microfluidic cell culture systems
US9376658B2 (en) 2008-01-03 2016-06-28 Emd Millipore Corporation Cell culture array system for automated assays and methods of operation and manufacture thereof
US9260688B2 (en) 2005-07-07 2016-02-16 The Regents Of The University Of California Methods and apparatus for cell culture array
US9637715B2 (en) 2005-07-07 2017-05-02 Emd Millipore Corporation Cell culture and invasion assay method and system
US8257964B2 (en) 2006-01-04 2012-09-04 Cell ASIC Microwell cell-culture device and fabrication method
JP4659553B2 (ja) * 2005-08-05 2011-03-30 富士通株式会社 自動マイクロインジェクション装置および細胞捕捉プレート
JP4705439B2 (ja) * 2005-09-09 2011-06-22 富士通株式会社 細胞捕捉シャーレ
MX2008011470A (es) 2006-03-09 2008-09-24 Scripps Research Inst Sistemas para la expresion de componentes de traduccion ortogonales en celulas huesped eubacterianas.
US20070249038A1 (en) * 2006-04-21 2007-10-25 Andrea Adamo Microfluidic device for single cell targeted operations
JP2010500921A (ja) * 2006-08-17 2010-01-14 マサチューセッツ・インスティテュート・オブ・テクノロジー マイクロ流体インジェクションのための方法と装置
US20080213899A1 (en) * 2006-10-12 2008-09-04 University Of Connecticut Rotationally Oscillating Injector
US8076124B2 (en) 2007-01-17 2011-12-13 Ut-Battelle, Llc Method and apparatus for sustaining viability of biological cells on a substrate
JP4946687B2 (ja) * 2007-07-18 2012-06-06 富士通株式会社 マイクロインジェクション装置および流体の注入方法
US9145540B1 (en) 2007-11-15 2015-09-29 Seng Enterprises Ltd. Device for the study of living cells
US9975118B2 (en) 2007-11-15 2018-05-22 Seng Enterprises Ltd. Device for the study of living cells
KR100967850B1 (ko) * 2008-01-22 2010-07-05 한국과학기술원 자동 멀티 셀 주입장치 및 주입방법
KR100967849B1 (ko) * 2008-01-22 2010-07-05 한국과학기술원 자동 세포주입장치 및 세포주입방법
WO2009121017A1 (en) 2008-03-27 2009-10-01 The Regents Of The University Of California Balloon catheter for reducing restenosis via irreversible electroporation
US11272979B2 (en) 2008-04-29 2022-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US10238447B2 (en) 2008-04-29 2019-03-26 Virginia Tech Intellectual Properties, Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US10117707B2 (en) 2008-04-29 2018-11-06 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US8992517B2 (en) 2008-04-29 2015-03-31 Virginia Tech Intellectual Properties Inc. Irreversible electroporation to treat aberrant cell masses
US9198733B2 (en) 2008-04-29 2015-12-01 Virginia Tech Intellectual Properties, Inc. Treatment planning for electroporation-based therapies
US10702326B2 (en) 2011-07-15 2020-07-07 Virginia Tech Intellectual Properties, Inc. Device and method for electroporation based treatment of stenosis of a tubular body part
US10272178B2 (en) 2008-04-29 2019-04-30 Virginia Tech Intellectual Properties Inc. Methods for blood-brain barrier disruption using electrical energy
AU2009243079A1 (en) 2008-04-29 2009-11-05 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation to create tissue scaffolds
US9283051B2 (en) 2008-04-29 2016-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating a treatment volume for administering electrical-energy based therapies
US10448989B2 (en) 2009-04-09 2019-10-22 Virginia Tech Intellectual Properties, Inc. High-frequency electroporation for cancer therapy
US9867652B2 (en) 2008-04-29 2018-01-16 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
US10245098B2 (en) 2008-04-29 2019-04-02 Virginia Tech Intellectual Properties, Inc. Acute blood-brain barrier disruption using electrical energy based therapy
US11254926B2 (en) 2008-04-29 2022-02-22 Virginia Tech Intellectual Properties, Inc. Devices and methods for high frequency electroporation
US7892399B2 (en) * 2008-05-29 2011-02-22 Honeywell Asca Inc. Local tension generating air stabilization system for web products
WO2009155526A2 (en) 2008-06-20 2009-12-23 Angiodynamics, Inc. Device and method for the ablation of fibrin sheath formation on a venous catheter
US9681909B2 (en) 2008-06-23 2017-06-20 Angiodynamics, Inc. Treatment devices and methods
US20100081928A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological Facilitation systems and methods
US20100081916A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware. Histological facilitation systems and methods
US20100081927A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081915A1 (en) * 2008-09-29 2010-04-01 Searete Llc, Alimited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081924A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081926A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
CA2685615C (en) * 2008-10-10 2018-01-16 Mcmaster University Single cell microinjection using flexible and compliant fluidic channels and electroosomotic dosage control
US8162149B1 (en) 2009-01-21 2012-04-24 Sandia Corporation Particle sorter comprising a fluid displacer in a closed-loop fluid circuit
WO2010118387A1 (en) 2009-04-09 2010-10-14 Virginia Tech Intellectual Properties, Inc. Integration of very short electric pulses for minimally to noninvasive electroporation
US11382681B2 (en) 2009-04-09 2022-07-12 Virginia Tech Intellectual Properties, Inc. Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
US11638603B2 (en) 2009-04-09 2023-05-02 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
WO2010138919A2 (en) 2009-05-28 2010-12-02 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
US20110118732A1 (en) 2009-11-19 2011-05-19 The Regents Of The University Of California Controlled irreversible electroporation
US9353342B2 (en) 2010-01-21 2016-05-31 Emd Millipore Corporation Cell culture and gradient migration assay methods and devices
US9700368B2 (en) 2010-10-13 2017-07-11 Angiodynamics, Inc. System and method for electrically ablating tissue of a patient
US10526572B2 (en) 2011-04-01 2020-01-07 EMD Millipore Corporaticn Cell culture and invasion assay method and system
US8785177B2 (en) 2011-11-04 2014-07-22 The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois Methods for nano-mechanoporation
SG10201604400RA (en) 2011-12-03 2016-07-28 Emd Millipore Corp Micro-incubation systems for microfluidic cell culture and methods
US9394547B2 (en) * 2012-01-03 2016-07-19 City University Of Hong Kong Method and apparatus for delivery of molecules to cells
US9414881B2 (en) 2012-02-08 2016-08-16 Angiodynamics, Inc. System and method for increasing a target zone for electrical ablation
WO2013126556A1 (en) * 2012-02-21 2013-08-29 Indiana University Research And Technology Corporation Ultrahigh throughput microinjection device
JP6317353B2 (ja) * 2012-09-13 2018-04-25 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 固形組織の単細胞における多重分析測定のための方法
US9888956B2 (en) 2013-01-22 2018-02-13 Angiodynamics, Inc. Integrated pump and generator device and method of use
JP6377063B2 (ja) * 2013-08-30 2018-08-22 国立研究開発法人科学技術振興機構 プレーナーパッチクランプ装置及びプレーナーパッチクランプシステム
US10166321B2 (en) 2014-01-09 2019-01-01 Angiodynamics, Inc. High-flow port and infusion needle systems
CN112807074A (zh) 2014-05-12 2021-05-18 弗吉尼亚暨州立大学知识产权公司 电穿孔系统
DE102014015418B3 (de) * 2014-10-20 2015-11-19 Technische Universität Braunschweig Mikrosystem und Verfahren zur Manipulation von biologischem Material
WO2016100325A1 (en) 2014-12-15 2016-06-23 Virginia Tech Intellectual Properties, Inc. Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
US10660691B2 (en) 2015-10-07 2020-05-26 Angiodynamics, Inc. Multiple use subassembly with integrated fluid delivery system for use with single or dual-lumen peristaltic tubing
US20170191912A1 (en) 2016-01-06 2017-07-06 International Business Machines Corporation Semiconductor manufactured nano-structures for microbe or virus trapping or destruction
US20170333901A1 (en) * 2016-05-17 2017-11-23 City University Of Hong Kong Cell-trapping device, apparatus comprising it and their use for microinjection into cells
WO2018081298A1 (en) * 2016-10-26 2018-05-03 President And Fellows Of Harvard College Systems and methods for injection of biological specimens
US10905492B2 (en) 2016-11-17 2021-02-02 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
KR20200043369A (ko) * 2017-06-16 2020-04-27 님 싸이언티픽 인코포레이티드 나노 니들 및 관련된 기기 및 방법
US11015161B2 (en) * 2017-09-06 2021-05-25 The Charles Stark Draper Laboratory, Inc. Electroporation aided biological material delivery system and method
US11607537B2 (en) 2017-12-05 2023-03-21 Virginia Tech Intellectual Properties, Inc. Method for treating neurological disorders, including tumors, with electroporation
US11925405B2 (en) 2018-03-13 2024-03-12 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
US11311329B2 (en) 2018-03-13 2022-04-26 Virginia Tech Intellectual Properties, Inc. Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
US20190292511A1 (en) * 2018-03-20 2019-09-26 Owl biomedical, Inc. Microfabricated particle manipulation device
CN112840015A (zh) * 2018-11-12 2021-05-25 飞秒生物医学有限公司 控制细胞内递送物质的方法及装置
US11950835B2 (en) 2019-06-28 2024-04-09 Virginia Tech Intellectual Properties, Inc. Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy
LT2020027A (lt) 2020-07-14 2022-01-25 Uab "Femtika" Ląstelių mikroporatorius
WO2022213070A1 (en) * 2021-03-29 2022-10-06 Mekonos Inc. Scalable systems and methods for automated biosystem engineering
WO2023215325A1 (en) * 2022-05-03 2023-11-09 Basilard Biotech, Inc. Deterministic mechanoporation devices, systems and methods

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0648975B2 (ja) 1989-10-02 1994-06-29 俊郎 樋口 微小インジェクション装置及びそのインジェクション制御方法
US5262128A (en) * 1989-10-23 1993-11-16 The United States Of America As Represented By The Department Of Health And Human Services Array-type multiple cell injector
US5770029A (en) 1996-07-30 1998-06-23 Soane Biosciences Integrated electrophoretic microdevices
CA2134478C (en) 1992-05-01 2001-12-18 Peter Wilding Microfabricated detection structures
US5296375A (en) 1992-05-01 1994-03-22 Trustees Of The University Of Pennsylvania Mesoscale sperm handling devices
JP3402635B2 (ja) 1992-12-08 2003-05-06 キヤノン株式会社 微小流路素子
US5457041A (en) * 1994-03-25 1995-10-10 Science Applications International Corporation Needle array and method of introducing biological substances into living cells using the needle array
CA2201315A1 (en) * 1994-09-30 1996-04-11 Peter Ping Ling Direct introduction of foreign materials into cells
US5716852A (en) 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
US6267858B1 (en) 1996-06-28 2001-07-31 Caliper Technologies Corp. High throughput screening assay systems in microscale fluidic devices
WO1998028406A1 (en) * 1996-12-20 1998-07-02 Genesystems, Inc. Method and device for microinjection of macromolecules into non-adherent cells
US6083763A (en) 1996-12-31 2000-07-04 Genometrix Inc. Multiplexed molecular analysis apparatus and method
CA2230653A1 (en) 1998-02-27 1999-08-27 The Governors Of The University Of Alberta Microchip based enzymatic analysis

Also Published As

Publication number Publication date
WO2000020554A1 (en) 2000-04-13
ATE238412T1 (de) 2003-05-15
WO2000020554A9 (en) 2000-08-24
DE69907249T2 (de) 2004-01-29
JP2002526103A (ja) 2002-08-20
EP1124939A1 (de) 2001-08-22
US6846668B1 (en) 2005-01-25
EP1124939B1 (de) 2003-04-23
AU6216199A (en) 2000-04-26

Similar Documents

Publication Publication Date Title
DE69907249T2 (de) Mikrofabrizierter zellinjektor
TR200100736T2 (tr) İğnesiz enjektör kartuşu.
DE3668426D1 (de) Schaumerzeuger.
BR0105308A (pt) Filtro para combustìvel de motor a diesel
TNSN05103A1 (en) Fuel filter for diesel engines with high pressure direct injection of common rail type and the like
BR0017069A (pt) Aparelho de oxigenação, método para a oxigenação de um lìquido com ele e aplicações dos mesmos
ATE27638T1 (de) Kraftstoffeinspritzpumpe.
IT8553965V0 (it) Valvola di mandata a pressione costante per pompe di iniezione del combustibile per motori a ciclo diesel
ES8706050A1 (es) Un sistema de limpieza para inyectores de combustible
ATE183663T1 (de) Zentrifugale flüssigkeitspumpe mit inwendiger gasinjektionsvorrichting
IT8567511A1 (it) Sistema di alimentazione di carburante all'avviamento di un motore endotermico comprendente un sistema di iniezione elettronica.
AR044372A1 (es) Conjunto y metodo de flujo de fluidos para la utilizacion de combustibles en celulas de combustible electroquimicas
GB1415539A (en) Liquid injection system
JPS55112855A (en) Constant pressure type fuel injection valve
ES462002A1 (es) Perfeccionamientos en sistemas catalizadores de vapor para aparatos de combustion de combustible fosil.
SE9900825D0 (sv) Anordning för hantering av sprängämneskompositioner
IT1020703B (it) Perfezionamenti nelle pompe di inie zione per motori diesel con regola zione elettronica della portata
IT207880Z2 (it) Dispositivo atto a mantenere sostanzialmente costante la pressione di un liquido in un circuito idraulico in particolare nel circuito di un impianto di iniezione del carburante per un motore a combustione in terna
SE9501387D0 (sv) Bränslematningssystem
IT8647629A0 (it) Pompe di alimentazione del carburante, in particolare pompe a membrana azionate dal motore a combustione interna e connesse direttamente a questo
IT1256864B (it) Sistema di innesco a due volumi per carburatore
SU1361774A1 (ru) Устройство для ввода химреагентов в поток жидкости
RU94008010A (ru) Устройство для насыщения крови кислородом
ES501759A0 (es) Perfeccionamientos en bombas de inyeccion de combustible liquido
JPS56143808A (en) Device for generating alternately positive and negative pressure of liquid

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: Q FUTURES LTD., CHESTER, CHESHIRE, GB

8328 Change in the person/name/address of the agent

Representative=s name: JANNIG & REPKOW PATENTANWAELTE, 86199 AUGSBURG

8339 Ceased/non-payment of the annual fee