DE69122466D1 - S-(niedere fettsäuren)-substituierte glutathionderivate - Google Patents

S-(niedere fettsäuren)-substituierte glutathionderivate

Info

Publication number
DE69122466D1
DE69122466D1 DE69122466T DE69122466T DE69122466D1 DE 69122466 D1 DE69122466 D1 DE 69122466D1 DE 69122466 T DE69122466 T DE 69122466T DE 69122466 T DE69122466 T DE 69122466T DE 69122466 D1 DE69122466 D1 DE 69122466D1
Authority
DE
Germany
Prior art keywords
glutathione
substd
opt
glutathion
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69122466T
Other languages
English (en)
Other versions
DE69122466T2 (de
Inventor
Shinji Ohmori
Kazumi Ogata
Takahiro Sakaue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Publication of DE69122466D1 publication Critical patent/DE69122466D1/de
Application granted granted Critical
Publication of DE69122466T2 publication Critical patent/DE69122466T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69122466T 1990-04-26 1991-04-26 S-(niedere fettsäuren)-substituierte glutathionderivate Expired - Fee Related DE69122466T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11226090 1990-04-26
PCT/JP1991/000581 WO1991016338A1 (en) 1990-04-26 1991-04-26 S-(lower fatty acid)-substituted glutathione derivative

Publications (2)

Publication Number Publication Date
DE69122466D1 true DE69122466D1 (de) 1996-11-07
DE69122466T2 DE69122466T2 (de) 1997-03-20

Family

ID=14582257

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69123428T Expired - Fee Related DE69123428T2 (de) 1990-04-26 1991-04-25 Inhibitor von lebererkrankungen
DE69122831T Expired - Fee Related DE69122831T2 (de) 1990-04-26 1991-04-25 S-(niedere fettsäuren)-substituierte glutathionderivate
DE69122466T Expired - Fee Related DE69122466T2 (de) 1990-04-26 1991-04-26 S-(niedere fettsäuren)-substituierte glutathionderivate

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69123428T Expired - Fee Related DE69123428T2 (de) 1990-04-26 1991-04-25 Inhibitor von lebererkrankungen
DE69122831T Expired - Fee Related DE69122831T2 (de) 1990-04-26 1991-04-25 S-(niedere fettsäuren)-substituierte glutathionderivate

Country Status (10)

Country Link
US (2) US5232913A (de)
EP (3) EP0480061B1 (de)
KR (3) KR970002904B1 (de)
AT (3) ATE145919T1 (de)
CA (2) CA2060209A1 (de)
DE (3) DE69123428T2 (de)
ES (3) ES2093098T3 (de)
RU (1) RU2046798C1 (de)
TW (1) TW203060B (de)
WO (3) WO1991016337A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6030950A (en) * 1987-07-09 2000-02-29 Ohlenschlaeger; Gerhard Pharmaceutical therapeutic use of glutathione derivative
US5679643A (en) * 1987-10-13 1997-10-21 Terrapin Technologies, Inc. Glutathione analogs and paralog panels comprising glutathione mimics
US5599903A (en) * 1992-04-03 1997-02-04 Terrapin Technologies, Inc. Glutathione analogs and paralog panels comprising glutathione mimics
EP0469156B1 (de) * 1990-02-17 1996-10-23 Senju Pharmaceutical Co., Ltd. Glutathionderivat
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
US5955432A (en) * 1992-04-03 1999-09-21 Terrapin Technologies, Inc. Metabolic effects of certain glutathione analogs
CA2099346A1 (en) * 1992-07-17 1994-01-18 Shinji Ohmori Lipid metabolism improving composition
US5427425A (en) * 1994-08-05 1995-06-27 Droesch; Joaquin C. Pickup tailgate mounting assembly
ES2147162B1 (es) 1999-01-27 2001-03-16 Lacer Sa "s-nitrosotioles como agentes para el tratamiento de disfunciones circulatorias".
US6596870B2 (en) 2000-07-13 2003-07-22 Brandeis University Asymmetric synthetic methods based on phase transfer catalysis
US7172905B2 (en) * 2001-08-07 2007-02-06 The University Of Chicago Polypeptide immobilization
EP2500729A1 (de) * 2002-07-05 2012-09-19 The University of Chicago Charakterisierung von Biochips mit selbstorganisierten Monoschichten
US20100021398A1 (en) * 2008-01-18 2010-01-28 Skinner Keith K Compositions and methods for lightening skin and protecting skin from ultraviolet radiation with glutathione
JP5663752B2 (ja) * 2008-05-28 2015-02-04 公立大学法人名古屋市立大学 コロイド結晶の製造方法及びコロイド結晶
JP5267096B2 (ja) * 2008-12-12 2013-08-21 住友化学株式会社 Ｎ，Ｓ−ジ−ｔｅｒｔ−ブトキシカルボニルグルタチオン蛍光誘導体及びそれを中間体として用いるグルタチオン蛍光誘導体の製造方法
US20130209366A1 (en) * 2010-08-24 2013-08-15 Oklahoma Medical Research Foundation Glutathione-Lanthionine Compounds and Methods Related Thereto
US9676818B2 (en) 2013-01-17 2017-06-13 University Of Kansas Toll-like receptor 2-agonistic lipopeptides, and method of making the same

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60104018A (ja) * 1983-11-11 1985-06-08 Kyowa Hakko Kogyo Co Ltd Ν−メチルホルムアミド肝毒性の軽減剤
US4879370A (en) * 1983-12-02 1989-11-07 Cornell Research Foundation, Inc. Glutathione delivery system
JPS61249997A (ja) * 1985-04-22 1986-11-07 コ−ネル・リサ−チ・フアウンデ−シヨン・インコ−ポレイテツド グルタチオンアルキルエステルおよびその用途
JPS60123497A (ja) * 1983-12-02 1985-07-02 コ−ネル・リサ−チ・フアウンデ−シヨン，インコ−ポレイテツド グルタチオン伝達系
JPS60237963A (ja) * 1984-05-02 1985-11-26 Ajinomoto Co Inc こく味調味料またはこく味の増強された食品の製造法
EP0202759B1 (de) * 1985-04-19 1990-06-20 Smithkline Beecham Corporation Leukotrien-Antagonisten
JPS638337A (ja) * 1986-06-30 1988-01-14 Senjiyu Seiyaku Kk 抗血液凝固剤
DE3784905T2 (de) * 1986-07-07 1993-08-05 Teijin Ltd Gamma-l-glutamyl-l-cysteinethylester und arzneimittel, die dieses als aktives mittel enthalten.
JPS6463525A (en) * 1987-05-08 1989-03-09 Yamanouchi Pharma Co Ltd Alcoholic liver triglyceride increase-suppressing agent
DE3722647A1 (de) * 1987-07-09 1989-01-19 Gerhard Ohlenschlaeger Galenische verwendung eines tripeptids als arzneimittel
JPH02255624A (ja) * 1989-03-29 1990-10-16 Senjiyu Seiyaku Kk 血小板凝集抑制剤
US5102871A (en) * 1989-04-24 1992-04-07 Kyowa Hakko Kogyo Co., Ltd. Nutrient composition
JP2815179B2 (ja) * 1989-07-14 1998-10-27 千寿製薬株式会社 抗炎症および／または抗アレルギー剤
US5093478A (en) * 1989-07-14 1992-03-03 Cornell Research Foundation, Inc. Preparing glutathione monoesters
JP2919867B2 (ja) * 1989-09-27 1999-07-19 千寿製薬株式会社 抗腫瘍剤
JP2919870B2 (ja) * 1989-09-29 1999-07-19 千寿製薬株式会社 肝障害抑制剤
EP0469156B1 (de) * 1990-02-17 1996-10-23 Senju Pharmaceutical Co., Ltd. Glutathionderivat

Also Published As

Publication number Publication date
CA2060209A1 (en) 1991-10-27
WO1991016338A1 (en) 1991-10-31
EP0480071B1 (de) 1996-10-02
DE69123428D1 (de) 1997-01-16
RU2046798C1 (ru) 1995-10-27
KR970002905B1 (ko) 1997-03-12
ES2092565T3 (es) 1996-12-01
ES2093098T3 (es) 1996-12-16
EP0480071A4 (en) 1993-06-30
US5232913A (en) 1993-08-03
KR920701143A (ko) 1992-08-11
ES2095317T3 (es) 1997-02-16
EP0480060B1 (de) 1996-10-23
DE69122831D1 (de) 1996-11-28
DE69123428T2 (de) 1997-05-15
WO1991016065A1 (en) 1991-10-31
EP0480061A4 (en) 1993-07-21
CA2060210A1 (en) 1991-10-27
DE69122466T2 (de) 1997-03-20
DE69122831T2 (de) 1997-03-27
ATE143670T1 (de) 1996-10-15
ATE144531T1 (de) 1996-11-15
KR920701142A (ko) 1992-08-11
EP0480071A1 (de) 1992-04-15
KR970002904B1 (ko) 1997-03-12
US5274177A (en) 1993-12-28
EP0480060A4 (en) 1993-07-14
EP0480061A1 (de) 1992-04-15
KR970008108B1 (ko) 1997-05-21
KR920701141A (ko) 1992-08-11
WO1991016337A1 (en) 1991-10-31
TW203060B (de) 1993-04-01
ATE145919T1 (de) 1996-12-15
EP0480061B1 (de) 1996-12-04
EP0480060A1 (de) 1992-04-15

Similar Documents

Publication Publication Date Title
DE69122466T2 (de) S-(niedere fettsäuren)-substituierte glutathionderivate
DE69132435T2 (de) Inhibitoren retroviraler Proteasen
ES2100522T3 (es) Compuesto de piridincarboximidamida y su utilizacion.
ES8103030A1 (es) Un procedimiento para la preparacion de nuevos derivados de benzamida.
DE69119668T2 (de) Hemmungsstoff für Aldosereduktase
ES2054007T3 (es) Compuesto de quinolina.
TW288013B (de)
IT1157249B (it) Procedimento per la sintesi di eteri di n-propanol-diammina
PT91145A (pt) Processo para a sintese de amino-acidos opticamente activos
FI890798A (fi) Foerfarande foer diacylering av foereningar som innehaoller tvao aromatiska kaernor.
FI941650A0 (fi) Uudet fluorikinolin-3-karboksyylihappojohdannaiset ja niiden valmistus

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee