JP4060892B2 - タンパク質のin vitroディスプレイ及び進化のための選択粒子としてのリボソーム複合体 - Google Patents
タンパク質のin vitroディスプレイ及び進化のための選択粒子としてのリボソーム複合体 Download PDFInfo
- Publication number
- JP4060892B2 JP4060892B2 JP50038699A JP50038699A JP4060892B2 JP 4060892 B2 JP4060892 B2 JP 4060892B2 JP 50038699 A JP50038699 A JP 50038699A JP 50038699 A JP50038699 A JP 50038699A JP 4060892 B2 JP4060892 B2 JP 4060892B2
- Authority
- JP
- Japan
- Prior art keywords
- mrna
- protein
- dna
- peptide
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1041—Ribosome/Polysome display, e.g. SPERT, ARM
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9710829.4A GB9710829D0 (en) | 1997-05-28 | 1997-05-28 | Selection particles for in vitro display and evolution of antibody combining sites |
| GBGB9724850.4A GB9724850D0 (en) | 1997-11-26 | 1997-11-26 | Selection particles for in vitro display and evolution of antibody combining sites |
| GB9804195.7 | 1998-02-28 | ||
| GB9724850.4 | 1998-02-28 | ||
| GB9710829.4 | 1998-02-28 | ||
| GBGB9804195.7A GB9804195D0 (en) | 1998-02-28 | 1998-02-28 | Selection particles for in vitro display and evolution of antibody combining sites |
| PCT/GB1998/001564 WO1998054312A1 (en) | 1997-05-28 | 1998-05-28 | Ribosome complexes as selection particles for in vitro display and evolution of proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002500514A JP2002500514A (ja) | 2002-01-08 |
| JP2002500514A5 JP2002500514A5 (https=) | 2005-12-08 |
| JP4060892B2 true JP4060892B2 (ja) | 2008-03-12 |
Family
ID=27268863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50038699A Expired - Fee Related JP4060892B2 (ja) | 1997-05-28 | 1998-05-28 | タンパク質のin vitroディスプレイ及び進化のための選択粒子としてのリボソーム複合体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6620587B1 (https=) |
| EP (1) | EP0985032B2 (https=) |
| JP (1) | JP4060892B2 (https=) |
| AT (1) | ATE250668T1 (https=) |
| CA (1) | CA2291721C (https=) |
| DE (1) | DE69818458T3 (https=) |
| DK (1) | DK0985032T4 (https=) |
| ES (1) | ES2209145T5 (https=) |
| PT (1) | PT985032E (https=) |
| WO (1) | WO1998054312A1 (https=) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4854999A (en) * | 1998-07-02 | 2000-01-24 | Invitro Diagnostics, Inc. | Methods, compositions and apparatus for making nucleic acid molecules having a selected affinity to a target molecule |
| DE19932688B4 (de) | 1999-07-13 | 2009-10-08 | Scil Proteins Gmbh | Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen |
| GB9917027D0 (en) * | 1999-07-20 | 1999-09-22 | Affibody Technology Sweeden Ab | In vitro selection and optional identification of polypeptides using solid support carriers |
| IL150291A0 (en) | 2000-01-11 | 2002-12-01 | Maxygen Inc | Integrated systems and methods for diversity generation and screening |
| EP1652919A1 (en) * | 2000-03-31 | 2006-05-03 | Cambridge Antibody Technology LTD | Improvements to ribosome display |
| ES2253358T3 (es) * | 2000-03-31 | 2006-06-01 | Cambridge Antibody Technology Limited | Mejoras en la visualizacion del ribosoma. |
| US7129326B2 (en) | 2000-04-14 | 2006-10-31 | Genencor International, Inc. | Methods for selective targeting |
| DK1360500T3 (da) | 2000-04-14 | 2010-05-25 | Genencor Int | Fremgangsmåde til selektiv målretning |
| CA2440649A1 (en) | 2001-03-07 | 2002-09-19 | Children's Medical Center Corporation | Method to screen peptide display libraries using minicell display |
| US20060234231A1 (en) * | 2001-06-20 | 2006-10-19 | Nuevolution A/S | Microarrays displaying encoded molecules |
| EP1401850A1 (en) | 2001-06-20 | 2004-03-31 | Nuevolution A/S | Nucleoside derivatives for library preparation |
| DE10145226A1 (de) * | 2001-09-13 | 2003-04-10 | Lifebits Ag | Herstellung von trägergebundenen Molekülen |
| DE10147074A1 (de) * | 2001-09-25 | 2003-05-08 | Beru Ag | Verfahren zum Betreiben einer aus mehreren Heizelementen bestehenden mehrstufigen elektrischen Heizung |
| DE20200926U1 (de) * | 2002-01-23 | 2002-04-18 | Hegenscheidt-MFD GmbH & Co. KG, 41812 Erkelenz | Festwalzgerät einer Festwalzmaschine für Kurbelwellen |
| EP1487978B1 (en) * | 2002-03-15 | 2008-11-19 | Nuevolution A/S | An improved method for synthesising templated molecules |
| US20050221318A1 (en) * | 2002-03-15 | 2005-10-06 | Gouliaev Alex H | Building block forming a c-c bond upon reaction |
| AU2003214033A1 (en) * | 2002-03-15 | 2003-09-29 | Nuevolution A/S | A building block capable of transferring a functional entity |
| AU2003218629A1 (en) * | 2002-03-15 | 2003-09-29 | Nuevolution A/S | A building block forming a c-c or a c-hetero atom bond uponreaction |
| WO2004013070A2 (en) * | 2002-08-01 | 2004-02-12 | Nuevolution A/S | Multi-step synthesis of templated molecules |
| JP4664677B2 (ja) * | 2002-09-06 | 2011-04-06 | イソゲニカ リミテッド | イン・ビトロでのペプチド発現ライブラリー |
| PT2348125T (pt) | 2002-10-30 | 2017-08-29 | Nuevolution As | Método para a síntese de um complexo bifuncional |
| EP2581383A1 (en) | 2002-11-25 | 2013-04-17 | Genencor International, Inc. | Skin or hair binding peptides |
| AU2003291964A1 (en) * | 2002-12-19 | 2004-07-14 | Nuevolution A/S | Quasirandom structure and function guided synthesis methods |
| EP1597394A2 (en) * | 2003-02-21 | 2005-11-23 | Nuevolution A/S | A method for obtaining structural information about an encoded molecule |
| US20070026397A1 (en) * | 2003-02-21 | 2007-02-01 | Nuevolution A/S | Method for producing second-generation library |
| ES2326649T3 (es) * | 2003-03-19 | 2009-10-16 | Crescendo Biologics Ltd. | Recuperacion de dna. |
| DE602004019764D1 (de) * | 2003-03-20 | 2009-04-16 | Nuevolution As | Ligationsvermittelnde codierung von kleinen molekülen |
| DE10324447A1 (de) | 2003-05-28 | 2004-12-30 | Scil Proteins Gmbh | Generierung künstlicher Bindungsproteine auf der Grundlage von Ubiquitin |
| GB0316314D0 (en) * | 2003-07-12 | 2003-08-13 | Univ Belfast | Method |
| EP1670939B1 (en) * | 2003-09-18 | 2009-11-04 | Nuevolution A/S | A method for obtaining structural information concerning an encoded molecule and method for selecting compounds |
| EP1723255B1 (en) * | 2004-02-17 | 2010-12-29 | Nuevolution A/S | Method for enrichment involving elimination by mismatch hybridisation |
| DE602005017370D1 (de) * | 2004-03-22 | 2009-12-10 | Nuevolution As | Ligationscodierung unter verwendung von oligonukleotidbausteinen |
| US20050250112A1 (en) * | 2004-05-07 | 2005-11-10 | Padmabandu Gothami A | Nucleic acids, compositions, methods, and kits for detecting mycoplasma and acholeplasma species |
| US9006393B1 (en) | 2004-08-26 | 2015-04-14 | Patricia L. Clark | Molecular constructs and uses thereof in ribosomal translational events |
| DE102004049479A1 (de) | 2004-10-11 | 2006-04-13 | Scil Proteins Gmbh | Proteinkonjugate zur Verwendung in Therapie, Diagnose und Chromatographie |
| HUE056836T2 (hu) | 2005-12-01 | 2022-03-28 | Nuevolution As | Enzimatikus kódolási eljárások nagy könyvtárak hatékony szintéziséhez |
| GB0605584D0 (en) | 2006-03-20 | 2006-04-26 | Olink Ab | Method for analyte detection using proximity probes |
| US7879974B2 (en) * | 2006-06-29 | 2011-02-01 | The Invention Science Fund I, Llc | Methods for arbitrary peptide synthesis |
| US7879975B2 (en) * | 2006-06-29 | 2011-02-01 | The Invention Science Fund I, Llc | Methods for arbitrary peptide synthesis |
| US7923533B2 (en) * | 2006-06-29 | 2011-04-12 | The Invention Science Fund I, Llc | Methods for arbitrary peptide synthesis |
| US7910695B2 (en) | 2006-06-29 | 2011-03-22 | The Invention Science Fund I, Llc | Methods for arbitrary peptide synthesis |
| US7777002B2 (en) * | 2006-06-29 | 2010-08-17 | The Invention Science Fund I, Llc | Methods for arbitrary peptide synthesis |
| EP1925664A1 (en) | 2006-11-15 | 2008-05-28 | Scil proteins GmbH | Artificial binding proteins based on a modified alpha helical region of ubiquitin |
| US8865179B2 (en) * | 2008-01-26 | 2014-10-21 | Swey-Shen Alexchen | Aptameric IgE peptides in a protein scaffold as an allergy vaccine |
| EP3629022A1 (en) | 2008-07-25 | 2020-04-01 | Richard W. Wagner | Protein screening methods |
| MX2011003381A (es) * | 2008-09-30 | 2011-04-21 | Abbott Lab | Metodo mejorado para despliegue de arn. |
| AU2010332932B2 (en) | 2009-12-14 | 2013-01-17 | Navigo Proteins Gmbh | Modified ubiquitin proteins having a specific binding activity for the extradomain B of fibronectin |
| WO2011111832A1 (ja) | 2010-03-11 | 2011-09-15 | 独立行政法人理化学研究所 | ポリペプチド配列の選択方法、並びに金属酸化物または含珪素化合物結合ペプチドおよびその利用 |
| GB201004292D0 (en) | 2010-03-15 | 2010-04-28 | Olink Ab | Assay for localised detection of analytes |
| WO2011127933A1 (en) | 2010-04-16 | 2011-10-20 | Nuevolution A/S | Bi-functional complexes and methods for making and using such complexes |
| GB201011971D0 (en) | 2010-07-15 | 2010-09-01 | Olink Ab | Methods and product |
| EP2627781B1 (en) | 2010-10-15 | 2017-02-22 | Olink Bioscience AB | Dynamic range methods |
| EP2466310A1 (en) | 2010-12-17 | 2012-06-20 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH | Means and methods for detecting double-strand breaks |
| DE102010056289A1 (de) | 2010-12-24 | 2012-06-28 | Geneart Ag | Verfahren zur Herstellung von Leseraster-korrekten Fragment-Bibliotheken |
| GB201101621D0 (en) | 2011-01-31 | 2011-03-16 | Olink Ab | Method and product |
| JP5948673B2 (ja) | 2011-03-10 | 2016-07-06 | ジーンフロンティア株式会社 | リポ多糖混入量を低減した蛋白質合成用組成物、該組成物を用いた蛋白質製造方法 |
| GB201107863D0 (en) | 2011-05-11 | 2011-06-22 | Olink Ab | Method and product |
| WO2012161227A1 (ja) | 2011-05-23 | 2012-11-29 | 独立行政法人理化学研究所 | 核酸構築物、核酸-蛋白質複合体、及びその利用 |
| JP6146821B2 (ja) | 2011-06-15 | 2017-06-14 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングNavigo Proteins GmbH | 修飾ユビキチンに基づく二量体型結合タンパク質 |
| GB201201547D0 (en) | 2012-01-30 | 2012-03-14 | Olink Ab | Method and product |
| US10421958B2 (en) | 2014-02-05 | 2019-09-24 | Molecular Templates, Inc. | Methods of screening, selecting, and identifying cytotoxic recombinant polypeptides based on an interim diminution of ribotoxicity |
| US20170306039A1 (en) * | 2014-10-22 | 2017-10-26 | Crescendo Biologics Limited | Human vh domain scaffolds |
| JP6738340B2 (ja) | 2015-02-06 | 2020-08-12 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングNavigo Proteins GmbH | 新規なegfr結合タンパク質 |
| AU2016293063B2 (en) | 2015-07-16 | 2018-11-08 | Navigo Proteins Gmbh | Novel immunoglobulin-binding proteins and their use in affinity purification |
| JP2018520675A (ja) | 2015-07-20 | 2018-08-02 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングNavigo Proteins GmbH | ジユビキチン変異タンパク質をベースとした新規結合タンパク質及びその生成方法 |
| KR20180085717A (ko) | 2015-09-24 | 2018-07-27 | 에이비비트로, 엘엘씨 | 친화성-올리고뉴클레오타이드 콘쥬게이트 및 그것의 사용 |
| EP3452097A1 (en) | 2016-05-04 | 2019-03-13 | Navigo Proteins GmbH | Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker |
| SG11201901066UA (en) | 2016-08-11 | 2019-03-28 | Navigo Proteins Gmbh | Novel alkaline stable immunoglobulin-binding proteins |
| BR112019005748A2 (pt) | 2016-09-24 | 2019-06-18 | Abvitro Llc | afinidade-conjugados de oligonucleotídeo e usos destes |
| WO2019091918A1 (en) | 2017-11-07 | 2019-05-16 | Navigo Proteins Gmbh | Fusion proteins with specificity for ed-b and long serum half-life for diagnosis or treatment of cancer |
| MA54501A (fr) | 2018-12-18 | 2021-10-27 | Navigo Proteins Gmbh | Nouvelles protéines de liaison spécifiques de folr1 pour le diagnostic et le traitement du cancer |
| BR112022002365A2 (pt) | 2019-08-09 | 2022-04-26 | Nutcracker Therapeutics Inc | Métodos e aparelhos para fabricar e para remover material de uma composição terapêutica |
| EP4382534A1 (en) | 2022-12-06 | 2024-06-12 | Biomérieux | Synthetic peptide for use in an immunomolecular assay |
| EP4655590A1 (en) | 2023-01-27 | 2025-12-03 | Biomerieux | Modified immuno-molecular assay for faster biomarker detection |
| WO2025111396A1 (en) | 2023-11-20 | 2025-05-30 | Alamar Biosciences, Inc. | Molecular barcode set and use thereof in multiplex proximity detection assays |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06178688A (ja) * | 1992-12-11 | 1994-06-28 | Mitsui Toatsu Chem Inc | E型緑膿菌を抗原とするヒト抗体をコードする遺伝子 |
| AU8124694A (en) | 1993-10-29 | 1995-05-22 | Affymax Technologies N.V. | In vitro peptide and antibody display libraries |
| ES2253358T3 (es) | 2000-03-31 | 2006-06-01 | Cambridge Antibody Technology Limited | Mejoras en la visualizacion del ribosoma. |
-
1998
- 1998-05-28 JP JP50038699A patent/JP4060892B2/ja not_active Expired - Fee Related
- 1998-05-28 WO PCT/GB1998/001564 patent/WO1998054312A1/en not_active Ceased
- 1998-05-28 DE DE69818458T patent/DE69818458T3/de not_active Expired - Lifetime
- 1998-05-28 US US09/424,712 patent/US6620587B1/en not_active Expired - Lifetime
- 1998-05-28 EP EP98924468A patent/EP0985032B2/en not_active Expired - Lifetime
- 1998-05-28 DK DK98924468T patent/DK0985032T4/da active
- 1998-05-28 ES ES98924468T patent/ES2209145T5/es not_active Expired - Lifetime
- 1998-05-28 PT PT98924468T patent/PT985032E/pt unknown
- 1998-05-28 AT AT98924468T patent/ATE250668T1/de active
- 1998-05-28 CA CA2291721A patent/CA2291721C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2291721C (en) | 2011-08-09 |
| DE69818458D1 (de) | 2003-10-30 |
| PT985032E (pt) | 2004-02-27 |
| AU725957B2 (en) | 2000-10-26 |
| EP0985032A1 (en) | 2000-03-15 |
| DK0985032T4 (da) | 2009-08-31 |
| ES2209145T5 (es) | 2009-10-30 |
| US6620587B1 (en) | 2003-09-16 |
| CA2291721A1 (en) | 1998-12-03 |
| EP0985032B2 (en) | 2009-06-03 |
| AU7666698A (en) | 1998-12-30 |
| DK0985032T3 (da) | 2004-02-02 |
| WO1998054312A1 (en) | 1998-12-03 |
| DE69818458T2 (de) | 2004-07-08 |
| EP0985032B1 (en) | 2003-09-24 |
| ES2209145T3 (es) | 2004-06-16 |
| DE69818458T3 (de) | 2009-12-17 |
| ATE250668T1 (de) | 2003-10-15 |
| JP2002500514A (ja) | 2002-01-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4060892B2 (ja) | タンパク質のin vitroディスプレイ及び進化のための選択粒子としてのリボソーム複合体 | |
| US5922545A (en) | In vitro peptide and antibody display libraries | |
| Irving et al. | Ribosome display and affinity maturation: from antibodies to single V-domains and steps towards cancer therapeutics | |
| US10329555B2 (en) | High throughput generation and affinity maturation of humanized antibody | |
| JP3507073B2 (ja) | 特異的結合対の成員の製造方法 | |
| US20020068276A1 (en) | Methods for selecting functional polypeptides | |
| US12503693B2 (en) | Integrated system for library construction, affinity binder screening and expression thereof | |
| JP7772379B2 (ja) | 抗原特異的結合ポリペプチド遺伝子ディスプレイベクターの構築方法および用途 | |
| US20020076692A1 (en) | Ribosome display | |
| He et al. | Selection of a human anti-progesterone antibody fragment from a transgenic mouse library by ARM ribosome display | |
| WO1995011922A1 (en) | In vitro peptide and antibody display libraries | |
| KR20110076906A (ko) | 개선된 rna 디스플레이 방법 | |
| JP2003536048A (ja) | タンパク質の単離および分析 | |
| He et al. | Ribosome display of antibodies: expression, specificity and recovery in a eukaryotic system | |
| Azriel-Rosenfeld et al. | A human synthetic combinatorial library of arrayable single-chain antibodies based on shuffling in vivo formed CDRs into general framework regions | |
| WO1999011777A1 (en) | Methods for protein screening | |
| Contreras-Martínez et al. | Intracellular ribosome display via SecM translation arrest as a selection for antibodies with enhanced cytosolic stability | |
| EP3526330A1 (en) | Triple vector for expressing antibody molecules in full therapeutic format | |
| AU2003253193B2 (en) | Novel tricistronic vectors and uses therefor | |
| AU725957C (en) | Ribosome complexes as selection particles for in vitro display and evolution of proteins | |
| CN111201239A (zh) | 用于开发特异于表位翻译后修饰状态的抗体的方法和组合物 | |
| WO2004087914A1 (ja) | 抗体作製方法 | |
| Deen | Isolation of Human Endoplasmic Reticulum Antibodies Using Phage Display Technology | |
| WO2003097796A2 (en) | T7 bacteriophage display of fabs |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20050527 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20050527 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20070710 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20071010 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20071127 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20071221 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20101228 Year of fee payment: 3 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20101228 Year of fee payment: 3 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
| S533 | Written request for registration of change of name |
Free format text: JAPANESE INTERMEDIATE CODE: R313533 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20101228 Year of fee payment: 3 |
|
| R371 | Transfer withdrawn |
Free format text: JAPANESE INTERMEDIATE CODE: R371 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20101228 Year of fee payment: 3 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20101228 Year of fee payment: 3 |
|
| S533 | Written request for registration of change of name |
Free format text: JAPANESE INTERMEDIATE CODE: R313533 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20101228 Year of fee payment: 3 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20111228 Year of fee payment: 4 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20121228 Year of fee payment: 5 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20121228 Year of fee payment: 5 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20131228 Year of fee payment: 6 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |