ATE243198T1 - Verbindungen mit leicht spaltbaren bindungen zur inaktivierung von pathogenen - Google Patents
Verbindungen mit leicht spaltbaren bindungen zur inaktivierung von pathogenenInfo
- Publication number
- ATE243198T1 ATE243198T1 AT98901776T AT98901776T ATE243198T1 AT E243198 T1 ATE243198 T1 AT E243198T1 AT 98901776 T AT98901776 T AT 98901776T AT 98901776 T AT98901776 T AT 98901776T AT E243198 T1 ATE243198 T1 AT E243198T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- pathogens
- methods
- claveable
- inactivation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
- B01J20/28033—Membrane, sheet, cloth, pad, lamellar or mat
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/64—Acridine or hydrogenated acridine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- AIDS & HIV (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77983097A | 1997-01-06 | 1997-01-06 | |
US77988597A | 1997-01-06 | 1997-01-06 | |
US4369697P | 1997-04-15 | 1997-04-15 | |
PCT/US1998/000532 WO1998030545A1 (en) | 1997-01-06 | 1998-01-06 | Frangible compounds for pathogen inactivation |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE243198T1 true ATE243198T1 (de) | 2003-07-15 |
Family
ID=27366374
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98901776T ATE243198T1 (de) | 1997-01-06 | 1998-01-06 | Verbindungen mit leicht spaltbaren bindungen zur inaktivierung von pathogenen |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1021414B1 (de) |
JP (2) | JP4551502B2 (de) |
CN (2) | CN101676268B (de) |
AT (1) | ATE243198T1 (de) |
AU (1) | AU744089C (de) |
CA (1) | CA2276532C (de) |
DE (1) | DE69815703T2 (de) |
ES (1) | ES2196530T3 (de) |
HK (2) | HK1188441A1 (de) |
WO (1) | WO1998030545A1 (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998030545A1 (en) * | 1997-01-06 | 1998-07-16 | Cerus Corporation | Frangible compounds for pathogen inactivation |
AU745209B2 (en) * | 1998-01-06 | 2002-03-14 | Cerus Corporation | Methods for quenching pathogen inactivators in biological materials |
CA2332314A1 (en) * | 1998-06-11 | 1999-12-16 | Cerus Corporation | Use of alkylating compounds for inhibiting proliferation of arterial smooth muscle cells |
US6403359B1 (en) | 1998-09-25 | 2002-06-11 | V. I. TECHNOLOGIES, Inc. | Solid phase quenching systems |
US6150109A (en) | 1999-01-25 | 2000-11-21 | V. I. TECHNOLOGIES, Inc. | Lipophilic quenching of viral inactivating agents |
EP1284743A2 (de) * | 2000-05-31 | 2003-02-26 | Cerus Corporation | Bereitung von pathogeninaktivierter lösung von roter blutzellen mit reduzierter immunität |
US9044523B2 (en) | 2000-06-15 | 2015-06-02 | Terumo Bct, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
DE10051628B4 (de) * | 2000-10-18 | 2007-06-06 | Fresenius Hemocare Beteiligungs Gmbh | Einzelsträngiges Oligonukleotid und dessen Verwendung |
CA2434256A1 (en) * | 2000-12-21 | 2003-07-31 | David Cook | Methods for inactivation of pathogens in biological materials |
EP1592441B1 (de) | 2003-02-06 | 2012-04-11 | Aduro Biotech | Listerien deren eindringen in nicht-phagozytische zellen abgeschwächt ist, impfstoffe, die diese listerien enthalten und deren verwendungen |
CA2515298C (en) * | 2003-02-06 | 2014-04-08 | Cerus Corporation | Modified free-living microbes, vaccine compositions and methods of use thereof |
US7695725B2 (en) | 2003-02-06 | 2010-04-13 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
US7842289B2 (en) | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
BRPI0518198B8 (pt) | 2004-10-29 | 2021-06-22 | Cerus Corp | método ex vivo para tratar uma composição de células hemácias para inativar um patógeno, se presente, bem como composição e kit |
KR101742533B1 (ko) | 2008-04-09 | 2017-06-01 | 세루스 코포레이션 | 적혈구 병원체 불활성화를 위한 개선된 퀀칭 방법 |
WO2014127214A1 (en) | 2013-02-15 | 2014-08-21 | Kala Pharmaceuticals, Inc. | Therapeutic compounds and uses thereof |
ES2831625T3 (es) | 2013-02-20 | 2021-06-09 | Kala Pharmaceuticals Inc | Compuestos terapéuticos y sus usos |
US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
JP6426194B2 (ja) | 2013-11-01 | 2018-11-21 | カラ ファーマシューティカルズ インコーポレイテッド | 治療用化合物の結晶形態及びその使用 |
US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
CN104788373A (zh) * | 2015-05-06 | 2015-07-22 | 武汉大学 | 化合物s-303盐酸盐的合成方法 |
CN108135936A (zh) | 2015-06-26 | 2018-06-08 | 塞鲁斯公司 | 冷沉淀物组合物及其制备方法 |
CN104991033A (zh) * | 2015-08-05 | 2015-10-21 | 上海海虹实业(集团)巢湖今辰药业有限公司 | 一种采用一测多评法测定川芎挥发油成分的方法 |
US10799533B2 (en) | 2015-10-23 | 2020-10-13 | Cerus Corporation | Plasma compositions and methods of use thereof |
EP3509421A4 (de) | 2016-09-08 | 2020-05-20 | Kala Pharmaceuticals, Inc. | Kristalline formen therapeutischer verbindungen und verwendungen davon |
US10253036B2 (en) | 2016-09-08 | 2019-04-09 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
US10392399B2 (en) | 2016-09-08 | 2019-08-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
EA201991506A1 (ru) * | 2016-12-23 | 2020-01-23 | Сирус Корпорейшн | Системы и способы для тестирования и скрининга с использованием связанных с соединениями субстратов |
US11235090B2 (en) | 2017-03-03 | 2022-02-01 | Cerus Corporation | Kits and methods for preparing pathogen-inactivated platelet compositions |
AU2018395525B2 (en) | 2017-12-29 | 2023-09-14 | Cerus Corporation | Systems and methods for treating biological fluids |
WO2020264421A1 (en) | 2019-06-28 | 2020-12-30 | Cerus Corporation | System and methods for implementing a biological fluid treatment device |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994020090A1 (en) * | 1993-03-17 | 1994-09-15 | Steritech, Inc. | Decontaminating clinical samples |
US5691132A (en) * | 1994-11-14 | 1997-11-25 | Cerus Corporation | Method for inactivating pathogens in red cell compositions using quinacrine mustard |
DE4444045C2 (de) * | 1994-12-10 | 1997-04-17 | Behringwerke Ag | Verfahren zur Inaktivierung von Viren mit Hilfe von Acridin oder Acridinderivaten |
EP0773716A4 (de) * | 1995-06-07 | 1999-08-04 | Cerus Corp | Behandlung von lösungen roter blutkörperchen mit antivralen wirkstoffen |
WO1998030545A1 (en) * | 1997-01-06 | 1998-07-16 | Cerus Corporation | Frangible compounds for pathogen inactivation |
-
1998
- 1998-01-06 WO PCT/US1998/000532 patent/WO1998030545A1/en active IP Right Grant
- 1998-01-06 AT AT98901776T patent/ATE243198T1/de not_active IP Right Cessation
- 1998-01-06 CN CN2009101633119A patent/CN101676268B/zh not_active Expired - Lifetime
- 1998-01-06 CN CN988027348A patent/CN1248245B/zh not_active Expired - Lifetime
- 1998-01-06 DE DE69815703T patent/DE69815703T2/de not_active Expired - Lifetime
- 1998-01-06 CA CA002276532A patent/CA2276532C/en not_active Expired - Fee Related
- 1998-01-06 AU AU58217/98A patent/AU744089C/en not_active Expired
- 1998-01-06 ES ES98901776T patent/ES2196530T3/es not_active Expired - Lifetime
- 1998-01-06 EP EP98901776A patent/EP1021414B1/de not_active Expired - Lifetime
- 1998-01-06 JP JP53119998A patent/JP4551502B2/ja not_active Expired - Lifetime
-
2000
- 2000-09-20 HK HK10109160.3A patent/HK1188441A1/xx not_active IP Right Cessation
- 2000-09-20 HK HK00105911.5A patent/HK1026702A1/xx not_active IP Right Cessation
-
2009
- 2009-12-17 JP JP2009286996A patent/JP5244083B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2001508449A (ja) | 2001-06-26 |
AU744089C (en) | 2003-07-31 |
JP4551502B2 (ja) | 2010-09-29 |
AU744089B2 (en) | 2002-02-14 |
CN101676268B (zh) | 2013-09-25 |
EP1021414A1 (de) | 2000-07-26 |
ES2196530T3 (es) | 2003-12-16 |
HK1026702A1 (en) | 2000-12-22 |
CN1248245A (zh) | 2000-03-22 |
CN101676268A (zh) | 2010-03-24 |
CA2276532A1 (en) | 1998-07-16 |
DE69815703D1 (de) | 2003-07-24 |
CA2276532C (en) | 2008-06-17 |
DE69815703T2 (de) | 2004-06-03 |
CN1248245B (zh) | 2012-07-04 |
AU5821798A (en) | 1998-08-03 |
JP2010095527A (ja) | 2010-04-30 |
HK1188441A1 (en) | 2014-05-02 |
WO1998030545A1 (en) | 1998-07-16 |
JP5244083B2 (ja) | 2013-07-24 |
EP1021414B1 (de) | 2003-06-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |