DE69432409T2 - Verwendung der NDV zur Herstellung eines Medikaments zur Krebsbehandlung - Google Patents

Verwendung der NDV zur Herstellung eines Medikaments zur Krebsbehandlung

Info

Publication number
DE69432409T2
DE69432409T2 DE69432409T DE69432409T DE69432409T2 DE 69432409 T2 DE69432409 T2 DE 69432409T2 DE 69432409 T DE69432409 T DE 69432409T DE 69432409 T DE69432409 T DE 69432409T DE 69432409 T2 DE69432409 T2 DE 69432409T2
Authority
DE
Germany
Prior art keywords
ndv
drug
manufacture
cancer treatment
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69432409T
Other languages
English (en)
Other versions
DE69432409D1 (de
Inventor
Robert M Lorence
Kirk W Reichard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellstat Biologics Corp
Original Assignee
Wellstat Biologics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellstat Biologics Corp filed Critical Wellstat Biologics Corp
Application granted granted Critical
Publication of DE69432409D1 publication Critical patent/DE69432409D1/de
Publication of DE69432409T2 publication Critical patent/DE69432409T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0331—Animal model for proliferative diseases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
DE69432409T 1993-04-30 1994-04-29 Verwendung der NDV zur Herstellung eines Medikaments zur Krebsbehandlung Expired - Lifetime DE69432409T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5551993A 1993-04-30 1993-04-30
PCT/US1994/004732 WO1994025627A1 (en) 1993-04-30 1994-04-29 Methods of treating and detecting cancer using viruses

Publications (2)

Publication Number Publication Date
DE69432409D1 DE69432409D1 (de) 2003-05-08
DE69432409T2 true DE69432409T2 (de) 2003-12-24

Family

ID=21998395

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69435155T Expired - Lifetime DE69435155D1 (de) 1993-04-30 1994-04-29 Zusuammensetzungen zur Behandlung von Krebs mittels Viren
DE69432409T Expired - Lifetime DE69432409T2 (de) 1993-04-30 1994-04-29 Verwendung der NDV zur Herstellung eines Medikaments zur Krebsbehandlung
DE69435118T Expired - Lifetime DE69435118D1 (de) 1993-04-30 1994-04-29 Gereinigte Zusammensetzungen von Newcastle-Krankheitvirus

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69435155T Expired - Lifetime DE69435155D1 (de) 1993-04-30 1994-04-29 Zusuammensetzungen zur Behandlung von Krebs mittels Viren

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69435118T Expired - Lifetime DE69435118D1 (de) 1993-04-30 1994-04-29 Gereinigte Zusammensetzungen von Newcastle-Krankheitvirus

Country Status (12)

Country Link
US (2) US7056689B1 (de)
EP (4) EP0696326B1 (de)
JP (3) JP4338781B2 (de)
AT (3) ATE401092T1 (de)
AU (1) AU699487B2 (de)
CA (1) CA2161671A1 (de)
DE (3) DE69435155D1 (de)
DK (3) DK0696326T5 (de)
ES (3) ES2196026T3 (de)
HK (1) HK1052871A1 (de)
PT (3) PT1314431E (de)
WO (1) WO1994025627A1 (de)

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ES2668018T3 (es) 2005-12-02 2018-05-16 Icahn School Of Medicine At Mount Sinai Virus quiméricos de la enfermedad de Newcastle que presentan proteínas de superficie no naturales y sus usos
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US9241998B2 (en) * 2007-05-21 2016-01-26 Board Of Regents, The University Of Texas System Methods and compositions for treatment of cancer using oncolytic RSV activity
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ES2550179T3 (es) 2009-02-05 2015-11-05 Icahn School Of Medicine At Mount Sinai Virus quiméricos de la enfermedad de Newcastle y usos de los mismos
ATE539148T1 (de) 2009-11-30 2012-01-15 United Cancer Res Inst Neuer klon des geflügelpestvirus, herstellung und anwendung bei der medizinischen behandlung von krebs
KR102222157B1 (ko) 2013-03-14 2021-03-03 이칸 스쿨 오브 메디슨 엣 마운트 시나이 뉴캐슬병 바이러스 및 이의 용도
CN107073099B (zh) 2014-02-27 2022-09-27 默沙东公司 用于治疗癌症的联合方法
MX2018015599A (es) 2017-05-10 2019-05-16 Wellstat Immunotherapeutics Llc Virus envuelto resistente a la inactivacion del complemento para el tratamiento del cancer.

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Also Published As

Publication number Publication date
US7056689B1 (en) 2006-06-06
DE69435118D1 (de) 2008-08-28
AU6821394A (en) 1994-11-21
ES2196026T3 (es) 2003-12-16
ES2315595T3 (es) 2009-04-01
PT1486211E (pt) 2009-02-02
DE69432409D1 (de) 2003-05-08
PT1314431E (pt) 2008-10-24
EP1314431B1 (de) 2008-07-16
ATE411809T1 (de) 2008-11-15
DK0696326T5 (da) 2003-07-14
DK1314431T3 (da) 2008-11-10
EP0696326A1 (de) 1996-02-14
EP1486211B1 (de) 2008-10-22
DK0696326T3 (da) 2003-06-23
ATE236271T1 (de) 2003-04-15
EP2009119A1 (de) 2008-12-31
JP2009149689A (ja) 2009-07-09
HK1052871A1 (zh) 2003-10-03
EP1486211A1 (de) 2004-12-15
DE69435155D1 (de) 2008-12-04
ES2310580T3 (es) 2009-01-16
EP0696326B1 (de) 2003-04-02
EP0696326A4 (de) 1997-08-20
US7736640B2 (en) 2010-06-15
US20060216310A1 (en) 2006-09-28
JP2005187484A (ja) 2005-07-14
JP4338781B2 (ja) 2009-10-07
PT696326E (pt) 2003-08-29
JPH09503995A (ja) 1997-04-22
ATE401092T1 (de) 2008-08-15
EP1314431A3 (de) 2003-06-18
WO1994025627A1 (en) 1994-11-10
CA2161671A1 (en) 1994-11-10
DK1486211T3 (da) 2009-01-19
AU699487B2 (en) 1998-12-03
EP1314431A2 (de) 2003-05-28

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