DE3852037T2 - Verfahren zur trennung von teilchen nach grösse. - Google Patents
Verfahren zur trennung von teilchen nach grösse.Info
- Publication number
- DE3852037T2 DE3852037T2 DE3852037T DE3852037T DE3852037T2 DE 3852037 T2 DE3852037 T2 DE 3852037T2 DE 3852037 T DE3852037 T DE 3852037T DE 3852037 T DE3852037 T DE 3852037T DE 3852037 T2 DE3852037 T2 DE 3852037T2
- Authority
- DE
- Germany
- Prior art keywords
- particles
- size
- tangential flow
- separating particles
- liposomes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03B—APPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
- G03B2227/00—Photographic printing apparatus
- G03B2227/32—Projection printing apparatus, e.g. enlarging apparatus, copying camera
- G03B2227/325—Microcapsule copiers
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7930987A | 1987-07-29 | 1987-07-29 | |
US16458088A | 1988-03-07 | 1988-03-07 | |
PCT/US1988/002598 WO1989000846A1 (en) | 1987-07-29 | 1988-07-28 | Method for size separation of particles |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3852037D1 DE3852037D1 (de) | 1994-12-08 |
DE3852037T2 true DE3852037T2 (de) | 1995-03-23 |
Family
ID=26761847
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3852037T Expired - Lifetime DE3852037T2 (de) | 1987-07-29 | 1988-07-28 | Verfahren zur trennung von teilchen nach grösse. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0394265B1 (de) |
JP (1) | JP2877160B2 (de) |
AT (1) | ATE113468T1 (de) |
DE (1) | DE3852037T2 (de) |
WO (1) | WO1989000846A1 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5049392A (en) * | 1989-01-18 | 1991-09-17 | The Liposome Company, Inc. | Osmotically dependent vesicles |
US5958449A (en) | 1992-12-02 | 1999-09-28 | Nexstar Pharmaceuticals, Inc. | Antibiotic formulation and use for bacterial infections |
AU3244393A (en) * | 1992-12-02 | 1994-06-22 | Vestar, Inc. | Antibiotic formulation and process |
US5759571A (en) * | 1993-05-11 | 1998-06-02 | Nexstar Pharmaceuticals, Inc. | Antibiotic formulation and use for drug resistant infections |
DK0707472T3 (da) | 1993-07-08 | 2001-04-17 | Liposome Co Inc | Fremgangsmåde til regulering af størrelsen af liposomer |
IL115849A0 (en) * | 1994-11-03 | 1996-01-31 | Merz & Co Gmbh & Co | Tangential filtration preparation of liposomal drugs and liposome product thereof |
EP1014946B1 (de) | 1997-09-18 | 2010-04-07 | Pacira Pharmaceuticals, Inc. | Retardierte freisetzung liposmaler anesthetischer zusammensetzungen. |
ES2384094T3 (es) | 1997-11-14 | 2012-06-29 | Pacira Pharmaceuticals, Inc. | Producción de liposomas multivesiculares |
US6165997A (en) * | 1997-11-20 | 2000-12-26 | Statens Serum Institut | Phospholipids having antimicrobial activity with or without the presence of antimicrobials |
FR2788780B1 (fr) * | 1999-01-27 | 2001-03-30 | Ap Cells Inc | Procede de preparation de vesicules membranaires |
EP1537846A1 (de) * | 2002-09-11 | 2005-06-08 | Tanabe Seiyaku Co., Ltd. | Verfahren zur herstellung von mikrokügelchen und gerät dafür |
JP2008540070A (ja) * | 2005-04-29 | 2008-11-20 | ユニバーシティー オブ ロチェスター | 超薄多孔質ナノスケール膜、その製造方法および使用 |
US9107824B2 (en) | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
US8613951B2 (en) | 2008-06-16 | 2013-12-24 | Bind Therapeutics, Inc. | Therapeutic polymeric nanoparticles with mTor inhibitors and methods of making and using same |
EP2309990B2 (de) | 2008-06-16 | 2017-03-15 | Pfizer Inc. | Mit wirkstoff beladene polymernanopartikel sowie verfahren zu ihrer herstellung und verwendung |
ES2721850T3 (es) | 2008-06-16 | 2019-08-05 | Pfizer | Nanopartículas poliméricas terapéuticas que comprenden alcaloides vinca y procedimientos de fabricación y uso de las mismas |
JP2012512175A (ja) | 2008-12-15 | 2012-05-31 | バインド バイオサイエンシズ インコーポレイテッド | 治療薬を徐放するための長時間循環性ナノ粒子 |
GB0917003D0 (en) * | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Purification of bacterial vesicles |
US8357401B2 (en) | 2009-12-11 | 2013-01-22 | Bind Biosciences, Inc. | Stable formulations for lyophilizing therapeutic particles |
ES2780156T3 (es) | 2009-12-15 | 2020-08-24 | Pfizer | Composiciones terapéuticas de nanopartículas poliméricas con alta temperatura de transición vítrea o copolímeros de alto peso molecular |
EP2402075A1 (de) | 2010-06-28 | 2012-01-04 | Bühler AG | Verfahren und Vorrichtung zur Herstellung von Vesikeln |
DK2892524T3 (da) | 2012-09-04 | 2021-01-25 | Eleison Pharmaceuticals LLC | Forebyggelse af pulmonalt kræfttilbagefald med lipid-komplekseret cisplatin |
BR112015005940A2 (pt) | 2012-09-17 | 2017-07-04 | Bind Therapeutics Inc | processo para a preparação de nanopartículas terapêuticas |
MX2016012009A (es) | 2014-03-14 | 2016-12-05 | Pfizer | Nanoparticulas terapeuticas que comprenden un agente terapeutico, y metodos para su elaboracion y uso. |
ES2820226T3 (es) | 2014-05-15 | 2021-04-20 | Insmed Inc | Métodos para tratar infecciones pulmonares micobacterianas no tuberculosas |
CN114146063A (zh) * | 2014-07-02 | 2022-03-08 | 川斯勒佰尔公司 | 信使rna的包封 |
JP7460534B2 (ja) * | 2018-03-30 | 2024-04-02 | インスメッド インコーポレイテッド | リポソーム医薬品の連続製造方法 |
US11357727B1 (en) | 2021-01-22 | 2022-06-14 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
US11033495B1 (en) | 2021-01-22 | 2021-06-15 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
US11278494B1 (en) | 2021-01-22 | 2022-03-22 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE8584T1 (de) * | 1980-01-16 | 1984-08-15 | Hans Georg Prof. Dr. Weder | Verfahren und dialysiereinrichtung zur herstellung von bilayer-vesikeln und verwendung der bilayer-vesikel. |
US4420398A (en) * | 1981-08-13 | 1983-12-13 | American National Red Cross | Filteration method for cell produced antiviral substances |
US4888115A (en) * | 1983-12-29 | 1989-12-19 | Cuno, Incorporated | Cross-flow filtration |
DE3432718C1 (de) * | 1984-09-06 | 1986-05-22 | Biotest Pharma GmbH, 6000 Frankfurt | Verfahren zur Herstellung einer Loesung von Milch- und/oder Kolostralimmunglobulinen |
FR2576805B1 (fr) * | 1985-02-01 | 1989-08-25 | Lyonnaise Eaux | Appareil de filtration tangentielle |
GB2176715A (en) * | 1985-06-27 | 1987-01-07 | Apv Int Ltd | Beer filtration |
IL79985A0 (en) * | 1985-09-13 | 1986-12-31 | Ausimont Spa | Purification of oils containing solid matter in suspension |
-
1988
- 1988-07-28 EP EP88906769A patent/EP0394265B1/de not_active Expired - Lifetime
- 1988-07-28 DE DE3852037T patent/DE3852037T2/de not_active Expired - Lifetime
- 1988-07-28 WO PCT/US1988/002598 patent/WO1989000846A1/en active IP Right Grant
- 1988-07-28 AT AT88906769T patent/ATE113468T1/de not_active IP Right Cessation
- 1988-07-28 JP JP63506866A patent/JP2877160B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0394265A4 (en) | 1991-07-31 |
DE3852037D1 (de) | 1994-12-08 |
JPH02504362A (ja) | 1990-12-13 |
EP0394265A1 (de) | 1990-10-31 |
EP0394265B1 (de) | 1994-11-02 |
JP2877160B2 (ja) | 1999-03-31 |
ATE113468T1 (de) | 1994-11-15 |
WO1989000846A1 (en) | 1989-02-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: ELAN PHARMACEUTICALS,INC.(N.D.GES.D.STAATES DE, US |