DE69634903D1 - Hyaluronidase zusammensetzungen zur behandlung intravitrealen hemorrhagischen blutes - Google Patents

Hyaluronidase zusammensetzungen zur behandlung intravitrealen hemorrhagischen blutes

Info

Publication number
DE69634903D1
DE69634903D1 DE69634903T DE69634903T DE69634903D1 DE 69634903 D1 DE69634903 D1 DE 69634903D1 DE 69634903 T DE69634903 T DE 69634903T DE 69634903 T DE69634903 T DE 69634903T DE 69634903 D1 DE69634903 D1 DE 69634903D1
Authority
DE
Germany
Prior art keywords
intravitreal
treatment
hyaluronidase
blood
hemorrhagic blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69634903T
Other languages
English (en)
Other versions
DE69634903T2 (de
Inventor
Hampar L Karageozian
Vicken H Karageozian
Maria C Kenney
Jose L G Flores
Gabriel A C Aragon
Anthony B Nesburn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISTA Pharmaceuticals Inc
Original Assignee
ISTA Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ISTA Pharmaceuticals Inc filed Critical ISTA Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69634903D1 publication Critical patent/DE69634903D1/de
Publication of DE69634903T2 publication Critical patent/DE69634903T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DE69634903T 1995-11-22 1996-11-20 Hyaluronidase zusammensetzungen zur behandlung intravitrealen hemorrhagischen blutes Expired - Lifetime DE69634903T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/561,636 US5866120A (en) 1995-11-22 1995-11-22 Method for accelerating clearance of hemorrhagic blood from the vitreous humor with hyaluronidase
US561636 1995-11-22
PCT/US1996/018843 WO1997018835A1 (en) 1995-11-22 1996-11-20 Enzymatic method and compositions for treating intravitreal hemorrhagic blood

Publications (2)

Publication Number Publication Date
DE69634903D1 true DE69634903D1 (de) 2005-08-04
DE69634903T2 DE69634903T2 (de) 2006-05-18

Family

ID=24242789

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69634903T Expired - Lifetime DE69634903T2 (de) 1995-11-22 1996-11-20 Hyaluronidase zusammensetzungen zur behandlung intravitrealen hemorrhagischen blutes

Country Status (15)

Country Link
US (5) US5866120A (de)
EP (1) EP0862456B1 (de)
JP (1) JP2000502325A (de)
KR (1) KR100463009B1 (de)
CN (1) CN1207684A (de)
AT (1) ATE298584T1 (de)
AU (1) AU1407097A (de)
BR (1) BR9611617A (de)
CA (1) CA2238360C (de)
DE (1) DE69634903T2 (de)
DK (1) DK0862456T3 (de)
ES (1) ES2245458T3 (de)
MX (1) MX9804051A (de)
PT (1) PT862456E (de)
WO (1) WO1997018835A1 (de)

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US6610292B2 (en) 1995-11-22 2003-08-26 Ista Pharmaceuticals, Inc. Use of hyaluronidase in the manufacture of an ophthalmic preparation for liquefying vitreous humor in the treatment of eye disorders
PT983084E (pt) * 1997-05-22 2007-04-30 Ista Pharmaceuticals Inc Utilização de hialuronidase na fabricação de uma preparação oftálmica para liquefacção do humor vítreo no tratamento de pertubações oculares
ATE308293T1 (de) * 1998-03-09 2005-11-15 Ista Pharmaceuticals Inc Verwendung von glyceraldehyde als hornhaut härtungsmitteln
US7008960B1 (en) 1999-03-02 2006-03-07 Vitreo-Retinal Technologies, Inc. Agents for intravitreal administration to treat or prevent disorders of the eye
US6335006B1 (en) 1999-03-22 2002-01-01 Boston Innovative Optics, Inc. Methods of using agents that act on the epithelial sheet of a human eye
DK1173198T3 (da) * 1999-04-29 2004-04-13 Ista Pharmaceuticals Inc Anvendelse af en bestemt hyaluronidase til eliminering af ar på, uigennemsigtighed og uklarhed på hornhinden
AU4511201A (en) 1999-12-03 2001-06-12 Ista Pharmaceuticals, Inc Compositions and methods for the induction and treatment of retinal detachments
US20030199574A1 (en) * 2000-03-02 2003-10-23 Vitreo-Retinal Technologies, Inc. Treatment of ophthalmic disorders using urea and urea derivatives
US7977385B2 (en) * 2000-03-02 2011-07-12 Numoda Biotechnologies, Inc. Agents for corneal or intrastromal administration to treat or prevent disorders of the eye
US7141607B1 (en) 2000-03-10 2006-11-28 Insite Vision Incorporated Methods and compositions for treating and inhibiting retinal neovascularization
US6902548B1 (en) * 2001-03-19 2005-06-07 Ed Schuler Use of Streptomyces hyalurolyticus enzyme in ophthalmic treatments
US6745776B2 (en) 2001-04-10 2004-06-08 David B. Soll Methods for reducing postoperative intraocular pressure
US7115408B1 (en) 2001-05-02 2006-10-03 Ista Pharmaceuticals, Inc. Method of stabilizing hyaluronidase with annexin II
ES2378227T3 (es) * 2001-08-13 2012-04-10 University Of Florida Research Foundation, Inc. Materiales y métodos para favorecer la reparación del tejido nervioso
WO2003102160A2 (en) * 2002-06-03 2003-12-11 Massachusetts Institute Of Technology Rationally designed polysaccharide lyases derived from chondroitinase b
US20050137124A1 (en) * 2002-08-09 2005-06-23 Vitreo-Retinal Technologies, Inc. A California Corporation Agents for intravitreal administration to treat or prevent disorders of the eye
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US6969514B2 (en) 2003-02-05 2005-11-29 Soll David B Method for treating elevated intraocular pressure, including glaucoma
US8012115B2 (en) 2003-02-18 2011-09-06 S.K. Pharmaceuticals, Inc. Optic nerve implants
JP2006523461A (ja) * 2003-04-15 2006-10-19 イスタ・ファーマスーティカルズ・インコーポレイテッド 羊ヒアルロニダーゼを単離し精製する方法
MXPA03011987A (es) 2003-12-19 2005-06-23 Osio Sancho Alberto Metodo para el tratamiento de la presbicia induciendo cambios en el poder y fisiologia corneal.
WO2005118799A1 (en) * 2004-04-15 2005-12-15 Ista Pharmaceuticals, Inc. Ovine hyaluronidase
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CN102266348A (zh) * 2011-08-04 2011-12-07 山西诺成制药有限公司 一种眼内冲洗液及其制备方法
RU2647783C2 (ru) 2012-08-10 2018-03-19 Осио Корпорейшн Д/Б/А Иолиа Хелт Использование контактных линз при лечении офтальмологического нарушения
US8790711B2 (en) 2012-09-17 2014-07-29 Biopep Solutions, Inc. Treating diabetes with a whole, leech saliva extract
KR101454646B1 (ko) 2012-11-05 2014-10-27 (주)한국비엠아이 히알루로니다아제의 안정화 제제 및 이를 포함하는 액상제제
US20140212404A1 (en) * 2012-11-14 2014-07-31 Khizer Khaderi Compositions and Methods for Treating Injuries to the Visual System of a Human
TW202202168A (zh) * 2020-07-07 2022-01-16 洪啟庭 用於改善玻璃體混濁的組成物及其應用
CN113769073A (zh) * 2021-10-15 2021-12-10 杭州鑫伟低碳技术研发有限公司 一种利用生物酶治疗眼底出血的方法

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Also Published As

Publication number Publication date
ES2245458T3 (es) 2006-01-01
US20060034822A1 (en) 2006-02-16
US6039943A (en) 2000-03-21
DK0862456T3 (da) 2005-10-17
CN1207684A (zh) 1999-02-10
US20030129182A1 (en) 2003-07-10
CA2238360C (en) 2009-09-01
US5866120A (en) 1999-02-02
DE69634903T2 (de) 2006-05-18
EP0862456A1 (de) 1998-09-09
AU1407097A (en) 1997-06-11
US6939542B2 (en) 2005-09-06
JP2000502325A (ja) 2000-02-29
WO1997018835A1 (en) 1997-05-29
CA2238360A1 (en) 1997-05-29
BR9611617A (pt) 1999-04-06
KR100463009B1 (ko) 2005-02-28
US20020071837A1 (en) 2002-06-13
US6551590B2 (en) 2003-04-22
ATE298584T1 (de) 2005-07-15
EP0862456B1 (de) 2005-06-29
EP0862456A4 (de) 2003-02-12
PT862456E (pt) 2005-11-30
KR19990071565A (ko) 1999-09-27
MX9804051A (es) 1998-12-31

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