DE69818458T3 - Ribosom-komplexe als selektionspartikel für die in vitro anzeige und evolution von proteinen - Google Patents

Ribosom-komplexe als selektionspartikel für die in vitro anzeige und evolution von proteinen Download PDF

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Publication number
DE69818458T3
DE69818458T3 DE69818458T DE69818458T DE69818458T3 DE 69818458 T3 DE69818458 T3 DE 69818458T3 DE 69818458 T DE69818458 T DE 69818458T DE 69818458 T DE69818458 T DE 69818458T DE 69818458 T3 DE69818458 T3 DE 69818458T3
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DE
Germany
Prior art keywords
mrna
protein
peptide
dna
pcr
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE69818458T
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German (de)
English (en)
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DE69818458D1 (de
DE69818458T2 (de
Inventor
John Michael TAUSSIG
Mingyue He
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Crescendo Biologics Ltd
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Crescendo Biologics Ltd
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Priority claimed from GBGB9710829.4A external-priority patent/GB9710829D0/en
Priority claimed from GBGB9724850.4A external-priority patent/GB9724850D0/en
Priority claimed from GBGB9804195.7A external-priority patent/GB9804195D0/en
Application filed by Crescendo Biologics Ltd filed Critical Crescendo Biologics Ltd
Publication of DE69818458D1 publication Critical patent/DE69818458D1/de
Publication of DE69818458T2 publication Critical patent/DE69818458T2/de
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Publication of DE69818458T3 publication Critical patent/DE69818458T3/de
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1041Ribosome/Polysome display, e.g. SPERT, ARM
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE69818458T 1997-05-28 1998-05-28 Ribosom-komplexe als selektionspartikel für die in vitro anzeige und evolution von proteinen Expired - Lifetime DE69818458T3 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB9710829 1997-05-28
GBGB9710829.4A GB9710829D0 (en) 1997-05-28 1997-05-28 Selection particles for in vitro display and evolution of antibody combining sites
GBGB9724850.4A GB9724850D0 (en) 1997-11-26 1997-11-26 Selection particles for in vitro display and evolution of antibody combining sites
GB9724850 1997-11-26
GBGB9804195.7A GB9804195D0 (en) 1998-02-28 1998-02-28 Selection particles for in vitro display and evolution of antibody combining sites
GB9804195 1998-02-28
PCT/GB1998/001564 WO1998054312A1 (en) 1997-05-28 1998-05-28 Ribosome complexes as selection particles for in vitro display and evolution of proteins

Publications (3)

Publication Number Publication Date
DE69818458D1 DE69818458D1 (de) 2003-10-30
DE69818458T2 DE69818458T2 (de) 2004-07-08
DE69818458T3 true DE69818458T3 (de) 2009-12-17

Family

ID=27268863

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69818458T Expired - Lifetime DE69818458T3 (de) 1997-05-28 1998-05-28 Ribosom-komplexe als selektionspartikel für die in vitro anzeige und evolution von proteinen

Country Status (10)

Country Link
US (1) US6620587B1 (https=)
EP (1) EP0985032B2 (https=)
JP (1) JP4060892B2 (https=)
AT (1) ATE250668T1 (https=)
CA (1) CA2291721C (https=)
DE (1) DE69818458T3 (https=)
DK (1) DK0985032T4 (https=)
ES (1) ES2209145T5 (https=)
PT (1) PT985032E (https=)
WO (1) WO1998054312A1 (https=)

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Also Published As

Publication number Publication date
ES2209145T5 (es) 2009-10-30
AU725957B2 (en) 2000-10-26
DK0985032T4 (da) 2009-08-31
JP4060892B2 (ja) 2008-03-12
CA2291721A1 (en) 1998-12-03
US6620587B1 (en) 2003-09-16
WO1998054312A1 (en) 1998-12-03
DE69818458D1 (de) 2003-10-30
DK0985032T3 (da) 2004-02-02
DE69818458T2 (de) 2004-07-08
EP0985032B2 (en) 2009-06-03
JP2002500514A (ja) 2002-01-08
ATE250668T1 (de) 2003-10-15
EP0985032B1 (en) 2003-09-24
AU7666698A (en) 1998-12-30
EP0985032A1 (en) 2000-03-15
CA2291721C (en) 2011-08-09
PT985032E (pt) 2004-02-27
ES2209145T3 (es) 2004-06-16

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: CRESCENDO BIOLOGICS LTD., BABRAHAM, CAMBRIDGE, GB

8328 Change in the person/name/address of the agent

Representative=s name: MARKS & CLERK (LUXEMBOURG) LLP, LUXEMBOURG, LU