DK0970213T3 - Dödsdomæneholdig receptor - Google Patents
Dödsdomæneholdig receptorInfo
- Publication number
- DK0970213T3 DK0970213T3 DK98912966T DK98912966T DK0970213T3 DK 0970213 T3 DK0970213 T3 DK 0970213T3 DK 98912966 T DK98912966 T DK 98912966T DK 98912966 T DK98912966 T DK 98912966T DK 0970213 T3 DK0970213 T3 DK 0970213T3
- Authority
- DK
- Denmark
- Prior art keywords
- death domain
- containing receptor
- proteins
- antagonists
- receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4084697P | 1997-03-17 | 1997-03-17 | |
US5402197P | 1997-07-29 | 1997-07-29 | |
PCT/US1998/005377 WO1998041629A2 (en) | 1997-03-17 | 1998-03-17 | Death domain containing receptor 5 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0970213T3 true DK0970213T3 (da) | 2007-05-21 |
Family
ID=26717514
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98912966T DK0970213T3 (da) | 1997-03-17 | 1998-03-17 | Dödsdomæneholdig receptor |
Country Status (15)
Country | Link |
---|---|
US (2) | US7803615B1 (da) |
EP (1) | EP0970213B1 (da) |
JP (2) | JP4330180B2 (da) |
KR (1) | KR100527638B1 (da) |
CN (2) | CN1624128A (da) |
AT (1) | ATE352618T1 (da) |
AU (1) | AU747635B2 (da) |
CA (2) | CA2285040C (da) |
DE (1) | DE69836956T2 (da) |
DK (1) | DK0970213T3 (da) |
ES (1) | ES2281126T3 (da) |
HK (1) | HK1025352A1 (da) |
NZ (2) | NZ337795A (da) |
PT (1) | PT970213E (da) |
WO (1) | WO1998041629A2 (da) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7888466B2 (en) | 1996-01-11 | 2011-02-15 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor HSATU68 |
WO1997033904A1 (en) | 1996-03-12 | 1997-09-18 | Human Genome Sciences, Inc. | Death domain containing receptors |
US6713061B1 (en) | 1996-03-12 | 2004-03-30 | Human Genome Sciences, Inc. | Death domain containing receptors |
US7357927B2 (en) | 1996-03-12 | 2008-04-15 | Human Genome Sciences, Inc. | Death domain containing receptors |
US6635743B1 (en) | 1996-03-22 | 2003-10-21 | Human Genome Sciences, Inc. | Apoptosis inducing molecule II and methods of use |
US7964190B2 (en) | 1996-03-22 | 2011-06-21 | Human Genome Sciences, Inc. | Methods and compositions for decreasing T-cell activity |
US6433147B1 (en) | 1997-01-28 | 2002-08-13 | Human Genome Sciences, Inc. | Death domain containing receptor-4 |
US7452538B2 (en) | 1997-01-28 | 2008-11-18 | Human Genome Sciences, Inc. | Death domain containing receptor 4 antibodies and methods |
US8329179B2 (en) | 1997-01-28 | 2012-12-11 | Human Genome Sciences, Inc. | Death domain containing receptor 4 antibodies and methods |
ATE362982T1 (de) | 1997-01-28 | 2007-06-15 | Human Genome Sciences Inc | ßDEATH-DOMAINß-ENTHALTENDER REZEPTOR 4 (DR4), EIN MITGLIED DER TNF-REZEPTOR SUPERFAMILIE, WELCHER AN TRAIL (APO-2L) BINDET |
US7528239B1 (en) * | 1997-02-13 | 2009-05-05 | Immunex Corporation | Receptor that binds trail |
US6072047A (en) * | 1997-02-13 | 2000-06-06 | Immunex Corporation | Receptor that binds trail |
US20080248046A1 (en) * | 1997-03-17 | 2008-10-09 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
CN1624128A (zh) | 1997-03-17 | 2005-06-08 | 人类基因组科学公司 | 包含死亡结构域的受体-5 |
US6872568B1 (en) | 1997-03-17 | 2005-03-29 | Human Genome Sciences, Inc. | Death domain containing receptor 5 antibodies |
US20050233958A1 (en) * | 1997-03-17 | 2005-10-20 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
US20100152426A1 (en) * | 1997-05-15 | 2010-06-17 | Ashkenazi Avi J | Apo-2 receptor fusion proteins |
JP2001511653A (ja) * | 1997-05-15 | 2001-08-14 | ジェネンテク,インコーポレイテッド | Apo−2レセプター |
US6342369B1 (en) * | 1997-05-15 | 2002-01-29 | Genentech, Inc. | Apo-2-receptor |
WO1999011791A2 (en) * | 1997-09-05 | 1999-03-11 | University Of Washington | Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents |
EP1012179A2 (en) * | 1997-09-12 | 2000-06-28 | Apotech R&D S.A. | Cysteine rich receptors: trail |
WO2001060397A1 (en) | 2000-02-16 | 2001-08-23 | Genentech, Inc. | Uses of agonists and antagonists to modulate activity of tnf-related molecules |
CA2328498A1 (en) * | 1998-06-12 | 1999-12-16 | Genentech, Inc. | Monoclonal antibodies, cross-reactive antibodies and method for producing the same____________________________________ |
WO2000050620A2 (en) | 1999-02-26 | 2000-08-31 | Human Genome Sciences, Inc. | Human endokine alpha and methods of use |
CA2369371A1 (en) * | 1999-05-04 | 2000-11-09 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
AU6928200A (en) * | 1999-08-25 | 2001-03-19 | Genome Therapeutics Corporation | A transmembrane trap for isolating membrane bound proteins |
CA2399391A1 (en) * | 2000-02-11 | 2001-08-16 | Genetics Institute, Llc. | Trade molecules and uses related thereto |
NZ521540A (en) | 2000-04-11 | 2004-09-24 | Genentech Inc | Multivalent antibodies and uses therefor |
US7279160B2 (en) | 2000-05-02 | 2007-10-09 | The Uab Research Foundation | Combinations of DR5 antibodies and other therapeutic agents |
US7476383B2 (en) | 2000-05-02 | 2009-01-13 | The Uab Research Foundation | Antibody selective for DR4 and uses thereof |
TWI318983B (en) | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
WO2001096528A2 (en) | 2000-06-15 | 2001-12-20 | Human Genome Sciences, Inc. | Human tumor necrosis factor delta and epsilon |
NZ522700A (en) | 2000-06-16 | 2006-02-24 | Human Genome Sciences Inc | Antibodies that immunospecifically bind to blys |
EP1303293B1 (en) | 2000-07-27 | 2008-12-03 | Genentech, Inc. | Sequential administration of cpt-11 and apo-2l polypeptide |
US20060062786A1 (en) * | 2000-11-08 | 2006-03-23 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US20030228309A1 (en) * | 2000-11-08 | 2003-12-11 | Theodora Salcedo | Antibodies that immunospecifically bind to TRAIL receptors |
WO2002094880A1 (en) | 2001-05-18 | 2002-11-28 | Kirin Beer Kabushiki Kaisha | Anti-trail-r antibodies |
NZ529359A (en) | 2001-05-25 | 2007-04-27 | Human Genome Sciences Inc | Antibodies that immunospecifically bind to a TR4 polypeptide or polypeptide fragment or variant of TR4 and their use in a medicament for treating cancer |
US20050129616A1 (en) * | 2001-05-25 | 2005-06-16 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US20090226429A1 (en) * | 2001-05-25 | 2009-09-10 | Human Genome Sciences, Inc. | Antibodies That Immunospecifically Bind to TRAIL Receptors |
US7361341B2 (en) * | 2001-05-25 | 2008-04-22 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to trail receptors |
US20050214209A1 (en) * | 2001-05-25 | 2005-09-29 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US7348003B2 (en) | 2001-05-25 | 2008-03-25 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors |
US7252994B2 (en) | 2001-07-03 | 2007-08-07 | Genentech, Inc. | Human DR4 antibodies and uses thereof |
WO2003011318A1 (en) * | 2001-08-01 | 2003-02-13 | Genset S.A. | Agonists and antagonists of famoset for use in the treatment of metabolic disorders |
EP2348043A1 (en) | 2001-10-02 | 2011-07-27 | Genentech, Inc. | APO-2 ligand variants and uses thereof |
EP1439225A4 (en) | 2001-10-04 | 2005-10-26 | Kansai Tech Licensing Org Co | DR5-GEN PROMOTER AND SIAH-1-GEN PROMOTER |
US7842668B1 (en) | 2001-11-13 | 2010-11-30 | Genentech, Inc. | Apo-2 ligand/trail formulations |
DE60237841D1 (de) | 2001-11-13 | 2010-11-11 | Genentech Inc | Zusammensetzungen basierend auf APO2-Ligand/ TRAIL und ihre Verwendung |
US7741285B2 (en) | 2001-11-13 | 2010-06-22 | Genentech, Inc. | APO-2 ligand/trail formulations |
NZ532881A (en) * | 2001-12-20 | 2008-04-30 | Human Genome Sciences Inc | Antibodies that immunospecifically bind to trail receptors |
US20040101915A1 (en) * | 2002-06-18 | 2004-05-27 | Irm Llc, A Delaware Limited Liability Company | Diagnosis and treatment of chemoresistant tumors |
CA2489348A1 (en) | 2002-06-24 | 2003-12-31 | Genentech, Inc. | Apo-2 ligand/trail variants and uses thereof |
CA2560742A1 (en) | 2004-03-23 | 2005-10-06 | Biogen Idec Ma Inc. | Receptor coupling agents and therapeutic uses thereof |
CA2575755C (en) * | 2004-08-06 | 2014-04-08 | Genentech, Inc. | Assays and methods using biomarkers |
CN101035912A (zh) | 2004-08-06 | 2007-09-12 | 健泰科生物技术公司 | 使用生物标志的测定法和方法 |
EP1802660A2 (en) * | 2004-09-08 | 2007-07-04 | Genentech, Inc. | Methods of using death receptor ligands and cd20 antibodies |
NZ553174A (en) * | 2004-09-08 | 2010-03-26 | Genentech Inc | Methods of using death receptor ligands Apo2L/Trail and CD20 antibodies |
JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
CA2595440A1 (en) | 2005-02-02 | 2006-08-10 | The Uab Research Foundation | Agents and methods related to reducing resistance to apoptosis-inducing death receptor agonists |
US8029783B2 (en) | 2005-02-02 | 2011-10-04 | Genentech, Inc. | DR5 antibodies and articles of manufacture containing same |
EP1915626B1 (en) * | 2005-08-16 | 2011-11-09 | Genentech, Inc. | Apoptosis sensitivity to apo2l/trail by testing for galnac-t14 expression in cells/tissues |
PE20071101A1 (es) * | 2005-08-31 | 2007-12-21 | Amgen Inc | Polipeptidos y anticuerpos |
WO2007142667A2 (en) | 2005-10-13 | 2007-12-13 | Human Genome Sciences, Inc. | Treatment of patients with autoantibody positive disease |
WO2007062090A2 (en) | 2005-11-23 | 2007-05-31 | Genentech, Inc. | Methods and compositions related to b cell assays |
US20100105620A1 (en) | 2008-10-10 | 2010-04-29 | Anaphore, Inc. | Polypeptides that bind Trail-R1 and Trail-R2 |
US8790663B2 (en) | 2009-04-03 | 2014-07-29 | Institute Of Basic Medical Sciences, Chinese Academy Of Medical Sciences | Antigenic determinants of human death receptor DR5 |
BR112012005485A2 (pt) | 2009-09-10 | 2016-04-19 | Lonza Biologics Plc | método e sistema para a purificação de polipeptídeo |
CA2780130A1 (en) | 2009-11-05 | 2011-05-12 | The Uab Research Foundation | Treating basal-like genotype cancers |
WO2011116344A2 (en) | 2010-03-18 | 2011-09-22 | The Uab Research Foundation | Targeting cancer stem cells |
BR112013010574A2 (pt) | 2010-10-29 | 2016-08-09 | Daiichi Sankyo Co Ltd | anticorpo, fragmento funcional do anticorpo, composição farmacêutica, usos de um anticorpo ou um fragmento funcional do mesmo e de pelo menos um membro selecionado do grupo que consiste de paclitaxel, carvoplatina, cpt-11, vinblastina, e 5-fu, polinucleotídeo, vetor, célula hospedeira transformada, e, método de produzir o anticorpo |
MX361929B (es) | 2010-11-19 | 2018-12-19 | Eisai R&D Man Co Ltd Star | Anticuerpos anti-ligando de quimiocina cc 20 (ccl20) neutralizantes. |
CA2828405A1 (en) | 2011-02-28 | 2012-09-07 | Istituto Di Ricovero E Cura A Carattere Scientifico Materno-Infantile Bu Rlo Garofolo - Ospedale Di Alta Specializzazione E Di Rilievo Nazionale | Apoptosis-inducing molecules and uses therefor |
EP2704735A1 (en) | 2011-05-03 | 2014-03-12 | Genentech, Inc. | Vascular disruption agents and uses thereof |
US20160067337A1 (en) | 2013-03-14 | 2016-03-10 | Bristol-Myers Squibb Company | Combination of dr5 agonist and anti-pd-1 antagonist and methods of use |
CN105050524B (zh) | 2013-03-22 | 2018-04-03 | 皇家飞利浦有限公司 | 用于使用激光无创处理皮肤的设备 |
CN104693308B (zh) * | 2013-12-05 | 2020-08-04 | 同济大学 | 感受胞内pH变化的Smad5蛋白及其应用 |
EP3323428A1 (en) | 2016-11-17 | 2018-05-23 | CNRS Centre National de la Recherche Scientifique | Selective c-flip inhibitors as anticancer agents |
CN108997503B (zh) * | 2017-06-06 | 2021-07-23 | 深圳市中科艾深医药有限公司 | 人sDR5-Fc重组融合蛋白及其作为制备治疗生殖系统炎症的药物中的应用 |
EP3910331A1 (en) | 2020-05-15 | 2021-11-17 | iOmx Therapeutics AG | Intracellular kinase associated with resistance against t-cell mediated cytotoxicity, and uses thereof |
EP4257132A1 (en) | 2022-04-08 | 2023-10-11 | iOmx Therapeutics AG | Sik3 inhibitors for treating diseases resistant to death receptor signalling |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4002531A (en) * | 1976-01-22 | 1977-01-11 | Pierce Chemical Company | Modifying enzymes with polyethylene glycol and product produced thereby |
US5807715A (en) * | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
US5349053A (en) * | 1990-06-01 | 1994-09-20 | Protein Design Labs, Inc. | Chimeric ligand/immunoglobulin molecules and their uses |
CA2067031C (en) * | 1991-04-26 | 2003-02-18 | Shigekazu Nagata | Dna coding for human cell surface antigen |
IL99120A0 (en) * | 1991-08-07 | 1992-07-15 | Yeda Res & Dev | Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them |
US5565332A (en) * | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
US5447851B1 (en) * | 1992-04-02 | 1999-07-06 | Univ Texas System Board Of | Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells |
GB9214857D0 (en) * | 1992-07-13 | 1992-08-26 | Medical Res Council | Human nucleic acid fragments and their use |
US5643575A (en) * | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
ES2253753T3 (es) * | 1995-06-29 | 2006-06-01 | Immunex Corporation | Citocina que induce apoptosis. |
ATE362982T1 (de) | 1997-01-28 | 2007-06-15 | Human Genome Sciences Inc | ßDEATH-DOMAINß-ENTHALTENDER REZEPTOR 4 (DR4), EIN MITGLIED DER TNF-REZEPTOR SUPERFAMILIE, WELCHER AN TRAIL (APO-2L) BINDET |
US6433147B1 (en) | 1997-01-28 | 2002-08-13 | Human Genome Sciences, Inc. | Death domain containing receptor-4 |
US6072047A (en) | 1997-02-13 | 2000-06-06 | Immunex Corporation | Receptor that binds trail |
US20020160446A1 (en) | 2000-11-14 | 2002-10-31 | Holtzman Douglas A. | Novel genes encoding proteins having prognostic diagnostic preventive therapeutic and other uses |
US20010010924A1 (en) | 1997-03-14 | 2001-08-02 | Keith Charles Deen | Tumor necrosis factor related receptor, tr6 polynecleotides |
US6313269B1 (en) | 1997-03-14 | 2001-11-06 | Smithkline Beecham Corporation | Tumor necrosis factor related receptor, TR6 |
US6872568B1 (en) | 1997-03-17 | 2005-03-29 | Human Genome Sciences, Inc. | Death domain containing receptor 5 antibodies |
CN1624128A (zh) | 1997-03-17 | 2005-06-08 | 人类基因组科学公司 | 包含死亡结构域的受体-5 |
WO1998046643A1 (en) | 1997-04-16 | 1998-10-22 | Millennium Biotherapeutics, Inc. | TUMOR NECROSIS FACTOR RECEPTOR RELATED PROTEINS TANGO-63d AND TANGO-63e |
JP2001511653A (ja) | 1997-05-15 | 2001-08-14 | ジェネンテク,インコーポレイテッド | Apo−2レセプター |
US6342369B1 (en) * | 1997-05-15 | 2002-01-29 | Genentech, Inc. | Apo-2-receptor |
EP1032661A1 (en) | 1997-06-18 | 2000-09-06 | Genentech, Inc. | Apo-2DcR |
JP2002507127A (ja) | 1997-06-26 | 2002-03-05 | イミュネックス・コーポレーション | Trailに結合するタンパク質 |
ATE429450T1 (de) | 1999-05-28 | 2009-05-15 | Genentech Inc | Chimärische dr4 antikörper und ihre verwendung |
WO2000075191A2 (en) | 1999-06-09 | 2000-12-14 | Genentech, Inc. | Apo-2L RECEPTOR AGONIST AND CPT-11 SYNERGISM |
TWI318983B (en) | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
-
1998
- 1998-03-17 CN CNA2004100949179A patent/CN1624128A/zh active Pending
- 1998-03-17 NZ NZ337795A patent/NZ337795A/en not_active IP Right Cessation
- 1998-03-17 PT PT98912966T patent/PT970213E/pt unknown
- 1998-03-17 WO PCT/US1998/005377 patent/WO1998041629A2/en active IP Right Grant
- 1998-03-17 ES ES98912966T patent/ES2281126T3/es not_active Expired - Lifetime
- 1998-03-17 KR KR10-1999-7008466A patent/KR100527638B1/ko not_active IP Right Cessation
- 1998-03-17 DE DE69836956T patent/DE69836956T2/de not_active Revoked
- 1998-03-17 AU AU67635/98A patent/AU747635B2/en not_active Withdrawn - After Issue
- 1998-03-17 EP EP98912966A patent/EP0970213B1/en not_active Revoked
- 1998-03-17 CA CA002285040A patent/CA2285040C/en not_active Expired - Lifetime
- 1998-03-17 NZ NZ508381A patent/NZ508381A/xx not_active IP Right Cessation
- 1998-03-17 CA CA002644454A patent/CA2644454A1/en not_active Abandoned
- 1998-03-17 CN CNB988045370A patent/CN1184315C/zh not_active Expired - Lifetime
- 1998-03-17 AT AT98912966T patent/ATE352618T1/de active
- 1998-03-17 JP JP54079098A patent/JP4330180B2/ja not_active Expired - Fee Related
- 1998-03-17 US US09/042,583 patent/US7803615B1/en not_active Expired - Fee Related
- 1998-03-17 DK DK98912966T patent/DK0970213T3/da active
-
2000
- 2000-07-12 HK HK00104295A patent/HK1025352A1/xx not_active IP Right Cessation
-
2001
- 2001-12-07 US US10/005,842 patent/US20020098550A1/en not_active Abandoned
-
2007
- 2007-10-03 JP JP2007260427A patent/JP2008081503A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DE69836956T2 (de) | 2007-10-31 |
US20020098550A1 (en) | 2002-07-25 |
CN1624128A (zh) | 2005-06-08 |
DE69836956D1 (de) | 2007-03-15 |
US7803615B1 (en) | 2010-09-28 |
AU747635B2 (en) | 2002-05-16 |
CA2644454A1 (en) | 1998-09-24 |
EP0970213B1 (en) | 2007-01-24 |
WO1998041629A3 (en) | 1998-10-29 |
CN1275162A (zh) | 2000-11-29 |
WO1998041629A2 (en) | 1998-09-24 |
CN1184315C (zh) | 2005-01-12 |
JP4330180B2 (ja) | 2009-09-16 |
EP0970213A2 (en) | 2000-01-12 |
CA2285040C (en) | 2009-01-27 |
KR100527638B1 (ko) | 2005-11-23 |
NZ508381A (en) | 2002-09-27 |
AU6763598A (en) | 1998-10-12 |
ES2281126T3 (es) | 2007-09-16 |
JP2001520513A (ja) | 2001-10-30 |
PT970213E (pt) | 2007-04-30 |
HK1025352A1 (en) | 2000-11-10 |
KR20000076364A (ko) | 2000-12-26 |
CA2285040A1 (en) | 1998-09-24 |
NZ337795A (en) | 2001-06-29 |
ATE352618T1 (de) | 2007-02-15 |
JP2008081503A (ja) | 2008-04-10 |
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