DE69631174D1 - Wasserlösliche vitaminzubereitung, zur herstellung ausgezeichneter tabletten undverfahren zu deren herstellung - Google Patents
Wasserlösliche vitaminzubereitung, zur herstellung ausgezeichneter tabletten undverfahren zu deren herstellungInfo
- Publication number
- DE69631174D1 DE69631174D1 DE69631174T DE69631174T DE69631174D1 DE 69631174 D1 DE69631174 D1 DE 69631174D1 DE 69631174 T DE69631174 T DE 69631174T DE 69631174 T DE69631174 T DE 69631174T DE 69631174 D1 DE69631174 D1 DE 69631174D1
- Authority
- DE
- Germany
- Prior art keywords
- production
- water
- pct
- soluble vitamin
- date mar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23494096A JP4098376B2 (ja) | 1996-09-05 | 1996-09-05 | 錠剤特性の優れた水溶性ビタミン組成物およびその製造法 |
JP23494096 | 1996-09-05 | ||
PCT/JP1996/003079 WO1998009624A1 (fr) | 1996-09-05 | 1996-10-23 | Composition vitaminique hydrosoluble fournissant de remarquables comprimes et technique de production |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69631174D1 true DE69631174D1 (de) | 2004-01-29 |
DE69631174T2 DE69631174T2 (de) | 2004-09-02 |
Family
ID=16978662
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69631174T Expired - Fee Related DE69631174T2 (de) | 1996-09-05 | 1996-10-23 | Wasserlösliche vitaminzubereitung, zur herstellung ausgezeichneter tabletten undverfahren zu deren herstellung |
Country Status (12)
Country | Link |
---|---|
US (1) | US5994324A (de) |
EP (1) | EP0974355B1 (de) |
JP (1) | JP4098376B2 (de) |
KR (1) | KR100441114B1 (de) |
CN (1) | CN1229356A (de) |
AT (1) | ATE256462T1 (de) |
AU (1) | AU7335696A (de) |
DE (1) | DE69631174T2 (de) |
DK (1) | DK0974355T3 (de) |
ES (1) | ES2213182T3 (de) |
PT (1) | PT974355E (de) |
WO (1) | WO1998009624A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3419729B2 (ja) * | 2000-03-16 | 2003-06-23 | 株式会社ファンケル | 錠剤およびその製造方法 |
US6767899B1 (en) * | 2000-08-29 | 2004-07-27 | Leiner Health Services Corp. | Composition and method for treatment of conditions having an inflammatory component |
JP4886107B2 (ja) * | 2000-10-13 | 2012-02-29 | サンスター株式会社 | 歯周病予防用口腔内溶解錠 |
DE60225560T2 (de) * | 2001-07-30 | 2009-04-02 | Dsm Ip Assets B.V. | Zusammensetzung enthaltend epigallocatechin-gallat |
JP3980851B2 (ja) * | 2001-08-30 | 2007-09-26 | 有限会社ゴトーコーポレーション | 固型製剤、その製造方法、及び食品 |
KR100439979B1 (ko) * | 2001-11-06 | 2004-07-12 | 샘즈바이오 주식회사 | 이중 코팅된 순수 비타민-씨 및 그를 함유하는 화장료 조성물과 화장료 조성물 제조방법 |
CA2470495A1 (en) * | 2001-12-24 | 2003-07-17 | Teva Pharmaceutical Industries Ltd. | Dosage form with a core tablet of active ingredient sheathed in a compressed annular body of powder or granular material, and process and tooling for producing it |
US20040052843A1 (en) * | 2001-12-24 | 2004-03-18 | Lerner E. Itzhak | Controlled release dosage forms |
WO2005099681A1 (ja) * | 2004-04-14 | 2005-10-27 | Kyowa Hakko Kogyo Co., Ltd. | 分岐鎖アミノ酸を含有する錠剤およびその製造方法 |
CN100431515C (zh) * | 2005-05-24 | 2008-11-12 | 浙江大学 | 稳定微粒化药物添加剂的制备方法 |
FR2898056B1 (fr) | 2006-03-01 | 2012-01-20 | Ethypharm Sa | Comprimes resistant a l'ecrasement destines a eviter le detournement illicite |
WO2008046799A2 (de) * | 2006-10-20 | 2008-04-24 | Basf Aktiengesellschaft | Preparation of granules of hydrophilic vitamins |
JP2010024181A (ja) * | 2008-07-18 | 2010-02-04 | Takeda Chem Ind Ltd | 固形製剤及びその製造方法 |
JP5733930B2 (ja) * | 2009-09-09 | 2015-06-10 | 武田薬品工業株式会社 | 固形製剤 |
MX337603B (es) * | 2009-11-30 | 2016-03-10 | Adare Pharmaceuticals Inc | Composiciones y tabletas farmaceuticas con recubrimiento compresible y metodos de fabricacion. |
AU2012222861A1 (en) | 2011-02-28 | 2013-10-17 | Monash University | Binder powders |
CN107772478A (zh) * | 2016-08-24 | 2018-03-09 | 南京逐陆医药科技有限公司 | 一种复合维生素片及其制备方法 |
CN113974171A (zh) * | 2021-11-08 | 2022-01-28 | 北京素维生物科技有限公司 | 一种微水快溶组合物、微水快溶食品或药品以及其制备方法 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3293132A (en) * | 1963-03-25 | 1966-12-20 | Merck & Co Inc | Spray dried vitamin compositions and method of preparation |
ZA739588B (en) * | 1973-01-18 | 1974-11-27 | Hoffmann La Roche | Stabilized powder |
JPS5114522A (en) * | 1974-07-26 | 1976-02-05 | Komatsu Mfg Co Ltd | Kakyuenjinno kyufukajihaikishokukaizensochi |
NL184308C (nl) * | 1975-07-24 | 1989-06-16 | Takeda Chemical Industries Ltd | Werkwijze voor het bereiden van l-ascorbienzuurgranules. |
JPS58403B2 (ja) * | 1975-07-24 | 1983-01-06 | 武田薬品工業株式会社 | L− アスコルビンサンセイザイノ セイゾウホウ |
DE2706660A1 (de) * | 1977-02-17 | 1978-08-24 | Merck Patent Gmbh | Ascorbinsaeure enthaltende granulate und verfahren zu ihrer herstellung |
JPS5555112A (en) * | 1978-10-19 | 1980-04-22 | Sumitomo Chem Co Ltd | Preparation of biotin preparation rapidly soluble in water |
JPS5749143A (en) * | 1980-09-09 | 1982-03-20 | Matsushita Electric Works Ltd | Circuit breaker |
JPS5759803A (en) * | 1980-09-30 | 1982-04-10 | Takeda Chem Ind Ltd | Granule of l-sodium ascorbate, its preparation, and tablet comprising it |
JPS5879917A (ja) * | 1981-11-09 | 1983-05-13 | Showa Denko Kk | グリシン錠剤の成形方法 |
JPS61500435A (ja) * | 1983-10-24 | 1986-03-13 | バスフ・コーポレーション | 水溶性ビタミンを含有する噴霧乾燥された粉末及びこの方法により製造された粉末 |
JPH0753663B2 (ja) * | 1984-10-09 | 1995-06-07 | 武田薬品工業株式会社 | チアミン塩の顆粒,その製造法および錠剤 |
DE3447422A1 (de) * | 1984-12-24 | 1986-06-26 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von ascorbinsaeure-granulat |
AU587863B2 (en) * | 1985-10-07 | 1989-08-31 | Basf Aktiengesellschaft | Vitamin-containing granules and production thereof |
JPH0761961B2 (ja) * | 1986-06-24 | 1995-07-05 | 信越化学工業株式会社 | 被覆薬剤の製造方法 |
JPH01165519A (ja) * | 1987-12-22 | 1989-06-29 | Ohara Kako Kk | 水溶性及び/又は脂溶性ビタミン粒状製剤及びその製造方法 |
JPH01296953A (ja) * | 1988-05-24 | 1989-11-30 | Freunt Ind Co Ltd | ビタミンc組成物、それを添加した飼料およびその製造方法 |
JP2880243B2 (ja) * | 1989-04-18 | 1999-04-05 | 武田薬品工業株式会社 | アスコルビン酸カルシウム造粒物 |
JPH02282323A (ja) * | 1989-04-21 | 1990-11-19 | Shin Etsu Chem Co Ltd | 徐放性錠剤の製造方法 |
DE69001003T2 (de) * | 1989-08-31 | 1993-06-17 | Takeda Chemical Industries Ltd | Vitamin-b12-zusammensetzung. |
US5236920A (en) * | 1990-04-30 | 1993-08-17 | Basf Corporation | Granulated riboflavin product having high flowability, high riboflavin content |
US5254551A (en) * | 1990-04-30 | 1993-10-19 | Kirk Paula S | Flour fortification formulation comprising granulated riboflavin |
US5000888A (en) * | 1990-05-23 | 1991-03-19 | Basf Corporation | Process for spray drying riboflavin to produce a granulate product having low binder content |
JP3119801B2 (ja) * | 1995-09-28 | 2000-12-25 | 武田薬品工業株式会社 | ビタミン含有組成物の安定化方法 |
-
1996
- 1996-09-05 JP JP23494096A patent/JP4098376B2/ja not_active Expired - Fee Related
- 1996-10-23 AT AT96935410T patent/ATE256462T1/de not_active IP Right Cessation
- 1996-10-23 WO PCT/JP1996/003079 patent/WO1998009624A1/ja active IP Right Grant
- 1996-10-23 DE DE69631174T patent/DE69631174T2/de not_active Expired - Fee Related
- 1996-10-23 DK DK96935410T patent/DK0974355T3/da active
- 1996-10-23 CN CN96180429A patent/CN1229356A/zh active Pending
- 1996-10-23 US US08/793,748 patent/US5994324A/en not_active Expired - Fee Related
- 1996-10-23 KR KR10-1999-7000992A patent/KR100441114B1/ko not_active IP Right Cessation
- 1996-10-23 ES ES96935410T patent/ES2213182T3/es not_active Expired - Lifetime
- 1996-10-23 PT PT96935410T patent/PT974355E/pt unknown
- 1996-10-23 AU AU73356/96A patent/AU7335696A/en not_active Abandoned
- 1996-10-23 EP EP96935410A patent/EP0974355B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5994324A (en) | 1999-11-30 |
KR20000029837A (ko) | 2000-05-25 |
AU7335696A (en) | 1998-03-26 |
WO1998009624A1 (fr) | 1998-03-12 |
JPH1077224A (ja) | 1998-03-24 |
DE69631174T2 (de) | 2004-09-02 |
ATE256462T1 (de) | 2004-01-15 |
EP0974355A1 (de) | 2000-01-26 |
CN1229356A (zh) | 1999-09-22 |
ES2213182T3 (es) | 2004-08-16 |
EP0974355A4 (de) | 2000-12-20 |
PT974355E (pt) | 2004-04-30 |
DK0974355T3 (da) | 2004-04-19 |
KR100441114B1 (ko) | 2004-07-19 |
EP0974355B1 (de) | 2003-12-17 |
JP4098376B2 (ja) | 2008-06-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: BASF SE, 67063 LUDWIGSHAFEN, DE |
|
8339 | Ceased/non-payment of the annual fee |