ATA251584A - Verfahren zur herstellung von festen pharmazeutischen dispersionszusammensetzungen mit rascher wirkstofffreisetzung - Google Patents

Verfahren zur herstellung von festen pharmazeutischen dispersionszusammensetzungen mit rascher wirkstofffreisetzung

Info

Publication number
ATA251584A
ATA251584A AT0251584A AT251584A ATA251584A AT A251584 A ATA251584 A AT A251584A AT 0251584 A AT0251584 A AT 0251584A AT 251584 A AT251584 A AT 251584A AT A251584 A ATA251584 A AT A251584A
Authority
AT
Austria
Prior art keywords
release
rascher
solid pharmaceutical
producing solid
dispersion compositions
Prior art date
Application number
AT0251584A
Other languages
English (en)
Other versions
AT382779B (de
Inventor
Kiyoshi Okuda
Renji Aoi
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of ATA251584A publication Critical patent/ATA251584A/de
Application granted granted Critical
Publication of AT382779B publication Critical patent/AT382779B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT0251584A 1983-08-11 1984-08-03 Verfahren zur herstellung von festen pharmazeutischen dispersionszusammensetzungen mit rascher wirkstofffreisetzung AT382779B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58147871A JPS6038322A (ja) 1983-08-11 1983-08-11 ジヒドロピリジンａ物質含有易溶性固形製剤

Publications (2)

Publication Number Publication Date
ATA251584A true ATA251584A (de) 1986-09-15
AT382779B AT382779B (de) 1987-04-10

Family

ID=15440116

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0251584A AT382779B (de) 1983-08-11 1984-08-03 Verfahren zur herstellung von festen pharmazeutischen dispersionszusammensetzungen mit rascher wirkstofffreisetzung

Country Status (24)

Country Link
US (1) US4654206A (de)
EP (1) EP0137198B1 (de)
JP (1) JPS6038322A (de)
KR (1) KR910003559B1 (de)
AT (1) AT382779B (de)
AU (1) AU564506B2 (de)
BE (1) BE900348A (de)
CA (1) CA1228815A (de)
CH (1) CH660967A5 (de)
DE (1) DE3484259D1 (de)
DK (1) DK164020C (de)
ES (1) ES8601686A1 (de)
FI (1) FI83839C (de)
FR (1) FR2550444B1 (de)
GB (1) GB2145332B (de)
GR (1) GR80004B (de)
HK (1) HK6688A (de)
IE (1) IE57757B1 (de)
IL (1) IL72565A (de)
IT (1) IT1183062B (de)
MY (1) MY100042A (de)
PH (1) PH21551A (de)
SG (1) SG73087G (de)
ZA (1) ZA845844B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3424553A1 (de) * 1984-07-04 1986-01-09 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen mit dihydropyridinen und verfahren zu ihrer herstellung
GB8608080D0 (en) * 1986-04-02 1986-05-08 Fujisawa Pharmaceutical Co Solid dispersion composition
DE3887179T2 (de) * 1987-03-02 1994-06-16 Brocades Pharma Bv Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
US5045553A (en) * 1987-06-24 1991-09-03 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter
DE3720757A1 (de) * 1987-06-24 1989-01-05 Bayer Ag Dhp-manteltablette
NO883326L (no) * 1987-08-11 1989-02-13 Bayer Ag Dhp-retard-tilberedning.
PH26518A (en) * 1987-11-11 1992-08-07 Fujisawa Pharmaceutical Co A novel pharmaceutical composition comprising exifone and water-soluble polymer
JPH02206A (ja) * 1987-11-11 1990-01-05 Fujisawa Pharmaceut Co Ltd エキシホンと水溶性高分子化合物とを含有することを特徴とする新規製剤
FR2640137A1 (fr) * 1988-12-08 1990-06-15 Texinfine Sa Systemes transporteurs de principes actifs lipophiles et leur procede d'obtention
JPH0347124A (ja) * 1989-04-20 1991-02-28 Fujisawa Pharmaceut Co Ltd 経口吸収用製剤
WO1991007385A1 (en) * 1989-11-18 1991-05-30 Schering Agrochemicals Limited Preparation of propenoic acid derivatives
JP3110794B2 (ja) * 1991-06-05 2000-11-20 ユーシービージャパン株式会社 １，４−ジヒドロピリジン誘導体を含有する製剤
US5340591A (en) * 1992-01-24 1994-08-23 Fujisawa Pharmaceutical Co., Ltd. Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine
IL104192A (en) * 1992-02-17 1998-01-04 Siegfried Ag Pharma Pharmaceutical dosage forms having prolonged release rate of zero order of the active ingredient
ES2084478T3 (es) * 1992-02-17 1996-05-01 Siegfried Ag Pharma Formas de dosificacion que tienen liberacion prolongada del ingrediente activo.
DE4316537A1 (de) * 1993-05-18 1994-11-24 Basf Ag Zubereitungen in Form fester Lösungen
US5871776A (en) * 1995-01-31 1999-02-16 Mehta; Atul M. Controlled-release nifedipine
DE19511131A1 (de) * 1995-03-27 1996-10-02 Basf Ag Mechanisch stabile feste Wirkstoffzubereitungsformen
TW487582B (en) * 1995-08-11 2002-05-21 Nissan Chemical Ind Ltd Method for converting sparingly water-soluble medical substance to amorphous state
WO1997034601A1 (fr) * 1996-03-18 1997-09-25 Eisai Co., Ltd. Compositions medicamenteuses a solubilite amelioree
HN1998000115A (es) * 1997-08-21 1999-06-02 Warner Lambert Co Formas de dosificación farmacéuticas sólidas
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
JP2003146878A (ja) * 2002-11-22 2003-05-21 Sawai Pharmaceutical Co Ltd ニルバジピン含有易溶性固形製剤およびその製造法
US7732467B2 (en) * 2003-05-15 2010-06-08 Alzheimer's Institute Of America, Inc. Method for reducing amyloid deposition, amyloid neurotoxicity and microgliosis
TWI346114B (en) * 2003-09-29 2011-08-01 Method for stabilization of diarylvinylene compounds
PL1683524T3 (pl) 2003-11-14 2011-06-30 Ea Pharma Co Ltd Stała dyspersja lub preparat farmaceutyczny stałej dyspersji pochodnej fenyloalaniny
BRPI0817516A2 (pt) * 2007-10-05 2015-06-16 Alzheimer S Inst Of America Inc Método para reduzir deposição de amilóide, neurotoxicidade de amilóide e microgliose com o enantiômero de (-)-nilvadipino
US20100093810A1 (en) * 2007-10-05 2010-04-15 Alzheimer's Institute Of America, Inc. Pharmaceutical Compositions for Reducing Amyloid Deposition, Amyloid Neurotoxicity, and Microgliosis
US20150011549A1 (en) * 2012-02-15 2015-01-08 Takeda Pharmaceutical Company Limited Tablet
US9949964B2 (en) * 2016-09-07 2018-04-24 Saniona A/S Tesofensine compositions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852421A (en) * 1970-03-23 1974-12-03 Shinetsu Chemical Co Excipient and shaped medicaments prepared therewith
GB1593261A (en) * 1976-07-23 1981-07-15 Inveresk Res Int Controlled release suppository
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
CA1117117A (en) * 1978-10-10 1982-01-26 Fujisawa Pharmaceutical Co., Ltd. 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same
DE3013839A1 (de) * 1979-04-13 1980-10-30 Freunt Ind Co Ltd Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
US4259314A (en) * 1979-12-10 1981-03-31 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals
JPS5668619A (en) * 1980-10-09 1981-06-09 Yamanouchi Pharmaceut Co Ltd Nifedipine-containing solid composition
JPS5877811A (ja) * 1981-11-04 1983-05-11 Kanebo Ltd 安定な易吸収性ニフエジピン製剤の製法
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
JPS58109412A (ja) * 1981-12-23 1983-06-29 Toa Eiyou Kagaku Kogyo Kk ニフエジピン固形製剤
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
DE3307422A1 (de) * 1983-03-03 1984-09-06 Bayer Ag, 5090 Leverkusen Fluessigzubereitungen von dihydropyridinen, ein verfahren zu ihrer herstellung, sowie ihre verwendung bei der bekaempfung von erkrankungen

Also Published As

Publication number Publication date
EP0137198A2 (de) 1985-04-17
CH660967A5 (de) 1987-06-30
ZA845844B (en) 1985-05-29
IE841974L (en) 1985-02-11
ES535019A0 (es) 1985-11-01
HK6688A (en) 1988-01-29
IL72565A0 (en) 1984-11-30
GR80004B (en) 1984-11-30
ES8601686A1 (es) 1985-11-01
AU564506B2 (en) 1987-08-13
IT8422294A0 (it) 1984-08-09
KR910003559B1 (ko) 1991-06-05
DE3484259D1 (de) 1991-04-18
DK388884D0 (da) 1984-08-10
PH21551A (en) 1987-12-11
KR850001691A (ko) 1985-04-01
DK164020C (da) 1992-09-28
FR2550444B1 (fr) 1988-09-16
GB2145332B (en) 1987-03-25
EP0137198A3 (en) 1986-10-01
BE900348A (fr) 1985-02-11
MY100042A (en) 1989-06-29
AT382779B (de) 1987-04-10
IE57757B1 (en) 1993-03-24
CA1228815A (en) 1987-11-03
EP0137198B1 (de) 1991-03-13
JPS6038322A (ja) 1985-02-27
SG73087G (en) 1988-03-04
DK164020B (da) 1992-05-04
AU3130684A (en) 1985-02-14
GB8419815D0 (en) 1984-09-05
DK388884A (da) 1985-02-12
IL72565A (en) 1988-01-31
FI843083A (fi) 1985-02-12
FR2550444A1 (fr) 1985-02-15
GB2145332A (en) 1985-03-27
FI83839B (fi) 1991-05-31
FI843083A0 (fi) 1984-08-06
IT1183062B (it) 1987-10-05
JPH0412245B2 (de) 1992-03-04
FI83839C (fi) 1991-09-10
US4654206A (en) 1987-03-31

Similar Documents

Publication Publication Date Title
AT382779B (de) Verfahren zur herstellung von festen pharmazeutischen dispersionszusammensetzungen mit rascher wirkstofffreisetzung
DE3675113D1 (de) Verfahren zur herstellung von einem antithrombogenem medizinischem material.
DE68907320D1 (de) Verfahren zur herstellung von modifizierten polypropylen-zusammensetzungen.
DE3781204D1 (de) Verfahren zur herstellung von lymphokinaktivierten toetenden zellen.
DE3866906D1 (de) Verfahren zur herstellung von polyolefinen.
DE3864713D1 (de) Verfahren zur herstellung von ibuprofen.
DE3680394D1 (de) Verfahren zur herstellung von polyolefinen.
ATA337285A (de) Verfahren zur herstellung von isosilybinfreiem silibinin
DE68920814D1 (de) Verfahren zur Herstellung von Galaktooligosacchariden.
DE3785530D1 (de) Verfahren zur herstellung von l-arginin.
DE3780527D1 (de) Verfahren zur herstellung von 5'-guanyl-saeure.
DE3875280D1 (de) Verfahren zur herstellung von 9(11)-dehydro-steroidderivaten.
DE3862411D1 (de) Verfahren zur herstellung von sulfonen.
DE58905141D1 (de) Verfahren zur herstellung von cyclopropancarbonsaeureamid.
DE3884577D1 (de) Verfahren zur herstellung von polyolefinen.
DE58902242D1 (de) Verfahren zur herstellung von thymol.
DE58902114D1 (de) Verfahren zur herstellung von hydroxicarbonsaeureestern.
DE3887019D1 (de) Verfahren zur herstellung von zusammensetzungen mit anti-magengeschwür-wirkung.
DE3862210D1 (de) Verfahren zur herstellung von reinem bortrifluorid.
DE3881536D1 (de) Verfahren zur herstellung von festen polyhalotriarylphosphorsaeureestern.
DE3671216D1 (de) Verfahren zur herstellung von trifluordichlorethyl substituierten saeuren und zinkverbindungen.
DE3883394D1 (de) Verfahren zur herstellung von dialkyltellur und dialkylselen.
AT383272B (de) Verfahren zur herstellung von pharmazeutischen tabletten
DE68921984D1 (de) Verfahren zur herstellung von 4-sulfo-2-chlorbenzoesäure.
DE68907972D1 (de) Verfahren zur herstellung von l-arginin.

Legal Events

Date Code Title Description
ELA Expired due to lapse of time