DE69524865D1 - Vorrichtung zur dosierten inhalierung - Google Patents

Vorrichtung zur dosierten inhalierung

Info

Publication number
DE69524865D1
DE69524865D1 DE69524865T DE69524865T DE69524865D1 DE 69524865 D1 DE69524865 D1 DE 69524865D1 DE 69524865 T DE69524865 T DE 69524865T DE 69524865 T DE69524865 T DE 69524865T DE 69524865 D1 DE69524865 D1 DE 69524865D1
Authority
DE
Germany
Prior art keywords
inhalation
inhaler
indicate
counting means
metered dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69524865T
Other languages
English (en)
Other versions
DE69524865T2 (de
Inventor
R Jewett
A Ebeling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IEP Pharmaceutical Devices LLC
Original Assignee
IEP Pharmaceutical Devices LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IEP Pharmaceutical Devices LLC filed Critical IEP Pharmaceutical Devices LLC
Publication of DE69524865D1 publication Critical patent/DE69524865D1/de
Application granted granted Critical
Publication of DE69524865T2 publication Critical patent/DE69524865T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008Electronic counters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • A61M15/0093Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • B05B11/1073Springs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3306Optical measuring means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1028Pumps having a pumping chamber with a deformable wall
    • HELECTRICITY
    • H03ELECTRONIC CIRCUITRY
    • H03KPULSE TECHNIQUE
    • H03K17/00Electronic switching or gating, i.e. not by contact-making and –breaking
    • H03K17/94Electronic switching or gating, i.e. not by contact-making and –breaking characterised by the way in which the control signals are generated
    • H03K17/945Proximity switches
    • H03K17/955Proximity switches using a capacitive detector
DE69524865T 1994-11-29 1995-11-14 Vorrichtung zur dosierten inhalierung Expired - Lifetime DE69524865T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/346,524 US5544647A (en) 1994-11-29 1994-11-29 Metered dose inhalator
PCT/US1995/014759 WO1996016686A1 (en) 1994-11-29 1995-11-14 Metered dose inhaler

Publications (2)

Publication Number Publication Date
DE69524865D1 true DE69524865D1 (de) 2002-02-07
DE69524865T2 DE69524865T2 (de) 2002-08-29

Family

ID=23359809

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69524865T Expired - Lifetime DE69524865T2 (de) 1994-11-29 1995-11-14 Vorrichtung zur dosierten inhalierung

Country Status (13)

Country Link
US (1) US5544647A (de)
EP (1) EP0746366B1 (de)
JP (1) JP3307946B2 (de)
AT (1) ATE211399T1 (de)
AU (1) AU687290B2 (de)
CA (1) CA2181789C (de)
DE (1) DE69524865T2 (de)
ES (1) ES2170814T3 (de)
NO (1) NO316356B1 (de)
NZ (1) NZ297246A (de)
TW (1) TW294599B (de)
WO (1) WO1996016686A1 (de)
ZA (1) ZA9510129B (de)

