MX9804051A - Metodo enzimatico y composiciones para tratar la sangre hemorragica intravitrea. - Google Patents

Metodo enzimatico y composiciones para tratar la sangre hemorragica intravitrea.

Info

Publication number
MX9804051A
MX9804051A MX9804051A MX9804051A MX9804051A MX 9804051 A MX9804051 A MX 9804051A MX 9804051 A MX9804051 A MX 9804051A MX 9804051 A MX9804051 A MX 9804051A MX 9804051 A MX9804051 A MX 9804051A
Authority
MX
Mexico
Prior art keywords
compositions
enzymatic method
blood
hemorrhagic blood
vitreous humor
Prior art date
Application number
MX9804051A
Other languages
English (en)
Inventor
Hampar L Karageozian
Vicken H Karageozian
Maria C Kenney
Jose L G Flores
Gabriel A C Aragon
Anthony B Nesburn
Original Assignee
Advanced Corneal Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Corneal Systems Inc filed Critical Advanced Corneal Systems Inc
Publication of MX9804051A publication Critical patent/MX9804051A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

Una preparacion de hialuronidasa libre de timerosal en donde la enzima hialuronidasa preferida carece de fracciones de peso molecular abajo de 40,000, entre 60-70,000, y arriba de 100,000. También se describe un método para acelerar la limpieza de la sangre hemorrágica del humor vítreo del ojo, el método comprende poner en contacto al menos una enzima de limpieza de hemorragia (por ejemplo, beta-glucoronidasa, metaloproteínasa de matriz, condroitinasa, condroitin sulfatasa, o protein quinasa) con el humor vítreo en una cantidad la cual es efectiva para provocar la limpieza acelerada de la sangre a partir de los mismos.
MX9804051A 1995-11-22 1998-05-21 Metodo enzimatico y composiciones para tratar la sangre hemorragica intravitrea. MX9804051A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/561,636 US5866120A (en) 1995-11-22 1995-11-22 Method for accelerating clearance of hemorrhagic blood from the vitreous humor with hyaluronidase

Publications (1)

Publication Number Publication Date
MX9804051A true MX9804051A (es) 1998-12-31

Family

ID=24242789

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9804051A MX9804051A (es) 1995-11-22 1998-05-21 Metodo enzimatico y composiciones para tratar la sangre hemorragica intravitrea.

Country Status (15)

Country Link
US (5) US5866120A (es)
EP (1) EP0862456B1 (es)
JP (1) JP2000502325A (es)
KR (1) KR100463009B1 (es)
CN (1) CN1207684A (es)
AT (1) ATE298584T1 (es)
AU (1) AU1407097A (es)
BR (1) BR9611617A (es)
CA (1) CA2238360C (es)
DE (1) DE69634903T2 (es)
DK (1) DK0862456T3 (es)
ES (1) ES2245458T3 (es)
MX (1) MX9804051A (es)
PT (1) PT862456E (es)
WO (1) WO1997018835A1 (es)

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US8784896B2 (en) 2012-09-17 2014-07-22 Biopep Solutions, Inc Antioxidant therapy with a whole, leech saliva extract
KR101454646B1 (ko) 2012-11-05 2014-10-27 (주)한국비엠아이 히알루로니다아제의 안정화 제제 및 이를 포함하는 액상제제
US20140212404A1 (en) * 2012-11-14 2014-07-31 Khizer Khaderi Compositions and Methods for Treating Injuries to the Visual System of a Human
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Also Published As

Publication number Publication date
JP2000502325A (ja) 2000-02-29
CA2238360A1 (en) 1997-05-29
EP0862456B1 (en) 2005-06-29
US6939542B2 (en) 2005-09-06
US5866120A (en) 1999-02-02
CA2238360C (en) 2009-09-01
AU1407097A (en) 1997-06-11
ES2245458T3 (es) 2006-01-01
KR100463009B1 (ko) 2005-02-28
DE69634903T2 (de) 2006-05-18
US20020071837A1 (en) 2002-06-13
PT862456E (pt) 2005-11-30
US6551590B2 (en) 2003-04-22
US6039943A (en) 2000-03-21
KR19990071565A (ko) 1999-09-27
US20060034822A1 (en) 2006-02-16
CN1207684A (zh) 1999-02-10
US20030129182A1 (en) 2003-07-10
EP0862456A1 (en) 1998-09-09
WO1997018835A1 (en) 1997-05-29
ATE298584T1 (de) 2005-07-15
DK0862456T3 (da) 2005-10-17
BR9611617A (pt) 1999-04-06
EP0862456A4 (en) 2003-02-12
DE69634903D1 (de) 2005-08-04

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