DE69815703T2 - Verbindungen mit leicht spaltbaren bindungen zur inaktivierung von pathogenen - Google Patents
Verbindungen mit leicht spaltbaren bindungen zur inaktivierung von pathogenen Download PDFInfo
- Publication number
- DE69815703T2 DE69815703T2 DE69815703T DE69815703T DE69815703T2 DE 69815703 T2 DE69815703 T2 DE 69815703T2 DE 69815703 T DE69815703 T DE 69815703T DE 69815703 T DE69815703 T DE 69815703T DE 69815703 T2 DE69815703 T2 DE 69815703T2
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- Germany
- Prior art keywords
- alkyl
- heteroalkyl
- heteroaryl
- heteroalkylaryl
- alkylaryl
- Prior art date
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- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
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- C—CHEMISTRY; METALLURGY
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- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
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Landscapes
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Applications Claiming Priority (7)
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| US77983097A | 1997-01-07 | 1997-01-07 | |
| US779830 | 1997-01-07 | ||
| US4369697P | 1997-04-15 | 1997-04-15 | |
| US43696P | 1997-04-15 | ||
| PCT/US1998/000532 WO1998030545A1 (en) | 1997-01-06 | 1998-01-06 | Frangible compounds for pathogen inactivation |
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| DE69815703D1 DE69815703D1 (de) | 2003-07-24 |
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| EP (1) | EP1021414B1 (enExample) |
| JP (2) | JP4551502B2 (enExample) |
| CN (2) | CN1248245B (enExample) |
| AT (1) | ATE243198T1 (enExample) |
| AU (1) | AU744089C (enExample) |
| CA (1) | CA2276532C (enExample) |
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| ES (1) | ES2196530T3 (enExample) |
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| CA2276532C (en) * | 1997-01-06 | 2008-06-17 | Cerus Corporation | Frangible compounds for pathogen inactivation |
| CN1203900C (zh) | 1998-01-06 | 2005-06-01 | 塞鲁斯公司 | 用于淬灭生物材料中病原体灭活剂的方法 |
| JP2002517435A (ja) | 1998-06-11 | 2002-06-18 | シーラス コーポレイション | 動脈平滑筋細胞の増殖阻害のためのアルキル化化合物の使用 |
| US7498156B2 (en) | 1998-07-21 | 2009-03-03 | Caridianbct Biotechnologies, Llc | Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components |
| US7049110B2 (en) | 1998-07-21 | 2006-05-23 | Gambro, Inc. | Inactivation of West Nile virus and malaria using photosensitizers |
| US6403359B1 (en) | 1998-09-25 | 2002-06-11 | V. I. TECHNOLOGIES, Inc. | Solid phase quenching systems |
| US6150109A (en) | 1999-01-25 | 2000-11-21 | V. I. TECHNOLOGIES, Inc. | Lipophilic quenching of viral inactivating agents |
| US7220747B2 (en) | 1999-07-20 | 2007-05-22 | Gambro, Inc. | Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer |
| US7094378B1 (en) | 2000-06-15 | 2006-08-22 | Gambro, Inc. | Method and apparatus for inactivation of biological contaminants using photosensitizers |
| US20020042043A1 (en) * | 2000-05-31 | 2002-04-11 | Adonis Stassinopoulos | Preparation of a pathogen inactivated solution of red blood cells having reduced immunogenicity |
| US9044523B2 (en) | 2000-06-15 | 2015-06-02 | Terumo Bct, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
| DE10051628B4 (de) * | 2000-10-18 | 2007-06-06 | Fresenius Hemocare Beteiligungs Gmbh | Einzelsträngiges Oligonukleotid und dessen Verwendung |
| CA2434256A1 (en) * | 2000-12-21 | 2003-07-31 | David Cook | Methods for inactivation of pathogens in biological materials |
| PT1592441E (pt) | 2003-02-06 | 2012-05-21 | Aduro Biotech | Listeria atenuada relativamente à entrada em células não patogénicas, vacinas compreendendo a listeria e métodos para sua utilização |
| WO2004084936A2 (en) * | 2003-02-06 | 2004-10-07 | Cerus Corporation | Modified free-living microbes, vaccine compositions and methods of use thereof |
| US7695725B2 (en) | 2003-02-06 | 2010-04-13 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| US7842289B2 (en) | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
| CA2585621C (en) | 2004-10-29 | 2015-12-15 | Cerus Corporation | Improved quenching methods for red blood cell inactivation process |
| KR101896430B1 (ko) | 2008-04-09 | 2018-09-10 | 세루스 코포레이션 | 적혈구 병원체 불활성화를 위한 개선된 퀀칭 방법 |
| AU2014216178B2 (en) | 2013-02-15 | 2018-06-28 | KALA BIO, Inc. | Therapeutic compounds and uses thereof |
| US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
| EP2958895B1 (en) | 2013-02-20 | 2020-08-19 | Kala Pharmaceuticals, Inc. | Therapeutic compounds and uses thereof |
| US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| CA2928658A1 (en) | 2013-11-01 | 2015-05-07 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| CN104788373A (zh) * | 2015-05-06 | 2015-07-22 | 武汉大学 | 化合物s-303盐酸盐的合成方法 |
| EA201890149A1 (ru) | 2015-06-26 | 2018-07-31 | Сирус Корпорейшн | Композиции криопреципитатов и способы их получения |
| CN104991033A (zh) * | 2015-08-05 | 2015-10-21 | 上海海虹实业(集团)巢湖今辰药业有限公司 | 一种采用一测多评法测定川芎挥发油成分的方法 |
| US10799533B2 (en) | 2015-10-23 | 2020-10-13 | Cerus Corporation | Plasma compositions and methods of use thereof |
| CA3036340A1 (en) | 2016-09-08 | 2018-03-15 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| AU2017324713B2 (en) | 2016-09-08 | 2020-08-13 | KALA BIO, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| CA3036065A1 (en) | 2016-09-08 | 2018-03-15 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| AU2017382449B2 (en) | 2016-12-23 | 2024-10-24 | Cerus Corporation | Systems and methods for testing and screening using compound bound substrates |
| BR112019018273A2 (pt) | 2017-03-03 | 2020-07-14 | Cerus Corporation | kits e métodos para preparação de composições de plaquetas inativadas por patógenos |
| TWI821233B (zh) | 2017-12-29 | 2023-11-11 | 美商西勒斯股份有限公司 | 用於處理生物流體之方法、藉由該方法製備之病原體去活生物流體、及用於處理生物流體之系統 |
| CA3143213A1 (en) | 2019-06-22 | 2020-12-30 | Cerus Corporation | Biological fluid treatment systems |
| WO2020264421A1 (en) | 2019-06-28 | 2020-12-30 | Cerus Corporation | System and methods for implementing a biological fluid treatment device |
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| US5691132A (en) * | 1994-11-14 | 1997-11-25 | Cerus Corporation | Method for inactivating pathogens in red cell compositions using quinacrine mustard |
| DE4444045C2 (de) * | 1994-12-10 | 1997-04-17 | Behringwerke Ag | Verfahren zur Inaktivierung von Viren mit Hilfe von Acridin oder Acridinderivaten |
| AU722811B2 (en) * | 1995-06-07 | 2000-08-10 | Cerus Corporation | Treating red blood cell solutions with anti-viral agents |
| CA2276532C (en) * | 1997-01-06 | 2008-06-17 | Cerus Corporation | Frangible compounds for pathogen inactivation |
-
1998
- 1998-01-06 CA CA002276532A patent/CA2276532C/en not_active Expired - Fee Related
- 1998-01-06 CN CN988027348A patent/CN1248245B/zh not_active Expired - Lifetime
- 1998-01-06 WO PCT/US1998/000532 patent/WO1998030545A1/en not_active Ceased
- 1998-01-06 DE DE69815703T patent/DE69815703T2/de not_active Expired - Lifetime
- 1998-01-06 ES ES98901776T patent/ES2196530T3/es not_active Expired - Lifetime
- 1998-01-06 AU AU58217/98A patent/AU744089C/en not_active Expired
- 1998-01-06 JP JP53119998A patent/JP4551502B2/ja not_active Expired - Lifetime
- 1998-01-06 CN CN2009101633119A patent/CN101676268B/zh not_active Expired - Lifetime
- 1998-01-06 EP EP98901776A patent/EP1021414B1/en not_active Expired - Lifetime
- 1998-01-06 AT AT98901776T patent/ATE243198T1/de not_active IP Right Cessation
-
2009
- 2009-12-17 JP JP2009286996A patent/JP5244083B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU744089B2 (en) | 2002-02-14 |
| JP2001508449A (ja) | 2001-06-26 |
| ATE243198T1 (de) | 2003-07-15 |
| CA2276532A1 (en) | 1998-07-16 |
| EP1021414B1 (en) | 2003-06-18 |
| ES2196530T3 (es) | 2003-12-16 |
| HK1026702A1 (en) | 2000-12-22 |
| JP5244083B2 (ja) | 2013-07-24 |
| CN101676268A (zh) | 2010-03-24 |
| WO1998030545A1 (en) | 1998-07-16 |
| JP2010095527A (ja) | 2010-04-30 |
| CA2276532C (en) | 2008-06-17 |
| JP4551502B2 (ja) | 2010-09-29 |
| CN1248245B (zh) | 2012-07-04 |
| AU5821798A (en) | 1998-08-03 |
| AU744089C (en) | 2003-07-31 |
| DE69815703D1 (de) | 2003-07-24 |
| HK1188441A1 (en) | 2014-05-02 |
| CN101676268B (zh) | 2013-09-25 |
| CN1248245A (zh) | 2000-03-22 |
| EP1021414A1 (en) | 2000-07-26 |
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