Families Citing this family (187)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622163A (en) * 1994-11-29 1997-04-22 Iep Group, Inc. Counter for fluid dispensers
US6029659A (en) * 1995-04-17 2000-02-29 Solar Shield Corporation Inhalation device with counter
US5809997A (en) * 1995-05-18 1998-09-22 Medtrac Technologies, Inc. Electronic medication chronolog device
US5823179A (en) 1996-02-13 1998-10-20 1263152 Ontario Inc. Nebulizer apparatus and method
SE9701750D0 (sv) * 1997-05-12 1997-05-12 Astra Pharma Prod Inhalation device and method of manufacture thereof
TW533865U (en) 1997-06-10 2003-05-21 Glaxo Group Ltd Dispenser for dispensing medicament and actuation indicating device
US6142339A (en) 1998-01-16 2000-11-07 1263152 Ontario Inc. Aerosol dispensing device
JP4423457B2 (ja) 1998-01-16 2010-03-03 トルーデル メディカル インターナショナル ディスペンサおよび投与装置用表示装置
SE9801122D0 (sv) * 1998-03-30 1998-03-30 Astra Ab Inhalation device
SE9801115D0 (sv) * 1998-03-30 1998-03-30 Astra Ab Electrical device
US6729330B2 (en) 1998-05-05 2004-05-04 Trudell Medical International Indicating device for aerosol container
US6336453B1 (en) 1999-04-30 2002-01-08 Trudell Medical International Indicating device for aerosol container
US6082358A (en) 1998-05-05 2000-07-04 1263152 Ontario Inc. Indicating device for aerosol container
US6260549B1 (en) * 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
DE29814647U1 (de) * 1998-08-14 1999-12-23 Wischerath Josef Gmbh Co Kg Inhalator mit einer Dosierzähleinrichtung
ATE309021T1 (de) * 1998-08-28 2005-11-15 Glaxo Group Ltd Spender
US6397838B1 (en) * 1998-12-23 2002-06-04 Battelle Pulmonary Therapeutics, Inc. Pulmonary aerosol delivery device and method
GB9901988D0 (en) * 1999-01-30 1999-03-17 Glaxo Group Ltd Dispenser
US6116234A (en) * 1999-02-01 2000-09-12 Iep Pharmaceutical Devices Inc. Metered dose inhaler agitator
CN1144744C (zh) * 1999-10-16 2004-04-07 葛兰素集团有限公司 用于气雾剂容器的装置壳体
DE19961300A1 (de) * 1999-12-18 2001-06-21 Asta Medica Ag Vorratssystem für Arzneimittel in Pulverform und damit ausgestatteter Inhalator
GB0003839D0 (en) * 2000-02-19 2000-04-05 Glaxo Group Ltd Housing for an inhaler
PL204106B1 (pl) 2000-02-28 2009-12-31 Pharmakodex Ltd Zestaw do dostarczania środka terapeutycznego
AU2001249380A1 (en) 2000-03-22 2001-11-07 Chiron Corporation Compositions and methods for generating an immune response utilizing alphavirus-based vector systems
US6328035B1 (en) 2000-05-09 2001-12-11 Iep Pharmaceutical Devices Inc. Pneumatic breath actuated inhaler
TWI224512B (en) * 2000-06-23 2004-12-01 Norton Healthcare Ltd Reservoir pressure system for medicament inhaler
GB0026646D0 (en) 2000-10-31 2000-12-13 Glaxo Group Ltd Medicament dispenser
DE10065160A1 (de) * 2000-12-23 2002-06-27 Pfeiffer Erich Gmbh & Co Kg Vorrichtung zum Erfassen der Betätigung eines Spenders und Spender
EP1357965B1 (de) 2001-01-25 2014-09-24 Clinical Designs Limited Abgabevorrichtung für medikament
CA2809180C (en) * 2001-03-20 2015-06-02 Trudell Medical International Nebulizer apparatus with an adjustable fluid orifice
US6745760B2 (en) 2001-05-15 2004-06-08 Trudell Medical International Medicament applicator
US6994083B2 (en) * 2001-12-21 2006-02-07 Trudell Medical International Nebulizer apparatus and method
US7258118B2 (en) * 2002-01-24 2007-08-21 Sofotec Gmbh & Co, Kg Pharmaceutical powder cartridge, and inhaler equipped with same
US6651844B2 (en) 2002-02-22 2003-11-25 Schering Corporation Spray dispenser counter
US6820612B2 (en) 2002-03-21 2004-11-23 Robin Harabin Inhaler holster
US7004164B2 (en) 2002-03-21 2006-02-28 Trudell Medical International Indicating device for aerosol container
CA2479145C (en) 2002-03-22 2011-06-14 Clinical Designs Limited Medication dispenser with consistent dispensing
US20030235538A1 (en) * 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
GB0209531D0 (en) * 2002-04-26 2002-06-05 Glaxo Group Ltd Medicament dispenser
US20030205226A1 (en) 2002-05-02 2003-11-06 Pre Holding, Inc. Aerosol medication inhalation system
US6904908B2 (en) 2002-05-21 2005-06-14 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
GB0212896D0 (en) * 2002-06-05 2002-07-17 Trumeter Company Ltd Counter
CN1662930B (zh) 2002-06-21 2010-10-27 葛兰素集团有限公司 用于分配装置的动作指示器
GB0216831D0 (en) * 2002-07-19 2002-08-28 Glaxo Group Ltd Medicament dispenser
FR2844254B1 (fr) * 2002-09-10 2006-02-10 Valois Sa Valve de distribution de produit fluide et dispositif de distribution de produit fluide comportant une telle valve
FR2846308B1 (fr) * 2002-10-28 2006-02-10 Valois Sas Dispositif de distribution de produit fluide avec indicateur de dose
FR2846453B1 (fr) * 2002-10-28 2005-01-28 Valois Sas Dispositif d'affichage electronique et dispositif de distribution de produit fluide comportant un tel dispositif d'affichage
US20040221840A1 (en) * 2003-01-07 2004-11-11 Stockman-Lamb Melissa Soyna Inhaler
GB0301366D0 (en) * 2003-01-21 2003-02-19 Glaxo Group Ltd A fixation device
JP4805814B2 (ja) * 2003-03-04 2011-11-02 ノートン・ヘルスケアー リミテッド 内部医薬リザーバの状態を表すディスプレイを有する医薬分与装置
US7600512B2 (en) * 2003-07-14 2009-10-13 Vortran Medical Technology 1, Inc. Inhaler with breath actuated dose counter
US7703454B2 (en) * 2003-07-14 2010-04-27 Vortran Medical Technology Inhaler with breath actuated dose counter
US20050028815A1 (en) * 2003-07-23 2005-02-10 Deaton Daniel M. Apparatus for electronic dosage counter
GB0321296D0 (en) * 2003-09-11 2003-10-15 Trumeter Company Ltd Counting device
GB2406283B (en) * 2003-09-24 2006-04-05 Altana Pharma Ag Compliance monitor and method
US7621273B2 (en) 2003-10-28 2009-11-24 Trudell Medical International Indicating device with warning dosage indicator
SE0303570L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
WO2005053647A1 (en) * 2003-12-03 2005-06-16 Microdrug Ag Medical product containing tiotropium
SE0303269L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Medicinsk produkt
GB0328859D0 (en) 2003-12-12 2004-01-14 Clinical Designs Ltd Dispenser and counter
US7100530B2 (en) 2003-12-15 2006-09-05 Trudell Medical International, Inc. Dose indicating device
FR2864231B1 (fr) * 2003-12-19 2006-05-19 Valois Sas Dispositif de distribution de produit fluide
DE102004009435A1 (de) * 2004-02-24 2005-12-08 Boehringer Ingelheim International Gmbh Zerstäuber
GB2412593A (en) * 2004-03-02 2005-10-05 Rosti As Monitoring devices for inhaler valves
GB2411597A (en) * 2004-03-02 2005-09-07 Rosti As Medicament dispenser with valve actuation monitored using light
SE0401773D0 (sv) 2004-07-02 2004-07-02 Astrazeneca Ab An inhalation and a method for assemnling said inhalation device
SE0401786D0 (sv) 2004-07-05 2004-07-05 Astrazeneca Ab Inhaler device
MX2007000592A (es) * 2004-07-16 2008-03-04 Almirall Lab Inhalador para la administracion de farmaceuticos en polvo, y un sistema de cartuchos de polvo para uso con este inhalador.
US7543582B2 (en) 2004-09-20 2009-06-09 Trudell Medical International Dose indicating device with display elements attached to container
GB0425518D0 (en) 2004-11-19 2004-12-22 Clinical Designs Ltd Substance source
US7832394B2 (en) * 2004-12-22 2010-11-16 Schechter Alan M Apparatus for dispensing pressurized contents
GB0428204D0 (en) 2004-12-23 2005-01-26 Clinical Designs Ltd Medicament container
JP5189369B2 (ja) 2005-01-20 2013-04-24 トルーデル メディカル インターナショナル 分与装置
EP1843812A4 (de) 2005-02-01 2008-12-03 Intelliject Llc Vorrichtungen, systeme und verfahren zur medikamentenabgabe
US8206360B2 (en) * 2005-02-01 2012-06-26 Intelliject, Inc. Devices, systems and methods for medicament delivery
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
US8231573B2 (en) * 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
US7219664B2 (en) * 2005-04-28 2007-05-22 Kos Life Sciences, Inc. Breath actuated inhaler
CN101252964A (zh) * 2005-05-12 2008-08-27 科斯生命科学公司 用于定剂量的吸入器的剂量计数器
EP1888155A4 (de) * 2005-05-24 2012-08-22 Shl Group Ab Dosiszählvorrichtung für einen inhalator
US20060271011A1 (en) * 2005-05-25 2006-11-30 Mock Bradley D Methods and apparatus for indicating when a disposable component of a drug delivery system needs to be replaced
JP5295769B2 (ja) 2005-08-31 2013-09-18 ティツー・バイオシステムズ・インコーポレーテッド 分析物を検出するためのnmr装置
US20070095342A1 (en) * 2005-10-18 2007-05-03 Bijan Olfati Accessorized inhaler
EP1991295B1 (de) * 2006-03-03 2016-02-10 3M Innovative Properties Company Vorrichtung zur abgemessenen und dosierten ausgabe
JP4969300B2 (ja) * 2006-05-18 2012-07-04 英夫 吉田 消火ガス噴射器
WO2008008281A2 (en) 2006-07-07 2008-01-17 Proteus Biomedical, Inc. Smart parenteral administration system
DE102006036962A1 (de) * 2006-08-01 2008-02-14 Ing. Erich Pfeiffer Gmbh Dosiervorrichtung für ein Medium
US8141550B2 (en) 2006-08-01 2012-03-27 Trudell Medical International Dispensing device
WO2008067254A2 (en) * 2006-11-27 2008-06-05 Abbott Respiratory Llc Nasal drug delivery device and method
EP2099514A2 (de) * 2006-12-22 2009-09-16 Schering Corporation Dosenzählmechanismus
WO2008091838A2 (en) 2007-01-22 2008-07-31 Intelliject, Inc. Medical injector with compliance tracking and monitoring
US20080210231A1 (en) * 2007-01-31 2008-09-04 Abbott Laboratories Metered dose inhaler cleaning method and apparatus
US20100199984A1 (en) * 2007-04-02 2010-08-12 Abbott Laboratories Breath actuated nasal pump
WO2008157329A1 (en) 2007-06-15 2008-12-24 Michael Spandorfer A drug delivery and monitoring system for a ventilator
US9125979B2 (en) 2007-10-25 2015-09-08 Proteus Digital Health, Inc. Fluid transfer port information system
EP2534957B1 (de) 2007-12-14 2015-05-27 AeroDesigns, Inc Abgabe von Aerosol-sprühbaren Produkten
US9550031B2 (en) 2008-02-01 2017-01-24 Reciprocal Labs Corporation Device and method to monitor, track, map, and analyze usage of metered-dose inhalers in real-time
US8082873B2 (en) 2008-05-05 2011-12-27 Trudell Medical International Drive mechanism for an indicating device
US8021344B2 (en) 2008-07-28 2011-09-20 Intelliject, Inc. Medicament delivery device configured to produce an audible output
USD994111S1 (en) 2008-05-12 2023-08-01 Kaleo, Inc. Medicament delivery device cover
JP4892519B2 (ja) * 2008-05-20 2012-03-07 シャープ株式会社 積層型電子写真感光体およびそれを備えた画像形成装置
US8181591B1 (en) 2008-05-23 2012-05-22 Trudell Medical International Domed actuator for indicating device
CA2683353C (en) 2008-10-22 2015-12-15 Trudell Medical International Modular aerosol delivery system
US8381719B1 (en) 2008-12-22 2013-02-26 Trudell Medical International Medicament delivery system with dose indicator and oversleeve actuator
NZ574666A (en) * 2009-02-05 2009-04-30 Nexus6 Ltd A medicament inhaler holder that uses optical means to count and display the number of doses used
GB0904040D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
GB0904059D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
GB2469068B (en) * 2009-03-31 2011-03-09 Naseem Bari Usage indicator
NZ575943A (en) * 2009-04-01 2009-07-31 Nexus6 Ltd Improvements in or Relating to Medicament Delivery Devices
US20110031038A1 (en) * 2009-08-07 2011-02-10 Sagatulo, Inc. Method and device for indicating doses in a drug delivery system
US8539945B2 (en) 2009-08-18 2013-09-24 Teva Pharmaceutical Industries Ltd. Dose counter and recording method
AU2010324997A1 (en) 2009-11-24 2012-05-31 Gilead Sciences, Inc. Inhaled fosfomycin/tobramycin for the treatment of chronic obstructive pulmonary disease
WO2011081937A1 (en) 2009-12-15 2011-07-07 Gilead Sciences, Inc. Corticosteroid-beta-agonist-muscarinic antagonist compounds for use in therapy
JP5841951B2 (ja) 2010-02-01 2016-01-13 プロテウス デジタル ヘルス, インコーポレイテッド データ収集システム
CN102905612A (zh) 2010-02-01 2013-01-30 普罗秋斯数字健康公司 双腕式数据采集系统
UY33373A (es) 2010-05-10 2011-12-30 Gilead Sciences Inc ?Compuestos de pirazolopiridina bifuncionales, su uso en terapia y composiciones que los comprenden?.
CA2796826A1 (en) 2010-05-10 2011-11-17 Gilead Sciences, Inc. Bifunctional quinoline derivatives
US8869793B1 (en) 2010-05-18 2014-10-28 Idtx Systems, Inc. Compact self-contained automated MDI adapters or units for ventilators
DE102010024912B4 (de) * 2010-06-15 2013-02-28 Aptar Radolfzell Gmbh Inhalationsvorrichtung
AU2011270798B2 (en) 2010-06-24 2015-03-19 Gilead Sciences, Inc. Pyrazolo [1, 5 -a] pyrimidines as antiviral agents
KR101821680B1 (ko) 2010-07-22 2018-01-24 길리애드 사이언시즈, 인코포레이티드 파라믹소비리대 바이러스 감염을 치료하기 위한 방법 및 화합물
TW201305185A (zh) 2010-09-13 2013-02-01 Gilead Sciences Inc 用於抗病毒治療之2’-氟取代之碳-核苷類似物
US8387617B1 (en) * 2010-09-15 2013-03-05 John H. Robinson Canister dosage indicator device
DE102010042007B4 (de) * 2010-10-05 2013-04-04 Aptar Radolfzell Gmbh Austragvorrichtung für pharmazeutische Medien
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
US9004063B1 (en) * 2011-08-17 2015-04-14 Shane M. Guldbransen Portable oxygen inhaler device
NZ595367A (en) * 2011-09-23 2012-02-24 Nexus6 Ltd A dose counting mechanism adapted to enclose a medicament delivery device
WO2013045996A1 (en) 2011-09-26 2013-04-04 Trudell Medical International Dose counter and medication delivery device
US9481704B2 (en) * 2012-03-13 2016-11-01 Gilead Sciences, Inc. 2′-substituted carba-nucleoside analogs for antiviral treatment
PT2838900T (pt) 2012-04-17 2019-11-15 Gilead Sciences Inc Compostos e métodos para tratamento antiviral
SG11201407867VA (en) 2012-05-29 2014-12-30 Parion Sciences Inc Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases
CA3176610A1 (en) 2012-06-25 2014-01-03 Gecko Health Innovations, Inc. Devices, systems, and methods for adherence monitoring and patient interaction
US9320800B2 (en) * 2012-08-15 2016-04-26 Wisconsin Alumni Research Foundation Methods and compositions for enhancing intranasal delivery of therapeutic agents
GB2505209A (en) * 2012-08-22 2014-02-26 Presspart Gmbh & Co Kg Metered-dose inhaler and counter
US9872964B2 (en) 2012-08-22 2018-01-23 Presspart Gmbh & Co. Kg Metered dose inhaler counter and metered-dose inhaler including such a counter
MX2015007797A (es) 2012-12-17 2015-10-05 Parion Sciences Inc Compuestos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil) carbamimidoil) pirazin-2-carboxamida.
RU2015129065A (ru) 2012-12-17 2017-01-25 Пэрион Сайенсиз, Инк. Производные хлор-пиразинкарбоксамида, обладающие активностью блокирования эпителиальных натриевых каналов
ES2674665T3 (es) 2012-12-17 2018-07-03 Parion Sciences, Inc. Compuestos de 3,5-diamino-6-cloro-N-(N-(4-fenilbutilo)carbamimidoilo)-pirazina-2-carboxamida
GB201223008D0 (en) * 2012-12-20 2013-01-30 Euro Celtique Sa Counter
WO2014106056A2 (en) 2012-12-27 2014-07-03 Kaleo, Inc. Devices, systems and methods for locating and interacting with medicament delivery systems
GB201310826D0 (en) * 2013-06-18 2013-07-31 Smiths Medical Int Ltd Respiratory therapy apparatus and methods
US8807131B1 (en) 2013-06-18 2014-08-19 Isonea Limited Compliance monitoring for asthma inhalers
EP3738633B1 (de) 2013-08-28 2021-07-28 Gecko Health Innovations, Inc. Vorrichtungen und systeme zur überwachung der einhaltung, vorrichtungen und systeme zur überwachung der verwendung von verbrauchsmittelspendern
USD771800S1 (en) * 2013-08-28 2016-11-15 Gecko Health Innovations, Inc. Inhaler cap
ES2834636T3 (es) 2013-08-30 2021-06-18 Adherium Nz Ltd Un monitor de cumplimiento para un inhalador de medicamento
UA119050C2 (uk) 2013-11-11 2019-04-25 Ґілеад Саєнсиз, Інк. ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ
DE102014206350B3 (de) * 2014-04-02 2015-05-21 Aptar Radolfzell Gmbh Pharmazeutischer Spender mit einer Erfassungseinrichtung
US10173025B2 (en) 2014-04-21 2019-01-08 Idtx Systems, Inc. Automated drug delivery systems
WO2015187471A1 (en) * 2014-06-04 2015-12-10 Merck Sharp & Dohme Corp. Dry powder inhaler with dose depletion evaluation
TWI678369B (zh) 2014-07-28 2019-12-01 美商基利科學股份有限公司 用於治療呼吸道合胞病毒感染之噻吩並[3,2-d]嘧啶、呋喃並[3,2-d]嘧啶及吡咯並[3,2-d]嘧啶化合物類
TWI673283B (zh) 2014-08-21 2019-10-01 美商基利科學股份有限公司 2’-氯胺基嘧啶酮及嘧啶二酮核苷類
USD798438S1 (en) 2014-08-27 2017-09-26 Gecko Health Innovations, Inc. Inhaler cap
EP3701988A1 (de) * 2014-08-28 2020-09-02 Norton (Waterford) Limited Einhaltungsunterstützendes modul für ein inhaliergerät
US10561814B2 (en) 2014-11-19 2020-02-18 Idtx Systems, Inc. Automated drug dispensing systems with automated HME bypass for ventilator circuits
TWM506609U (zh) 2015-05-27 2015-08-11 Ind Tech Res Inst 呼吸器之藥量監控裝置
US10255412B2 (en) 2015-11-13 2019-04-09 Reciprocal Labs Corporation Real time adaptive controller medication dosing
US20170173294A1 (en) 2015-12-16 2017-06-22 John H. Renaud Breathe Clear
US11519016B2 (en) 2016-01-21 2022-12-06 T2 Biosystems, Inc. NMR methods and systems for the rapid detection of bacteria
ES2966349T3 (es) 2016-05-19 2024-04-22 Trudell Medical Int Cámara de retención con válvula inteligente
US10786638B2 (en) 2016-07-08 2020-09-29 Trudell Medical International Nebulizer apparatus and method
EP3984579A1 (de) 2016-07-08 2022-04-20 Trudell Medical International Intelligente schwingende vorrichtung für positiven ausatmungsdruck
EP3506972A4 (de) * 2016-09-02 2020-04-22 Inspirx, Inc. Durch atem verstärkter düsenzerstäuber
MX2019006702A (es) 2016-12-09 2019-08-01 Trudell Medical Int Nebulizador inteligente.
EP3570906A4 (de) 2017-01-17 2020-10-21 Kaleo, Inc. Medikamentenabgabevorrichtungen mit drahtloser konnektivität und ereignisdetektion
ES2913089T3 (es) 2017-02-20 2022-05-31 Presspart Gmbh & Co Kg Inhalador dosificador
EP3641861A1 (de) * 2017-06-23 2020-04-29 Amgen Inc. Elektronische arzneimittelabgabevorrichtung mit einer durch eine schaltungsanordnung aktivierten kappe
EP3485930B1 (de) * 2017-11-20 2021-04-14 Presspart Gmbh & Co. Kg Inhalationssystem
CA3086890A1 (en) 2018-01-04 2019-07-11 Trudell Medical International Smart oscillating positive expiratory pressure device
US11804303B2 (en) 2018-03-01 2023-10-31 Reciprocal Labs Corporation Evaluation of respiratory disease risk in a geographic region based on medicament device monitoring
WO2020018433A1 (en) 2018-07-16 2020-01-23 Kaleo, Inc. Medicament delivery devices with wireless connectivity and compliance detection
EP3636348B1 (de) 2018-10-08 2023-01-04 Aptar Radolfzell GmbH Set aus einem pumpspender und einer auswerteeinheit
USD901671S1 (en) 2018-11-28 2020-11-10 Rpc Formatec Gmbh Inhaler
WO2021038467A1 (en) 2019-08-27 2021-03-04 Trudell Medical International Smart oscillating positive expiratory pressure device
IL294032A (en) 2019-12-24 2022-08-01 Carna Biosciences Inc Compounds that regulate diacylglycerol kinase
TWI794742B (zh) 2020-02-18 2023-03-01 美商基利科學股份有限公司 抗病毒化合物
KR20220143064A (ko) 2020-02-18 2022-10-24 길리애드 사이언시즈, 인코포레이티드 항바이러스 화합물
TW202245800A (zh) 2020-02-18 2022-12-01 美商基利科學股份有限公司 抗病毒化合物
TWI791193B (zh) 2020-02-18 2023-02-01 美商基利科學股份有限公司 抗病毒化合物
CR20220547A (es) 2020-05-01 2022-12-15 Gilead Sciences Inc Compuestos de 2,4-dioxopirimidina inhibidores de cd73
US11596579B2 (en) * 2020-09-03 2023-03-07 Amir Akbar Sadigh Behzadi Carriage with timer mechanism for holding a container
WO2022271650A1 (en) 2021-06-23 2022-12-29 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
CN117355531A (zh) 2021-06-23 2024-01-05 吉利德科学公司 二酰基甘油激酶调节化合物
KR20240025616A (ko) 2021-06-23 2024-02-27 길리애드 사이언시즈, 인코포레이티드 다이아실글리세롤 키나제 조절 화합물
KR20240023628A (ko) 2021-06-23 2024-02-22 길리애드 사이언시즈, 인코포레이티드 디아실글리세롤 키나제 조절 화합물
CA3225185A1 (en) * 2021-08-09 2023-02-16 Aisha McCain Acoustic dose meter
CA3235986A1 (en) 2021-10-29 2023-05-04 Gilead Science, Inc. Cd73 compounds

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4300548A (en) * 1978-04-26 1981-11-17 Airco, Inc. System for detecting position of gauge pointer
SE438261B (sv) * 1981-07-08 1985-04-15 Draco Ab Anvendning i dosinhalator av ett perforerat membran
NZ209900A (en) * 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
NZ219021A (en) * 1986-01-27 1989-06-28 Gea Farmaceutisk Fabrik As Inhaler: medicine discharged intermittently during each inhalation
US4947875A (en) * 1988-09-08 1990-08-14 R. J. Reynolds Tobacco Company Flavor delivery articles utilizing electrical energy
SE466684B (sv) * 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
US4955371A (en) * 1989-05-08 1990-09-11 Transtech Scientific, Inc. Disposable inhalation activated, aerosol device for pulmonary medicine
GB8924823D0 (en) * 1989-11-03 1989-12-20 Smith Kline French Lab Dosage inhalers
US5020527A (en) * 1990-02-20 1991-06-04 Texax-Glynn Corporation Inhaler device with counter/timer means
JP2593581B2 (ja) * 1990-11-06 1997-03-26 アルパイン株式会社 電磁波式近接センサ
US5224474A (en) * 1991-03-04 1993-07-06 Bloomfield John W Retrofitting gas mask voice amplifier unit with easily actuated switch means
US5394866A (en) * 1991-03-05 1995-03-07 Aradigm Corporation Automatic aerosol medication delivery system and methods
US5392768A (en) * 1991-03-05 1995-02-28 Aradigm Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
WO1992017231A1 (en) * 1991-03-28 1992-10-15 Innomed, Inc. Microelectronic inhaler having a counter and timer
US5363842A (en) * 1991-12-20 1994-11-15 Circadian, Inc. Intelligent inhaler providing feedback to both patient and medical professional
US5284133A (en) * 1992-07-23 1994-02-08 Armstrong Pharmaceuticals, Inc. Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means
US5564414A (en) * 1994-05-26 1996-10-15 Walker; William F. Pressurized and metered medication dose counter on removable sleeve

Also Published As

Publication number Publication date
NO963134L (no) 1996-08-28
CA2181789C (en) 2004-05-25
TW294599B (de) 1997-01-01
EP0746366A1 (de) 1996-12-11
NZ297246A (en) 1997-09-22
EP0746366B1 (de) 2002-01-02
AU687290B2 (en) 1998-02-19
AU4236096A (en) 1996-06-19
CA2181789A1 (en) 1996-06-06
WO1996016686A1 (en) 1996-06-06
DE69524865T2 (de) 2002-08-29
ATE211399T1 (de) 2002-01-15
NO963134D0 (no) 1996-07-26
EP0746366A4 (de) 1997-11-12
US5544647A (en) 1996-08-13
NO316356B1 (no) 2004-01-19
JP3307946B2 (ja) 2002-07-29
ES2170814T3 (es) 2002-08-16
ZA9510129B (en) 1996-06-06
JPH09508845A (ja) 1997-09-09

Similar Documents

Publication Publication Date Title
DE69524865D1 (de) Vorrichtung zur dosierten inhalierung
ATE223744T1 (de) Inhalator mit einer dosierzähleinrichtung
DE69503487D1 (de) Alleinstehender zähler für dosierinhalator
AU1215900A (en) Inhalation actuated device for use with metered dose inhalers (mdis)
ATE309019T1 (de) Vorrichtung zur anwendung mit dosierenden inhalatoren
GB2306891B (en) Casing and spirometer for metered dose inhaler
ATE207372T1 (de) Vorrichtung für inhalator
DK0503031T3 (da) Inhalator med et reservoir til flere doser af et materiale, der skal inhaleres
CA2149027A1 (en) Inhaler for multiple use
SE9700423D0 (sv) Disposable inhaler
EE03997B1 (et) Albuterooli doseeriv inhalaator
FI930845A0 (fi) Arbetsgasfri inhalationsapparat med sidoluftstroemning
ATE374054T1 (de) Atmungsbetätigter inhalator
EE9700372A (et) Beklometasoondipropionaadi doseeriv inhalaator
ATE270123T1 (de) Pneumatischer, durch atmung ausgelöster inhalator
ATE209516T1 (de) Medikamententräger für trockenpulverinhalator
EP1229953A4 (de) Atmungsgesteuerte vorrichtung zur verwendung mit dosierinhalatoren (mdi)
DE69503243T2 (de) Einsatz zur begrenzung einer dosierkammer eines inhalators
ATE103190T1 (de) Vorrichtung zur abgabe eines definierten atemgas- volumens.
IE802296L (en) Electronic dose indicator for inhalers
AR230009A1 (es) Un dispositivo dosificador de la proporcion de gases anestesicos en un vaporizador de anestesia
YU56592A (sh) Naprava za ispuštanje medikamenata
MX9701196A (es) Aparato inhalador con camara de optimizacion.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition