DE69718495T2 - System zur medikamentenabgabe durch transport - Google Patents

System zur medikamentenabgabe durch transport

Info

Publication number
DE69718495T2
DE69718495T2 DE69718495T DE69718495T DE69718495T2 DE 69718495 T2 DE69718495 T2 DE 69718495T2 DE 69718495 T DE69718495 T DE 69718495T DE 69718495 T DE69718495 T DE 69718495T DE 69718495 T2 DE69718495 T2 DE 69718495T2
Authority
DE
Germany
Prior art keywords
porous medium
substance
plate
dermis
fluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69718495T
Other languages
German (de)
English (en)
Other versions
DE69718495D1 (de
Inventor
L. Kamen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deka Products LP
Original Assignee
Deka Products LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deka Products LP filed Critical Deka Products LP
Application granted granted Critical
Publication of DE69718495D1 publication Critical patent/DE69718495D1/de
Publication of DE69718495T2 publication Critical patent/DE69718495T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Refuse Collection And Transfer (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Surgical Instruments (AREA)
DE69718495T 1996-09-17 1997-09-15 System zur medikamentenabgabe durch transport Expired - Lifetime DE69718495T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2626696P 1996-09-17 1996-09-17
US3903697P 1997-02-24 1997-02-24
PCT/US1997/016454 WO1998011937A1 (en) 1996-09-17 1997-09-15 System for delivery of drugs by transport

Publications (2)

Publication Number Publication Date
DE69718495D1 DE69718495D1 (de) 2003-02-20
DE69718495T2 true DE69718495T2 (de) 2003-11-20

Family

ID=26700996

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69718495T Expired - Lifetime DE69718495T2 (de) 1996-09-17 1997-09-15 System zur medikamentenabgabe durch transport

Country Status (7)

Country Link
US (1) US5983136A (enExample)
EP (1) EP0934093B1 (enExample)
JP (2) JP4054381B2 (enExample)
AT (1) ATE231015T1 (enExample)
CA (1) CA2265906C (enExample)
DE (1) DE69718495T2 (enExample)
WO (1) WO1998011937A1 (enExample)

Families Citing this family (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996037256A1 (en) * 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical patch for enhancing the delivery of compounds through the skin
US5814094A (en) 1996-03-28 1998-09-29 Becker; Robert O. Iontopheretic system for stimulation of tissue healing and regeneration
US6861570B1 (en) * 1997-09-22 2005-03-01 A. Bart Flick Multilayer conductive appliance having wound healing and analgesic properties
US7214847B1 (en) 1997-09-22 2007-05-08 Argentum Medical, L.L.C. Multilayer conductive appliance having wound healing and analgesic properties
US8455710B2 (en) * 1997-09-22 2013-06-04 Argentum Medical, Llc Conductive wound dressings and methods of use
US8801681B2 (en) * 1995-09-05 2014-08-12 Argentum Medical, Llc Medical device
CA2253549C (en) * 1996-06-18 2005-10-25 Alza Corporation Device for enhancing transdermal agent delivery or sampling
US7922709B2 (en) 1998-07-13 2011-04-12 Genetronics, Inc. Enhanced delivery of naked DNA to skin by non-invasive in vivo electroporation
US6678556B1 (en) * 1998-07-13 2004-01-13 Genetronics, Inc. Electrical field therapy with reduced histopathological change in muscle
CA2337652C (en) * 1998-07-13 2013-03-26 Genetronics, Inc. Skin and muscle-targeted gene therapy by pulsed electrical field
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
AU6076200A (en) 1999-07-08 2001-01-30 Johnson & Johnson Consumer Companies, Inc. Exothermic bandage
US20030078499A1 (en) * 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US7133717B2 (en) 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US6431174B1 (en) * 2000-08-10 2002-08-13 Pi Medical, Inc. Method and apparatus to treat conditions of the naso-pharyngeal area
US6502574B2 (en) 1999-09-17 2003-01-07 Pi Medical, Inc. Lateral stiffening snoring treatment
US6231561B1 (en) * 1999-09-20 2001-05-15 Appriva Medical, Inc. Method and apparatus for closing a body lumen
US8465468B1 (en) 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
EP1235611B1 (en) * 1999-11-15 2005-09-07 Velcro Industries B.V. Skin attachment member
ES2253278T3 (es) 1999-12-10 2006-06-01 Alza Corporation Dispositivo y procedimiento para mejorar la perforacion cutanea con microprotuberancias.
US6497676B1 (en) 2000-02-10 2002-12-24 Baxter International Method and apparatus for monitoring and controlling peritoneal dialysis therapy
US7404815B2 (en) * 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US6659982B2 (en) * 2000-05-08 2003-12-09 Sterling Medivations, Inc. Micro infusion drug delivery device
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US6440096B1 (en) * 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
KR100764699B1 (ko) 2000-09-08 2007-10-08 알자 코포레이션 경로 폐쇄 저해에 의한 경피 약물 플럭스 감소 저해방법
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
AU9681701A (en) * 2000-10-13 2002-04-22 Alza Corp Microprotrusion member retainer for impact applicator
AU2001296828B2 (en) 2000-10-13 2005-11-24 Alza Corporation Apparatus and method for piercing skin with microprotrusions
BR0114634A (pt) 2000-10-13 2004-01-27 Alza Corp Aplicador por impacto de disposição de microlâmina
US7108681B2 (en) 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
WO2002094368A1 (en) 2000-10-26 2002-11-28 Alza Corporation Transdermal drug delivery devices having coated microprotrusions
KR100774900B1 (ko) 2001-01-31 2007-11-09 벨크로 인더스트리스 비.브이. 직접적인 후크 맞물림 구조
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US6855372B2 (en) 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
US7963935B2 (en) 2001-04-20 2011-06-21 Alza Corporation Microprojection array having a beneficial agent containing coating
EP3251722B1 (en) 2001-04-20 2020-06-17 ALZA Corporation Microprojection array having a beneficial agent containing coating and method of forming the coating thereon
US6855117B2 (en) 2001-08-01 2005-02-15 Johnson & Johnson Consumer Companies, Inc. Method of treating the skin of a subject
US6840910B2 (en) 2001-08-01 2005-01-11 Johnson & Johnson Consumer Companies, Inc. Method of distributing skin care products
US6790179B2 (en) 2001-08-01 2004-09-14 Johnson & Johnson Consumer Companies, Inc. Method of examining and diagnosing skin health
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US20040120964A1 (en) * 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
AU2002365144A1 (en) * 2001-10-29 2003-06-30 Becton, Dickinson And Company Method and device for the delivery of a substance
US20030125662A1 (en) 2002-01-03 2003-07-03 Tuan Bui Method and apparatus for providing medical treatment therapy based on calculated demand
US7146981B2 (en) 2002-02-04 2006-12-12 Restore Medical, Inc. Pharyngeal wall treatment
US7017582B2 (en) * 2002-02-04 2006-03-28 Restore Medical Inc. Stiffening pharyngeal wall treatment
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
US8116860B2 (en) 2002-03-11 2012-02-14 Altea Therapeutics Corporation Transdermal porator and patch system and method for using same
WO2003077971A2 (en) 2002-03-11 2003-09-25 Altea Therapeutics Corporation Transdermal drug delivery patch system, method of making same and method of using same
US6945952B2 (en) * 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
US7238164B2 (en) 2002-07-19 2007-07-03 Baxter International Inc. Systems, methods and apparatuses for pumping cassette-based therapies
BR0312671A (pt) 2002-07-19 2005-04-26 3M Innovative Properties Co Dispositivo de microagulhas, método para utilizar um dispositivo de microagulhas, e, método para aplicar um dispositivo de microagulhas
US20040194266A1 (en) * 2002-08-19 2004-10-07 Carter Linda A. Burn, sunburn, and cellulite treatment system
JP4460451B2 (ja) * 2002-08-29 2010-05-12 ベクトン・ディキンソン・アンド・カンパニー 回転マイクロ剥離面による物質送達
US8062573B2 (en) * 2002-09-16 2011-11-22 Theraject, Inc. Solid micro-perforators and methods of use
US20040236269A1 (en) 2002-09-25 2004-11-25 Marchitto Kevin S. Microsurgical tissue treatment system
WO2004028351A2 (en) * 2002-09-27 2004-04-08 Surgifile, Inc. Shielded reciprocating surgical file
US7666186B2 (en) * 2002-09-27 2010-02-23 Surgitech, Llc Surgical system with a blade
US6896666B2 (en) * 2002-11-08 2005-05-24 Kochamba Family Trust Cutaneous injection delivery under suction
US20060264926A1 (en) * 2002-11-08 2006-11-23 Kochamba Gary S Cutaneous stabilization by vacuum for delivery of micro-needle array
US7381222B2 (en) * 2002-12-30 2008-06-03 Quiescence Medical, Inc. Stent for maintaining patency of a body region
US7992566B2 (en) 2002-12-30 2011-08-09 Quiescence Medical, Inc. Apparatus and methods for treating sleep apnea
US7647931B2 (en) 2002-12-30 2010-01-19 Quiescence Medical, Inc. Stent for maintaining patency of a body region
US7578954B2 (en) 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
AU2004255218A1 (en) 2003-06-30 2005-01-20 Alza Corporation Formulations for coated microprojections containing non-volatile counterions
PE20050288A1 (es) * 2003-07-02 2005-04-29 Alza Corp Metodo y parche de inmunizacion por disposicion de microproyeccion
CA2536249A1 (en) 2003-08-25 2005-03-10 3M Innovative Properties Company Delivery of immune response modifier compounds
CN1842355A (zh) * 2003-08-26 2006-10-04 阿尔扎公司 用于皮内细胞植入的装置和方法
US8016811B2 (en) 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
EP1675539A4 (en) 2003-10-24 2007-09-12 Alza Corp METHOD AND SYSTEM FOR PRETREATMENT FOR IMPROVING TRANSDERMAL DRUG DELIVERY
KR20060120156A (ko) 2003-10-28 2006-11-24 알자 코포레이션 담배의 이용빈도를 감소시키기 위한 방법 및 장치
EP1680154B1 (en) 2003-10-31 2012-01-04 ALZA Corporation Self-actuating applicator for microprojection array
AU2004311977A1 (en) * 2003-12-29 2005-07-21 3M Innovative Properties Company Medical devices and kits including same
JP2007523771A (ja) * 2004-02-23 2007-08-23 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの成形方法
CA2560840C (en) 2004-03-24 2014-05-06 Corium International, Inc. Transdermal delivery device
EP1744683B1 (en) 2004-05-13 2016-03-16 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
US20080039805A1 (en) * 2004-06-10 2008-02-14 Frederickson Franklyn L Patch Application Device and Kit
US7316665B2 (en) * 2004-08-25 2008-01-08 Becton, Dickinson And Company Method and device for the delivery of a substance including a covering
AU2005282401A1 (en) * 2004-09-08 2006-03-16 Alza Corporation Microprojection array with improved skin adhesion and compliance
WO2006055795A1 (en) 2004-11-18 2006-05-26 3M Innovative Properties Company Low-profile microneedle array applicator
JP5015787B2 (ja) 2004-11-18 2012-08-29 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの接触コーティング法
JP4927752B2 (ja) 2004-11-18 2012-05-09 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイアプリケーターおよび保持装置
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
CA2588080C (en) * 2004-11-18 2013-01-08 3M Innovative Properties Company Masking method for coating a microneedle array
CN101124072B (zh) * 2004-11-26 2010-05-26 新加坡科技研究局 形成微结构的方法和装置
CN102358015A (zh) 2004-12-07 2012-02-22 3M创新有限公司 模制微型针的方法
WO2006108185A1 (en) 2005-04-07 2006-10-12 3M Innovative Properties Company System and method for tool feedback sensing
US20070270738A1 (en) * 2005-04-25 2007-11-22 Wu Jeffrey M Method of treating ACNE with stratum corneum piercing patch
US20080009802A1 (en) * 2005-04-25 2008-01-10 Danilo Lambino Method of treating acne with stratum corneum piercing device
US20060253079A1 (en) * 2005-04-25 2006-11-09 Mcdonough Justin Stratum corneum piercing device
US20080195035A1 (en) 2005-06-24 2008-08-14 Frederickson Franklyn L Collapsible Patch and Method of Application
CA2613114C (en) 2005-06-27 2015-02-24 3M Innovative Properties Company Microneedle cartridge assembly and method of applying
EP1901799B1 (en) 2005-06-27 2012-06-13 3M Innovative Properties Company Microneedle array applicator device
CN101687094B (zh) * 2005-09-06 2012-09-26 谢拉杰克特股份有限公司 含有药物颗粒和/或药物吸附颗粒的固体溶液穿孔器
US8900180B2 (en) * 2005-11-18 2014-12-02 3M Innovative Properties Company Coatable compositions, coatings derived therefrom and microarrays having such coatings
US20080262416A1 (en) * 2005-11-18 2008-10-23 Duan Daniel C Microneedle Arrays and Methods of Preparing Same
US20070142885A1 (en) * 2005-11-29 2007-06-21 Reliant Technologies, Inc. Method and Apparatus for Micro-Needle Array Electrode Treatment of Tissue
WO2007075614A1 (en) * 2005-12-21 2007-07-05 3M Innovative Properties Company Microneedle devices
US9119945B2 (en) 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
JP5406025B2 (ja) 2006-07-06 2014-02-05 クワイエセンス メディカル インコーポレイテッド 睡眠時無呼吸症処置用の装置及びシステム
AU2008209537B2 (en) 2007-01-22 2013-01-31 Corium Pharma Solutions, Inc. Applicators for microneedle arrays
US8870812B2 (en) 2007-02-15 2014-10-28 Baxter International Inc. Dialysis system having video display with ambient light adjustment
US7731689B2 (en) 2007-02-15 2010-06-08 Baxter International Inc. Dialysis system having inductive heating
US7998115B2 (en) 2007-02-15 2011-08-16 Baxter International Inc. Dialysis system having optical flowrate detection
US8558964B2 (en) 2007-02-15 2013-10-15 Baxter International Inc. Dialysis system having display with electromagnetic compliance (“EMC”) seal
US8361023B2 (en) 2007-02-15 2013-01-29 Baxter International Inc. Dialysis system with efficient battery back-up
AU2008241470B2 (en) 2007-04-16 2013-11-07 Corium Pharma Solutions, Inc. Solvent-cast microneedle arrays containing active
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
US20090216204A1 (en) 2008-02-27 2009-08-27 Sai Bhavaraju Auto-replenishing, wound-dressing apparatus and method
KR101383285B1 (ko) * 2008-05-21 2014-04-08 테라젝트, 인코포레이티드 고용체 퍼포레이터 패치의 제조 방법 및 그 사용
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル， インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
JP2014500275A (ja) 2010-12-06 2014-01-09 フォリカ，インコーポレイテッド 禿頭症を治療するため、および毛髪の成長を促進するための方法
US9265649B2 (en) 2010-12-13 2016-02-23 Quiescence Medical, Inc. Apparatus and methods for treating sleep apnea
MX375307B (es) 2012-12-21 2025-03-06 Corium Inc Microarreglo para la entrega de agente terapeutico y metodos de uso.
WO2014126101A1 (ja) 2013-02-13 2014-08-21 久光製薬株式会社 マイクロニードル・アレイ
WO2014164314A1 (en) 2013-03-12 2014-10-09 Corium International, Inc. Microprojection applicators
JP2016512754A (ja) 2013-03-15 2016-05-09 コリウム インターナショナル， インコーポレイテッド 治療剤の送達のためのマイクロアレイ、使用方法および製造方法
ES2939317T3 (es) 2013-03-15 2023-04-20 Corium Pharma Solutions Inc Aplicadores de microproyección de impacto múltiple
AU2014233695A1 (en) 2013-03-15 2015-10-01 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
EP2968116A1 (en) 2013-03-15 2016-01-20 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US20150038897A1 (en) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Low-Profile Microneedle Patch Applicator
EP2905047A1 (de) * 2014-02-10 2015-08-12 LTS LOHMANN Therapie-Systeme AG Mikronadelsystem und Verfahren seiner Herstellung
EP3188714A1 (en) 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
EP3380061B1 (en) 2015-11-24 2025-04-09 Insulet Corporation Wearable automated medication delivery system
US11179516B2 (en) 2017-06-22 2021-11-23 Baxter International Inc. Systems and methods for incorporating patient pressure into medical fluid delivery
KR102291392B1 (ko) * 2018-03-30 2021-08-20 랩앤피플주식회사 멀티형 마이크로 니들
EP4262921A1 (en) 2020-12-18 2023-10-25 Insulet Corporation Adhesive pad with a metallic coil for securing an on-body medical device
US12357804B2 (en) 2021-03-01 2025-07-15 Deka Products Limited Partnership Medical agent dispensing systems, methods, and apparatuses
US12161832B2 (en) 2021-03-01 2024-12-10 Deka Products Limited Partnership Medical agent dispensing systems, methods, and apparatuses
EP4301433A1 (en) 2021-03-01 2024-01-10 DEKA Products Limited Partnership Medical agent dispensing apparatuses, systems, and methods
IL315300A (en) 2022-03-03 2024-10-01 Deka Products Lp Systems and devices for administering medicine to a patient
WO2024019793A1 (en) 2022-07-21 2024-01-25 Deka Products Limited Partnership Delivery device systems, methods, and apparatuses

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3617613A (en) * 1968-10-17 1971-11-02 Spaulding Fibre Co Punchable printed circuit board base
US3675766A (en) * 1970-02-04 1972-07-11 Sol Roy Rosenthal Multiple puncture injector device
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
GB2047543B (en) * 1978-12-06 1983-04-20 Svedman Paul Device for treating tissues for example skin
US4421508A (en) * 1981-02-24 1983-12-20 Cohen Edgar C Vacuum-compression injector
US4403609A (en) * 1981-02-24 1983-09-13 Cohen Edgar C Vacuum-compression injector
US4340048A (en) * 1981-03-28 1982-07-20 Alza Corporation Self-driven hypodermic injector
US4447225A (en) * 1982-03-22 1984-05-08 Taff Barry E Multidose jet injector
EP0209644A1 (en) * 1985-05-02 1987-01-28 Ivac Corporation Electrochemically driven drug dispenser
US4711247A (en) * 1986-04-18 1987-12-08 Henry Fishman Allergy testing method and apparatus
US5080648A (en) * 1987-06-08 1992-01-14 Antonio Nicholas F D Hypodermic fluid dispenser
DE3735137A1 (de) * 1987-10-16 1989-05-03 Siemens Ag Anordnung zum abgeben von medikamenten bei einem implantierbaren medizinischen geraet
EP0347190A1 (en) * 1988-06-14 1989-12-20 Vci Corporation Needleless vacuum-compression injector
GB2221394B (en) * 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
JPH02144077A (ja) * 1988-11-25 1990-06-01 Olympus Optical Co Ltd 薬物投与装置
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
SE9101022D0 (sv) * 1991-01-09 1991-04-08 Paal Svedman Medicinsk suganordning
US5312456A (en) * 1991-01-31 1994-05-17 Carnegie Mellon University Micromechanical barb and method for making the same
US5153986A (en) * 1991-07-17 1992-10-13 International Business Machines Method for fabricating metal core layers for a multi-layer circuit board
US5484399A (en) * 1992-02-27 1996-01-16 Sloan-Kettering Institute For Cancer Research Process and device to reduce interstitial fluid pressure in tissue
US5309909A (en) * 1992-05-22 1994-05-10 Physio-Control Corporation Combined skin preparation and monitoring electrode
US5702359A (en) * 1995-06-06 1997-12-30 Genetronics, Inc. Needle electrodes for mediated delivery of drugs and genes
IE68890B1 (en) * 1993-04-08 1996-07-24 Elan Med Tech Intradermal delivery device
AU4256496A (en) * 1994-12-09 1996-06-26 Novartis Ag Transdermal system
HK1009321A1 (en) * 1995-08-29 1999-05-28 Nitto Denko Corporation Microporation of human skin for drug delivery and monitoring applications
ES2200187T3 (es) * 1996-07-03 2004-03-01 Altea Therapeutics Corporation Microporacion mecanica multiple de la piel o de la mucosa.

Also Published As

Publication number Publication date
EP0934093A1 (en) 1999-08-11
US5983136A (en) 1999-11-09
EP0934093B1 (en) 2003-01-15
WO1998011937A1 (en) 1998-03-26
CA2265906A1 (en) 1998-03-26
DE69718495D1 (de) 2003-02-20
JP4054381B2 (ja) 2008-02-27
JP2007325955A (ja) 2007-12-20
ATE231015T1 (de) 2003-02-15
JP2002510982A (ja) 2002-04-09
CA2265906C (en) 2003-11-11

Similar Documents

Publication Publication Date Title
DE69718495T2 (de) System zur medikamentenabgabe durch transport
DE69722414T2 (de) Mehrfache mechanische mikroperforierung von haut oder schleimhäuten
DE60124917T2 (de) Mikrovorrichtung und verfahren zur herstellung
DE60117543T2 (de) Vorrichtung zum erhöhen der permeabilität der haut zum zwecke der entnahme oder zuführung einer substanz
DE60314157T2 (de) Verfahren und vorrichtung zur epidermischen verabreichung einer substanz
DE60116764T2 (de) Vorrichtung zum verbessern der penetrierbarkeit eines punktierelementes in den intradermalen raum
DE60113557T2 (de) Mikrostrukturen zur kutanen verabreichung eines mittels auf die haut
DE60122723T2 (de) Vorrichtung zur transdermalen Abnahme und Verabreichung von einer Substanz beim Patient
DE69831268T2 (de) Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
EP0796128B1 (de) Transdermales system
DE60309454T2 (de) Mit einem ventil versehenes gerät zur intradermalen verabreichung
DE60018796T2 (de) Vorrichtung zur erhöhung des transdermalen flusses von probenwirkstoffen
DE60106261T2 (de) Abgabevorrichtung mit mikronadeln zur transdermalen verabreichung von einer substanz
DE60224842T2 (de) Mikronadel-vorrichtungen und verfahren zur herstellung
DE69626413T2 (de) Medizinisches ventil mit ringartiger dichtung
DE69922014T2 (de) Vorrichtung zur abgabe eines stoffes ausgerüstet mit einer oder mehreren mit hoher geschwindigkeit angetriebenen nadeln
DE60305901T2 (de) Gerät zur intradermalen verabreichung von medikamenten
DE60213976T2 (de) Vorrichtung zur manipulation von nadeln oder polierarray
DE69001812T2 (de) System zur parenteralen verabreichung eines wirkstoffs.
DE69718912T2 (de) Nadel zur subkutanen verabreichung von flüssigkeiten
DE69113663T2 (de) Verbesserungen an implantierbaren vaskularen Anschlussvorrichtungen.
DE60032082T2 (de) Vorrichtung zur transdermalen Verabreichung von einer Substanz
DE3886046T2 (de) Sich selbst stumpf machende nadeleinheit sowie diese aufweisende vorrichtung.
DE102008052749B4 (de) Nadel, Nadelanordnung, Spritzgussform und Verfahren zum Herstellen
DE10003507B4 (de) Vorrichtung und Verfahren zur Entnahme von Flüssigkeiten aus körpereigenem Gewebe und Bestimmung von Stoffkonzentrationen in dieser Flüssigkeit

Legal Events

Date Code Title Description
8364 No opposition during term of opposition