DE69225542T2 - Carboxymethylmannoglukan und derivate davon - Google Patents

Carboxymethylmannoglukan und derivate davon

Info

Publication number
DE69225542T2
DE69225542T2 DE69225542T DE69225542T DE69225542T2 DE 69225542 T2 DE69225542 T2 DE 69225542T2 DE 69225542 T DE69225542 T DE 69225542T DE 69225542 T DE69225542 T DE 69225542T DE 69225542 T2 DE69225542 T2 DE 69225542T2
Authority
DE
Germany
Prior art keywords
general
formula
functional groups
carboxymethylmannoglucan
designations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69225542T
Other languages
German (de)
English (en)
Other versions
DE69225542D1 (de
Inventor
Katsutoshi Aono
Kazuhiro - - Inoue
Teruomi - - Ito
Takayuchi - - - Kawaguchi
Satoshi - - Okuno
Toshiro - - - Yano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Drug Delivery System Institute Ltd
Original Assignee
Drug Delivery System Institute Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Drug Delivery System Institute Ltd filed Critical Drug Delivery System Institute Ltd
Application granted granted Critical
Publication of DE69225542D1 publication Critical patent/DE69225542D1/de
Publication of DE69225542T2 publication Critical patent/DE69225542T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0087—Glucomannans or galactomannans; Tara or tara gum, i.e. D-mannose and D-galactose units, e.g. from Cesalpinia spinosa; Tamarind gum, i.e. D-galactose, D-glucose and D-xylose units, e.g. from Tamarindus indica; Gum Arabic, i.e. L-arabinose, L-rhamnose, D-galactose and D-glucuronic acid units, e.g. from Acacia Senegal or Acacia Seyal; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
DE69225542T 1991-02-21 1992-02-21 Carboxymethylmannoglukan und derivate davon Expired - Fee Related DE69225542T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2754491 1991-02-21
JP36039591 1991-12-27
PCT/JP1992/000184 WO1992014759A1 (fr) 1991-02-21 1992-02-21 Carboxymethylmannoglucane et derive

Publications (2)

Publication Number Publication Date
DE69225542D1 DE69225542D1 (de) 1998-06-25
DE69225542T2 true DE69225542T2 (de) 1998-09-10

Family

ID=26365480

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69225542T Expired - Fee Related DE69225542T2 (de) 1991-02-21 1992-02-21 Carboxymethylmannoglukan und derivate davon

Country Status (9)

Country Link
US (3) US5567690A (https=)
EP (1) EP0526649B1 (https=)
JP (1) JPH0784481B2 (https=)
AT (1) ATE166361T1 (https=)
CA (1) CA2081025A1 (https=)
DE (1) DE69225542T2 (https=)
DK (1) DK0526649T3 (https=)
ES (1) ES2117664T3 (https=)
WO (1) WO1992014759A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465188B1 (en) 1990-06-11 2002-10-15 Gilead Sciences, Inc. Nucleic acid ligand complexes
JPH0784481B2 (ja) * 1991-02-21 1995-09-13 株式会社デイ・デイ・エス研究所 カルボキシメチルマンノグルカン及びその誘導体
ES2149867T3 (es) * 1993-02-26 2000-11-16 Drug Delivery System Inst Ltd Derivados de polisacaridos y soportes para farmacos.
US8071737B2 (en) * 1995-05-04 2011-12-06 Glead Sciences, Inc. Nucleic acid ligand complexes
DE19524515A1 (de) * 1995-07-05 1997-01-09 Deutsches Krebsforsch Saccharid-Konjugate
TW527183B (en) 1996-06-06 2003-04-11 Daiichi Seiyaku Co Drug complex
TW409058B (en) 1996-06-06 2000-10-21 Daiichi Seiyaku Co Method for preparation of a drug complex
US6387853B1 (en) 1998-03-27 2002-05-14 Bj Services Company Derivatization of polymers and well treatments using the same
EA003398B1 (ru) 1998-05-22 2003-04-24 Дайити Фармасьютикал Ко., Лтд. Лекарственный комплекс c полимерным носителем
CN1191093C (zh) 1998-10-30 2005-03-02 第一制药株式会社 Dds化合物及其测定方法
CN1133654C (zh) * 1999-08-05 2004-01-07 武汉大学 灵芝α-(1→3)-D-葡聚糖羧甲基化衍生物及其用途和制备方法
CN100457766C (zh) * 2006-09-26 2009-02-04 重庆邮电大学 非天然活性葡聚四糖烷基苷类化合物及其制备方法和应用
CN115746153A (zh) * 2022-11-09 2023-03-07 华东理工大学 环甘露聚糖及其制备方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1053718B (it) * 1973-04-04 1981-10-10 Zambeletti Spa L Metodo per prolungare l azione di farmaci attraverso la formazione di composti mcromolecolari
JPS5366442A (en) * 1976-11-18 1978-06-13 Takuma Sasaki Antitumors
JPS5385000A (en) * 1976-12-31 1978-07-26 Akira Misaki Glucan and its preparation
JPS6045163B2 (ja) * 1977-07-01 1985-10-08 協和醗酵工業株式会社 新規組成物
JPS5461112A (en) * 1977-10-24 1979-05-17 Ono Pharmaceut Co Ltd Oncostatic polysaccharide* its preparation* and oncostatic drugs containing it as an effective component
DE3071815D1 (en) * 1980-08-05 1986-12-11 Debat Lab Use of glycosylglucanes in the treatment of infections of the large intestines
US4454289A (en) * 1981-03-06 1984-06-12 Takara Shuzo Co., Ltd. Polysaccharides having anticarcinogenic activity and method for producing same
JPS59124901A (ja) * 1982-12-29 1984-07-19 Dai Ichi Seiyaku Co Ltd 多糖誘導体
JPS61152634A (ja) * 1984-12-27 1986-07-11 Sugiyama Sangyo Kagaku Kenkyusho 固定化生理活性物質の製造法
IL73972A0 (en) * 1984-12-31 1985-03-31 Yeda Res & Dev Agents based on platinum compounds
WO1988000231A1 (fr) * 1986-06-27 1988-01-14 Kawasaki Jukogyo Kabushiki Kaisha Dispersant pour boues composees de matieres solides carbonees et d'eau et composition de boues a base de matieres solides carbonees et d'eau contenant ledit dispersant
DE3624307C1 (de) * 1986-07-18 1987-11-12 Agfa Gevaert Ag Vorrichtung zum Aufnehmen und Absetzen von Spulen
GB8713662D0 (en) * 1987-06-11 1987-07-15 Skandigen Ab Hyaluronic acid derivatives
JPS63310827A (ja) * 1987-06-15 1988-12-19 Sanwa Kagaku Kenkyusho Co Ltd ニコチン酸誘導体を主剤とする徐放性製剤
JPH0659409B2 (ja) * 1987-10-06 1994-08-10 義明 本里 架橋グルコマンナンイオン交換体
IT1224421B (it) * 1987-12-29 1990-10-04 Lamberti Flli Spa Galattomannani modificati e realtivo procedimento di preparazione
JPH01190636A (ja) * 1988-01-22 1989-07-31 Green Cross Corp:The 制癌作用物質複合体
US5124363A (en) * 1988-06-08 1992-06-23 Minnesota Mining And Manufacturing Company Aqueous air foams of polyhydroxy polymer
US5026735A (en) * 1988-06-08 1991-06-25 Minnesota Mining And Manufacturing Company Treatment of hazardous materials with aqueous air foam of polyhydroxy polymer
ATE96668T1 (de) * 1989-02-22 1993-11-15 Sanwa Kagaku Kenkyusho Co Pharmazeutische zusammensetzung, die ein hydantoin-derivat enthaelt.
JP2726520B2 (ja) * 1989-10-20 1998-03-11 名糖産業株式会社 有機磁性複合体
JPH0784481B2 (ja) * 1991-02-21 1995-09-13 株式会社デイ・デイ・エス研究所 カルボキシメチルマンノグルカン及びその誘導体
JPH0539521A (ja) * 1991-08-02 1993-02-19 Nippon Steel Corp 含クロム溶鋼の脱炭精錬法

Also Published As

Publication number Publication date
US5567690A (en) 1996-10-22
CA2081025A1 (en) 1992-08-22
EP0526649A1 (en) 1993-02-10
US5863908A (en) 1999-01-26
ES2117664T3 (es) 1998-08-16
US5863907A (en) 1999-01-26
EP0526649A4 (en) 1993-09-08
EP0526649B1 (en) 1998-05-20
JPH0784481B1 (https=) 1995-09-13
JPH0784481B2 (ja) 1995-09-13
WO1992014759A1 (fr) 1992-09-03
ATE166361T1 (de) 1998-06-15
DE69225542D1 (de) 1998-06-25
DK0526649T3 (da) 1998-10-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8320 Willingness to grant licences declared (paragraph 23)
8339 Ceased/non-payment of the annual fee