DE69838249D1 - Anti-apo-2 antikörper - Google Patents
Anti-apo-2 antikörperInfo
- Publication number
- DE69838249D1 DE69838249D1 DE69838249T DE69838249T DE69838249D1 DE 69838249 D1 DE69838249 D1 DE 69838249D1 DE 69838249 T DE69838249 T DE 69838249T DE 69838249 T DE69838249 T DE 69838249T DE 69838249 D1 DE69838249 D1 DE 69838249D1
- Authority
- DE
- Germany
- Prior art keywords
- apo
- antibodies
- chimeras
- nucleic acid
- acid encoding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85721697A | 1997-05-15 | 1997-05-15 | |
US857216 | 1997-05-15 | ||
US2074698A | 1998-02-09 | 1998-02-09 | |
US20746 | 1998-02-09 | ||
EP98926036A EP0981618B2 (de) | 1997-05-15 | 1998-05-14 | Anti-apo-2 antikörper |
PCT/US1998/009704 WO1998051793A1 (en) | 1997-05-15 | 1998-05-14 | Apo-2 RECEPTOR |
Publications (3)
Publication Number | Publication Date |
---|---|
DE69838249D1 true DE69838249D1 (de) | 2007-09-27 |
DE69838249T2 DE69838249T2 (de) | 2008-05-15 |
DE69838249T3 DE69838249T3 (de) | 2012-01-19 |
Family
ID=26693808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69838249T Expired - Lifetime DE69838249T3 (de) | 1997-05-15 | 1998-05-14 | Anti-apo-2 antikörper |
Country Status (13)
Country | Link |
---|---|
US (1) | US20030017161A1 (de) |
EP (2) | EP0981618B2 (de) |
JP (3) | JP2001511653A (de) |
AT (2) | ATE516354T1 (de) |
CA (1) | CA2287911C (de) |
CY (1) | CY1106966T1 (de) |
DE (1) | DE69838249T3 (de) |
DK (2) | DK1860187T3 (de) |
ES (1) | ES2293682T5 (de) |
HK (1) | HK1109423A1 (de) |
IL (1) | IL132067A0 (de) |
PT (2) | PT1860187E (de) |
WO (1) | WO1998051793A1 (de) |
Families Citing this family (127)
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US20040136951A1 (en) * | 1997-03-17 | 2004-07-15 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
US20050233958A1 (en) * | 1997-03-17 | 2005-10-20 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
DK0970213T3 (da) | 1997-03-17 | 2007-05-21 | Human Genome Sciences Inc | Dödsdomæneholdig receptor |
US20080248046A1 (en) * | 1997-03-17 | 2008-10-09 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
US6872568B1 (en) * | 1997-03-17 | 2005-03-29 | Human Genome Sciences, Inc. | Death domain containing receptor 5 antibodies |
EP1788086A1 (de) * | 1997-03-17 | 2007-05-23 | Human Genome Sciences, Inc. | Rezeptor 5, der eine für den Zelltod verantwortliche Domäne enthält |
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US20100152426A1 (en) * | 1997-05-15 | 2010-06-17 | Ashkenazi Avi J | Apo-2 receptor fusion proteins |
AU9376498A (en) * | 1997-09-05 | 1999-03-22 | University Of Washington | Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents |
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DE60028971T2 (de) * | 1999-06-09 | 2007-02-08 | Genentech, Inc., South San Francisco | Apo-2l rezeptor-agonist und cpt-11 synergie-effekt |
MXPA01013236A (es) | 1999-06-28 | 2002-06-21 | Genentech Inc | Metodos para hacer ligando apo-2 mediante el uso de iones metalicos divalentes. |
IL148266A0 (en) * | 1999-09-15 | 2002-09-12 | Genentech Inc | Apo-2 receptor antibodies |
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US7279160B2 (en) | 2000-05-02 | 2007-10-09 | The Uab Research Foundation | Combinations of DR5 antibodies and other therapeutic agents |
TWI318983B (en) | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
US7476383B2 (en) | 2000-05-02 | 2009-01-13 | The Uab Research Foundation | Antibody selective for DR4 and uses thereof |
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1998
- 1998-05-14 EP EP98926036A patent/EP0981618B2/de not_active Expired - Lifetime
- 1998-05-14 PT PT07002962T patent/PT1860187E/pt unknown
- 1998-05-14 JP JP54946098A patent/JP2001511653A/ja not_active Withdrawn
- 1998-05-14 PT PT98926036T patent/PT981618E/pt unknown
- 1998-05-14 AT AT07002962T patent/ATE516354T1/de active
- 1998-05-14 IL IL13206798A patent/IL132067A0/xx unknown
- 1998-05-14 DK DK07002962.4T patent/DK1860187T3/da active
- 1998-05-14 DK DK98926036.9T patent/DK0981618T4/da active
- 1998-05-14 WO PCT/US1998/009704 patent/WO1998051793A1/en active IP Right Grant
- 1998-05-14 ES ES98926036T patent/ES2293682T5/es not_active Expired - Lifetime
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- 2007-12-10 JP JP2007318714A patent/JP2008148695A/ja active Pending
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Also Published As
Publication number | Publication date |
---|---|
ES2293682T5 (es) | 2011-11-17 |
CY1106966T1 (el) | 2012-09-26 |
JP2001511653A (ja) | 2001-08-14 |
EP1860187B1 (de) | 2011-07-13 |
US20030017161A1 (en) | 2003-01-23 |
ATE516354T1 (de) | 2011-07-15 |
EP0981618B2 (de) | 2011-08-24 |
CA2287911A1 (en) | 1998-11-19 |
JP2010075184A (ja) | 2010-04-08 |
IL132067A0 (en) | 2001-03-19 |
PT1860187E (pt) | 2011-10-04 |
ATE370232T1 (de) | 2007-09-15 |
EP0981618A1 (de) | 2000-03-01 |
EP0981618B1 (de) | 2007-08-15 |
AU7796398A (en) | 1998-12-08 |
JP2008148695A (ja) | 2008-07-03 |
HK1109423A1 (en) | 2008-06-06 |
DK0981618T3 (da) | 2007-11-26 |
EP1860187A1 (de) | 2007-11-28 |
PT981618E (pt) | 2007-11-23 |
WO1998051793A1 (en) | 1998-11-19 |
DK0981618T4 (da) | 2011-11-21 |
ES2293682T3 (es) | 2008-03-16 |
DK1860187T3 (da) | 2011-10-31 |
CA2287911C (en) | 2014-05-06 |
DE69838249T2 (de) | 2008-05-15 |
AU740858B2 (en) | 2001-11-15 |
DE69838249T3 (de) | 2012-01-19 |
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