DE69326017T2 - Antibiotische zubereitung und die verwendung gegen bakterielle infektionen - Google Patents

Antibiotische zubereitung und die verwendung gegen bakterielle infektionen

Info

Publication number
DE69326017T2
DE69326017T2 DE69326017T DE69326017T DE69326017T2 DE 69326017 T2 DE69326017 T2 DE 69326017T2 DE 69326017 T DE69326017 T DE 69326017T DE 69326017 T DE69326017 T DE 69326017T DE 69326017 T2 DE69326017 T2 DE 69326017T2
Authority
DE
Germany
Prior art keywords
bacterial infection
formulation
use against
against bacterial
antibiotic preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69326017T
Other languages
English (en)
Other versions
DE69326017D1 (de
Inventor
Evan M Hersh
Eskild A Petersen
Richard T Proffitt
Kevin R Bracken
Su-Ming Chiang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nexstar Pharmaceuticals Inc
Original Assignee
Nexstar Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexstar Pharmaceuticals Inc filed Critical Nexstar Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69326017D1 publication Critical patent/DE69326017D1/de
Publication of DE69326017T2 publication Critical patent/DE69326017T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
DE69326017T 1992-12-02 1993-05-11 Antibiotische zubereitung und die verwendung gegen bakterielle infektionen Expired - Lifetime DE69326017T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1992/010591 WO1994012155A1 (en) 1992-12-02 1992-12-02 Antibiotic formulation and process
PCT/US1993/004501 WO1994012156A1 (en) 1992-12-02 1993-05-11 Antibiotic formulation and use for drug resistant infections

Publications (2)

Publication Number Publication Date
DE69326017D1 DE69326017D1 (de) 1999-09-16
DE69326017T2 true DE69326017T2 (de) 1999-12-23

Family

ID=22231603

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69326017T Expired - Lifetime DE69326017T2 (de) 1992-12-02 1993-05-11 Antibiotische zubereitung und die verwendung gegen bakterielle infektionen

Country Status (11)

Country Link
US (1) US5756121A (de)
EP (1) EP0671904B1 (de)
JP (2) JP4084846B2 (de)
AT (1) ATE183082T1 (de)
AU (2) AU3244393A (de)
CA (1) CA2150832C (de)
DE (1) DE69326017T2 (de)
DK (1) DK0671904T3 (de)
ES (1) ES2134846T3 (de)
GR (1) GR3031548T3 (de)
WO (2) WO1994012155A1 (de)

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US5958449A (en) * 1992-12-02 1999-09-28 Nexstar Pharmaceuticals, Inc. Antibiotic formulation and use for bacterial infections
US6146890A (en) * 1994-07-03 2000-11-14 Danon; David Method and system for cultivating macrophages
US5662929A (en) * 1994-12-23 1997-09-02 Universite De Montreal Therapeutic liposomal formulation
US6726925B1 (en) * 1998-06-18 2004-04-27 Duke University Temperature-sensitive liposomal formulation
US6613352B2 (en) 1999-04-13 2003-09-02 Universite De Montreal Low-rigidity liposomal formulation
GB0111279D0 (en) * 2001-05-10 2001-06-27 Nycomed Imaging As Radiolabelled liposomes
AU2003225689B2 (en) * 2002-03-05 2009-03-26 Transave, Inc. Methods for entrapment of bioactive agent in a liposome or lipid complex
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
PT1581236E (pt) * 2002-10-29 2013-12-24 Insmed Inc Libertação prolongada de anti-infecciosos
US7879351B2 (en) * 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
AU2003298738A1 (en) * 2002-11-26 2004-06-18 Su-Ming Chiang Liposomal formulations
EP3067046B1 (de) 2005-12-08 2020-03-25 Insmed Incorporated Antiinfektive zusammensetzungen auf lipidbasis zur behandlung von lungeninfekten
US20100196455A1 (en) 2007-05-04 2010-08-05 Transave, Inc. Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
SI2852391T1 (sl) 2012-05-21 2022-04-29 Insmed Incorporated Sistemi za obravnavo pljučnih infekcij
EP3461338A1 (de) 2012-07-30 2019-04-03 Matinas BioPharma Nanotechnologies, Inc. Mit sojaphosphatidylserin hergestellte cochleate
CA2891487A1 (en) 2012-11-29 2014-06-05 Insmed Incorporated Stabilized vancomycin formulations
DK3466432T3 (da) * 2014-05-15 2020-09-28 Insmed Inc Fremgangsmåder til behandling af pulmonale non-tuberkuløse mykobakterielle infektioner
WO2019156179A1 (ja) * 2018-02-07 2019-08-15 Ｊｆｅスチール株式会社 高Ｍｎ鋼およびその製造方法
WO2019191627A1 (en) 2018-03-30 2019-10-03 Insmed Incorporated Methods for continuous manufacture of liposomal drug products

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JPS5782311A (en) * 1980-11-11 1982-05-22 Tanabe Seiyaku Co Ltd Production of liposome preparation
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
US4522803A (en) * 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
FR2534487B1 (fr) * 1982-10-15 1988-06-10 Dior Christian Parfums Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede
US4981692A (en) * 1983-03-24 1991-01-01 The Liposome Company, Inc. Therapeutic treatment by intramammary infusion
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
CA1237670A (en) * 1983-05-26 1988-06-07 Andrew S. Janoff Drug preparations of reduced toxicity
CA1237671A (en) * 1983-08-01 1988-06-07 Michael W. Fountain Enhancement of pharmaceutical activity
EP0158441B2 (de) * 1984-03-08 2001-04-04 Phares Pharmaceutical Research N.V. Liposombildende Zusammensetzung
JPS6176414A (ja) * 1984-09-21 1986-04-18 Shionogi & Co Ltd リポソーム製剤の製法
US4753788A (en) * 1985-01-31 1988-06-28 Vestar Research Inc. Method for preparing small vesicles using microemulsification
US5409704A (en) * 1985-06-26 1995-04-25 The Liposome Company, Inc. Liposomes comprising aminoglycoside phosphates and methods of production and use
US5023087A (en) * 1986-02-10 1991-06-11 Liposome Technology, Inc. Efficient method for preparation of prolonged release liposome-based drug delivery system
US5043107A (en) * 1986-08-21 1991-08-27 Vestar Research, Inc. Preparation small unilamellar vesicles including polyene antifungal antibiotics
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DE3785198T3 (de) * 1986-12-23 1999-09-02 Liposome Co Inc Liposomes präparat und antibiotikum.
US5043166A (en) * 1987-01-09 1991-08-27 Hadasit Medical Research, Inc. Liposome/anthraquinone drug composition and method
ATE113468T1 (de) * 1987-07-29 1994-11-15 Liposome Co Inc Verfahren zur trennung von teilchen nach grösse.
US4946683A (en) * 1987-11-18 1990-08-07 Vestar, Inc. Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes
US5000887A (en) * 1988-05-17 1991-03-19 Liposome Technology, Inc. Preparation of uniform-size liposomes
BE1001869A3 (fr) * 1988-10-12 1990-04-03 Franz Legros Procede d'encapsulation liposomiale d'antibiotiques aminoglucosidiques, en particulier de la gentamycine.
US4952405A (en) * 1988-10-20 1990-08-28 Liposome Technology, Inc. Method of treating M. avium infection
US5043165A (en) * 1988-12-14 1991-08-27 Liposome Technology, Inc. Novel liposome composition for sustained release of steroidal drugs
US5270052A (en) * 1991-04-19 1993-12-14 New England Medical Center Hospitals, Inc. Methods and compositions for treatment of infection by intracellular parasites
CA2093381A1 (en) * 1992-04-07 1993-10-08 Hideyuki Sawahara Liposome formulation and process for production thereof
PT100486B (pt) * 1992-05-14 1999-07-30 Ineti Inst Nac Engenh E Tecnol Aminoglucosidos lipossomais com altas eficacia de encapsulacao e actividade terapeutica, nomeadamente a netilmicina, e processo para a sua preparcao
US5276452A (en) * 1992-06-24 1994-01-04 Raytheon Company Scan compensation for array antenna on a curved surface
JP3325665B2 (ja) * 1993-09-10 2002-09-17 三菱化学株式会社 オレフィン重合用触媒およびこれを用いたオレフィン重合体の製造方法

Also Published As

Publication number Publication date
EP0671904A1 (de) 1995-09-20
CA2150832C (en) 2000-01-11
WO1994012156A1 (en) 1994-06-09
GR3031548T3 (en) 2000-01-31
JP4084846B2 (ja) 2008-04-30
AU3244393A (en) 1994-06-22
ATE183082T1 (de) 1999-08-15
US5756121A (en) 1998-05-26
CA2150832A1 (en) 1994-06-09
DE69326017D1 (de) 1999-09-16
EP0671904B1 (de) 1999-08-11
AU668179B2 (en) 1996-04-26
AU4246393A (en) 1994-06-22
DK0671904T3 (da) 1999-12-06
JPH09506855A (ja) 1997-07-08
JP2005320341A (ja) 2005-11-17
WO1994012155A1 (en) 1994-06-09
ES2134846T3 (es) 1999-10-16

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