DE68924069D1 - Kollagen-wundheilmatrizen und verfahren zur herstellung. - Google Patents

Kollagen-wundheilmatrizen und verfahren zur herstellung.

Info

Publication number
DE68924069D1
DE68924069D1 DE68924069T DE68924069T DE68924069D1 DE 68924069 D1 DE68924069 D1 DE 68924069D1 DE 68924069 T DE68924069 T DE 68924069T DE 68924069 T DE68924069 T DE 68924069T DE 68924069 D1 DE68924069 D1 DE 68924069D1
Authority
DE
Germany
Prior art keywords
wound healing
manufacture
collagen
implants
healing matrices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68924069T
Other languages
English (en)
Other versions
DE68924069T2 (de
Inventor
George Chu
Yasushi Ogawa
John Mcpherson
George Ksander
Bruce Pratt
Diana Hendricks
Hugh Mcmullin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Collagen Aesthetics Inc
Original Assignee
Collagen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/213,726 external-priority patent/US5024841A/en
Application filed by Collagen Corp filed Critical Collagen Corp
Publication of DE68924069D1 publication Critical patent/DE68924069D1/de
Application granted granted Critical
Publication of DE68924069T2 publication Critical patent/DE68924069T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25—Peptides having up to 20 amino acids in a defined sequence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/426—Immunomodulating agents, i.e. cytokines, interleukins, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/08—Collagen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/924—Material characteristic

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE68924069T 1988-06-30 1989-06-28 Kollagen-wundheilmatrizen und verfahren zur herstellung. Expired - Fee Related DE68924069T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/213,726 US5024841A (en) 1988-06-30 1988-06-30 Collagen wound healing matrices and process for their production
US07/286,303 US4950483A (en) 1988-06-30 1988-12-16 Collagen wound healing matrices and process for their production
PCT/US1989/002799 WO1990000060A1 (en) 1988-06-30 1989-06-28 Collagen wound healing matrices and process for their production

Publications (2)

Publication Number Publication Date
DE68924069D1 true DE68924069D1 (de) 1995-10-05
DE68924069T2 DE68924069T2 (de) 1996-03-14

Family

ID=26908351

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68924069T Expired - Fee Related DE68924069T2 (de) 1988-06-30 1989-06-28 Kollagen-wundheilmatrizen und verfahren zur herstellung.

Country Status (8)

Country Link
US (1) US4950483A (de)
EP (1) EP0428541B1 (de)
JP (1) JP2820209B2 (de)
AT (1) ATE127022T1 (de)
AU (1) AU623163B2 (de)
CA (1) CA1339007C (de)
DE (1) DE68924069T2 (de)
WO (1) WO1990000060A1 (de)

Families Citing this family (238)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
US5219576A (en) * 1988-06-30 1993-06-15 Collagen Corporation Collagen wound healing matrices and process for their production
US5110604A (en) * 1988-06-30 1992-05-05 Collagen Corporation Processes for producing collagen matrixes and methods of using same
US5447966A (en) * 1988-07-19 1995-09-05 United States Surgical Corporation Treating bioabsorbable surgical articles by coating with glycerine, polalkyleneoxide block copolymer and gelatin
IL95500A (en) * 1989-09-11 1997-03-18 Matrix Pharma ANTI-PROLIFERATIVE COMPOSITIONS CONTAINING TGF-b PROTEIN IN A VISCOUS MATRIX AND THEIR USE
DE3936568C2 (de) * 1989-11-03 1997-06-19 Karlheinz Prof Dr Dr Schmidt Wirkstoffkomplex für die Herstellung von biologischen Teilen in Form von Organen für Lebewesen; Verfahren zum Herstellen desselben und seine Verwendung
WO1991016010A1 (en) * 1990-04-24 1991-10-31 Mark Eisenberg Composite living skin equivalents
US5645591A (en) 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
ATE222117T1 (de) * 1990-05-30 2002-08-15 Harvard College Kombination aus igf-i und tgf-beta zur knochenregenerierung
US5612211A (en) * 1990-06-08 1997-03-18 New York University Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
US5292362A (en) * 1990-07-27 1994-03-08 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5500409A (en) * 1990-10-01 1996-03-19 Thomas Jefferson University Method for inhibiting collagen synthesis by keloid fibroblasts
US5713888A (en) * 1990-10-31 1998-02-03 Baxter International, Inc. Tissue implant systems
AU645155B2 (en) * 1990-10-31 1994-01-06 Baxter International Inc. Close vascularization implant material
US5314471A (en) * 1991-07-24 1994-05-24 Baxter International Inc. Tissue inplant systems and methods for sustaining viable high cell densities within a host
US5344454A (en) * 1991-07-24 1994-09-06 Baxter International Inc. Closed porous chambers for implanting tissue in a host
US5545223A (en) * 1990-10-31 1996-08-13 Baxter International, Inc. Ported tissue implant systems and methods of using same
EP0565620B1 (de) * 1991-01-03 1995-09-20 The Salk Institute For Biological Studies Mitotoxin zur behandlung von gefässbeschädigung
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
US5853746A (en) * 1991-01-31 1998-12-29 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone using functional barrier
AU1462392A (en) * 1991-02-22 1992-09-15 Amgen, Inc. Use of gm-csf and g-csf to promote accelerated wound healing
US5192312A (en) * 1991-03-05 1993-03-09 Colorado State University Research Foundation Treated tissue for implantation and methods of treatment and use
WO1992017209A1 (en) * 1991-04-08 1992-10-15 Sumitomo Pharmaceuticals Company, Limited Porous solid preparation containing physiologically active protein substance
AU654574B2 (en) * 1991-06-14 1994-11-10 Amgen, Inc. Collagen film drug delivery for proteins
CA2071137A1 (en) * 1991-07-10 1993-01-11 Clarence C. Lee Composition and method for revitalizing scar tissue
US5453278A (en) * 1991-07-24 1995-09-26 Baxter International Inc. Laminated barriers for tissue implants
US6773458B1 (en) 1991-07-24 2004-08-10 Baxter International Inc. Angiogenic tissue implant systems and methods
US5270300A (en) * 1991-09-06 1993-12-14 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone
CA2080538A1 (en) * 1991-10-21 1993-04-22 Joseph V. Bondi Lyophilized acidic fibroblast growth factor
US6352707B1 (en) 1992-02-24 2002-03-05 Anton-Lewis Usala Transplant encapsulation in a hydrogel matrix to obscure immune recognition
US6231881B1 (en) 1992-02-24 2001-05-15 Anton-Lewis Usala Medium and matrix for long-term proliferation of cells
AU3733293A (en) * 1992-02-25 1993-09-13 Alteon Inc. Method and agents for promoting wound healing
US5480644A (en) * 1992-02-28 1996-01-02 Jsf Consultants Ltd. Use of injectable biomaterials for the repair and augmentation of the anal sphincters
GB9206509D0 (en) * 1992-03-25 1992-05-06 Jevco Ltd Heteromorphic sponges containing active agents
IL105529A0 (en) * 1992-05-01 1993-08-18 Amgen Inc Collagen-containing sponges as drug delivery for proteins
US5322933A (en) * 1992-05-07 1994-06-21 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Crystal structure of TGF-β-2
FR2693907B1 (fr) * 1992-07-23 1994-09-02 Rhone Poulenc Rorer Sa Procédé d'administration de solutions de facteur de stimulation des colonies granulocytaires.
US5800537A (en) * 1992-08-07 1998-09-01 Tissue Engineering, Inc. Method and construct for producing graft tissue from an extracellular matrix
DE69333466T2 (de) * 1992-08-07 2004-08-19 TEI Biosciences, Inc., Boston Herstellung von transplantatgeweben aus extrazellulärer matrix
US7214654B1 (en) 1994-12-07 2007-05-08 Karlheinz Schmidt Agent for the manufacture of biological parts including an active ingredient complex and carrying materials suitable for the active ingredient complex
US5928635A (en) * 1994-12-07 1999-07-27 Schmidt; Karlheinz Process for producing active agent complexes
US5830859A (en) * 1992-09-17 1998-11-03 Schmidt; Karlheinz Complex for inducing bone growth in the maxillary sinus
US5916553A (en) * 1992-09-17 1999-06-29 Schmidt; Karlheinz Complex for inducing bone growth in the mastoid cavity
US5358935A (en) * 1992-11-19 1994-10-25 Robert Allen Smith Nonantigenic keratinous protein material
CA2114290C (en) * 1993-01-27 2006-01-10 Nagabushanam Totakura Post-surgical anti-adhesion device
US5786327A (en) 1993-03-12 1998-07-28 Gensci Regeneration Sciences Inc. Bone stimulating factor, methods of isolating same, and methods of increasing bone growth comprising administering same
US5578569A (en) * 1993-03-12 1996-11-26 Tam; Cherk S. Method of increasing bone growth
US5565210A (en) * 1993-03-22 1996-10-15 Johnson & Johnson Medical, Inc. Bioabsorbable wound implant materials
CA2121192A1 (en) * 1993-04-21 1994-10-22 Kiminori Atsumi Collagen membranes
WO1994027630A1 (fr) * 1993-05-31 1994-12-08 Kaken Pharmaceutical Co., Ltd. Preparation de gel a base de gelatine reticulee contenant un facteur de croissance de fibroblaste de base
US5531791A (en) * 1993-07-23 1996-07-02 Bioscience Consultants Composition for repair of defects in osseous tissues, method of making, and prosthesis
EP0637450A3 (de) * 1993-08-04 1995-04-05 Collagen Corp Verfahren und Zusammensetzung zur Wiederbelebung von Nerbgewebe.
US5523291A (en) * 1993-09-07 1996-06-04 Datascope Investment Corp. Injectable compositions for soft tissue augmentation
GB2281861B (en) * 1993-09-21 1997-08-20 Johnson & Johnson Medical Bioabsorbable wound implant materials containing microspheres
WO1995008355A1 (en) * 1993-09-24 1995-03-30 Baxter International Inc. Methods for enhancing vascularization of implant devices
GB2282328B (en) * 1993-09-29 1997-10-08 Johnson & Johnson Medical Absorbable structures for ligament and tendon repair
US5393594A (en) * 1993-10-06 1995-02-28 United States Surgical Corporation Absorbable non-woven fabric
US5656598A (en) * 1994-03-08 1997-08-12 Rhone-Poulenc Rorer Pharmaceuticals Inc. Use of fibroblast growth factors to stimulate bone growth
JPH09510209A (ja) * 1994-03-08 1997-10-14 オステオサ インコーポレイテッド 骨の成長を刺激するための繊維芽細胞成長因子の用途
AU1931495A (en) * 1994-03-14 1995-10-03 Cryolife, Inc. Treated tissue for implantation and preparation methods
CA2484826C (en) * 1994-04-29 2007-12-18 Scimed Life Systems, Inc. Stent with collagen
US6156305A (en) * 1994-07-08 2000-12-05 Baxter International Inc. Implanted tumor cells for the prevention and treatment of cancer
AU1287895A (en) 1994-10-03 1996-04-26 Otogen Corporation Differentially biodegradable biomedical implants
US5709934A (en) * 1994-11-22 1998-01-20 Tissue Engineering, Inc. Bipolymer foams having extracellular matrix particulates
US5693341A (en) * 1995-03-16 1997-12-02 Collagen Corporation Affinity bound collagen matrices for the delivery of biologically active agents
US6337389B1 (en) 1995-03-17 2002-01-08 Bioscience Consultants, L.L.C. Method and process for the production of collagen preparations from invertebrate marine animals and compositions thereof
US6352973B1 (en) 1995-06-07 2002-03-05 Osteopharm Inc. Bone stimulating factor
US6693081B2 (en) 1995-09-26 2004-02-17 Osteopharm Inc. Bone stimulating factor
US5733884A (en) * 1995-11-07 1998-03-31 Nestec Ltd. Enteral formulation designed for optimized wound healing
US6458889B1 (en) 1995-12-18 2002-10-01 Cohesion Technologies, Inc. Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
US7883693B2 (en) 1995-12-18 2011-02-08 Angiodevice International Gmbh Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
US6833408B2 (en) * 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
WO1997022371A1 (en) * 1995-12-18 1997-06-26 Collagen Corporation Crosslinked polymer compositions and methods for their use
EP1806131A3 (de) * 1996-07-22 2007-08-01 Renovo Limited Verwendung von Sex-Steroid-Funktionsmodulatoren zur Behandlung von Wunden und fibrotischen Erkrankungen
US5827840A (en) * 1996-08-01 1998-10-27 The Research Foundation Of State University Of New York Promotion of wound healing by chemically-modified tetracyclines
CZ54899A3 (cs) 1996-08-23 1999-08-11 Cook Biotech, Incorporated Štěpová protéza, materiály s ní spojené a způsoby její výroby
US8716227B2 (en) * 1996-08-23 2014-05-06 Cook Biotech Incorporated Graft prosthesis, materials and methods
US6666892B2 (en) * 1996-08-23 2003-12-23 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
EP0941108B1 (de) * 1996-12-04 2002-10-16 Renovo Limited Wundheilung und behandlung von fibrose
US5814328A (en) 1997-01-13 1998-09-29 Gunasekaran; Subramanian Preparation of collagen using papain and a reducing agent
US6022694A (en) * 1997-04-04 2000-02-08 Regeneron Pharmaceuticals, Inc. Assay for ligands to tyrosine kinase receptors
US6017366A (en) * 1997-04-18 2000-01-25 W. L. Gore & Associates, Inc. Resorbable interposition arthroplasty implant
US6511958B1 (en) 1997-08-14 2003-01-28 Sulzer Biologics, Inc. Compositions for regeneration and repair of cartilage lesions
DE69714035T2 (de) 1997-08-14 2003-03-06 Sulzer Innotec Ag, Winterthur Zusammensetzung und Vorrichtung zur Reparatur von Knorpelgewebe in vivo bestehend aus Nanokapseln mit osteoinduktiven und/oder chondroinduktiven Faktoren
US20040081704A1 (en) * 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
US6194378B1 (en) 1998-02-18 2001-02-27 The Research Foundation Of State University Of New York Fibronectin peptides-based extracellular matrix for wound healing
AU757968B2 (en) * 1998-07-10 2003-03-13 Encelle, Inc. Methods for increasing vascularization and promoting wound healing
US6992066B2 (en) * 1998-10-16 2006-01-31 Zimmer Orthobiologics, Inc. Povidone-containing carriers for polypeptide growth factors
US7087577B2 (en) * 1998-10-16 2006-08-08 Zimmer Orthobiologies, Inc. Method of promoting natural bypass
US6110484A (en) * 1998-11-24 2000-08-29 Cohesion Technologies, Inc. Collagen-polymer matrices with differential biodegradability
US8882850B2 (en) * 1998-12-01 2014-11-11 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
CA2319447C (en) 1998-12-01 2010-01-26 Washington University Embolization device
US6328765B1 (en) 1998-12-03 2001-12-11 Gore Enterprise Holdings, Inc. Methods and articles for regenerating living tissue
US6946140B1 (en) * 1999-02-09 2005-09-20 The Research Foundation Of State University Of New York Methods and compositions for enhancing fibroblast migration
AU2875600A (en) * 1999-02-09 2000-08-29 Research Foundation Of The State University Of New York, The Methods and compositions for enhancing fibroblast migration
DE19957388A1 (de) 1999-11-24 2001-06-13 Michael Sittinger Chondroinduktive und implantierbare Substrate zur Knorpelheilung und -protektion
DE60018480T2 (de) * 2000-03-09 2006-02-16 Syntacoll Ag Mehrschicht-kollagenmatrix zur geweberekonstruktion
EP1265648B1 (de) * 2000-03-09 2008-03-12 Syntacoll AG NEUES MATERIAL AUF KollagenBASIS MIT VERBESSERTEN EIGENSCHAFTEN ZUR VERWENDUNG IN DER HUMAN- UND VETERINÄRMEDIZIN UND EIN HERSTELLUNGSVERFAHREN
US6309454B1 (en) 2000-05-12 2001-10-30 Johnson & Johnson Medical Limited Freeze-dried composite materials and processes for the production thereof
AU2001263495B2 (en) * 2000-05-31 2005-06-02 Encelle, Inc. Method of treating chronic ulcers
US7081240B1 (en) * 2000-06-28 2006-07-25 Zimmer Orthobiologics, Inc. Protein mixtures for wound healing
EP1307582B1 (de) * 2000-08-08 2008-05-28 M.G.V.S. Ltd. Nukleinsäurekonstrukte, damit transformierte vaskuläre zellen, pharmezeutische zusammensetzungen und verfahren zur induktion der angiogenese
AU2001286613A1 (en) 2000-08-21 2002-03-04 Rice University Tissue engineering scaffolds promoting matrix protein production
US20020114795A1 (en) * 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
WO2002058718A2 (en) * 2001-01-26 2002-08-01 Genetix Pharmaceuticals, Inc. Use of compositions containing pdgf-bb for promoting angiogenesis
US6815421B1 (en) 2001-03-22 2004-11-09 Osteopharm Inc. Polypeptides for use in ameliorating effects of aging in mammals
US7232802B2 (en) * 2001-12-21 2007-06-19 Zimmer Orthobiologics, Inc. Compositions and methods for promoting myocardial and peripheral angiogenesis
CA2476656C (en) 2002-02-21 2008-11-25 Encelle, Inc. Immobilized bioactive hydrogel matrices as surface coatings
US20080086792A1 (en) 2006-10-13 2008-04-17 Thomas Charles Kuracina Method and apparatus for diverting sweat, liquid, moisture or the like from an eye
IL149562A0 (en) 2002-05-09 2002-11-10 Prochon Ltd Fgf variants and methods for use thereof
US7622562B2 (en) 2002-06-26 2009-11-24 Zimmer Orthobiologics, Inc. Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
US7846141B2 (en) * 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
ATE457716T1 (de) 2002-12-30 2010-03-15 Angiotech Int Ag Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
US20040219214A1 (en) * 2002-12-30 2004-11-04 Angiotech International Ag Tissue reactive compounds and compositions and uses thereof
US7067123B2 (en) * 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
GB0325129D0 (en) 2003-10-28 2003-12-03 Smith & Nephew Apparatus in situ
GB0325126D0 (en) 2003-10-28 2003-12-03 Smith & Nephew Apparatus with heat
GB0325130D0 (en) * 2003-10-28 2003-12-03 Smith & Nephew Apparatus with scaffold
EP2338442B1 (de) 2003-12-11 2013-01-30 Isto Technologies Inc. Teilchenförmiges Knorpelsystem
US7128735B2 (en) * 2004-01-02 2006-10-31 Richard Scott Weston Reduced pressure wound treatment appliance
US20050283256A1 (en) * 2004-02-09 2005-12-22 Codman & Shurtleff, Inc. Collagen device and method of preparing the same
US8100887B2 (en) * 2004-03-09 2012-01-24 Bluesky Medical Group Incorporated Enclosure-based reduced pressure treatment system
WO2005096988A1 (en) 2004-04-01 2005-10-20 Cook Incorporated A device for retracting the walls of a body vessel with remodelable material
US7708724B2 (en) 2004-04-05 2010-05-04 Blue Sky Medical Group Incorporated Reduced pressure wound cupping treatment system
US8062272B2 (en) 2004-05-21 2011-11-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US7776028B2 (en) * 2004-04-05 2010-08-17 Bluesky Medical Group Incorporated Adjustable overlay reduced pressure wound treatment system
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
GB0409446D0 (en) 2004-04-28 2004-06-02 Smith & Nephew Apparatus
US8529548B2 (en) 2004-04-27 2013-09-10 Smith & Nephew Plc Wound treatment apparatus and method
GB0424046D0 (en) * 2004-10-29 2004-12-01 Smith & Nephew Apparatus
KR100974733B1 (ko) 2004-04-28 2010-08-06 안지오디바이스 인터내셔널 게엠베하 가교된 생합성물질을 형성하기 위한 조성물 및 시스템, 및이와 관련된 제조 및 사용 방법
US7998125B2 (en) * 2004-05-21 2011-08-16 Bluesky Medical Group Incorporated Hypobaric chamber treatment system
FR2871061B1 (fr) * 2004-06-04 2007-08-10 Coletica Sa Principe actif capable d'induire la transformation du tgbf- latent inactif en tgfb actif
US8512730B2 (en) 2004-07-12 2013-08-20 Isto Technologies, Inc. Methods of tissue repair and compositions therefor
US8303973B2 (en) 2004-09-17 2012-11-06 Angiotech Pharmaceuticals (Us), Inc. Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
US20090319045A1 (en) * 2004-10-12 2009-12-24 Truncale Katherine G Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7803168B2 (en) 2004-12-09 2010-09-28 The Foundry, Llc Aortic valve repair
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
US8480757B2 (en) 2005-08-26 2013-07-09 Zimmer, Inc. Implants and methods for repair, replacement and treatment of disease
CN102715984B (zh) 2005-09-06 2014-07-09 施乐辉股份有限公司 具有微型泵的独立伤口敷料
DE102005045671A1 (de) * 2005-09-15 2007-03-29 Ossacur Ag Verwendung eines Kollagens xenogenen Ursprungs
AU2006292224B2 (en) 2005-09-19 2013-08-01 Histogenics Corporation Cell-support matrix and a method for preparation thereof
US7429241B2 (en) * 2005-09-29 2008-09-30 Codman & Shurtleff, Inc. Dural graft and method of preparing the same
WO2007064978A2 (en) * 2005-11-30 2007-06-07 Celator Pharmaceuticalls, Inc. Localized delivery of drug combinations
US7648527B2 (en) 2006-03-01 2010-01-19 Cook Incorporated Methods of reducing retrograde flow
CA2649729A1 (en) * 2006-04-17 2007-10-25 Hepacore Ltd. Methods for bone regeneration using endothelial progenitor cell preparations
DE102006020498A1 (de) * 2006-04-20 2007-10-25 Aesculap Ag & Co. Kg Schichtförmige Wundauflage
US7779625B2 (en) 2006-05-11 2010-08-24 Kalypto Medical, Inc. Device and method for wound therapy
US8962556B2 (en) * 2006-09-28 2015-02-24 Prochon Biotech Ltd. FGF-2 variants having N-terminal deletions and increased receptor selectivity and uses thereof
US7931651B2 (en) 2006-11-17 2011-04-26 Wake Lake University Health Sciences External fixation assembly and method of use
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US8377016B2 (en) 2007-01-10 2013-02-19 Wake Forest University Health Sciences Apparatus and method for wound treatment employing periodic sub-atmospheric pressure
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
WO2008128075A1 (en) 2007-04-12 2008-10-23 Isto Technologies, Inc. Compositions and methods for tissue repair
US8591930B2 (en) * 2007-04-27 2013-11-26 Cook Biotech Incorporated Growth factor modified extracellular matrix material preparation and methods for preparation and use thereof
US8932619B2 (en) * 2007-06-27 2015-01-13 Sofradim Production Dural repair material
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
US20090068250A1 (en) * 2007-09-07 2009-03-12 Philippe Gravagna Bioresorbable and biocompatible compounds for surgical use
ES2661762T3 (es) 2007-10-10 2018-04-03 Wake Forest University Health Sciences Dispositivos para tratar el tejido de la médula espinal
US7846199B2 (en) 2007-11-19 2010-12-07 Cook Incorporated Remodelable prosthetic valve
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
US9308068B2 (en) 2007-12-03 2016-04-12 Sofradim Production Implant for parastomal hernia
DE102007063395A1 (de) 2007-12-31 2009-07-02 Ossacur Ag Transport-, Weitergabe- und/oder Wirksystem in aseptischer Darreichung
DE202008008627U1 (de) 2008-03-07 2009-07-23 Aap Biomaterials Gmbh & Co. Kg Implantat zur Wundabdeckung
AU2009201541B2 (en) * 2008-04-23 2014-12-04 Integra Lifesciences Corporation Flowable collagen material for dural closure
US9242026B2 (en) 2008-06-27 2016-01-26 Sofradim Production Biosynthetic implant for soft tissue repair
CA2730362C (en) 2008-07-18 2018-07-10 Wake Forest University Health Sciences Apparatus and method for cardiac tissue modulation by topical application of vacuum to minimize cell death and damage
EP3202429A1 (de) * 2008-08-14 2017-08-09 Kci Licensing, Inc. Gewebegerüste
US8039433B2 (en) 2008-08-19 2011-10-18 Warsaw Orthopedic, Inc. Osteogenic compositions containing a coloring agent
US9248165B2 (en) 2008-11-05 2016-02-02 Hancock-Jaffe Laboratories, Inc. Composite containing collagen and elastin as a dermal expander and tissue filler
US8663198B2 (en) 2009-04-17 2014-03-04 Kalypto Medical, Inc. Negative pressure wound therapy device
FR2949688B1 (fr) 2009-09-04 2012-08-24 Sofradim Production Tissu avec picots revetu d'une couche microporeuse bioresorbable
KR101070358B1 (ko) 2009-12-24 2011-10-05 한국생산기술연구원 의료용 부직포 및 그의 제조방법
US8951598B2 (en) 2010-05-07 2015-02-10 Empire Technology Development Llc Nanoscale collagen particles and membranes
JPWO2011142425A1 (ja) * 2010-05-12 2013-07-22 国立大学法人 香川大学 上皮層含有組織の再生材および再生評価方法
AU2011329054B2 (en) 2010-11-15 2015-05-28 Zimmer Orthobiologics, Inc. Bone void fillers
US8722854B2 (en) 2010-12-23 2014-05-13 Medskin Solutions Dr. Suwelack Ag Degradation-stabilised, biocompatible collagen matrices
FR2972626B1 (fr) 2011-03-16 2014-04-11 Sofradim Production Prothese comprenant un tricot tridimensionnel et ajoure
JP5512887B2 (ja) * 2011-05-13 2014-06-04 学校法人北里研究所 成長因子アンカーリング型骨移植材料および成長因子アンカーリング型骨移植材料製造用キット
US9058634B2 (en) 2011-05-24 2015-06-16 Kalypto Medical, Inc. Method for providing a negative pressure wound therapy pump device
BR112013030071A2 (pt) 2011-05-24 2016-09-20 Kalypto Medical Inc dispositivo com módulos de controlador e bomba para prover uma pressão negativa para terapia de ferimento
US9067003B2 (en) 2011-05-26 2015-06-30 Kalypto Medical, Inc. Method for providing negative pressure to a negative pressure wound therapy bandage
ES2874487T3 (es) 2011-05-31 2021-11-05 Lifecell Corp Matrices de tejido adiposo
FR2977789B1 (fr) 2011-07-13 2013-07-19 Sofradim Production Prothese pour hernie ombilicale
FR2977790B1 (fr) 2011-07-13 2013-07-19 Sofradim Production Prothese pour hernie ombilicale
EP2760494B1 (de) 2011-09-30 2017-04-19 Sofradim Production Umkehrbare versteifung aus leichtgewichtigen maschen
WO2013046057A1 (en) 2011-09-30 2013-04-04 Sofradim Production Multilayer implants for delivery of therapeutic agents
CN104080468A (zh) 2011-11-02 2014-10-01 哈尔西恩股份有限公司 用于创伤治疗的方法和组合物
FR2985170B1 (fr) 2011-12-29 2014-01-24 Sofradim Production Prothese pour hernie inguinale
FR2985271B1 (fr) 2011-12-29 2014-01-24 Sofradim Production Tricot a picots
CN104144715B (zh) 2012-01-12 2016-04-27 株式会社日皮 胶原蛋白结构体及胶原蛋白结构体的制造方法
US9592278B2 (en) 2012-03-08 2017-03-14 Lifecell Corporation Enzyme-activated collagen and tissue matrices
EP2838607A4 (de) 2012-04-12 2015-12-30 Univ Wake Forest Health Sciences Entwurf einer leitung für einen peripheren nervenersatz
US9381326B2 (en) 2012-06-15 2016-07-05 W. L. Gore & Associates, Inc. Vascular occlusion and drug delivery devices, systems, and methods
EP2872191B1 (de) 2012-07-13 2019-08-07 LifeCell Corporation Verfahren zur behandlung von adipösem gewebe
FR2994185B1 (fr) 2012-08-02 2015-07-31 Sofradim Production Procede de preparation d’une couche poreuse a base de chitosane
US10092653B2 (en) 2012-09-13 2018-10-09 W. L. Gore & Associates, Inc. Polytetrafluoroethylene co-polymer emulsions
FR2995788B1 (fr) 2012-09-25 2014-09-26 Sofradim Production Patch hemostatique et procede de preparation
FR2995778B1 (fr) 2012-09-25 2015-06-26 Sofradim Production Prothese de renfort de la paroi abdominale et procede de fabrication
FR2995779B1 (fr) 2012-09-25 2015-09-25 Sofradim Production Prothese comprenant un treillis et un moyen de consolidation
CA2885327A1 (en) 2012-09-26 2014-04-03 Lifecell Corporation Processed adipose tissue
CA2880380C (en) 2012-09-28 2020-09-15 Sofradim Production Packaging for a hernia repair device
CA2889559A1 (en) 2012-10-26 2014-05-01 Wake Forest University Health Sciences Novel nanofiber-based graft for heart valve replacement and methods of using the same
US10245306B2 (en) 2012-11-16 2019-04-02 Isto Technologies Ii, Llc Flexible tissue matrix and methods for joint repair
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
EP2952214B1 (de) * 2013-03-12 2019-01-02 Fujifilm Corporation Gewebereparaturmaterial
FR3006578B1 (fr) 2013-06-07 2015-05-29 Sofradim Production Prothese a base d’un textile pour voie laparoscopique
FR3006581B1 (fr) 2013-06-07 2016-07-22 Sofradim Production Prothese a base d’un textile pour voie laparoscopique
EP3000489B1 (de) 2014-09-24 2017-04-05 Sofradim Production Verfahren zur Herstellung einer Antihaft-Sperrschicht
EP3000433B1 (de) 2014-09-29 2022-09-21 Sofradim Production Vorrichtung zur Einführung einer Prothese zur Hernie-Behandlung in einen Einschnitt und flexible textile Prothese
EP3000432B1 (de) 2014-09-29 2022-05-04 Sofradim Production Textilbasierte Prothese für die Behandlung von Leistenbruch
US10179191B2 (en) 2014-10-09 2019-01-15 Isto Technologies Ii, Llc Flexible tissue matrix and methods for joint repair
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
EP3029189B1 (de) 2014-12-05 2021-08-11 Sofradim Production Prothetisches poröses Netz, sein Herstellungsverfahren und Hernienprothese
KR101664415B1 (ko) * 2015-01-12 2016-10-12 주식회사 한국비엔씨 약물을 포함하는 콜라겐 창상피복재 및 이의 제조방법
EP3059255B1 (de) 2015-02-17 2020-05-13 Sofradim Production Verfahren zur Herstellung einer Matrix auf Chitosanbasis mit faseroptischem Verstärkungselement
EP3085337B1 (de) 2015-04-24 2022-09-14 Sofradim Production Prothese zur unterstützung einer bruststruktur
EP3106185B1 (de) 2015-06-19 2018-04-25 Sofradim Production Synthetische prothese mit einem gewirk und einem nichtporösen film und verfahren zur formung davon
EP3195830B1 (de) 2016-01-25 2020-11-18 Sofradim Production Prothese zur hernienreparatur
AU2017216898A1 (en) * 2016-02-08 2018-08-09 Lifecell Corporation Biologic breast implant
AU2017292652B2 (en) 2016-07-05 2022-03-24 Lifecell Corporation Tissue matrices incorporating multiple tissue types
EP3312325B1 (de) 2016-10-21 2021-09-22 Sofradim Production Verfahren zur herstellung eines netzes mit einem daran befestigten nahtmaterial mit widerhaken und dadurch erhaltenes netz
EP3398554A1 (de) 2017-05-02 2018-11-07 Sofradim Production Prothese zur leistenbruch-reparatur
EP3697460A1 (de) 2017-10-18 2020-08-26 LifeCell Corporation Fettgewebeprodukte und verfahren zur herstellung
US11123375B2 (en) 2017-10-18 2021-09-21 Lifecell Corporation Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
US11246994B2 (en) 2017-10-19 2022-02-15 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand
CN111225690A (zh) 2017-10-19 2020-06-02 生命细胞公司 可流动无细胞组织基质产品以及产生方法
EP3653171B1 (de) 2018-11-16 2024-08-21 Sofradim Production Implantate zur weichgewebereparatur
JP2022534110A (ja) 2019-05-30 2022-07-27 ライフセル コーポレーション 生物学的乳房インプラント
CZ309204B6 (cs) * 2019-12-17 2022-05-18 Všeobecná fakultní nemocnice v Praze Kolagenní kompozit pro řízené uvolňování aktivních látek a způsob jeho přípravy
CZ2019777A3 (cs) * 2019-12-17 2021-07-21 Všeobecná fakultní nemocnice v Praze Sendvičová kolagenní pěna pro řízené uvolňování aktivních látek a způsob její přípravy
US12064330B2 (en) 2020-04-28 2024-08-20 Covidien Lp Implantable prothesis for minimally invasive hernia repair

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3742955A (en) * 1970-09-29 1973-07-03 Fmc Corp Fibrous collagen derived product having hemostatic and wound binding properties
US3810473A (en) * 1972-12-04 1974-05-14 Avicon Inc Liquid-laid, non-woven, fibrous collagen derived surgical web having hemostatic and wound sealing properties
US4390519A (en) * 1978-05-19 1983-06-28 Sawyer Philip Nicholas Bandage with hemostatic agent and methods for preparing and employing the same
US4238480A (en) * 1978-05-19 1980-12-09 Sawyer Philip Nicholas Method for preparing an improved hemostatic agent and method of employing the same
US4404970A (en) * 1978-05-19 1983-09-20 Sawyer Philip Nicholas Hemostatic article and methods for preparing and employing the same
US4279812A (en) * 1979-09-12 1981-07-21 Seton Company Process for preparing macromolecular biologically active collagen
US4412947A (en) * 1979-09-12 1983-11-01 Seton Company Collagen sponge
DE2943520C2 (de) * 1979-10-27 1982-05-19 Fa. Carl Freudenberg, 6940 Weinheim Verfahren zur Herstellung von Kollagenschwamm für medizinische oder kosmetische Zwecke
CA1156529A (en) * 1980-06-12 1983-11-08 Fred A. Serravallo Fibrous collagenous hemostatic-adhesive webs
US4415628A (en) * 1981-10-26 1983-11-15 Seton Company Moisture vapor permeable sheet materials
US4578067A (en) * 1982-04-12 1986-03-25 Alcon (Puerto Rico) Inc. Hemostatic-adhesive, collagen dressing for severed biological surfaces
US4544516A (en) * 1982-07-28 1985-10-01 Battelle Development Corporation Collagen orientation
US4515637A (en) * 1983-11-16 1985-05-07 Seton Company Collagen-thrombin compositions
JPS59160464A (ja) * 1983-12-01 1984-09-11 株式会社高研 生体表面の被覆材の製造方法
US4745098A (en) * 1984-02-24 1988-05-17 The Regents Of The University Of California Compositions and method for improving wound healing
US4501879A (en) * 1984-03-26 1985-02-26 Eastman Kodak Company Polyesteramides and containers having improved gas barrier properties formed therefrom
IL74715A0 (en) * 1984-03-27 1985-06-30 Univ New Jersey Med Biodegradable matrix and methods for producing same
CA1259914A (en) * 1984-07-06 1989-09-26 Donald G. Wallace Methods of bone repair using collagen
US4789663A (en) * 1984-07-06 1988-12-06 Collagen Corporation Methods of bone repair using collagen
US4553974A (en) * 1984-08-14 1985-11-19 Mayo Foundation Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor
US4557764A (en) * 1984-09-05 1985-12-10 Collagen Corporation Process for preparing malleable collagen and the product thereof
US4600533A (en) * 1984-12-24 1986-07-15 Collagen Corporation Collagen membranes for medical use
CA1260391A (en) * 1985-03-28 1989-09-26 Karl A. Piez Xenogeneic collagen/mineral preparations in bone repair
CA1294546C (en) * 1986-04-23 1992-01-21 John S. Sundsmo Wound healing composition containing collagen

Also Published As

Publication number Publication date
EP0428541A1 (de) 1991-05-29
EP0428541B1 (de) 1995-08-30
US4950483A (en) 1990-08-21
EP0428541A4 (en) 1992-05-06
WO1990000060A1 (en) 1990-01-11
AU623163B2 (en) 1992-05-07
JPH04500954A (ja) 1992-02-20
ATE127022T1 (de) 1995-09-15
JP2820209B2 (ja) 1998-11-05
DE68924069T2 (de) 1996-03-14
AU3964689A (en) 1990-01-23
CA1339007C (en) 1997-03-25

Similar Documents

Publication Publication Date Title
DE68924069D1 (de) Kollagen-wundheilmatrizen und verfahren zur herstellung.
Gomes et al. Histologic evaluation of the osteoinductive property of autogenous demineralized dentin matrix on surgical bone defects in rabbit skulls using human amniotic membrane for guided bone regeneration.
Um et al. Demineralized dentin matrix scaffolds for alveolar bone engineering
DE69032424T2 (de) Osteogene vorrichtungen
Babu Collagen based dressings—a review
EP0612252B1 (de) Wundabdeckungsmaterial auf basis von kollagenfasern
DE69735998D1 (de) Zusammensetzungen zur behandlung und wiederherstellung von knorpeldefekten mit funktioneller sperrschicht
US20070276398A1 (en) Methods of repairing longitudinal bone defects
KR890700033A (ko) 외상치료 및 뼈 재생
MX9206315A (es) Heterodimeros recombinantes de proteinas morfogenicas de hueso, composiciones de estos y metodos para su uso.
Wikesjö et al. Periodontal repair in dogs: Space‐providing ePTFE devices increase rhBMP‐2/ACS‐induced bone formation
ATE549996T1 (de) Verfahren zur herstellung von chitosan- wundauflagen
WO1998022155A1 (fr) Canal rachidien artificiel
JP2002531193A (ja) 生きた組織を再生するための方法および物品
ATE189401T1 (de) Implantat
KR20070004844A (ko) 뼈 형성용 기질 컴포지트, 그의 제조 방법 및 그로 코팅된조직 공학용 지지체
DE102004022645A1 (de) Bioresorbierbares Material auf Kollagen-Basis
JP2873082B2 (ja) 骨の手術に使用するための移植片
JP2002536016A5 (de)
McPherson The utility of collagen-based vehicles in delivery of growth factors for hard and soft tissue wound repair
ATE124863T1 (de) Knochenwachstumsstimulator.
Shi et al. Periodontal regeneration in experimentally-induced alveolar bone dehiscence by an improved porous biphasic calcium phosphate ceramic in beagle dogs
Zellin et al. Bone neogenesis in domes made of expanded polytetrafluoroethylene: Efficacy of rhBMP-2 to enhance the amount of achievable bone in rats
Murata et al. Bone induction in subcutaneous tissue in rats by a newly developed DNA-coated atelocollagen and bone morphogenetic protein
Côté et al. In vitro contraction rate of collagen in sponge-shape matrices

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee