DE69522212T2 - Isosorbiddinitrat enthaltendes und unter verwendung einer adhäsiven mischung hergestelltes pflaster - Google Patents
Isosorbiddinitrat enthaltendes und unter verwendung einer adhäsiven mischung hergestelltes pflasterInfo
- Publication number
- DE69522212T2 DE69522212T2 DE69522212T DE69522212T DE69522212T2 DE 69522212 T2 DE69522212 T2 DE 69522212T2 DE 69522212 T DE69522212 T DE 69522212T DE 69522212 T DE69522212 T DE 69522212T DE 69522212 T2 DE69522212 T2 DE 69522212T2
- Authority
- DE
- Germany
- Prior art keywords
- adhesive
- isosorbide dinitrate
- layer
- based adhesive
- thickness
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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- 235000017281 sodium acetate Nutrition 0.000 description 1
- APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical compound [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 description 1
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- LLHSEQCZSNZLRI-UHFFFAOYSA-M sodium;3,5-bis(methoxycarbonyl)benzenesulfonate Chemical compound [Na+].COC(=O)C1=CC(C(=O)OC)=CC(S([O-])(=O)=O)=C1 LLHSEQCZSNZLRI-UHFFFAOYSA-M 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 229960002920 sorbitol Drugs 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000000859 sublimation Methods 0.000 description 1
- 230000008022 sublimation Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 238000005809 transesterification reaction Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000013585 weight reducing agent Substances 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2969994 | 1994-02-28 | ||
| PCT/JP1995/000318 WO1995022970A1 (fr) | 1994-02-28 | 1995-02-28 | Timbre renfermant du dinitrate d'isosorbide et etant prepare a l'aide d'un melange adhesif |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69522212D1 DE69522212D1 (de) | 2001-09-20 |
| DE69522212T2 true DE69522212T2 (de) | 2002-05-23 |
Family
ID=12283367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69522212T Expired - Fee Related DE69522212T2 (de) | 1994-02-28 | 1995-02-28 | Isosorbiddinitrat enthaltendes und unter verwendung einer adhäsiven mischung hergestelltes pflaster |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5762954A (ja) |
| EP (1) | EP0748626B1 (ja) |
| JP (1) | JP3162079B2 (ja) |
| KR (1) | KR100354499B1 (ja) |
| CN (1) | CN1144481A (ja) |
| AT (1) | ATE204166T1 (ja) |
| AU (1) | AU689225B2 (ja) |
| CA (1) | CA2184389A1 (ja) |
| DE (1) | DE69522212T2 (ja) |
| DK (1) | DK0748626T3 (ja) |
| ES (1) | ES2158937T3 (ja) |
| GR (1) | GR3037058T3 (ja) |
| NZ (1) | NZ281334A (ja) |
| PT (1) | PT748626E (ja) |
| WO (1) | WO1995022970A1 (ja) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1102384C (zh) | 1997-01-07 | 2003-03-05 | 帝人株式会社 | 含二硝酸异山梨酯的贴剂 |
| WO2000059483A2 (en) * | 1999-04-01 | 2000-10-12 | Alza Corporation | Transdermal drug delivery devices comprising a polyurethane drug reservoir |
| KR100439658B1 (ko) * | 2001-06-23 | 2004-07-12 | 제일약품주식회사 | 이소소르비드 디니트레이트를 활성성분으로 하는경피흡수제제 및 그 제조방법 |
| EA017580B1 (ru) * | 2008-02-15 | 2013-01-30 | Тоо "Казнаномед" | Способ увеличения периода полувыведения изосорбида динитрата при коронарной недостаточности |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4849226A (en) * | 1981-06-29 | 1989-07-18 | Alza Corporation | Method for increasing oxygen supply by administering vasodilator |
| JPS61100520A (ja) * | 1984-10-22 | 1986-05-19 | Sekisui Chem Co Ltd | 経皮投与型テ−プ状医薬品 |
| US4956181A (en) * | 1987-05-08 | 1990-09-11 | Eastman Kodak | Nitrate therapy for angina pectoris |
| US5300291A (en) * | 1988-03-04 | 1994-04-05 | Noven Pharmaceuticals, Inc. | Method and device for the release of drugs to the skin |
| US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| JP3064402B2 (ja) * | 1990-11-19 | 2000-07-12 | 森本 雍憲 | 硝酸イソソルビド含有貼付剤 |
| JP3197039B2 (ja) * | 1991-08-08 | 2001-08-13 | 積水化学工業株式会社 | テープ製剤 |
| JPH05156328A (ja) * | 1991-12-09 | 1993-06-22 | Nkk Corp | 高炉異常炉況解析装置 |
| JP3081413B2 (ja) * | 1993-06-03 | 2000-08-28 | 帝三製薬株式会社 | 混合系粘着剤を用いた硝酸イソソルビド含有貼付剤の製造方法 |
-
1995
- 1995-02-28 ES ES95910006T patent/ES2158937T3/es not_active Expired - Lifetime
- 1995-02-28 DK DK95910006T patent/DK0748626T3/da active
- 1995-02-28 PT PT95910006T patent/PT748626E/pt unknown
- 1995-02-28 EP EP95910006A patent/EP0748626B1/en not_active Expired - Lifetime
- 1995-02-28 CN CN95192319A patent/CN1144481A/zh active Pending
- 1995-02-28 WO PCT/JP1995/000318 patent/WO1995022970A1/ja active IP Right Grant
- 1995-02-28 AT AT95910006T patent/ATE204166T1/de not_active IP Right Cessation
- 1995-02-28 DE DE69522212T patent/DE69522212T2/de not_active Expired - Fee Related
- 1995-02-28 NZ NZ281334A patent/NZ281334A/xx unknown
- 1995-02-28 KR KR1019960704734A patent/KR100354499B1/ko not_active IP Right Cessation
- 1995-02-28 US US08/700,418 patent/US5762954A/en not_active Expired - Fee Related
- 1995-02-28 AU AU18247/95A patent/AU689225B2/en not_active Ceased
- 1995-02-28 JP JP52226395A patent/JP3162079B2/ja not_active Expired - Fee Related
- 1995-02-28 CA CA002184389A patent/CA2184389A1/en not_active Abandoned
-
2001
- 2001-10-30 GR GR20010401930T patent/GR3037058T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1144481A (zh) | 1997-03-05 |
| PT748626E (pt) | 2002-02-28 |
| AU1824795A (en) | 1995-09-11 |
| ES2158937T3 (es) | 2001-09-16 |
| DE69522212D1 (de) | 2001-09-20 |
| KR970701042A (ko) | 1997-03-17 |
| EP0748626A1 (en) | 1996-12-18 |
| DK0748626T3 (da) | 2001-10-08 |
| CA2184389A1 (en) | 1995-08-31 |
| AU689225B2 (en) | 1998-03-26 |
| JP3162079B2 (ja) | 2001-04-25 |
| GR3037058T3 (en) | 2002-01-31 |
| US5762954A (en) | 1998-06-09 |
| WO1995022970A1 (fr) | 1995-08-31 |
| EP0748626A4 (en) | 1997-11-12 |
| EP0748626B1 (en) | 2001-08-16 |
| ATE204166T1 (de) | 2001-09-15 |
| NZ281334A (en) | 1997-08-22 |
| KR100354499B1 (ko) | 2003-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |