DE69218700T2 - Verfahren zur Herstellung von Riboflavin durch Fermentation - Google Patents

Verfahren zur Herstellung von Riboflavin durch Fermentation

Info

Publication number
DE69218700T2
DE69218700T2 DE69218700T DE69218700T DE69218700T2 DE 69218700 T2 DE69218700 T2 DE 69218700T2 DE 69218700 T DE69218700 T DE 69218700T DE 69218700 T DE69218700 T DE 69218700T DE 69218700 T2 DE69218700 T2 DE 69218700T2
Authority
DE
Germany
Prior art keywords
riboflavin
bacillus subtilis
medium
producing
mutant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69218700T
Other languages
German (de)
English (en)
Other versions
DE69218700D1 (de
Inventor
Tuyoshi Nakamatu
Naoki Usui
Yoko Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Application granted granted Critical
Publication of DE69218700D1 publication Critical patent/DE69218700D1/de
Publication of DE69218700T2 publication Critical patent/DE69218700T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus
    • C12R2001/125—Bacillus subtilis ; Hay bacillus; Grass bacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69218700T 1991-09-09 1992-08-04 Verfahren zur Herstellung von Riboflavin durch Fermentation Expired - Fee Related DE69218700T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3227864A JP2979767B2 (ja) 1991-09-09 1991-09-09 発酵法によるリボフラビンの製造法

Publications (2)

Publication Number Publication Date
DE69218700D1 DE69218700D1 (de) 1997-05-07
DE69218700T2 true DE69218700T2 (de) 1997-11-27

Family

ID=16867556

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69218700T Expired - Fee Related DE69218700T2 (de) 1991-09-09 1992-08-04 Verfahren zur Herstellung von Riboflavin durch Fermentation

Country Status (4)

Country Link
US (1) US5334510A (https=)
EP (1) EP0531708B1 (https=)
JP (1) JP2979767B2 (https=)
DE (1) DE69218700T2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0635572A3 (en) * 1993-06-25 1995-03-08 Hoffmann La Roche Biotin biosynthesis in Bacillus subtilis.
US7009045B2 (en) * 2000-07-14 2006-03-07 Archer-Daniels-Midland Company Transformation systems for flavinogenic yeast
US7579325B2 (en) 2001-03-21 2009-08-25 Eisai R & D Management Co., Ltd. Drugs containing reduced of vitamin B2
RU2196822C1 (ru) * 2001-07-25 2003-01-20 Институт экологии и генетики микроорганизмов Уральского отделения РАН Штамм бактерий rhodococcus erythropolis - продуцент нитрилгидратазы
RU2223316C2 (ru) * 2001-12-06 2004-02-10 ФГУП "Пермский завод им. С.М.Кирова" ШТАММ БАКТЕРИЙ rhodococcus ruber - ПРОДУЦЕНТ НИТРИЛГИДРАТАЗЫ
RU2261273C2 (ru) * 2002-11-15 2005-09-27 Федеральное Государственное Унитарное Предприятие "Государственный Научно-Исследовательский Институт Генетики И Селекции Промышленных Микроорганизмов" (Фгуп Госнии Генетика) Способ получения рибофлавина, штамм bacillus subtilis - продуцент рибофлавина (варианты)
KR100422305B1 (ko) 2002-12-05 2004-03-10 씨제이 주식회사 리보플라빈을 생산하는 미생물 및 이를 이용한리보플라빈의 생산방법
KR100422307B1 (ko) 2002-12-05 2004-03-10 씨제이 주식회사 리보플라빈을 생산하는 미생물 및 이를 이용한리보플라빈의 생산방법
KR100542563B1 (ko) * 2003-12-05 2006-01-11 씨제이 주식회사 리보플라빈을 생산하는 미생물 및 이를 이용한 리보플라빈의 생산방법
US9138963B2 (en) 2009-12-14 2015-09-22 United Technologies Corporation Low sulfur nickel base substrate alloy and overlay coating system
KR101335853B1 (ko) 2011-12-01 2013-12-02 씨제이제일제당 (주) Ｌ-아미노산 및 리보플라빈을 동시에 생산하는 미생물 및 이를 이용한 ｌ-아미노산 및 리보플라빈을 생산하는 방법
CN113317391A (zh) * 2021-06-04 2021-08-31 焦作市佰役安生物工程有限公司 改性发酵液与中药二次发酵制备饲料添加剂的方法及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5310155B2 (https=) * 1972-10-26 1978-04-11
US4165250A (en) * 1975-08-29 1979-08-21 Merck & Co., Inc. Riboflavin purification
BE890917A (fr) * 1981-10-29 1982-04-29 Vnii Genetiki Iselektsii Promy Procede microbiologique d'obtention de la riboflavine et riboflavine ainsi obtenue
CH668081A5 (de) * 1983-06-02 1988-11-30 Vnii Genetiki Selek Verfahren zur herstellung von riboflavin.

Also Published As

Publication number Publication date
EP0531708A2 (en) 1993-03-17
US5334510A (en) 1994-08-02
EP0531708B1 (en) 1997-04-02
JP2979767B2 (ja) 1999-11-15
DE69218700D1 (de) 1997-05-07
EP0531708A3 (https=) 1994-04-06
JPH0564597A (ja) 1993-03-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee