DE3784905T2 - Gamma-l-glutamyl-l-cysteinethylester und arzneimittel, die dieses als aktives mittel enthalten. - Google Patents

Gamma-l-glutamyl-l-cysteinethylester und arzneimittel, die dieses als aktives mittel enthalten.

Info

Publication number
DE3784905T2
DE3784905T2 DE8787904324T DE3784905T DE3784905T2 DE 3784905 T2 DE3784905 T2 DE 3784905T2 DE 8787904324 T DE8787904324 T DE 8787904324T DE 3784905 T DE3784905 T DE 3784905T DE 3784905 T2 DE3784905 T2 DE 3784905T2
Authority
DE
Germany
Prior art keywords
glutamyl
gamma
active agent
ethyl ester
products containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787904324T
Other languages
English (en)
Other versions
DE3784905D1 (de
Inventor
Shigehisa Kitahara
Akira Ohtsu
Katsuhiko Fujii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of DE3784905D1 publication Critical patent/DE3784905D1/de
Publication of DE3784905T2 publication Critical patent/DE3784905T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
DE8787904324T 1986-07-07 1987-07-07 Gamma-l-glutamyl-l-cysteinethylester und arzneimittel, die dieses als aktives mittel enthalten. Expired - Lifetime DE3784905T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP15779886 1986-07-07
JP5422987 1987-03-11
PCT/JP1987/000475 WO1988000182A1 (en) 1986-07-07 1987-07-07 gamma-L-GLUTAMYL-L-CYSTEINE ETHYL ESTER AND DRUG CONTAINING IT AS EFFECTIVE INGREDIENT

Publications (2)

Publication Number Publication Date
DE3784905D1 DE3784905D1 (de) 1993-04-22
DE3784905T2 true DE3784905T2 (de) 1993-08-05

Family

ID=26394977

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787904324T Expired - Lifetime DE3784905T2 (de) 1986-07-07 1987-07-07 Gamma-l-glutamyl-l-cysteinethylester und arzneimittel, die dieses als aktives mittel enthalten.

Country Status (5)

Country Link
US (1) US4927808A (de)
EP (1) EP0276317B1 (de)
JP (1) JPS6361302B1 (de)
DE (1) DE3784905T2 (de)
WO (1) WO1988000182A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01161903U (de) * 1988-04-28 1989-11-10
JPH01306307A (ja) * 1988-05-31 1989-12-11 Hayakawa Rubber Co Ltd タイヤ滑り止め具
US5110796A (en) * 1988-12-09 1992-05-05 Yamanouchi Pharmaceutical Co., Ltd. Prophylactic and therapeutic agents for cataracts
US5102871A (en) * 1989-04-24 1992-04-07 Kyowa Hakko Kogyo Co., Ltd. Nutrient composition
WO1991016067A1 (en) * 1990-04-23 1991-10-31 Research Corporation Technologies, Inc. Soluble and stable sources of tyrosine, cysteine and glutamine for total parenteral nutrition
US5206220A (en) * 1990-04-23 1993-04-27 Research Corporation Technologies, Inc. Soluble and stable sources of tyrosine, cysteine and glutamine for total parenteral nutrition
WO1991016337A1 (en) * 1990-04-26 1991-10-31 Senju Pharmaceutical Co., Ltd. S-(lower fatty acid)-substituted glutathione derivative
JP3091270B2 (ja) * 1990-09-28 2000-09-25 協和醗酵工業株式会社 美白化粧料
IT1249047B (it) * 1991-02-21 1995-02-11 Zambon Spa Composizione farmaceutica per il trattamento della cataratta
US5464825A (en) * 1991-03-14 1995-11-07 Cornell Research Foundation, Inc. Raising glutathione equivalent levels using N-acyl glutathione monoesters
US5631234A (en) * 1991-04-15 1997-05-20 Teijin Limited Method for treating ischemia-reperfusion tissue injury
KR0159949B1 (ko) * 1991-04-15 1998-12-01 이다가끼 히로시 허혈-재관류 조직 장해, 부정맥, 및 활성산소 및 자유 라디칼에 의해 야기된 폐장해의 예방 또는 치료제
US5977073A (en) * 1991-06-06 1999-11-02 Life Sciences' Technologies, Inc. Nutrient composition for treatment of immune disorders
WO1994025052A1 (en) * 1993-05-03 1994-11-10 Cornell Research Foundation, Inc. Use of glutathione diesters
US5624955A (en) * 1995-05-03 1997-04-29 Regents Of The University Of Minnesota Compounds that enhance the concentration of glutathione in tissues
RU2089179C1 (ru) * 1995-12-14 1997-09-10 Закрытое акционерное общество "ВАМ" Стимулятор эндогенной продукции цитокинов и гепопоэтических факторов и способ его использования
US6251857B1 (en) 1995-12-14 2001-06-26 Novelos Therapeutics, Inc. Cytokine and hemopoietic factor endogenous production enhancer and methods of use thereof
US6057367A (en) 1996-08-30 2000-05-02 Duke University Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
NZ334577A (en) * 1996-09-12 2001-03-30 Sankyo Co Glutathione reductase activity potentiator containing troglitazone
US6251868B1 (en) * 1998-04-30 2001-06-26 Teijin Limited Method for treating a human immunodeficiency virus infection
RU2144374C1 (ru) * 1998-11-23 2000-01-20 Закрытое акционерное общество "ВАМ" Способ получения композита окисленного глутатиона с cis-диаминодихлорплатиной и фармацевтических композиций на его основе, регулирующих метаболизм, пролиферацию, дифференцировку и механизмы апоптоза нормальных и трансформированных клеток
US20070142267A1 (en) * 1998-11-23 2007-06-21 Novelos Therapeutics, Inc. Methods for production of the oxidized glutathione composite with CIS-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells
FR2794122B1 (fr) * 1999-05-27 2001-09-07 Centre Nat Rech Scient Nouveaux antioxydants, procedes de preparation et utilisations
US6495170B1 (en) * 2000-08-16 2002-12-17 N. V. Nutricia Method of increasing the presence of glutathione in cells
GB0520872D0 (en) * 2005-10-14 2005-11-23 Hofmann Thomas F Onion flavour compounds and use
WO2007055388A2 (en) * 2005-11-09 2007-05-18 Ajinomoto Co., Inc. Calcium receptor activator
US8420144B2 (en) * 2005-11-09 2013-04-16 Ajinomoto Co., Inc. Kokumi-imparting agent, method of using, and compositions containing same
EP1946110B1 (de) * 2005-11-09 2010-10-06 Ajinomoto Co., Inc. Screening-verfahren für kokumi-vermittelnde agentien
EP2141995B1 (de) 2007-03-27 2014-11-05 Perscitus Biosciences, LLC Zusammensetzungen und ihre verwendungen zum schutz von zellen gegen toxische wirkungen
CA2686795C (en) * 2007-05-08 2015-11-24 Ajinomoto Co., Inc. Low-fat food comprising a calcium receptor
EP2269646A4 (de) * 2008-02-25 2011-06-29 Ajinomoto Kk Prophylaktischer oder therapeutischer wirkstoff gegen diabetes oder adipositas
US20110064828A1 (en) * 2009-09-11 2011-03-17 Novelos Therapeutics, Incorporated Treatment of metastatic tumors and other conditions
WO2014209412A1 (en) * 2013-06-29 2014-12-31 Viva Pharmaceutical, Inc. N-acetyl l-cysteine chelates and methods for making and using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA583262A (en) * 1959-09-15 Joullie Maurice Cysteine ester compositions
EP0071485B1 (de) * 1981-07-30 1989-09-20 Akira Kimura Mikroorganismen durch Mutation abgeleitet von Mikroorganismen des Genus Escherichia und ihre Verwendung in der Herstellung von Glutathion
JPS5820188A (ja) * 1981-07-30 1983-02-05 Tanabe Seiyaku Co Ltd 新規微生物及びそれを用いるグルタチオンの製造法
US4710489A (en) * 1985-04-22 1987-12-01 Cornell Research Foundation, Inc. Glutathione delivery system

Also Published As

Publication number Publication date
US4927808A (en) 1990-05-22
WO1988000182A1 (en) 1988-01-14
EP0276317A4 (de) 1989-09-19
DE3784905D1 (de) 1993-04-22
EP0276317B1 (de) 1993-03-17
EP0276317A1 (de) 1988-08-03
JPS6361302B1 (de) 1988-11-28

Similar Documents

Publication Publication Date Title
DE3784905D1 (de) Gamma-l-glutamyl-l-cysteinethylester und arzneimittel, die dieses als aktives mittel enthalten.
DE3854148D1 (de) Fluorcytidinderivate, deren Herstellung und Arzneimittel, die diese Derivate enthalten.
DE68920394D1 (de) Heterozyklische Verbindungen und Arzneimittel, die die Wirkung von Antikrebsmitteln verstärken, welche diese als wirksame Bestandteile enthalten.
NO874873D0 (no) Innretning for autoadministrering av fysiologisk aktive stoffer.
NL194239B (nl) Dialkoxyfosfinolmethylbenzamideverbindingen en farmaceutische preparaten, die deze bevatten.
NL192721B (nl) Benzonorborneenderivaten, werkwijzen voor het bereiden ervan alsmede geneeskundige en cosmetische preparaten, die dergelijke derivaten bevatten.
ATE81505T1 (de) Azacycloalkanderivate, absorptionspromotoren, die die derivate als effektiven inhaltsstoff enthalten und aeusserlich anzuwendende praeparate, die absorptionspromotoren enthalten.
DE3676148D1 (de) Antigerinnungsmittel, verfahren zu seiner herstellung und dieses mittel als wirkender grundstoff enthaltende antikoagulantia.
DE3771146D1 (de) Pyrimidinderivate, ihre herstellung und medikamente, die diese derivate enthalten.
NL8601838A (nl) Distamycinederivaten, werkwijze voor de bereiding ervan, alsmede farmaceutische preparaten, die deze derivaten bevatten.
DE3685604D1 (de) 1,7-naphthyridinderivate und diese enthaltende arzneimittel.
DE3788195T2 (de) DIBENZ[b,e]OXEPINDERIVATE, SOWIE ARZNEIMITTEL, DIE DIESE ALS AKTIVE MITTEL ENTHALTEN.
NL194612B (nl) Aromatische, alkenisch onverzadigde retino´den, alsmede dergelijke verbindingen bevattende farmaceutische en cosmetische preparaten.
DE3481125D1 (de) Pheophorbidderivate und diese enthaltende pharmazeutische mittel.
NL193946B (nl) Alkeenzuuresters van een antibioticum alsmede farmaceutische en cosmetische preparaten die dergelijke esters bevatten.
DE3686245D1 (de) Amidderivate und antiallergische mittel, die sie enthalten.
DE3575422D1 (de) Benzo-a,d,h-b,d-cinnolin-verbindungen, deren herstellung und arzneimittel die diese enthalten.
DE3874390D1 (de) Carboxystyrol-derivate und arzneimittel, die sie als wirkstoff enthalten.
DE3878774D1 (de) Paraherquamid und dihydroparaherquamid als antiparasitaere mittel.
ATE67210T1 (de) Androstane-17-beta-carbonsaeureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten.
DE69327495D1 (de) Arzneimittel die Glicentin als aktiven Wirkstoff enthalten
DE69002533T2 (de) Indan-1,3-dionderivate und herbizide Zusammensetzungen, die diese als aktiven Bestandteil enthalten.
DE69018914T2 (de) Pharmakologisch aktive Präparate und sie enthaltende Arzneimittel.
DE3678541D1 (de) N-vinylimidazole und -triazole und diese enthaltende arzneimittel.
DE69301261D1 (de) Indan-1,3-Dionderivate und Herbizide, die diese als aktiven Bestandteil enthalten