DE69026087D1 - Substituierte 2-imidazoline und verfahren zur herstellung sowie deren verwendung - Google Patents

Substituierte 2-imidazoline und verfahren zur herstellung sowie deren verwendung

Info

Publication number
DE69026087D1
DE69026087D1 DE69026087T DE69026087T DE69026087D1 DE 69026087 D1 DE69026087 D1 DE 69026087D1 DE 69026087 T DE69026087 T DE 69026087T DE 69026087 T DE69026087 T DE 69026087T DE 69026087 D1 DE69026087 D1 DE 69026087D1
Authority
DE
Germany
Prior art keywords
pct
imidazolines
substituted
production
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69026087T
Other languages
English (en)
Other versions
DE69026087T2 (de
Inventor
Poul Borrevang
Henrik Andersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Application granted granted Critical
Publication of DE69026087D1 publication Critical patent/DE69026087D1/de
Publication of DE69026087T2 publication Critical patent/DE69026087T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
DE69026087T 1989-07-12 1990-07-12 Substituierte 2-imidazoline und verfahren zur herstellung sowie deren verwendung Expired - Fee Related DE69026087T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK344489A DK344489D0 (da) 1989-07-12 1989-07-12 Substituerede 2-imidazoliner og fremstilling og anvendelse deraf
PCT/DK1990/000184 WO1991000862A1 (en) 1989-07-12 1990-07-12 Substituted 2-imidazolines and preparation and use thereof

Publications (2)

Publication Number Publication Date
DE69026087D1 true DE69026087D1 (de) 1996-04-25
DE69026087T2 DE69026087T2 (de) 1996-08-29

Family

ID=8122944

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69026087T Expired - Fee Related DE69026087T2 (de) 1989-07-12 1990-07-12 Substituierte 2-imidazoline und verfahren zur herstellung sowie deren verwendung

Country Status (22)

Country Link
US (1) US5262430A (de)
EP (1) EP0482108B1 (de)
JP (1) JPH04506968A (de)
KR (1) KR927003578A (de)
CN (1) CN1049343A (de)
AT (1) ATE135703T1 (de)
AU (1) AU637393B2 (de)
CA (1) CA2064095A1 (de)
DD (1) DD296489A5 (de)
DE (1) DE69026087T2 (de)
DK (2) DK344489D0 (de)
ES (1) ES2086409T3 (de)
FI (1) FI920118A0 (de)
GR (1) GR1000716B (de)
IE (1) IE74210B1 (de)
IL (1) IL95046A (de)
NO (1) NO920143L (de)
NZ (1) NZ234451A (de)
PT (1) PT94685B (de)
WO (1) WO1991000862A1 (de)
YU (1) YU136390A (de)
ZA (1) ZA905422B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4201709A1 (de) * 1992-01-23 1993-07-29 Bayer Ag (alpha)-aryl-(alpha)-hydroxy-ss-imidazolinyl-propionsaeureamide
US5750543A (en) * 1996-02-01 1998-05-12 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US6410562B1 (en) 1998-12-18 2002-06-25 Eli Lilly And Company Hypoglycemic imidazoline compounds
US20090162342A1 (en) * 2001-06-07 2009-06-25 Sanomune Inc. Therapeutic uses of glandular kallikrein
AU2005250116B2 (en) * 2004-06-01 2011-01-20 F. Hoffmann-La Roche Ag 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitor
WO2013173923A1 (en) 2012-05-25 2013-11-28 Diamedica, Inc. Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
HUE032613T2 (en) 2012-06-04 2017-10-30 Diamedica Therapeutics Inc Human tissue kallikrein 1 is glycosylated isoforms
CA3054962A1 (en) 2017-03-09 2018-09-13 Rick PAULS Dosage forms of tissue kallikrein 1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5936885B2 (ja) * 1976-06-24 1984-09-06 第一製薬株式会社 糖尿病治療剤
NZ201219A (en) * 1981-07-28 1984-10-19 Reckitt & Colmann Prod Ltd Dihydrobenzofuranyl-2-imidazolines and pharmaceutical compositions
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use

Also Published As

Publication number Publication date
US5262430A (en) 1993-11-16
EP0482108B1 (de) 1996-03-20
AU637393B2 (en) 1993-05-27
FI920118A0 (fi) 1992-01-10
GR1000716B (el) 1992-11-23
DK0482108T3 (da) 1996-07-22
NZ234451A (en) 1991-08-27
DE69026087T2 (de) 1996-08-29
AU6164490A (en) 1991-02-06
IL95046A (en) 1995-03-15
DK344489D0 (da) 1989-07-12
DD296489A5 (de) 1991-12-05
IE74210B1 (en) 1997-07-16
ZA905422B (en) 1991-03-27
EP0482108A1 (de) 1992-04-29
YU136390A (sh) 1993-10-20
NO920143L (no) 1992-03-04
NO920143D0 (no) 1992-01-10
PT94685B (pt) 1997-04-30
ES2086409T3 (es) 1996-07-01
PT94685A (pt) 1991-03-20
ATE135703T1 (de) 1996-04-15
WO1991000862A1 (en) 1991-01-24
IE902546A1 (en) 1991-02-27
JPH04506968A (ja) 1992-12-03
CN1049343A (zh) 1991-02-20
GR900100535A (en) 1991-12-10
CA2064095A1 (en) 1991-01-13
IL95046A0 (en) 1991-06-10
KR927003578A (ko) 1992-12-18

Similar Documents

Publication Publication Date Title
ATE276757T1 (de) Zusammensetzungen aus rekonstituierten kollagenfasersegmenten und verfahren zu ihrer herstellung
DE59607490D1 (de) Verfahren zur herstellung von wirkstoffzubereitungen in form einer festen lösung des wirkstoffs in einer polymermatrix
DE69031656T2 (de) Saccharinderivate zur verwendung als proteolytische enzyminhibitoren sowie verfahren zur herstellung
DE69001573T2 (de) Zusammensetzungen zur herstellung von in dosisformen aktiven vitaminen d3 sowie verfahren zur herstellung stabiler, in dosisformen aktiver vitamine d3 unter deren verwendung.
DE69107031T2 (de) Thexyl-trialkoxysilane, Verfahren zur Herstellung und deren Verwendung.
ATE135703T1 (de) Substituierte 2-imidazoline und verfahren zur herstellung sowie deren verwendung
DE3872620D1 (de) (arylsulphonyl)-nitromethane, verfahren zu deren herstellung und deren verwendung in pharmazeutischen zusammensetzungen.
DE3770224D1 (de) Verfahren zur herstellung von hypofluoriten und bis-hypofluoriten.
DE3886936T2 (de) 2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLEN 2-PGI-DERIVATE, VERFAHREN ZUR HERSTELLUNG UND DEREN VERWENDUNG.
DE3770287D1 (de) Neue n-glycosylamidderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel.
ATE136299T1 (de) Verfahren zur herstellung der racemischen und optisch aktiven 1,2,3,4-tetrahydroisochinolin-3- carbonsäure sowie deren vorprodukte
ATE90095T1 (de) Optisch aktive produkte von 20,21dinoreburnamenin-derivaten,verfahren zur herstellung, ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammenstellungen.
AT375940B (de) Verfahren zur herstellung neuer 10-halogen-14-oxo-15-hydroxy-e-homoeburnane (3 alpha,17 alpha) sowie deren epimeren, optisch aktiven antipoden und physiologisch vertraeglichen saeureadditionssalze
ATE211460T1 (de) Verfahren zur herstellung von substituierten anthrachinonen und deren verwendung zur herstellung von rheinen
ATE37873T1 (de) Verfahren zur herstellung optisch aktiver 1,4dihydropyridine.
DE69103388T2 (de) Thexyl-(C1-C4)alkyl-dialkoxysilane, Verfahren zur Herstellung und deren Verwendung.
ATE116281T1 (de) Neue p-oxibenzoesäurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DE3863779D1 (de) Verfahren zur herstellung von stabilisierten menadionbisulfit-formulierungen.
DE59003785D1 (de) 3-substituierte 2-Hydroxy-3-formylpropionsäureester, Verfahren zu deren Herstellung sowie deren Verwendung zur Herstellung von 3-substituierten 3-Formyl-acrylsäurereestern.
ATA250986A (de) Verfahren zur herstellung neuer, optisch aktiver tert.butylester der weinsaeure und einiger o,o-diacylderivate
ATE99683T1 (de) 2,5,6,7-tetranor-4,8-inter-m-phenylen 2-pgiderivate, verfahren zur herstellung und deren verwendung.
ATA141090A (de) Verfahren zur herstellung von 3-azido-2,3didesoxy-d-erythro-pentose sowie von substituierten und unsubstituierten 3-azido-2,3- didesoxy-d-erythro-pentofuranosen und deren verwendung
DE3876448D1 (de) Verwendung eines tripeptids zur herstellung einer pharmazeutischen zusammensetzung sowie eine pharmazeutische zusammensetzung und methode.
ATA206087A (de) Verfahren zur herstellung einer octreotid enthaltenden pharmazeutischen zusammensetzung
DE3762848D1 (de) Verfahren zur herstellung von 4-(2'chlorethyl) benzoesaeure.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee