DE69833645T2 - Neue therapeutische kombinationen aus mirtazapin und antipsychotika, zur behandlung oder prophylaxe von psychotischen störungen - Google Patents

Neue therapeutische kombinationen aus mirtazapin und antipsychotika, zur behandlung oder prophylaxe von psychotischen störungen Download PDF

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Publication number
DE69833645T2
DE69833645T2 DE69833645T DE69833645T DE69833645T2 DE 69833645 T2 DE69833645 T2 DE 69833645T2 DE 69833645 T DE69833645 T DE 69833645T DE 69833645 T DE69833645 T DE 69833645T DE 69833645 T2 DE69833645 T2 DE 69833645T2
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DE
Germany
Prior art keywords
mirtazapine
haloperidol
treatment
risperidone
sulpiride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69833645T
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German (de)
English (en)
Other versions
DE69833645D1 (de
Inventor
Louis Christophorus BROEKKAMP
Henricus Hermanus BERENDSEN
Martin Roger PINDER
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Organon NV
Original Assignee
Akzo Nobel NV
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Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of DE69833645D1 publication Critical patent/DE69833645D1/de
Application granted granted Critical
Publication of DE69833645T2 publication Critical patent/DE69833645T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69833645T 1997-03-27 1998-03-25 Neue therapeutische kombinationen aus mirtazapin und antipsychotika, zur behandlung oder prophylaxe von psychotischen störungen Expired - Lifetime DE69833645T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP97200881 1997-03-27
EP97200881 1997-03-27
EP97202785 1997-09-11
EP97202785 1997-09-11
PCT/EP1998/001920 WO1998043646A1 (en) 1997-03-27 1998-03-25 New therapeutic combinations of mirtazapine and antipsychotic agents, for the treatment or prophylaxis of psychotic disorders

Publications (2)

Publication Number Publication Date
DE69833645D1 DE69833645D1 (de) 2006-04-27
DE69833645T2 true DE69833645T2 (de) 2006-08-24

Family

ID=26146283

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69833645T Expired - Lifetime DE69833645T2 (de) 1997-03-27 1998-03-25 Neue therapeutische kombinationen aus mirtazapin und antipsychotika, zur behandlung oder prophylaxe von psychotischen störungen

Country Status (24)

Country Link
EP (1) EP0969845B1 (OSRAM)
JP (2) JP4377456B2 (OSRAM)
KR (1) KR100577865B1 (OSRAM)
CN (1) CN1226036C (OSRAM)
AR (1) AR012193A1 (OSRAM)
AT (1) ATE318604T1 (OSRAM)
AU (1) AU726194B2 (OSRAM)
BR (1) BR9808077A (OSRAM)
CA (1) CA2284551C (OSRAM)
CZ (1) CZ298105B6 (OSRAM)
DE (1) DE69833645T2 (OSRAM)
DK (1) DK0969845T3 (OSRAM)
ES (1) ES2259207T3 (OSRAM)
HU (1) HUP0002742A3 (OSRAM)
ID (1) ID22283A (OSRAM)
IL (1) IL123716A (OSRAM)
NO (1) NO994673L (OSRAM)
NZ (1) NZ337618A (OSRAM)
PL (1) PL191449B1 (OSRAM)
PT (1) PT969845E (OSRAM)
RU (1) RU2222330C2 (OSRAM)
TR (1) TR199902334T2 (OSRAM)
TW (1) TW587938B (OSRAM)
WO (1) WO1998043646A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012011839A1 (de) * 2012-06-14 2013-12-19 Norbert Müller Verwendung von Interferon-gamma in einem Verfahren zur Behandlung von psychiatrischen Erkrankungen

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL121076A (en) * 1996-06-19 2000-10-31 Akzo Nobel Nv Pharmaceutical combinations comprising mirtazapine and one or more selective serotonin reuptake inhibitors
US6280763B1 (en) 1999-05-10 2001-08-28 Pierce Management, Llc Apparatus and method for transdermal delivery of bupropion
FR2797399B1 (fr) * 1999-08-13 2002-10-18 Aventis Pharma Sa Utilisation de la cyamemazine dans le traitement du sevrage aux benzodiazepines
US6350773B1 (en) 1999-12-10 2002-02-26 American Home Products Corporation Therapeutic combinations of (S)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro 7H-1,4-dioxino{2,3-e}indol-8-one and neuroleptics for the treatment or prevention of psychotic disorders
FR2802101B1 (fr) 1999-12-10 2003-02-28 Aventis Pharma Sa Association de cymemazine et d'un neuroleptique atypique
CA2396066A1 (en) 2000-01-19 2001-07-26 Akzo Nobel N.V. Drug combination for the treatment of depression and related disorders comprising mirtazapine and gepirone
US6495154B1 (en) * 2000-11-21 2002-12-17 Vivus Inc. On demand administration of clomipramine and salts thereof to treat premature ejaculation
EP1795199A3 (en) * 2001-02-06 2007-07-25 AstraZeneca AB Quetiapine for the treatment of substance dependence or substance abuse
ES2284830T3 (es) 2001-02-06 2007-11-16 Astrazeneca Ab Uso de quetiapina para el tratamiento de la cocaina.
RU2232574C2 (ru) * 2002-04-05 2004-07-20 Новосибирский институт органической химии им. Н.Н.Ворожцова СО РАН Лекарственное средство для лечения различных форм депрессий "флуоглизин"
WO2005044262A1 (en) 2003-10-29 2005-05-19 Wyeth Sustained release pharmaceutical compositions comprising aplindore and derivatives thereof
EP1547650A1 (en) * 2003-12-02 2005-06-29 B & B Beheer NV Use of D4 and 5-HT2A antagonists, inverse agonists or partial agonists
WO2005053796A1 (en) * 2003-12-02 2005-06-16 B & B Beheer Nv Use of d4 and 5-ht2a antagonists, inverse agonists or partial agonists
US7884096B2 (en) 2003-12-02 2011-02-08 Pharmaneuroboost N.V. Method of treating mental disorders using of D4 and 5-HT2A antagonists, inverse agonists or partial agonists
SI1541197T1 (sl) * 2003-12-02 2009-08-31 Pharmaneuroboost N V Uporaba pipamperona in sndri, snri ali ssri za zdravljenje razpoloĺ˝enjskih ali tesnobnih motenj
US7855195B2 (en) 2003-12-02 2010-12-21 Pharmaneuroboost N.V. Method of treating mental disorders using D4 and 5-HT2A antagonists, inverse agonists or partial agonists
RU2006146612A (ru) 2004-06-03 2008-07-20 Ф.Хоффманн-Ля Рош Аг (Ch) Лечение цисплатином и ингибитором рецептора эпидермального фактора роста (egfr)
AU2007255724B2 (en) * 2006-06-09 2012-05-10 Dainippon Sumitomo Pharma Co., Ltd. Novel tape preparation
JOP20120083B1 (ar) * 2011-04-05 2021-08-17 Otsuka Pharma Co Ltd توليفات تشتمل على بريكس ببرازول أو ملح منه وعقار ثاني للاستخدام في علاج اضطراب cns
RU2509560C1 (ru) * 2013-03-22 2014-03-20 Общество С Ограниченной Ответственностью "Валента-Интеллект" Новые терапевтические комбинации миртазапина для применения при болевых расстройствах

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2410821A1 (de) * 1974-03-07 1975-09-18 Hoechst Ag Pharmazeutische kombinationspraeparate mit psychotroper wirkung und verfahren zu ihrer herstellung
CA1327008C (en) * 1988-01-15 1994-02-15 Walter Merz Anti-psychotic imidazobenzodiazepine
DK0431663T3 (da) * 1989-12-06 1994-03-07 Akzo Nobel Nv Stabiliserende opløsninger af psykotrope midler
FI111367B (fi) * 1991-02-04 2003-07-15 Aventis Pharma Inc Menetelmä terapeuttisesti käyttökelpoisten N-(aryylioksialkyyli)heteroaryyli-8-atsabisyklo[3.2.1]oktaanijohdannaisten valmistamiseksi ja menetelmässä käytetyt välituotteet
ZA935078B (en) * 1992-07-15 1994-02-07 Nicolaas Johannes Jaco Loetter Pharmaceutical composition
RU2062114C1 (ru) * 1992-09-30 1996-06-20 Московский научно-исследовательский институт психиатрии МЗ РФ Способ лечения эндогенных психозов
ATE188375T1 (de) * 1992-11-17 2000-01-15 Yoshitomi Pharmaceutical Ein antipsychotikum enthaltende mikrokugel zur verzögerten freisetzung und verfahren für ihre herstellung
JPH07242669A (ja) * 1994-03-07 1995-09-19 Akikazu Ogawa 四環系とブチロフェノン誘導体を化学結合した化合物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012011839A1 (de) * 2012-06-14 2013-12-19 Norbert Müller Verwendung von Interferon-gamma in einem Verfahren zur Behandlung von psychiatrischen Erkrankungen
DE102012011839B4 (de) 2012-06-14 2018-03-22 Norbert Müller Verwendung von Interferon-gamma in einem Verfahren zur Behandlung von psychiatrischen Erkrankungen

Also Published As

Publication number Publication date
ATE318604T1 (de) 2006-03-15
TR199902334T2 (xx) 2000-01-21
CZ343199A3 (cs) 2000-04-12
CN1226036C (zh) 2005-11-09
AU7213998A (en) 1998-10-22
JP5023315B2 (ja) 2012-09-12
DE69833645D1 (de) 2006-04-27
PT969845E (pt) 2006-05-31
HUP0002742A3 (en) 2003-03-28
JP2009280596A (ja) 2009-12-03
HK1023293A1 (en) 2000-09-08
PL191449B1 (pl) 2006-05-31
NO994673L (no) 1999-11-17
ID22283A (id) 1999-09-30
NO994673D0 (no) 1999-09-24
CZ298105B6 (cs) 2007-06-27
RU2222330C2 (ru) 2004-01-27
EP0969845A1 (en) 2000-01-12
NZ337618A (en) 2000-06-23
TW587938B (en) 2004-05-21
HUP0002742A2 (hu) 2001-05-28
KR100577865B1 (ko) 2006-05-10
CN1251526A (zh) 2000-04-26
CA2284551A1 (en) 1998-10-08
IL123716A0 (en) 1998-12-06
CA2284551C (en) 2007-06-12
BR9808077A (pt) 2000-03-08
JP2001521497A (ja) 2001-11-06
AR012193A1 (es) 2000-09-27
DK0969845T3 (da) 2006-06-19
PL335890A1 (en) 2000-05-22
WO1998043646A1 (en) 1998-10-08
JP4377456B2 (ja) 2009-12-02
AU726194B2 (en) 2000-11-02
KR20010005677A (ko) 2001-01-15
EP0969845B1 (en) 2006-03-01
IL123716A (en) 2001-03-19
ES2259207T3 (es) 2006-09-16

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