DE69534588D1 - Protocadherin-proteine und verwendungen davon - Google Patents

Protocadherin-proteine und verwendungen davon

Info

Publication number
DE69534588D1
DE69534588D1 DE69534588T DE69534588T DE69534588D1 DE 69534588 D1 DE69534588 D1 DE 69534588D1 DE 69534588 T DE69534588 T DE 69534588T DE 69534588 T DE69534588 T DE 69534588T DE 69534588 D1 DE69534588 D1 DE 69534588D1
Authority
DE
Germany
Prior art keywords
protocadherins
protocadherine
proteins
polypeptides
modulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69534588T
Other languages
English (en)
Inventor
Shintaro Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Doheny Eye Institute of USC
Original Assignee
Doheny Eye Institute of USC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Doheny Eye Institute of USC filed Critical Doheny Eye Institute of USC
Application granted granted Critical
Publication of DE69534588D1 publication Critical patent/DE69534588D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69534588T 1994-06-27 1995-06-26 Protocadherin-proteine und verwendungen davon Expired - Lifetime DE69534588D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/268,161 US5798224A (en) 1992-12-29 1994-06-27 Nucleic acids encoding protocadherin
PCT/US1995/008071 WO1996000289A1 (en) 1994-06-27 1995-06-26 Protocadherin proteins and their uses

Publications (1)

Publication Number Publication Date
DE69534588D1 true DE69534588D1 (de) 2005-12-15

Family

ID=23021746

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69534588T Expired - Lifetime DE69534588D1 (de) 1994-06-27 1995-06-26 Protocadherin-proteine und verwendungen davon

Country Status (18)

Country Link
US (5) US5798224A (de)
EP (1) EP0719330B1 (de)
JP (1) JP3560344B2 (de)
CN (1) CN1105187C (de)
AT (1) ATE309347T1 (de)
AU (1) AU699135B2 (de)
BR (1) BR9506058A (de)
CA (1) CA2170156A1 (de)
CZ (1) CZ288789B6 (de)
DE (1) DE69534588D1 (de)
FI (1) FI960888A0 (de)
HU (1) HU221637B1 (de)
MX (1) MX9600666A (de)
NO (1) NO319686B1 (de)
PL (1) PL182324B1 (de)
RU (1) RU2197525C2 (de)
SK (1) SK281413B6 (de)
WO (1) WO1996000289A1 (de)

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AU2582897A (en) * 1996-03-15 1997-10-01 Millennium Pharmaceuticals, Inc. Compositions and methods for the diagnosis, prevention, and treatment of neoplastic cell growth and proliferation
AU5913898A (en) * 1997-01-09 1998-08-03 Genetics Institute Inc. Secreted proteins and polynucleotides encoding them
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO1999029860A1 (en) * 1997-12-08 1999-06-17 Ontogeny, Inc. Cadherin-like polypeptides, methods and compositions related thereto
JP2001526035A (ja) * 1997-12-10 2001-12-18 シーエスエル、リミテッド Ｐｏｒｐｈｏｒｙｍｏｎａｓｇｉｎｇｉｖａｌｉｓポリペプチドおよびヌクレオチド
EP1241185B1 (de) * 1998-03-26 2005-01-05 Genentech, Inc. Nukleinsäure die in menschliche Tumoren vervielfältigt sind, und damit zusammenhängende Materiale und Verfahren
US6472367B1 (en) 1998-05-05 2002-10-29 Adherex Technologies, Inc. Compounds and methods for modulating OB-cadherin mediated cell adhesion
US6638911B1 (en) 1998-05-05 2003-10-28 Adherex Technologies Inc. Compounds and methods for modulating desmosomal cadherin-mediated functions
US6680175B2 (en) * 1998-05-05 2004-01-20 Adherex Technologies, Inc. Methods for diagnosing and evaluating cancer
US20050203025A1 (en) * 1998-05-05 2005-09-15 Adherex Technologies, Inc. Compounds and methods for modulating nonclassical cadherin-mediated functions
US7481999B2 (en) * 1998-05-05 2009-01-27 Adherex Technologies, Inc. Compounds and methods for modulating OB-cadherin-mediated function
US6277824B1 (en) 1998-07-10 2001-08-21 Adherex Technologies Compounds and methods for modulating adhesion molecule function
US20030096951A1 (en) * 1998-08-14 2003-05-22 Kenneth Jacobs Secreted proteins and polynucleotides encoding them
US20030203446A1 (en) 1998-10-07 2003-10-30 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7041807B1 (en) 1999-06-23 2006-05-09 Caprion Pharmaceuticals, Inc. Antibodies to a YYX epitope of a mammalian prion protein
US6787136B1 (en) * 1999-09-03 2004-09-07 The Brigham And Women's Hospital, Inc. Methods and compositions for treatment of inflammatory disease using cadherin-11 modulating agents
CN1313328A (zh) * 2000-03-15 2001-09-19 上海博德基因开发有限公司 一种新的多肽——人原钙粘素14和编码这种多肽的多核苷酸
AU2001275306A1 (en) * 2000-06-06 2001-12-17 Genaissance Pharmaceuticals, Inc. Haplotypes of the pcdh2 gene
US6790636B1 (en) * 2000-06-14 2004-09-14 The United States Of America As Represented By The Department Of Health And Human Services Rapid fluorescent labeling of tissue for microdissection using fluorescent specific binding agents
US7205120B2 (en) * 2000-07-19 2007-04-17 Pharmacia & Upjohn Company Substrates and assays for β-secretase activity
US7122311B2 (en) * 2001-07-16 2006-10-17 Novartis Ag Methods for determining the risk of developing asthma characterized by bronchial hyperresponsiveness
US20040072236A1 (en) * 2002-09-27 2004-04-15 Neil Cashman PrPSc -interacting molecules and uses thereof
CA2506037A1 (en) * 2002-11-14 2004-06-10 Adherex Technologies, Inc. Compounds and methods for modulating desmosomal and atypical cadherin-mediated cell adhesion
CN101492673B (zh) * 2008-01-25 2012-01-11 中国科学院上海生命科学研究院 非洲爪蟾xpapc基因启动子及其组织特异性增强子
CN102274509A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 治疗或预防癌症的药物
CN102274499A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 用于治疗或预防癌症的药物
CN102274490A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 一种用于治疗或预防癌症的药物
CN102274506A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 治疗或预防癌症的药物
CN102274501A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 一种治疗或预防癌症的药物
CN102274503A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 治疗或预防癌症的药物
CN102274507A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 一种用于治疗或预防癌症的药物
CN102274489A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 治疗或预防癌症的药物
NZ595792A (en) * 2009-04-20 2014-01-31 Oxford Biotherapeutics Ltd Antibodies specific to cadherin-17
JPWO2011115268A1 (ja) * 2010-03-18 2013-07-04 大日本住友製薬株式会社 腫瘍血管新生阻害剤
US8877188B2 (en) 2010-05-04 2014-11-04 The Brigham And Women's Hospital, Inc. Detection and treatment of non-dermal fibrosis
US9534058B2 (en) 2012-02-08 2017-01-03 Abbvie Stemcentrx Llc Anti-CD324 monoclonal antibodies and uses thereof
CN103194476A (zh) * 2013-04-07 2013-07-10 新乡医学院 鸡pcdh1基因部分片段的克隆、表达及多克隆抗体的制备
PE20170903A1 (es) * 2014-08-12 2017-07-12 Novartis Ag Conjugados de farmacos con anticuerpos anti-cdh6
WO2016100301A1 (en) 2014-12-15 2016-06-23 The Brigham And Women's Hospital, Inc. Use of cadherin-11 antagonists to treat obesity-associated conditions and other metabolic disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05500504A (ja) * 1989-09-27 1993-02-04 アテナ・ニュウロサイエンスィズ・インコーポレイテッド 細胞付着阻止のための組成物及び使用方法
CA2095115A1 (en) * 1990-10-30 1992-05-01 Barbara Ranscht T-cadherin adhesion molecule

Also Published As

Publication number Publication date
BR9506058A (pt) 1997-08-05
ATE309347T1 (de) 2005-11-15
WO1996000289A1 (en) 1996-01-04
US5891706A (en) 1999-04-06
US5798224A (en) 1998-08-25
EP0719330A1 (de) 1996-07-03
CZ48296A3 (en) 1996-11-13
FI960888A (fi) 1996-02-26
SK281413B6 (sk) 2001-03-12
PL182324B1 (pl) 2001-12-31
NO319686B1 (no) 2005-09-05
RU2197525C2 (ru) 2003-01-27
HU221637B1 (hu) 2002-12-28
JPH09505740A (ja) 1997-06-10
EP0719330B1 (de) 2005-11-09
CA2170156A1 (en) 1996-01-04
CZ288789B6 (cs) 2001-09-12
CN1134172A (zh) 1996-10-23
HUT75825A (en) 1997-05-28
US5708143A (en) 1998-01-13
US6262237B1 (en) 2001-07-17
PL313256A1 (en) 1996-06-24
NO960767D0 (no) 1996-02-26
JP3560344B2 (ja) 2004-09-02
AU2872495A (en) 1996-01-19
HU9600449D0 (en) 1996-04-29
AU699135B2 (en) 1998-11-26
CN1105187C (zh) 2003-04-09
US20030139581A1 (en) 2003-07-24
MX9600666A (es) 1997-06-28
SK25296A3 (en) 1997-02-05
NO960767L (no) 1996-04-26
FI960888A0 (fi) 1996-02-26

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Legal Events

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8332 No legal effect for de