RU2222330C2 - Новые терапевтические комбинации миртазапина и антипсихотических средств для лечения или профилактики психотических расстройств - Google Patents

Новые терапевтические комбинации миртазапина и антипсихотических средств для лечения или профилактики психотических расстройств Download PDF

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Publication number
RU2222330C2
RU2222330C2 RU99122597/14A RU99122597A RU2222330C2 RU 2222330 C2 RU2222330 C2 RU 2222330C2 RU 99122597/14 A RU99122597/14 A RU 99122597/14A RU 99122597 A RU99122597 A RU 99122597A RU 2222330 C2 RU2222330 C2 RU 2222330C2
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Prior art keywords
mirtazapine
antipsychotic
antipsychotic agent
combination
pharmaceutical composition
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RU99122597/14A
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English (en)
Russian (ru)
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RU99122597A (ru
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Христофорус Луи Эдуард БРУККАМП (NL)
Христофорус Луи Эдуард БРУККАМП
Херманус Хенрикус Герардус БЕРЕНДСЕН (NL)
Херманус Хенрикус Герардус БЕРЕНДСЕН
Роджер Мартин ПИНДЕР (NL)
Роджер Мартин ПИНДЕР
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Акцо Нобель Н.В.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU99122597/14A 1997-03-27 1998-03-25 Новые терапевтические комбинации миртазапина и антипсихотических средств для лечения или профилактики психотических расстройств RU2222330C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP97200881 1997-03-27
EP97200881.7 1997-03-27
EP97202785 1997-09-11
EP97202785.8 1997-09-11

Publications (2)

Publication Number Publication Date
RU99122597A RU99122597A (ru) 2001-09-10
RU2222330C2 true RU2222330C2 (ru) 2004-01-27

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RU99122597/14A RU2222330C2 (ru) 1997-03-27 1998-03-25 Новые терапевтические комбинации миртазапина и антипсихотических средств для лечения или профилактики психотических расстройств

Country Status (24)

Country Link
EP (1) EP0969845B1 (OSRAM)
JP (2) JP4377456B2 (OSRAM)
KR (1) KR100577865B1 (OSRAM)
CN (1) CN1226036C (OSRAM)
AR (1) AR012193A1 (OSRAM)
AT (1) ATE318604T1 (OSRAM)
AU (1) AU726194B2 (OSRAM)
BR (1) BR9808077A (OSRAM)
CA (1) CA2284551C (OSRAM)
CZ (1) CZ298105B6 (OSRAM)
DE (1) DE69833645T2 (OSRAM)
DK (1) DK0969845T3 (OSRAM)
ES (1) ES2259207T3 (OSRAM)
HU (1) HUP0002742A3 (OSRAM)
ID (1) ID22283A (OSRAM)
IL (1) IL123716A (OSRAM)
NO (1) NO994673L (OSRAM)
NZ (1) NZ337618A (OSRAM)
PL (1) PL191449B1 (OSRAM)
PT (1) PT969845E (OSRAM)
RU (1) RU2222330C2 (OSRAM)
TR (1) TR199902334T2 (OSRAM)
TW (1) TW587938B (OSRAM)
WO (1) WO1998043646A1 (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2445959C2 (ru) * 2006-06-09 2012-03-27 ДАЙНИППОН СУМИТОМО ФАРМА Ко., ЛТД. Новый лейкопластырный препарат
RU2509560C1 (ru) * 2013-03-22 2014-03-20 Общество С Ограниченной Ответственностью "Валента-Интеллект" Новые терапевтические комбинации миртазапина для применения при болевых расстройствах

