DE69008729T2 - Verfahren zur herstellung einer öl-in-wasser-emulsion eines wirkstoffes. - Google Patents

Verfahren zur herstellung einer öl-in-wasser-emulsion eines wirkstoffes.

Info

Publication number
DE69008729T2
DE69008729T2 DE69008729T DE69008729T DE69008729T2 DE 69008729 T2 DE69008729 T2 DE 69008729T2 DE 69008729 T DE69008729 T DE 69008729T DE 69008729 T DE69008729 T DE 69008729T DE 69008729 T2 DE69008729 T2 DE 69008729T2
Authority
DE
Germany
Prior art keywords
solution
drug
emulsion
pct
oil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69008729T
Other languages
English (en)
Other versions
DE69008729D1 (de
Inventor
Stanley Davis
Clive Washington
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Nottingham
Original Assignee
University of Nottingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Nottingham filed Critical University of Nottingham
Application granted granted Critical
Publication of DE69008729D1 publication Critical patent/DE69008729D1/de
Publication of DE69008729T2 publication Critical patent/DE69008729T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Edible Oils And Fats (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69008729T 1989-08-23 1990-08-21 Verfahren zur herstellung einer öl-in-wasser-emulsion eines wirkstoffes. Expired - Fee Related DE69008729T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898919172A GB8919172D0 (en) 1989-08-23 1989-08-23 Useful composition
PCT/GB1990/001309 WO1991002517A1 (en) 1989-08-23 1990-08-21 Process for preparation of an oil in water emulsion of a drug

Publications (2)

Publication Number Publication Date
DE69008729D1 DE69008729D1 (de) 1994-06-09
DE69008729T2 true DE69008729T2 (de) 1994-09-08

Family

ID=10662011

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69008729T Expired - Fee Related DE69008729T2 (de) 1989-08-23 1990-08-21 Verfahren zur herstellung einer öl-in-wasser-emulsion eines wirkstoffes.

Country Status (11)

Country Link
US (1) US5389373A (de)
EP (1) EP0487636B1 (de)
JP (1) JP2963538B2 (de)
AT (1) ATE105181T1 (de)
AU (1) AU629983B2 (de)
CA (1) CA2064190C (de)
DE (1) DE69008729T2 (de)
DK (1) DK0487636T3 (de)
ES (1) ES2056482T3 (de)
GB (2) GB8919172D0 (de)
WO (1) WO1991002517A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4015108A1 (de) * 1990-05-11 1991-11-14 Leopold Pharma Gmbh Stabile emulsion zur applikation pharmakologisch aktiver wirkstoffe
EP0556392A4 (de) * 1990-11-06 1994-03-17 Nippon Shinyaku Co Ltd Verfahren zur produktion einer fettemulsion.
US5534502A (en) * 1990-11-06 1996-07-09 Nippon Shinyaku Co. Ltd. Process for producing fat emulsion
GB9224502D0 (en) * 1992-11-23 1993-01-13 New Roger R C Method of preparing a lipid-containing formulation
US5785976A (en) * 1993-03-05 1998-07-28 Pharmacia & Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
US5885486A (en) 1993-03-05 1999-03-23 Pharmaciaand Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
ES2149264T3 (es) * 1993-03-22 2000-11-01 Cognis Australia Pty Ltd Agente terapeutico para el tratamiento de melanomas.
ES2178651T3 (es) * 1993-03-22 2003-01-01 Cognis Australia Pty Ltd Compuestos carotenoides terapeuticos deispersables en agua.
BR9405613A (pt) * 1993-09-29 1999-05-25 Gist Brocades Nv Uma nova composição antifúngica
SE9303281D0 (sv) * 1993-10-07 1993-10-07 Astra Ab New formulation
US5932196A (en) * 1994-11-04 1999-08-03 The Procter & Gamble Company Buffered emulsion compositions containing actives subject to acid or base hydrolysis
IL120005A (en) * 1997-01-14 2000-08-31 Ramot University Authority Of Pharmaceutical compositions for the treatment of the eye
GB9718568D0 (en) 1997-09-03 1997-11-05 Chauvin Pharmaceuticals Limite Compositions
WO1999043301A1 (en) * 1998-02-24 1999-09-02 The Board Of Trustees Of The University Of Illinois Lipid emulsions in the treatment of systemic poisoning
US6383471B1 (en) * 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
US8404217B2 (en) * 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
IN188843B (de) * 2000-06-22 2002-11-09 Vinod Daftary Gautam Dr
EP1343372A2 (de) 2000-12-21 2003-09-17 Nektar Therapeutics Pulmonale verabreichung von polyene-antipilzmitteln
US20020146385A1 (en) * 2001-04-10 2002-10-10 Lin Tung Liang Ionic antimicrobial coating
JP2008512447A (ja) * 2004-09-13 2008-04-24 ブハラット セルムズ アンド ヴァクシンズ リミテッド 防腐作用を有する静脈投与用の安定な乳剤組成物
WO2009102814A2 (en) * 2008-02-11 2009-08-20 Accentia Biopharmaceuticals, Inc. Mucosally non-irritative liquid amphotericin b formulations and methods for treating non-invasive fungus-induced mucositis
DK2879502T3 (en) 2012-07-30 2018-10-15 Matinas Biopharma Nanotechnologies Inc COCHLEATES PREPARED WITH SOYAPHOSPHATIDYLSERINE

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT70225A (en) * 1978-10-03 1979-10-01 Gist Brocades Nv Process for the preparation of sodium amoxicillin preparations
JPH0818989B2 (ja) * 1984-01-12 1996-02-28 株式会社ミドリ十字 脂肪乳剤中のプロスタグランジンの安定化方法
US4831018A (en) * 1985-05-17 1989-05-16 Smithkline Beckman Corporation Polyene antibiotic emulsion formulation
US4707470A (en) * 1985-05-17 1987-11-17 Smithkline Beckman Corporation Polyene antibiotic emulsion formulation
US4816247A (en) * 1985-09-11 1989-03-28 American Cyanamid Company Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs
US4784845A (en) * 1985-09-16 1988-11-15 American Cyanamid Company Emulsion compostions for the parenteral administration of sparingly water soluble ionizable hydrophobic drugs
DE3702029A1 (de) * 1987-01-24 1988-08-04 Basf Ag Waessriges oder pulverfoermiges, wasserdispergierbares praeparat eines in wasser schwerloeslichen pharmazeutischen wirkstoffs und verfahren zu seiner herstellung
GB8714652D0 (en) * 1987-06-23 1987-07-29 Davis S S Drug emulsion
AU598958B2 (en) * 1987-11-12 1990-07-05 Vestar, Inc. Improved amphotericin b liposome preparation

Also Published As

Publication number Publication date
GB2256136A (en) 1992-12-02
ATE105181T1 (de) 1994-05-15
JPH05500062A (ja) 1993-01-14
WO1991002517A1 (en) 1991-03-07
ES2056482T3 (es) 1994-10-01
EP0487636A1 (de) 1992-06-03
DK0487636T3 (da) 1994-06-06
CA2064190C (en) 1999-04-06
GB2256136B (en) 1993-06-02
AU629983B2 (en) 1992-10-15
DE69008729D1 (de) 1994-06-09
US5389373A (en) 1995-02-14
GB9203067D0 (en) 1992-09-23
EP0487636B1 (de) 1994-05-04
JP2963538B2 (ja) 1999-10-18
GB8919172D0 (en) 1989-10-04
AU6359190A (en) 1991-04-03
CA2064190A1 (en) 1991-02-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee