DE69633399D1 - Verlängerte freisetzung von gm-csf - Google Patents
Verlängerte freisetzung von gm-csfInfo
- Publication number
- DE69633399D1 DE69633399D1 DE69633399T DE69633399T DE69633399D1 DE 69633399 D1 DE69633399 D1 DE 69633399D1 DE 69633399 T DE69633399 T DE 69633399T DE 69633399 T DE69633399 T DE 69633399T DE 69633399 D1 DE69633399 D1 DE 69633399D1
- Authority
- DE
- Germany
- Prior art keywords
- csf
- extended release
- hydrogel
- microparticle
- crosslinked
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2989—Microcapsule with solid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Package Frames And Binding Bands (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US542445 | 1995-10-12 | ||
US08/542,445 US5942253A (en) | 1995-10-12 | 1995-10-12 | Prolonged release of GM-CSF |
PCT/US1996/016277 WO1997013502A2 (en) | 1995-10-12 | 1996-10-10 | Prolonged release of gm-csf |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69633399D1 true DE69633399D1 (de) | 2004-10-21 |
DE69633399T2 DE69633399T2 (de) | 2005-10-27 |
Family
ID=24163868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69633399T Expired - Fee Related DE69633399T2 (de) | 1995-10-12 | 1996-10-10 | Verlängerte freisetzung von gm-csf |
Country Status (10)
Country | Link |
---|---|
US (3) | US5942253A (de) |
EP (2) | EP1350518A1 (de) |
JP (2) | JPH11513667A (de) |
AT (1) | ATE275941T1 (de) |
AU (1) | AU714074B2 (de) |
DE (1) | DE69633399T2 (de) |
DK (1) | DK0859601T3 (de) |
ES (1) | ES2229286T3 (de) |
PT (1) | PT859601E (de) |
WO (1) | WO1997013502A2 (de) |
Families Citing this family (112)
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WO1997044016A1 (en) * | 1996-05-23 | 1997-11-27 | Samyang Corporation | Locally administrable, biodegradable and sustained-release pharmaceutical composition for periodontitis and process for preparation thereof |
KR0181252B1 (ko) * | 1996-12-31 | 1999-03-20 | 박원훈 | 에멀젼 방법에 의한 다공성 매트릭스형 서방성 제제의 제조방법 |
US20040096422A1 (en) * | 1997-06-17 | 2004-05-20 | Schwartz Herbert E. | Compositions of polyacids and polyethers and methods for their use in reducing pain |
US7192984B2 (en) * | 1997-06-17 | 2007-03-20 | Fziomed, Inc. | Compositions of polyacids and polyethers and methods for their use as dermal fillers |
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ES2248914T3 (es) * | 1997-08-29 | 2006-03-16 | Corixa Corporation | Agentes bioactivos encapsulados de liberacion rapida que permiten inducir o potenciar una respuesta inmunitaria y metodos para utilizar los mismos. |
ES2373861T3 (es) | 1997-09-18 | 2012-02-09 | Pacira Pharmaceuticals, Inc. | Composiciones anestésicas liposomiales de liberación sostenida. |
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-
1995
- 1995-10-12 US US08/542,445 patent/US5942253A/en not_active Expired - Fee Related
-
1996
- 1996-10-10 AU AU74384/96A patent/AU714074B2/en not_active Ceased
- 1996-10-10 JP JP9515216A patent/JPH11513667A/ja not_active Ceased
- 1996-10-10 EP EP03075970A patent/EP1350518A1/de not_active Withdrawn
- 1996-10-10 DE DE69633399T patent/DE69633399T2/de not_active Expired - Fee Related
- 1996-10-10 ES ES96936356T patent/ES2229286T3/es not_active Expired - Lifetime
- 1996-10-10 EP EP96936356A patent/EP0859601B1/de not_active Expired - Lifetime
- 1996-10-10 DK DK96936356T patent/DK0859601T3/da active
- 1996-10-10 AT AT96936356T patent/ATE275941T1/de not_active IP Right Cessation
- 1996-10-10 PT PT96936356T patent/PT859601E/pt unknown
- 1996-10-10 WO PCT/US1996/016277 patent/WO1997013502A2/en active IP Right Grant
-
1998
- 1998-11-03 US US09/185,213 patent/US6120807A/en not_active Expired - Fee Related
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1999
- 1999-11-17 US US09/442,370 patent/US6274175B1/en not_active Expired - Fee Related
-
2007
- 2007-05-25 JP JP2007139387A patent/JP2007308500A/ja active Pending
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EP0859601A2 (de) | 1998-08-26 |
EP0859601B1 (de) | 2004-09-15 |
US6120807A (en) | 2000-09-19 |
AU714074B2 (en) | 1999-12-16 |
US6274175B1 (en) | 2001-08-14 |
JP2007308500A (ja) | 2007-11-29 |
ATE275941T1 (de) | 2004-10-15 |
JPH11513667A (ja) | 1999-11-24 |
DK0859601T3 (da) | 2005-01-24 |
AU7438496A (en) | 1997-04-30 |
ES2229286T3 (es) | 2005-04-16 |
WO1997013502A3 (en) | 1997-10-02 |
EP1350518A1 (de) | 2003-10-08 |
WO1997013502A2 (en) | 1997-04-17 |
US5942253A (en) | 1999-08-24 |
DE69633399T2 (de) | 2005-10-27 |
PT859601E (pt) | 2005-02-28 |
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