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IL121076A (en) * 1996-06-19 2000-10-31 Akzo Nobel Nv Pharmaceutical combinations comprising mirtazapine and one or more selective serotonin reuptake inhibitors
US6280763B1 (en) 1999-05-10 2001-08-28 Pierce Management, Llc Apparatus and method for transdermal delivery of bupropion
FR2797399B1 (fr) * 1999-08-13 2002-10-18 Aventis Pharma Sa Utilisation de la cyamemazine dans le traitement du sevrage aux benzodiazepines
US6350773B1 (en) 1999-12-10 2002-02-26 American Home Products Corporation Therapeutic combinations of (S)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro 7H-1,4-dioxino{2,3-e}indol-8-one and neuroleptics for the treatment or prevention of psychotic disorders
FR2802101B1 (fr) 1999-12-10 2003-02-28 Aventis Pharma Sa Association de cymemazine et d'un neuroleptique atypique
CA2396066A1 (en) 2000-01-19 2001-07-26 Akzo Nobel N.V. Drug combination for the treatment of depression and related disorders comprising mirtazapine and gepirone
US6495154B1 (en) * 2000-11-21 2002-12-17 Vivus Inc. On demand administration of clomipramine and salts thereof to treat premature ejaculation
EP1795199A3 (en) * 2001-02-06 2007-07-25 AstraZeneca AB Quetiapine for the treatment of substance dependence or substance abuse
ES2284830T3 (es) 2001-02-06 2007-11-16 Astrazeneca Ab Uso de quetiapina para el tratamiento de la cocaina.
RU2232574C2 (ru) * 2002-04-05 2004-07-20 Новосибирский институт органической химии им. Н.Н.Ворожцова СО РАН Лекарственное средство для лечения различных форм депрессий "флуоглизин"
WO2005044262A1 (en) 2003-10-29 2005-05-19 Wyeth Sustained release pharmaceutical compositions comprising aplindore and derivatives thereof
EP1547650A1 (en) * 2003-12-02 2005-06-29 B & B Beheer NV Use of D4 and 5-HT2A antagonists, inverse agonists or partial agonists
WO2005053796A1 (en) * 2003-12-02 2005-06-16 B & B Beheer Nv Use of d4 and 5-ht2a antagonists, inverse agonists or partial agonists
US7884096B2 (en) 2003-12-02 2011-02-08 Pharmaneuroboost N.V. Method of treating mental disorders using of D4 and 5-HT2A antagonists, inverse agonists or partial agonists
SI1541197T1 (sl) * 2003-12-02 2009-08-31 Pharmaneuroboost N V Uporaba pipamperona in sndri, snri ali ssri za zdravljenje razpoloĺ˝enjskih ali tesnobnih motenj
US7855195B2 (en) 2003-12-02 2010-12-21 Pharmaneuroboost N.V. Method of treating mental disorders using D4 and 5-HT2A antagonists, inverse agonists or partial agonists
RU2006146612A (ru) 2004-06-03 2008-07-20 Ф.Хоффманн-Ля Рош Аг (Ch) Лечение цисплатином и ингибитором рецептора эпидермального фактора роста (egfr)
JOP20120083B1 (ar) * 2011-04-05 2021-08-17 Otsuka Pharma Co Ltd توليفات تشتمل على بريكس ببرازول أو ملح منه وعقار ثاني للاستخدام في علاج اضطراب cns
DE102012011839B4 (de) * 2012-06-14 2018-03-22 Norbert Müller Verwendung von Interferon-gamma in einem Verfahren zur Behandlung von psychiatrischen Erkrankungen

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RU2062114C1 (ru) * 1992-09-30 1996-06-20 Московский научно-исследовательский институт психиатрии МЗ РФ Способ лечения эндогенных психозов
RU2075479C1 (ru) * 1991-02-04 1997-03-20 Хехст-Рассел Фармасьютикалз Инкорпорейтед Арилоксиалкилгетероарил-8-азабицикло(3,2,1)октаны, способ их получения и гетероарил-8-азабицикло(3,2,1)октаны

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DE2410821A1 (de) * 1974-03-07 1975-09-18 Hoechst Ag Pharmazeutische kombinationspraeparate mit psychotroper wirkung und verfahren zu ihrer herstellung
CA1327008C (en) * 1988-01-15 1994-02-15 Walter Merz Anti-psychotic imidazobenzodiazepine
DK0431663T3 (da) * 1989-12-06 1994-03-07 Akzo Nobel Nv Stabiliserende opløsninger af psykotrope midler
ZA935078B (en) * 1992-07-15 1994-02-07 Nicolaas Johannes Jaco Loetter Pharmaceutical composition
ATE188375T1 (de) * 1992-11-17 2000-01-15 Yoshitomi Pharmaceutical Ein antipsychotikum enthaltende mikrokugel zur verzögerten freisetzung und verfahren für ihre herstellung
JPH07242669A (ja) * 1994-03-07 1995-09-19 Akikazu Ogawa 四環系とブチロフェノン誘導体を化学結合した化合物

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RU2075479C1 (ru) * 1991-02-04 1997-03-20 Хехст-Рассел Фармасьютикалз Инкорпорейтед Арилоксиалкилгетероарил-8-азабицикло(3,2,1)октаны, способ их получения и гетероарил-8-азабицикло(3,2,1)октаны
RU2062114C1 (ru) * 1992-09-30 1996-06-20 Московский научно-исследовательский институт психиатрии МЗ РФ Способ лечения эндогенных психозов

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WOLFERSDORF M., et. al. "Paroxetinc as antidepressant in combined antidepressant - neuroleotic therapy in delusional depression: observation of clinical use", Pharmacopsychiatry, 1995, Mar; 28(2): 56-60. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2445959C2 (ru) * 2006-06-09 2012-03-27 ДАЙНИППОН СУМИТОМО ФАРМА Ко., ЛТД. Новый лейкопластырный препарат
RU2509560C1 (ru) * 2013-03-22 2014-03-20 Общество С Ограниченной Ответственностью "Валента-Интеллект" Новые терапевтические комбинации миртазапина для применения при болевых расстройствах

Also Published As

Publication number Publication date
ATE318604T1 (de) 2006-03-15
TR199902334T2 (xx) 2000-01-21
CZ343199A3 (cs) 2000-04-12
CN1226036C (zh) 2005-11-09
AU7213998A (en) 1998-10-22
JP5023315B2 (ja) 2012-09-12
DE69833645D1 (de) 2006-04-27
DE69833645T2 (de) 2006-08-24
PT969845E (pt) 2006-05-31
HUP0002742A3 (en) 2003-03-28
JP2009280596A (ja) 2009-12-03
HK1023293A1 (en) 2000-09-08
PL191449B1 (pl) 2006-05-31
NO994673L (no) 1999-11-17
ID22283A (id) 1999-09-30
NO994673D0 (no) 1999-09-24
CZ298105B6 (cs) 2007-06-27
EP0969845A1 (en) 2000-01-12
NZ337618A (en) 2000-06-23
TW587938B (en) 2004-05-21
HUP0002742A2 (hu) 2001-05-28
KR100577865B1 (ko) 2006-05-10
CN1251526A (zh) 2000-04-26
CA2284551A1 (en) 1998-10-08
IL123716A0 (en) 1998-12-06
CA2284551C (en) 2007-06-12
BR9808077A (pt) 2000-03-08
JP2001521497A (ja) 2001-11-06
AR012193A1 (es) 2000-09-27
DK0969845T3 (da) 2006-06-19
PL335890A1 (en) 2000-05-22
WO1998043646A1 (en) 1998-10-08
JP4377456B2 (ja) 2009-12-02
AU726194B2 (en) 2000-11-02
KR20010005677A (ko) 2001-01-15
EP0969845B1 (en) 2006-03-01
IL123716A (en) 2001-03-19
ES2259207T3 (es) 2006-09-16

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Effective date: 20070417

MM4A The patent is invalid due to non-payment of fees

Effective date: 20090326