DE69836088D1 - Als lerk6 bezeichnetes cytokin - Google Patents

Als lerk6 bezeichnetes cytokin

Info

Publication number
DE69836088D1
DE69836088D1 DE69836088T DE69836088T DE69836088D1 DE 69836088 D1 DE69836088 D1 DE 69836088D1 DE 69836088 T DE69836088 T DE 69836088T DE 69836088 T DE69836088 T DE 69836088T DE 69836088 D1 DE69836088 D1 DE 69836088D1
Authority
DE
Germany
Prior art keywords
lerk6
cytokin
designated
lerk
purified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69836088T
Other languages
English (en)
Other versions
DE69836088T2 (de
Inventor
P Cerretti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunex Corp
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of DE69836088D1 publication Critical patent/DE69836088D1/de
Publication of DE69836088T2 publication Critical patent/DE69836088T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00089—Wound bandages
    • A61F2013/00153—Wound bandages coloured or with decoration pattern or printing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69836088T 1997-08-29 1998-08-27 Als lerk6 bezeichnetes cytokin Expired - Fee Related DE69836088T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/920,440 US5919905A (en) 1994-10-05 1997-08-29 Cytokine designated LERK-6
US920440 1997-08-29
PCT/US1998/017772 WO1999010495A1 (en) 1997-08-29 1998-08-27 Cytokine designated lerk-6

Publications (2)

Publication Number Publication Date
DE69836088D1 true DE69836088D1 (de) 2006-11-16
DE69836088T2 DE69836088T2 (de) 2007-05-16

Family

ID=25443749

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69836088T Expired - Fee Related DE69836088T2 (de) 1997-08-29 1998-08-27 Als lerk6 bezeichnetes cytokin

Country Status (12)

Country Link
US (4) US5919905A (de)
EP (1) EP1009832B1 (de)
JP (1) JP2003532365A (de)
AT (1) ATE341627T1 (de)
AU (1) AU754368B2 (de)
CA (1) CA2301497A1 (de)
DE (1) DE69836088T2 (de)
DK (1) DK1009832T3 (de)
ES (1) ES2273438T3 (de)
NZ (1) NZ502884A (de)
PT (1) PT1009832E (de)
WO (1) WO1999010495A1 (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
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USRE37582E1 (en) 1994-10-05 2002-03-12 Immunex Corporation Cytokine designated LERK-6
US5919905A (en) * 1994-10-05 1999-07-06 Immunex Corporation Cytokine designated LERK-6
US20030228600A1 (en) * 2000-07-14 2003-12-11 Eppendorf 5 Prime, Inc. DNA isolation method and kit
AU2003209272A1 (en) * 2002-01-16 2003-09-02 Zyomyx, Inc. Engineered binding proteins
EP1504102A2 (de) 2002-05-21 2005-02-09 Resistentia Pharmaceuticals AB Chimäre ige-polypeptide und wirtszellen
AU2003268345A1 (en) 2002-09-24 2004-04-19 The Burnham Institute Novel agents that modulate eph receptor activity
CN103880955A (zh) 2003-07-18 2014-06-25 安姆根有限公司 肝细胞生长因子的特异性结合物
DE602006017964D1 (de) 2005-01-27 2010-12-16 Burnham Inst La Jolla Ephb-rezeptorbindende peptide
PE20121506A1 (es) 2006-07-14 2012-11-26 Amgen Inc Compuestos triazolopiridinas como inhibidores de c-met
US8217177B2 (en) 2006-07-14 2012-07-10 Amgen Inc. Fused heterocyclic derivatives and methods of use
JP2010519204A (ja) 2007-02-16 2010-06-03 アムジエン・インコーポレーテツド 窒素含有複素環ケトン類およびそれらのｃ−Ｍｅｔ阻害薬としての使用
WO2009026303A1 (en) 2007-08-21 2009-02-26 Amgen Inc. Human c-fms antigen binding proteins
RU2592672C9 (ru) 2010-12-08 2016-11-27 СтемСентРкс, Инк. Новые модуляторы и способы их применения
DK2937349T3 (en) 2011-03-23 2017-02-20 Amgen Inc CONDENSED TRICYCLIC DUAL INHIBITORS OF CDK 4/6 AND FLT3
US9745288B2 (en) 2011-08-16 2017-08-29 Indiana University Research And Technology Corporation Compounds and methods for treating cancer by inhibiting the urokinase receptor
AR090263A1 (es) 2012-03-08 2014-10-29 Hoffmann La Roche Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
WO2014036022A1 (en) 2012-08-29 2014-03-06 Amgen Inc. Quinazolinone compounds and derivatives thereof
UY35148A (es) 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
WO2014144817A2 (en) 2013-03-15 2014-09-18 Amgen Inc. Inhibitory polypeptides specific to wnt inhibitors
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
US11427627B2 (en) 2013-09-05 2022-08-30 Amgen Inc. Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles
US9381205B2 (en) 2013-11-04 2016-07-05 Pfizer, Inc. Anti-EFNA4 antibody-drug conjugates
MX2016014761A (es) 2014-05-16 2017-05-25 Amgen Inc Ensayo para detectar poblaciones celulares linfocitos t colaboradores 1 (th1) y linfocitos t colaboradores (th2).
US10993891B2 (en) * 2014-12-19 2021-05-04 L'oreal Solid anhydrous cosmetic composition, preparation process, cosmetic treatment processes and associated kit
KR102380150B1 (ko) 2016-03-08 2022-03-29 얀센 바이오테크 인코포레이티드 Gitr 항체, 방법, 및 용도
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MA47775A (fr) 2017-03-14 2020-01-22 Amgen Inc Contrôle des glycoformes afucosylées totales d'anticorps produits en culture cellulaire
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EP4141005B1 (de) 2017-09-08 2024-04-03 Amgen Inc. Inhibitoren von kras g12c und verfahren zur verwendung davon
MA52186A (fr) 2018-03-26 2021-02-17 Amgen Inc Glycoformes afucosylées totales d'anticorps produits en culture cellulaire
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MA52564A (fr) 2018-05-10 2021-03-17 Amgen Inc Inhibiteurs de kras g12c pour le traitement du cancer
MA52765A (fr) 2018-06-01 2021-04-14 Amgen Inc Inhibiteurs de kras g12c et leurs procédés d'utilisation
MA52780A (fr) 2018-06-11 2021-04-14 Amgen Inc Inhibiteurs de kras g12c pour le traitement du cancer
MA51848A (fr) 2018-06-12 2021-04-21 Amgen Inc Inhibiteurs de kras g12c et leurs procédés d'utilisation
CA3117221A1 (en) 2018-11-16 2020-05-22 Amgen Inc. Improved synthesis of key intermediate of kras g12c inhibitor compound
JP7377679B2 (ja) 2018-11-19 2023-11-10 アムジエン・インコーポレーテツド がん治療のためのｋｒａｓｇ１２ｃ阻害剤及び１種以上の薬学的に活性な追加の薬剤を含む併用療法
AU2019384118A1 (en) 2018-11-19 2021-05-27 Amgen Inc. KRAS G12C inhibitors and methods of using the same
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CN114144414A (zh) 2019-05-21 2022-03-04 美国安进公司 固态形式
JP2022542392A (ja) 2019-08-02 2022-10-03 アムジエン・インコーポレーテツド Ｋｉｆ１８ａ阻害剤としてのピリジン誘導体
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WO2021055728A1 (en) 2019-09-18 2021-03-25 Merck Sharp & Dohme Corp. Small molecule inhibitors of kras g12c mutant
US20220349898A1 (en) 2019-09-26 2022-11-03 Amgen Inc. Methods of producing antibody compositions
WO2021081212A1 (en) 2019-10-24 2021-04-29 Amgen Inc. Pyridopyrimidine derivatives useful as kras g12c and kras g12d inhibitors in the treatment of cancer
MX2022005053A (es) 2019-10-28 2022-05-18 Merck Sharp & Dohme Llc Inhibidores de peque?as moleculas de mutante g12c de kras.
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Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
CA2148484A1 (en) * 1992-11-13 1994-05-26 Stewart Lyman Novel cytokine designated elk ligand
US5516658A (en) * 1993-08-20 1996-05-14 Immunex Corporation DNA encoding cytokines that bind the cell surface receptor hek
US5457048A (en) * 1993-12-03 1995-10-10 La Jolla Cancer Research Foundation Eph-related tyrosine kinases, nucleotide sequences and methods of use
US6268476B1 (en) * 1994-09-19 2001-07-31 President And Fellows Of Harvard College EPH receptor ligands, and uses related thereto
US5795734A (en) * 1994-09-19 1998-08-18 President And Fellows Of Harvard College EPH receptor ligands, and uses related thereto
US5919905A (en) * 1994-10-05 1999-07-06 Immunex Corporation Cytokine designated LERK-6
EP0785716B1 (de) * 1994-10-05 2006-11-29 Immunex Corporation Als lerk6 bezeichnetes cytokin
ES2240981T3 (es) * 1994-12-06 2005-10-16 Immunex Corporation Citocina denominada lerk-7.
US6057124A (en) * 1995-01-27 2000-05-02 Amgen Inc. Nucleic acids encoding ligands for HEK4 receptors

Also Published As

Publication number Publication date
AU754368B2 (en) 2002-11-14
WO1999010495A1 (en) 1999-03-04
JP2003532365A (ja) 2003-11-05
DE69836088T2 (de) 2007-05-16
EP1009832B1 (de) 2006-10-04
ATE341627T1 (de) 2006-10-15
NZ502884A (en) 2002-04-26
PT1009832E (pt) 2007-01-31
US6194172B1 (en) 2001-02-27
DK1009832T3 (da) 2007-02-12
CA2301497A1 (en) 1999-03-04
ES2273438T3 (es) 2007-05-01
AU9294598A (en) 1999-03-16
EP1009832A1 (de) 2000-06-21
US6232447B1 (en) 2001-05-15
US6472174B1 (en) 2002-10-29
US5919905A (en) 1999-07-06

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