ATE135703T1 - Substituierte 2-imidazoline und verfahren zur herstellung sowie deren verwendung - Google Patents

Substituierte 2-imidazoline und verfahren zur herstellung sowie deren verwendung

Info

Publication number
ATE135703T1
ATE135703T1 AT90912283T AT90912283T ATE135703T1 AT E135703 T1 ATE135703 T1 AT E135703T1 AT 90912283 T AT90912283 T AT 90912283T AT 90912283 T AT90912283 T AT 90912283T AT E135703 T1 ATE135703 T1 AT E135703T1
Authority
AT
Austria
Prior art keywords
pct
imidazolines
substituted
production
sec
Prior art date
Application number
AT90912283T
Other languages
English (en)
Inventor
Poul Borrevang
Henrik Sune Andersen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE135703T1 publication Critical patent/ATE135703T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Lubricants (AREA)
  • Nonmetallic Welding Materials (AREA)
  • External Artificial Organs (AREA)
  • Fertilizers (AREA)
AT90912283T 1989-07-12 1990-07-12 Substituierte 2-imidazoline und verfahren zur herstellung sowie deren verwendung ATE135703T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK344489A DK344489D0 (da) 1989-07-12 1989-07-12 Substituerede 2-imidazoliner og fremstilling og anvendelse deraf

Publications (1)

Publication Number Publication Date
ATE135703T1 true ATE135703T1 (de) 1996-04-15

Family

ID=8122944

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90912283T ATE135703T1 (de) 1989-07-12 1990-07-12 Substituierte 2-imidazoline und verfahren zur herstellung sowie deren verwendung

Country Status (22)

Country Link
US (1) US5262430A (de)
EP (1) EP0482108B1 (de)
JP (1) JPH04506968A (de)
KR (1) KR927003578A (de)
CN (1) CN1049343A (de)
AT (1) ATE135703T1 (de)
AU (1) AU637393B2 (de)
CA (1) CA2064095A1 (de)
DD (1) DD296489A5 (de)
DE (1) DE69026087T2 (de)
DK (2) DK344489D0 (de)
ES (1) ES2086409T3 (de)
FI (1) FI920118A0 (de)
GR (1) GR1000716B (de)
IE (1) IE74210B1 (de)
IL (1) IL95046A (de)
NO (1) NO920143L (de)
NZ (1) NZ234451A (de)
PT (1) PT94685B (de)
WO (1) WO1991000862A1 (de)
YU (1) YU136390A (de)
ZA (1) ZA905422B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4201709A1 (de) * 1992-01-23 1993-07-29 Bayer Ag (alpha)-aryl-(alpha)-hydroxy-ss-imidazolinyl-propionsaeureamide
US5750543A (en) * 1996-02-01 1998-05-12 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US6410562B1 (en) 1998-12-18 2002-06-25 Eli Lilly And Company Hypoglycemic imidazoline compounds
US20090162342A1 (en) * 2001-06-07 2009-06-25 Sanomune Inc. Therapeutic uses of glandular kallikrein
WO2005118539A1 (en) * 2004-06-01 2005-12-15 F.Hoffmann-La Roche Ag 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitor
US20130315891A1 (en) 2012-05-25 2013-11-28 Matthew Charles Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
HUE032613T2 (en) 2012-06-04 2017-10-30 Diamedica Therapeutics Inc Human tissue kallikrein 1 is glycosylated isoforms
US11857608B2 (en) 2017-03-09 2024-01-02 Diamedica Inc. Dosage forms of tissue kallikrein 1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5936885B2 (ja) * 1976-06-24 1984-09-06 第一製薬株式会社 糖尿病治療剤
ZW13782A1 (en) * 1981-07-28 1982-10-06 Reckitt & Colmann Prod Ltd Imidazoline derivatives
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use

Also Published As

Publication number Publication date
KR927003578A (ko) 1992-12-18
EP0482108B1 (de) 1996-03-20
DD296489A5 (de) 1991-12-05
DK0482108T3 (da) 1996-07-22
CN1049343A (zh) 1991-02-20
PT94685B (pt) 1997-04-30
AU6164490A (en) 1991-02-06
IL95046A0 (en) 1991-06-10
DE69026087T2 (de) 1996-08-29
GR900100535A (en) 1991-12-10
ZA905422B (en) 1991-03-27
JPH04506968A (ja) 1992-12-03
DE69026087D1 (de) 1996-04-25
ES2086409T3 (es) 1996-07-01
GR1000716B (el) 1992-11-23
IL95046A (en) 1995-03-15
YU136390A (sh) 1993-10-20
FI920118A0 (fi) 1992-01-10
NO920143L (no) 1992-03-04
IE902546A1 (en) 1991-02-27
CA2064095A1 (en) 1991-01-13
US5262430A (en) 1993-11-16
EP0482108A1 (de) 1992-04-29
AU637393B2 (en) 1993-05-27
NZ234451A (en) 1991-08-27
DK344489D0 (da) 1989-07-12
NO920143D0 (no) 1992-01-10
IE74210B1 (en) 1997-07-16
WO1991000862A1 (en) 1991-01-24
PT94685A (pt) 1991-03-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee