DE69506857T2 - Mucoadhäsive emulsionen enthaltend cyclodextrine - Google Patents

Mucoadhäsive emulsionen enthaltend cyclodextrine

Info

Publication number
DE69506857T2
DE69506857T2 DE69506857T DE69506857T DE69506857T2 DE 69506857 T2 DE69506857 T2 DE 69506857T2 DE 69506857 T DE69506857 T DE 69506857T DE 69506857 T DE69506857 T DE 69506857T DE 69506857 T2 DE69506857 T2 DE 69506857T2
Authority
DE
Germany
Prior art keywords
emulsions containing
cyclodextrine
mucoadhesive
mucoadhesive emulsions
containing cyclodextrine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69506857T
Other languages
English (en)
Other versions
DE69506857D1 (de
Inventor
Peter Putteman
Marc Francois
Eric Snoeckx
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of DE69506857D1 publication Critical patent/DE69506857D1/de
Publication of DE69506857T2 publication Critical patent/DE69506857T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Inorganic Chemistry (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
  • Adhesives Or Adhesive Processes (AREA)
DE69506857T 1994-05-18 1995-05-10 Mucoadhäsive emulsionen enthaltend cyclodextrine Expired - Lifetime DE69506857T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94201402 1994-05-18
PCT/EP1995/001760 WO1995031178A1 (en) 1994-05-18 1995-05-10 Mucoadhesive emulsions containing cyclodextrin

Publications (2)

Publication Number Publication Date
DE69506857D1 DE69506857D1 (de) 1999-02-04
DE69506857T2 true DE69506857T2 (de) 1999-08-05

Family

ID=8216883

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69506857T Expired - Lifetime DE69506857T2 (de) 1994-05-18 1995-05-10 Mucoadhäsive emulsionen enthaltend cyclodextrine

Country Status (30)

Country Link
US (1) US5814330A (de)
EP (1) EP0759741B1 (de)
JP (1) JP3862748B2 (de)
KR (1) KR100369703B1 (de)
CN (1) CN1091590C (de)
AP (1) AP731A (de)
AT (1) ATE174790T1 (de)
AU (1) AU680767B2 (de)
BG (1) BG62754B1 (de)
BR (1) BR9507873A (de)
CZ (1) CZ285606B6 (de)
DE (1) DE69506857T2 (de)
DK (1) DK0759741T3 (de)
EE (1) EE03304B1 (de)
ES (1) ES2127529T3 (de)
FI (1) FI964589A (de)
HK (1) HK1010688A1 (de)
HU (1) HU218082B (de)
IL (1) IL113742A (de)
MY (1) MY113846A (de)
NO (1) NO309507B1 (de)
NZ (1) NZ285761A (de)
OA (1) OA10321A (de)
PL (1) PL179619B1 (de)
RO (1) RO117145B1 (de)
RU (1) RU2164418C2 (de)
SK (1) SK282623B6 (de)
TW (1) TW438601B (de)
WO (1) WO1995031178A1 (de)
ZA (1) ZA954023B (de)

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US6416779B1 (en) * 1997-06-11 2002-07-09 Umd, Inc. Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections
KR19990001564A (ko) * 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
ES2185238T3 (es) 1997-12-31 2003-04-16 Choongwae Pharma Corp Preparado oral de itraconazol y su procedimiento de preparacion.
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
NZ330726A (en) * 1998-06-18 2000-10-27 Dec Res Intra-vaginal delivery unit or composition containing a cyclodextrin which improves absorbtion of 17-beta oestradiol or oestradiol benzoate
GB9920167D0 (en) * 1999-08-25 1999-10-27 Avery Dennison Corp Pressure sensitive adhesive compositions
WO2001034213A1 (en) * 1999-11-09 2001-05-17 The Procter & Gamble Company Cyclodextrin compositions for odor, insect and dust mite contol
US6835717B2 (en) * 2000-03-08 2004-12-28 The Johns Hopkins University School Of Medicine β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases
KR100388605B1 (ko) * 2000-06-13 2003-06-25 코오롱제약주식회사 용해도 및 용해속도가 향상된 이트라코나졸의 액상 조성물 및 이를 이용한 이트라코나졸 제제와 그 제조방법
US20020013331A1 (en) * 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
US7544348B2 (en) 2001-02-15 2009-06-09 Access Pharmaceuticals, Inc. Liquid formulations for the prevention and treatment of mucosal diseases and disorders
EP1997478B1 (de) 2001-02-15 2013-09-04 Access Pharmaceuticals, Inc. Flüssige Formulierungen zur Vorbeugung und Behandlung von Schleimhauterkrankungen und -funktionsstörungen
PT2060259E (pt) * 2001-11-01 2010-04-26 Spectrum Pharmaceuticals Inc Composições médicas para o tratamento intravesical do cancro da bexiga
US8563592B2 (en) 2001-11-01 2013-10-22 Spectrum Pharmaceuticals, Inc. Bladder cancer treatment and methods
CN100384865C (zh) * 2001-11-02 2008-04-30 嵌入治疗公司 用于rna干扰的治疗用途的方法及组合物
US20030144362A1 (en) * 2002-01-28 2003-07-31 Utterberg David S. High viscosity antibacterials for cannulae
US20050042240A1 (en) * 2002-01-28 2005-02-24 Utterberg David S. High viscosity antibacterials
US6899890B2 (en) * 2002-03-20 2005-05-31 Kv Pharmaceutical Company Bioadhesive drug delivery system
US6824763B2 (en) 2002-05-30 2004-11-30 Kimberly-Clark Worldwide, Inc. Anti-fungal powder having enhanced excipient properties
US7977532B2 (en) 2002-09-05 2011-07-12 The Procter & Gamble Company Tampon with clean appearance post use
EP1667619A4 (de) * 2003-09-19 2007-10-10 Drugtech Corp Pharmazeutisches zufuhrsystem
US20060140990A1 (en) * 2003-09-19 2006-06-29 Drugtech Corporation Composition for topical treatment of mixed vaginal infections
US20060024372A1 (en) * 2004-07-29 2006-02-02 Utterberg David S High viscosity antibacterials
US9028852B2 (en) * 2004-09-07 2015-05-12 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
US20060275230A1 (en) 2004-12-10 2006-12-07 Frank Kochinke Compositions and methods for treating conditions of the nail unit
CA2590136A1 (en) 2004-12-10 2006-06-15 Talima Therapeutics, Inc. Compositions and methods for treating conditions of the nail unit
CA2605341A1 (en) * 2005-05-09 2006-11-16 Drugtech Corporation Modified-release pharmaceutical compositions
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
JP2009522362A (ja) * 2006-01-05 2009-06-11 ドラッグテック コーポレイション 薬物送達システム
AU2006332518A1 (en) * 2006-01-05 2007-07-12 Drugtech Corporation Composition and method of use thereof
US20090123551A1 (en) * 2007-11-13 2009-05-14 Meritage Pharma, Inc. Gastrointestinal delivery systems
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US8865692B2 (en) * 2007-11-13 2014-10-21 Meritage Pharma, Inc Compositions for the treatment of gastrointestinal inflammation
EP3574914B1 (de) 2007-11-13 2021-12-29 ViroPharma Biologics LLC Kortikosteroidzusammensetzungen
US11969501B2 (en) 2008-04-21 2024-04-30 Dompé Farmaceutici S.P.A. Auris formulations for treating otic diseases and conditions
KR20190026056A (ko) 2008-04-21 2019-03-12 오토노미, 인코포레이티드 귀 질환 및 병태를 치료하기 위한 귀 조제물
US20090264392A1 (en) * 2008-04-21 2009-10-22 Meritage Pharma, Inc. Treating eosinophilic esophagitis
CA2731769C (en) 2008-07-21 2013-09-10 Otonomy, Inc. Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders
US8784870B2 (en) * 2008-07-21 2014-07-22 Otonomy, Inc. Controlled release compositions for modulating free-radical induced damage and methods of use thereof
WO2010021636A1 (en) 2008-08-20 2010-02-25 The Regents Of The University Of California Corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
JP2016514024A (ja) 2013-03-14 2016-05-19 ハラックス,インコーポレイテッド 爪部の感染症、疾患または障害の治療方法
EP3328898B8 (de) 2015-07-28 2024-04-10 6452728 Canada Corp. Trkb- oder trkc-agonisten-zusammensetzungen und verfahren zur behandlung von erkrankungen des ohrs
KR20190024983A (ko) 2016-06-29 2019-03-08 오토노미, 인코포레이티드 트리글리세라이드 귀 제제 및 이의 용도
WO2019154895A1 (en) 2018-02-08 2019-08-15 Strekin Ag Gel formulation for preventing or treating hearing loss

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GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
DE68906942T3 (de) * 1988-03-29 1999-05-12 Univ Florida Pharmazeutische Zusammensetzungen für die parenterale Anwendung.
US5055303A (en) * 1989-01-31 1991-10-08 Kv Pharmaceutical Company Solid controlled release bioadherent emulsions
IT1250421B (it) * 1991-05-30 1995-04-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato con proprieta' bio-adesive.
ATE138561T1 (de) * 1992-02-12 1996-06-15 Janssen Cilag S P A Liposomale itraconazol formulierungen
US5324718A (en) * 1992-07-14 1994-06-28 Thorsteinn Loftsson Cyclodextrin/drug complexation
FR2719999B1 (fr) * 1994-05-17 1996-08-02 Georges Serge Grimberg Composition pharmaceutique à base de gomme de guar et d'un antiacide neutralisant, à laquelle peut être ajoutée une série de principes actifs thérapeutiques.

Also Published As

Publication number Publication date
BG100955A (en) 1998-04-30
NZ285761A (en) 1997-05-26
US5814330A (en) 1998-09-29
CZ336996A3 (en) 1997-02-12
IL113742A0 (en) 1995-08-31
ZA954023B (en) 1996-11-18
MY113846A (en) 2002-06-29
AU2526495A (en) 1995-12-05
IL113742A (en) 1999-09-22
JPH10500121A (ja) 1998-01-06
BR9507873A (pt) 1997-09-23
HU9603188D0 (en) 1997-01-28
HU218082B (hu) 2000-05-28
PL179619B1 (pl) 2000-10-31
HUT76326A (en) 1997-08-28
PL317257A1 (en) 1997-04-01
SK282623B6 (sk) 2002-10-08
ATE174790T1 (de) 1999-01-15
JP3862748B2 (ja) 2006-12-27
OA10321A (en) 1997-10-07
WO1995031178A1 (en) 1995-11-23
EE03304B1 (et) 2000-12-15
ES2127529T3 (es) 1999-04-16
RO117145B1 (ro) 2001-11-30
AU680767B2 (en) 1997-08-07
CN1091590C (zh) 2002-10-02
NO964853D0 (no) 1996-11-15
NO964853L (no) 1996-11-15
FI964589A0 (fi) 1996-11-15
NO309507B1 (no) 2001-02-12
HK1010688A1 (en) 1999-06-25
CN1148335A (zh) 1997-04-23
KR100369703B1 (ko) 2003-04-16
AP9600873A0 (en) 1996-10-31
SK146996A3 (en) 1997-05-07
FI964589A (fi) 1996-11-15
DE69506857D1 (de) 1999-02-04
EP0759741B1 (de) 1998-12-23
TW438601B (en) 2001-06-07
KR970702719A (ko) 1997-06-10
BG62754B1 (bg) 2000-07-31
AP731A (en) 1999-02-08
DK0759741T3 (da) 1999-08-23
RU2164418C2 (ru) 2001-03-27
EP0759741A1 (de) 1997-03-05
CZ285606B6 (cs) 1999-09-15

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Legal Events

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8364 No opposition during term of opposition