DE69515053D1 - Verfahren zur herstellung von furosemide - Google Patents
Verfahren zur herstellung von furosemideInfo
- Publication number
- DE69515053D1 DE69515053D1 DE69515053T DE69515053T DE69515053D1 DE 69515053 D1 DE69515053 D1 DE 69515053D1 DE 69515053 T DE69515053 T DE 69515053T DE 69515053 T DE69515053 T DE 69515053T DE 69515053 D1 DE69515053 D1 DE 69515053D1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- furosemide
- chloro
- producing
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
- C07C17/14—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the side-chain of aromatic compounds
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI942171A IT1271035B (it) | 1994-10-24 | 1994-10-24 | Procedimento per la preparazione della furosemide |
PCT/EP1995/004153 WO1996012714A1 (en) | 1994-10-24 | 1995-10-23 | Process for the preparation of furosemide |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69515053D1 true DE69515053D1 (de) | 2000-03-16 |
DE69515053T2 DE69515053T2 (de) | 2000-08-03 |
Family
ID=11369760
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69515053T Expired - Fee Related DE69515053T2 (de) | 1994-10-24 | 1995-10-23 | Verfahren zur herstellung von furosemide |
Country Status (8)
Country | Link |
---|---|
US (1) | US5739361A (de) |
EP (1) | EP0788494B1 (de) |
AT (1) | ATE189677T1 (de) |
AU (1) | AU3868895A (de) |
DE (1) | DE69515053T2 (de) |
ES (1) | ES2144642T3 (de) |
IT (1) | IT1271035B (de) |
WO (1) | WO1996012714A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8168674B1 (en) | 2002-02-22 | 2012-05-01 | Microdose Therapeutx, Inc. | Method for treating bronchial diseases |
CN105906589A (zh) * | 2015-10-22 | 2016-08-31 | 菏泽市方明制药有限公司 | 一种呋赛米的制备方法 |
CN106117168B (zh) * | 2016-06-30 | 2018-09-18 | 东北制药集团股份有限公司 | 一种呋塞米的制备方法 |
CN113219084A (zh) * | 2021-03-26 | 2021-08-06 | 天圣制药集团股份有限公司 | 一种呋塞米及其制剂中2-呋喃甲胺及其缩合反应杂质的hplc检测方法 |
CN117510444B (zh) * | 2024-01-06 | 2024-03-08 | 成都瑞尔医药科技有限公司 | 一种呋塞米的精制工艺 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3058882A (en) * | 1959-12-28 | 1962-10-16 | Hoechst Ag | N'-substituted-3-carboxy-6-halo-sulfanilamide and derivatives thereof |
NL126738C (de) * | 1963-04-13 | |||
DE1220436B (de) * | 1964-10-21 | 1966-07-07 | Hoechst Ag | Verfahren zur Herstellung von Sulfamylanthranilsaeuren |
DE3217619A1 (de) * | 1982-05-11 | 1983-11-17 | Bayer Ag, 5090 Leverkusen | 2,4-dihalogenbenzoyl-(thio)harnstoffe, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel |
-
1994
- 1994-10-24 IT ITMI942171A patent/IT1271035B/it active IP Right Grant
-
1995
- 1995-10-23 AT AT95937826T patent/ATE189677T1/de not_active IP Right Cessation
- 1995-10-23 US US08/817,569 patent/US5739361A/en not_active Expired - Fee Related
- 1995-10-23 AU AU38688/95A patent/AU3868895A/en not_active Abandoned
- 1995-10-23 ES ES95937826T patent/ES2144642T3/es not_active Expired - Lifetime
- 1995-10-23 DE DE69515053T patent/DE69515053T2/de not_active Expired - Fee Related
- 1995-10-23 WO PCT/EP1995/004153 patent/WO1996012714A1/en active IP Right Grant
- 1995-10-23 EP EP95937826A patent/EP0788494B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE189677T1 (de) | 2000-02-15 |
EP0788494B1 (de) | 2000-02-09 |
ES2144642T3 (es) | 2000-06-16 |
DE69515053T2 (de) | 2000-08-03 |
IT1271035B (it) | 1997-05-26 |
ITMI942171A1 (it) | 1996-04-24 |
EP0788494A1 (de) | 1997-08-13 |
AU3868895A (en) | 1996-05-15 |
ITMI942171A0 (it) | 1994-10-24 |
US5739361A (en) | 1998-04-14 |
WO1996012714A1 (en) | 1996-05-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |