DE60335543D1 - Zusammensetzung und verfahren zur herstellung von nukleinsäuren aus sputum - Google Patents

Zusammensetzung und verfahren zur herstellung von nukleinsäuren aus sputum

Info

Publication number
DE60335543D1
DE60335543D1 DE60335543T DE60335543T DE60335543D1 DE 60335543 D1 DE60335543 D1 DE 60335543D1 DE 60335543 T DE60335543 T DE 60335543T DE 60335543 T DE60335543 T DE 60335543T DE 60335543 D1 DE60335543 D1 DE 60335543D1
Authority
DE
Germany
Prior art keywords
compositions
nucleic acids
composition
sputum
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60335543T
Other languages
English (en)
Inventor
Chaim H Birnboim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DNA Genotek Inc
Original Assignee
DNA Genotek Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29740816&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60335543(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by DNA Genotek Inc filed Critical DNA Genotek Inc
Application granted granted Critical
Publication of DE60335543D1 publication Critical patent/DE60335543D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/047—Additional chamber, reservoir
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0672—Integrated piercing tool
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
DE60335543T 2002-06-07 2003-06-06 Zusammensetzung und verfahren zur herstellung von nukleinsäuren aus sputum Expired - Lifetime DE60335543D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US38639802P 2002-06-07 2002-06-07
US38639902P 2002-06-07 2002-06-07
US38639702P 2002-06-07 2002-06-07
PCT/CA2003/000869 WO2003104251A2 (en) 2002-06-07 2003-06-06 Composition and methods for obtaining nucleic acids from sputum

Publications (1)

Publication Number Publication Date
DE60335543D1 true DE60335543D1 (de) 2011-02-10

Family

ID=29740816

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60335543T Expired - Lifetime DE60335543D1 (de) 2002-06-07 2003-06-06 Zusammensetzung und verfahren zur herstellung von nukleinsäuren aus sputum

Country Status (8)

Country Link
US (7) US7482116B2 (de)
EP (1) EP1513952B1 (de)
AT (1) ATE493506T1 (de)
AU (1) AU2003240327A1 (de)
CA (1) CA2488769C (de)
DE (1) DE60335543D1 (de)
DK (1) DK1513952T3 (de)
WO (1) WO2003104251A2 (de)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
WO2004068110A2 (en) 2003-01-24 2004-08-12 University Of Utah Methods of predicting mortality risk by determining telomere length
JP4662932B2 (ja) 2003-08-15 2011-03-30 ユニバーシティー オブ サウス フロリダ 試料からの病原体の捕獲およびアウリントリカルボン酸除去のための物質および方法
AU2003300537A1 (en) * 2003-12-19 2005-07-21 Preanalytix Gmbh Composition for binding a nucleic acid to a solid phase
WO2006096973A1 (en) 2005-03-16 2006-09-21 Dna Genotek Inc. Compositions and method for storage of nucleic acid from bodily fluids
CN100478671C (zh) * 2005-10-25 2009-04-15 艾康生物技术(杭州)有限公司 用于液体样本的检测装置和方法
BRPI0619596B8 (pt) * 2005-12-09 2021-06-22 Dna Genotek Inc sistema de recipiente para o armazenamento liberável de líquido, método para combinar líquido com amostra biológica e kit para a coleta e armazenamento de amostra.
WO2007134254A2 (en) * 2006-05-12 2007-11-22 San Diego State University Research Foundation Surveying and monitoring respiratory tract viral communities using uncultured human sputum samples
EP2066686A4 (de) 2006-10-06 2010-07-14 Dna Genotek Inc Stabilisierungszusammensetzungen und verfahren zur extraktion von ribonukleinsäure
AU2013206564B2 (en) * 2006-10-06 2016-02-25 Dna Genotek Inc. Stabilizing compositions and methods for extraction of ribonucleic acid
US7521213B2 (en) * 2006-12-01 2009-04-21 Quest Diagnostics Investments Incorporated Sample processing for nucleic acid amplification
US7807359B2 (en) * 2006-12-01 2010-10-05 Quest Diagnostics Investments Incorporated Methods of detecting TPMT mutations
EP2042595A1 (de) * 2007-09-27 2009-04-01 Qiagen GmbH Permanente Deaktivierung von Nukleasen
US8813954B2 (en) * 2007-10-23 2014-08-26 Becton, Dickinson And Company Fluid displacement tissue container for molecular and histology diagnostics
CA2700914C (en) 2007-10-23 2013-05-14 Becton, Dickinson & Company Closed kit for tissue containment and stabilization for molecular and histopathology diagnostics
EP2212672B1 (de) 2007-10-23 2011-09-28 Becton, Dickinson and Company Behältersystem zur gewebestabilisierung für die molekulare und histopathologische diagnostik
CA2702790C (en) 2007-10-23 2015-06-09 Becton, Dickinson And Company Tissue container for molecular and histology diagnostics incorporating a breakable membrane
CA2716337C (en) * 2008-02-20 2017-11-14 Streck, Inc. Thermocycler and sample vessel for rapid amplification of dna
EP2326934B1 (de) * 2008-08-21 2017-04-19 DNA Genotek Inc. Probenaufnahmevorrichtung
US8039794B2 (en) * 2008-12-16 2011-10-18 Quest Diagnostics Investments Incorporated Mass spectrometry assay for thiopurine-S-methyl transferase activity and products generated thereby
JP5840950B2 (ja) 2008-12-22 2016-01-06 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション 単色マルチプレックス定量ｐｃｒ
US20100288059A1 (en) * 2009-05-14 2010-11-18 Streck, Inc. Specimen container, system, and method
EP2388312A1 (de) 2010-05-17 2011-11-23 Curetis AG Universell anwendbarer Lysepuffer und Verarbeitungsverfahren zur Lyse von Körperproben
US9737891B2 (en) 2011-06-01 2017-08-22 Streck, Inc. Rapid thermocycler system for rapid amplification of nucleic acids and related methods
CA2779850C (en) * 2011-06-17 2016-08-09 Norgen Biotek Corporation Methods, reagents and kits for preservation of nucleic acids in biological samples
MX347611B (es) 2011-06-19 2017-05-04 Abogen Inc Dispositivos, soluciones y metodos para recoleccion de muestras.
US20130164738A1 (en) * 2011-12-21 2013-06-27 Pathway Genomics Genetic Sample Collection Systems
US9040679B2 (en) 2012-04-30 2015-05-26 General Electric Company Methods and compositions for extraction and storage of nucleic acids
US9040675B2 (en) 2012-04-30 2015-05-26 General Electric Company Formulations for nucleic acid stabilization on solid substrates
US9480966B2 (en) 2012-04-30 2016-11-01 General Electric Company Substrates and methods for collection, stabilization and elution of biomolecules
US9044738B2 (en) 2012-04-30 2015-06-02 General Electric Company Methods and compositions for extraction and storage of nucleic acids
EP2883039A1 (de) 2012-08-10 2015-06-17 Streck Inc. Optisches echtzeitsystem für echtzeit-polymerasekettenreaktion
CN103196729A (zh) * 2013-04-10 2013-07-10 吴鹏 用于处理粘液的试剂
JP6546158B2 (ja) 2013-05-22 2019-07-17 テロメア ダイアグノスティクス インコーポレイテッド 短いテロメアの存在量の測定
EP3014251A1 (de) 2013-06-28 2016-05-04 Streck Inc. Vorrichtungen für echtzeit-polymerasekettenreaktionen
US9732376B2 (en) 2013-08-01 2017-08-15 Ancestry.Com Dna, Llc. Sample collection device
WO2015031994A1 (en) * 2013-09-03 2015-03-12 Dna Genotek Inc. Method and composition for nucleic acid storage from blood fractions
ES2880310T3 (es) * 2014-03-07 2021-11-24 Dna Genotek Inc Composición y método para estabilizar ácidos nucleicos en muestras biológicas
CA2947704A1 (en) 2014-04-10 2015-10-15 Dna Genotek Inc. Method and system for microbial lysis using periodates
JP2017516477A (ja) * 2014-05-27 2017-06-22 ディーエヌエー ジェノテック インク 頑丈な微生物の生存能力を安定化および維持するための組成物および方法
US9528105B2 (en) 2014-09-04 2016-12-27 Techlab, Inc. Nucleic acid extraction using organic solvents to remove inhibitors
EP3237910B1 (de) 2014-12-23 2019-04-17 Siemens Healthcare Diagnostics Inc. Proteolytischer abbau und bestimmung von herz-troponin
WO2016108954A1 (en) 2014-12-30 2016-07-07 Telomere Diagnostics, Inc. Multiplex quantitative pcr
EP3256849A4 (de) 2015-02-09 2018-12-05 Abogen, Inc. Vorrichtungen, lösungen und verfahren für anwendungen im zusammenhang mitprobeentnahme, analyse und diagnose
CN113941381A (zh) 2015-02-20 2022-01-18 文塔纳医疗系统公司 用于储存和运输浸入在流体中的组织样本的组件
ES2963004T3 (es) 2015-09-09 2024-03-22 Drawbridge Health Inc Dispositivos para la recopilación, estabilización y conservación de muestras
US10905113B2 (en) 2015-11-12 2021-02-02 Regents Of The University Of Minnesota Compositions and method for storing liquid biospecimens
US10064606B1 (en) 2015-11-25 2018-09-04 Spectrum Solutions L.L.C. Specimen collection and preservation apparatus
EP3464588B1 (de) 2016-05-27 2022-07-27 Norgen Biotek Corporation Konservierung von zellfreien nukleinsäuren in biologischen proben
US10525473B2 (en) 2016-08-03 2020-01-07 Spectrum Solutions, L.L.C. Sample collection kit including twist and tear solution cap
US10174362B2 (en) 2017-01-16 2019-01-08 Spectrum Solutions L.L.C. Nucleic acid preservation solution and methods of manufacture and use
WO2018170186A1 (en) 2017-03-15 2018-09-20 Ancestry.Com Dna, Llc Sample collection device and method
US10799422B2 (en) 2017-05-30 2020-10-13 Spectrum Solutions L.L.C. Sample collection kit including removable stopper
MX2020003624A (es) 2017-10-06 2020-09-25 Ancestry Com Dna Llc Sistemas, dispositivos y metodos para recoleccion de muestras.
CN107748095A (zh) * 2017-11-15 2018-03-02 湖南省天骑医学新技术股份有限公司 一种多用途痰标本处理装置及其方法
US11426734B2 (en) 2017-11-22 2022-08-30 Ancestry.Com Dna, Llc Sample collection kit including cap having selectively movable sleeve
MX2020005246A (es) 2017-11-22 2020-11-09 Ancestry Com Dna Llc Kit de recolección de muestras que incluye tapa con manguito que se puede mover de manera selectiva.
JP7339953B2 (ja) 2018-02-14 2023-09-06 サリグノスティクス リミテッド 分析対象物を検出するための方法及び装置
EP3826646A4 (de) * 2018-07-25 2022-07-27 Convergent Genomics, Inc. Mikrobiomische urinprofilierung
US20220003777A1 (en) * 2018-11-08 2022-01-06 The Board Of Trustees Of The Leland Stanford Junior University Methods Employing Mucin-Specific Proteases
WO2020106891A1 (en) 2018-11-20 2020-05-28 Spectrum Solutions, Llc Sample collection system including sealing cap and valve
MX2021010260A (es) 2019-02-27 2021-09-21 Ancestry Com Dna Llc Interfaz grafica de usuario que muestra el parentesco basado en el adn compartido.
US11968975B2 (en) 2019-04-30 2024-04-30 Regents Of The University Of Minnesota Compositions and methods for storing liquid biospecimens
US11701094B2 (en) 2019-06-20 2023-07-18 Spectrum Solutions L.L.C. Sample collection system including valve and plug assemblies
US20220409189A1 (en) * 2019-12-12 2022-12-29 Viome Life Sciences, Inc. Sample collection device with reagent
CN111218444B (zh) * 2020-04-24 2020-09-01 广州安必平医药科技股份有限公司 一种痰液保存液
CN113956979A (zh) * 2020-07-20 2022-01-21 袁梁 一种临床痰标本液化处理方法
GB2614481A (en) * 2020-09-01 2023-07-05 Longhorn Vaccines & Diagnostics Llc Compositions and methods for screening biological samples
WO2022195531A1 (en) * 2021-03-18 2022-09-22 Vimal Soomnath Pumposh A single time use device to identify sputum
CN113234793A (zh) * 2021-05-18 2021-08-10 江苏迅睿生物技术有限公司 一种应用于唾液病毒核酸检测的唾液样本快速处理新方法
WO2023150879A1 (en) * 2022-02-10 2023-08-17 Dna Genotek Inc. Methods and systems for defining test sample read count limits for a range of microbial sequence reads
EP4230149A1 (de) 2022-02-18 2023-08-23 MolGen B.V. Vorrichtung zum sammeln einer probe, kit mit einer solchen vorrichtung und verfahren mit einer solchen vorrichtung oder einem solchen kit

Family Cites Families (449)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2631521A (en) 1953-03-17 Beverage mixing container
US718127A (en) 1902-05-15 1903-01-13 Gus Holmgren Meat-tenderer.
US2275567A (en) 1933-11-03 1942-03-10 Arthur E Smith Container closure
US2653611A (en) 1950-11-24 1953-09-29 Arthur E Smith Closure
US2773591A (en) 1952-10-22 1956-12-11 Novo Terapeutisk Labor As Vessel with sterile closure for separate storage of at least two substances
US2764983A (en) 1953-03-20 1956-10-02 Barasch Hans Pius Dual compartment mixing vial
GB725784A (en) 1953-04-01 1955-03-09 James Garrick Sutherland Irons Improved dispensing device
US2793776A (en) 1956-05-23 1957-05-28 Lipari Michael Container attachment for providing a compartmental dispensing receptacle
US2958439A (en) 1959-04-29 1960-11-01 Donald E Yochem Container and closure
US3464414A (en) 1963-07-31 1969-09-02 Upjohn Co Mixing vial construction
US3199704A (en) 1963-10-22 1965-08-10 Guild Molders Closure and sealing assembly for bottles
US3321097A (en) 1966-05-13 1967-05-23 Solowey Ida Bottle with two or more separate compartments
US3340873A (en) 1966-05-13 1967-09-12 Solowey Ida Compartmented medical container having a rupturable diaphragm between compartments
US3347410A (en) 1966-08-31 1967-10-17 Schwartzman Gilbert Mixing assemblies for applicators
US3518164A (en) 1967-04-11 1970-06-30 B D Lab Inc Diagnostic sputum collection system
US3441179A (en) 1967-05-29 1969-04-29 Ways & Means Inc Mixing container
US3419179A (en) 1967-06-07 1968-12-31 Brunswick Corp Captive cap specimen vial
GB1235668A (en) 1967-08-03 1971-06-16 Amalgamated Dental Co Ltd Containers for two-part mixtures
US3537606A (en) 1968-06-17 1970-11-03 Ida Solowey Compartment bottle
US3603484A (en) 1969-02-28 1971-09-07 Mix O Matic Corp A two-compartment mixing and dispensing device
US3985608A (en) 1969-05-03 1976-10-12 Rolf Saxholm Supporting element for use in microbiological, serological, immunological, clinical-chemical and similar laboratory work
US3674028A (en) 1969-06-04 1972-07-04 Ims Ltd Multi-mix
DE1939315B2 (de) 1969-08-01 1973-03-15 Etablissement Dentaire Ivoclar, Schaan (Liechtenstein) Mehrkammeriger behaelter fuer die aufnahme von miteinander reagierenden substanzen zur herstellung von gebrauchsfertigen dentalpraeparaten
US3651990A (en) 1969-10-23 1972-03-28 Edward J Cernei Container for keeping liquids in separate condition and commingling and dispensing the same
US3694455A (en) 1970-11-19 1972-09-26 Smith Kline French Lab Acyloxyalkyl amidobenzimidazoles
BE794915A (fr) 1972-02-03 1973-08-02 Inge Spa Dispositif de fermeture pour bouteilles et analogues, permettant de conserver separement des ingredients a melanger au moment de l'emploi
US3799426A (en) 1972-04-12 1974-03-26 D Lacy Container
US3815580A (en) 1972-08-31 1974-06-11 C Oster Apparatus for and method of collecting and preserving cytologic samples
US3846077A (en) 1972-09-18 1974-11-05 P Ohringer Liquid sample collection tube
US3831742A (en) 1972-10-16 1974-08-27 Pennwalt Corp Dental mixing capsule
US4184483A (en) 1973-05-08 1980-01-22 U.S. Medical Research & Development, Inc. Method of and apparatus for collecting cultures
IT994127B (it) 1973-08-03 1975-10-20 Sigma Tau Ind Farmaceuti Dispositivo per la chiusura ermetica di contenitori dotato di perforatore e di goccimetro
FR2279378A1 (fr) * 1974-07-22 1976-02-20 Chibret Laboratoires Recipient pour la reconstitution de produits lyophilises ou pulverulents
FR2293182A1 (fr) 1974-12-04 1976-07-02 Feaster William Dispositif pour la preparation de prelevements de sang et de substances similaires
USD244555S (en) 1975-03-25 1977-05-31 Greiner Electronic Ag Covered test tube
USD246600S (en) 1975-05-06 1977-12-06 Japan Medical Supply Co., Ltd. Test tube
FR2342914A1 (fr) 1976-03-02 1977-09-30 Oreal Dispositif de conditionnement de deux produits isoles l'un de l'autre avant la distribution
USD246698S (en) 1976-05-28 1977-12-20 Morris Glenn H Reversible safety cap and screw cap for containers
US4081356A (en) 1976-09-24 1978-03-28 The United States Of America As Represented By The Department Of Health, Education And Welfare Fecalator, an apparatus and method for concentration of parasite eggs and larvae
USD255092S (en) 1976-11-18 1980-05-27 Wong Johnson N S Combined vial and supporting base
USD252612S (en) 1976-12-08 1979-08-14 Starplex Inc. Container for blood samples or the like
US4140489A (en) 1977-02-07 1979-02-20 Lee Sun Y Test tube for easy enumeration and cultivation of anaerobic and facultatively anaerobic microorganisms
US4170798A (en) 1977-05-05 1979-10-16 University Of Alabama In Birmingham Apparatus for homogenizing and handling biowaste and other materials in isolation
US4089432A (en) 1977-05-06 1978-05-16 The Upjohn Company Vial and closure
US4102451A (en) 1977-05-25 1978-07-25 Eli Lilly And Company Mixing vial
US4150950A (en) 1977-09-28 1979-04-24 Corning Glass Works Transport system for clinical specimens
US4131016A (en) 1977-11-09 1978-12-26 The Kendall Company Peak flow measuring device
US4200100A (en) 1978-04-20 1980-04-29 Aluminum Company Of America Additive transfer unit with piercing member having a penetratable protective tip
USD256053S (en) 1978-04-20 1980-07-22 The Kendall Company Specimen device
US4195730A (en) 1978-06-20 1980-04-01 General Foods Corporation Container having separate storage facilities for two materials
US4221291A (en) 1978-06-20 1980-09-09 General Foods Corporation Container having separate storage facilities for two materials
US4175008A (en) 1978-06-26 1979-11-20 Bio-Pharmaceutical Packaging Corp. Culture specimen collection and transport package
US4217798A (en) 1979-04-30 1980-08-19 The United States Of America As Represented By The Department Of Health, Education And Welfare Automated test tube stopper remover
US4301812A (en) 1979-12-12 1981-11-24 The Kendall Company Midstream sampling device
US4312950A (en) 1980-03-31 1982-01-26 Hillwood Corporation Disposable swab and culture unit
US4340147A (en) 1980-11-03 1982-07-20 Mack-Wayne Plastics Company Cap with built in piercing device
US4418702A (en) 1981-01-12 1983-12-06 Metpath Inc. Method and apparatus for collecting saliva
JPS5896365U (ja) 1981-12-22 1983-06-30 日本電気株式会社 フアクシミリ原稿送信用キヤリアシ−ト
USD274132S (en) 1982-01-25 1984-06-05 Pacer Technology And Resources, Inc. Container cap
US4465183A (en) 1982-07-19 1984-08-14 Kao Soap Co., Ltd. Two-part liquid container with breakable partition
USD277736S (en) 1982-09-20 1985-02-26 Pacer Technology & Resources, Inc. Container cap
US4505433A (en) 1982-09-28 1985-03-19 Selenke William M Tissue grinding and transporting device
USD287570S (en) 1983-05-26 1987-01-06 A/S Nunc Combined sample tube, screw cap and marking plug
JPS604433U (ja) 1983-06-21 1985-01-12 株式会社吉野工業所 二液混合容器
DE3426739A1 (de) 1984-07-20 1986-01-30 Robert Finke KG, 5950 Finnentrop Zwei-komponenten-packung
DE3327615C2 (de) 1983-07-30 1985-08-14 Robert Finke KG, 5950 Finnentrop Zwei-Komponenten-Packung
USD285115S (en) 1983-12-05 1986-08-12 Terumo Medical Corporation Collector for capillary blood
USD286546S (en) 1984-01-14 1986-11-04 Shachihata Industrial Co., Ltd. Felt tip pen
US4583971A (en) 1984-02-10 1986-04-22 Travenol European Research And Development Centre (Teradec) Closed drug delivery system
US4832917A (en) 1984-04-19 1989-05-23 California State University Fullerton Foundation Grommetted system for liquid scintillation vials
US4678559A (en) 1984-07-23 1987-07-07 Andreas Szabados Test specimen container for pasty specimen material
US4761379A (en) 1984-08-09 1988-08-02 Becton, Dickinson And Company Biological specimen collection device
US4634003A (en) 1984-08-22 1987-01-06 Suntory Limited Container for accommodating two kinds of liquids
US4589548A (en) 1984-12-06 1986-05-20 Biomedical Polymers, Inc. Sputum collection apparatus
USD296241S (en) 1985-04-15 1988-06-14 Miskinis Robert J Laboratory glass joint
US4663161A (en) 1985-04-22 1987-05-05 Mannino Raphael J Liposome methods and compositions
IT1185850B (it) 1985-08-02 1987-11-18 Zambon Spa Tappo serbatoio contagocce per flaconi
EP0215735B1 (de) 1985-09-05 1990-06-13 Dr. Ernst Gräub AG Veterinärmedizinischer Reagentiensatz für Schnelltest zur Bestimmung des Blutcalciumgehaltes
JPH0672837B2 (ja) 1985-12-25 1994-09-14 アンドレアス・スツアバドス ペースト状試料物質用の検査容器
US4727985A (en) 1986-02-24 1988-03-01 The Boc Group, Inc. Mixing and dispensing apparatus
US5030559A (en) 1986-04-01 1991-07-09 Board Of Regents, The University Of Texas System Methods and compositions for the identification of metastatic human tumors
JPH0338704Y2 (de) 1986-04-30 1991-08-15
DE3751516T2 (de) 1986-04-30 1996-02-15 Igen Inc Elektrochemilumineszenz-testverfahren.
GB8614084D0 (en) 1986-06-10 1986-07-16 Serono Diagnostics Ltd Immunoassay
US4741346A (en) 1986-06-16 1988-05-03 Evergreen Industries, Inc. Speciman collector
JPH0627578Y2 (ja) 1986-10-28 1994-07-27 ア−ス製薬株式会社 混合する物質を収容する容器用キャップ
US4935342A (en) 1986-12-01 1990-06-19 Syngene, Inc. Method of isolating and purifying nucleic acids from biological samples
EP0273015A3 (de) 1986-12-24 1988-10-05 Vifor S.A. Behälter mit Aufnahmevorrichtung für ein Fläschchen
USD303710S (en) 1986-12-29 1989-09-26 Kontes Glass Company Connector for joining laboratory glassware
US4753358A (en) 1987-03-02 1988-06-28 Promega Corporation Vial cap coupling device
USD310264S (en) 1987-03-04 1990-08-28 Nalge Company Cryogenic vial
CA1317860C (en) 1987-04-01 1993-05-18 Daniel Louis Kacian Techniques for preparing specimens for bacterial assays
US4927605A (en) 1987-04-22 1990-05-22 Wadley Technologies, Inc. Specimen collection and sampling container
US5128104A (en) 1987-04-27 1992-07-07 Murphy Harold R Cuvette for automated testing machine
US4785931A (en) 1987-09-24 1988-11-22 Letica Corporation Molded plastic closure having integral stacking support ribs and rupturable mix compartments
US4918178A (en) 1987-10-22 1990-04-17 Wisconsin Alumni Research Foundation Test for Johne's disease
US4999288A (en) 1987-10-28 1991-03-12 Gds Technology, Inc. Test composition and method for the determination of anilides
WO1989005456A1 (en) 1987-12-01 1989-06-15 Biotope, Inc. Methods and devices for conducting assays
EP0395731A4 (en) 1988-01-11 1993-12-01 Microprobe Corporation Oligonucleotide probes for detection of periodontal pathogens
EP0338591A3 (de) 1988-04-21 1991-09-04 Microprobe Corporation Verfahren zum Extrahieren vom Nukleinsäuren
US5091316A (en) 1988-06-09 1992-02-25 Becton, Dickinson And Company Biological sample collection and transport device
CA1340208C (en) 1988-06-09 1998-12-15 James F. Monthony Biological sample collection and transport device
USD330011S (en) 1988-06-13 1992-10-06 Marr Electric Limited Twist-on electrical connector
DE68902025T2 (de) 1988-09-01 1992-12-10 Capsulit Srl Verschluss fuer flaschen und dergleichen, der einen behaelter mit durchstossbarem boden enthaelt.
US5756126A (en) 1991-05-29 1998-05-26 Flinders Technologies Pty. Ltd. Dry solid medium for storage and analysis of genetic material
US5807527A (en) * 1991-05-29 1998-09-15 Flinders Technologies Pty. Ltd. Solid medium and method for DNA storage
US5496562A (en) * 1988-10-05 1996-03-05 Flinders Technologies Pty Ltd Solid medium and method for DNA storage
CA1326809C (en) 1988-11-01 1994-02-08 C. Albert Kezes Swab retaining vial cap
USD318727S (en) 1988-11-04 1991-07-30 Sun Brokers, Inc. Vial
USD325444S (en) 1988-12-13 1992-04-14 Terumo Kabushiki Kaisha Blood collecting tube
US5139031A (en) 1989-09-18 1992-08-18 La Mina Ltd. Method and device for cytology and microbiological testing
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5140043A (en) * 1989-04-17 1992-08-18 Duke University Stable ascorbic acid compositions
US5152965A (en) 1989-06-02 1992-10-06 Abbott Laboratories Two-piece reagent container assembly
US4932081A (en) 1989-08-11 1990-06-12 Becton, Dickinson And Company Sputum cup
US5128247A (en) 1989-08-14 1992-07-07 Board Of Regents, The University Of Texas System Methods for isolation of nucleic acids from eukaryotic and prokaryotic sources
ES2047947T3 (es) 1989-09-14 1994-03-01 Becton Dickinson France Contenedor alargado que tiene dos compartimientos separados, dispuestos uno en prolongacion del otro.
US5479937A (en) 1989-09-21 1996-01-02 Epitope, Inc. Oral collection device
US5335673A (en) 1989-09-21 1994-08-09 Epitope, Inc. Oral collection device and method for immunoassay
US5849890A (en) 1990-06-11 1998-12-15 Nexstar Pharmaceuticals, Inc. High affinity oligonucleotide ligands to chorionic gonadotropin hormone and related glycoprotein hormones
JPH0492141A (ja) 1990-08-03 1992-03-25 Bridgestone Corp トーショナルダンパ
US5066463A (en) 1990-10-01 1991-11-19 Chang Maw Guay Multiple-purpose fecal examination apparatus
DE4034036C2 (de) 1990-10-26 1994-03-03 Diagen Inst Molekularbio Vorrichtung und Verfahren zur Isolierung von Nukleinsäuren aus Zellsuspensionen
JPH04187077A (ja) 1990-11-22 1992-07-03 Shimadzu Corp 核酸の抽出精製装置
US5283038A (en) 1990-12-18 1994-02-01 Saliva Diagnostic Systems, Inc. Fluid sampling and testing device
US5393496A (en) 1990-12-18 1995-02-28 Saliva Diagnostic Systems, Inc. Saliva sampling device and sample adequacy system
US5268148A (en) 1990-12-18 1993-12-07 Saliva Diagnostic Systems, Inc. Saliva sampling device and sample adequacy system
US5380492A (en) 1990-12-18 1995-01-10 Seymour; Eugene H. Sampling device and sample adequacy system
US5478722A (en) 1991-02-17 1995-12-26 The Curators Of The University Of Missouri Preserved cell preparations for flow cytometry and immunology
US5196182A (en) 1991-05-08 1993-03-23 Streck Laboratories, Inc. Tissue fixative
AR244884A1 (es) 1991-06-25 1993-11-30 Saliva Diagnostic Systems Inc Dispositivo tomador de muestras y disposicion medidora de muestras.
USD338956S (en) 1991-10-04 1993-08-31 Abbott Laboratories Protective overcap for a stick holder for medicament
JPH0599923A (ja) 1991-10-11 1993-04-23 Nitto Denko Corp ヒトヘモグロビンの検出方法及びそれに用いる便溶解用緩衝液
US5658531A (en) 1991-11-01 1997-08-19 The University Of Birmingham Assay device
AU664050B2 (en) 1991-12-18 1995-11-02 Becton Dickinson & Company Process for lysing mycobacteria
US5512440A (en) 1991-12-18 1996-04-30 Becton Dickinson And Company Process for lysing Mycobacteria
DE4204012A1 (de) 1992-02-12 1993-08-19 Ulrich Prof Dr Zimmermann Mitogenfreie substanz, deren herstellung und verwendung
USD344804S (en) 1992-02-20 1994-03-01 Ralph Muniz Vial for holding an expandable liquid
DE69333289T2 (de) 1992-04-01 2004-08-26 The Johns Hopkins University School Of Medicine Verfahren zur bestimmung von säugetier nukleinsäuren aus stuhlproben und dafür benötigte reagenzien
JP2579257Y2 (ja) 1992-05-30 1998-08-20 有限会社佐藤化成工業所 採便容器
DE69314462T2 (de) 1992-08-24 1998-05-20 Dade Microscan Inc Abdichtbarer behälter zum konservieren und behandeln analytischer proben
WO1994012657A1 (en) 1992-11-20 1994-06-09 Katcher Harold L Direct-phenol pcr, rt and rt-pcr methods
AU5694694A (en) 1992-12-02 1994-06-22 Denis F. Hochstrasser A method for detecting growing cells using translationally controlled tumor protein p21
US5843654A (en) 1992-12-07 1998-12-01 Third Wave Technologies, Inc. Rapid detection of mutations in the p53 gene
USD362184S (en) 1993-02-17 1995-09-12 Unilever Patent Holdings B.V. Overcap for a microbiological culture bottle
US5422273A (en) 1993-03-23 1995-06-06 Baal Medical Products, Inc. Cell collection apparatus
US5494646A (en) 1993-04-14 1996-02-27 Seymour; Eugene H. Sampling device and sample adequacy system
US5477863A (en) 1993-04-14 1995-12-26 Grant; Michael A. Collection kit with a sample collector
JP2599763Y2 (ja) 1993-04-20 1999-09-20 株式会社資生堂 ２種類の収納物を混合するための容器
US5384096A (en) 1993-05-12 1995-01-24 Becton, Dickinson And Company Microcollection tube assembly
USD357985S (en) 1993-05-27 1995-05-02 Becton Dickinson And Company Microcollection tube
US5409826A (en) 1993-06-08 1995-04-25 Coulter Corporation Preserved, non-infectious control cells prepared by the modulation or modification of normal cells
US5396986A (en) 1993-06-16 1995-03-14 Special Metals Corporation Mixing capsule having three tubular members
DE4321904B4 (de) 1993-07-01 2013-05-16 Qiagen Gmbh Verfahren zur chromatographischen Reinigung und Trennung von Nucleinsäuregemischen
US5330048A (en) 1993-07-09 1994-07-19 Habley Medical Technology Corporation Controlled access mixing vial
USD355606S (en) 1993-08-10 1995-02-21 Comar, Inc. Neck of a glass vial
USD383214S (en) 1993-08-18 1997-09-02 Brennan V Jack Combined cap and vial
USD372093S (en) 1993-09-10 1996-07-23 Sampson Richard K Circular tubing connector handle
USD375160S (en) 1993-09-10 1996-10-29 Sampson Richard K Tubing connector handle
US5624554A (en) 1993-11-22 1997-04-29 Biomedical Polymers, Inc. Collection and transfer device
CA2176496C (en) 1993-11-29 1999-09-28 Kathleen A. Clark Method for extracting nucleic acids from a wide range of organisms
US5567309A (en) 1994-02-14 1996-10-22 Alcott Chromatography, Inc. Self-filtration cap
US5714341A (en) 1994-03-30 1998-02-03 Epitope, Inc. Saliva assay method and device
GB2288384B (en) 1994-04-07 1997-06-25 Johnson & Johnson Medical Two-component packages
CA2147593C (en) 1994-04-22 2008-07-29 Hyman C. Birnboim Dual purpose tissue fixative
US5643767A (en) 1994-05-02 1997-07-01 The Rockefeller University Process for isolating cellular components
US5814442A (en) 1994-06-10 1998-09-29 Georgetown University Internally controlled virion nucleic acid amplification reaction for quantitation of virion and virion nucleic acid
AU2907995A (en) 1994-06-23 1996-01-19 Dade International Inc. Method for the rapid isolation of nucleic acid
USD362623S (en) 1994-07-13 1995-09-26 Inter-Continental Nail Products Fingernail glue bottle cap
FR2722765B1 (fr) 1994-07-25 1996-08-23 Oreal Recipient permettant le stockage d'au moins deux produits, le melange de ces produits et la distribution du melange ainsi obtenu
USD367114S (en) 1994-09-07 1996-02-13 Pasteur Sanofi Diagnostics Specimen sample cup for use in an automatic analyzer
USD379663S (en) 1994-09-23 1997-06-03 Unipath Limited Testing instrument
US5490971A (en) 1994-10-25 1996-02-13 Sippican, Inc. Chemical detector
DE9417612U1 (de) 1994-11-03 1995-01-05 Kloth, Bernd, 22399 Hamburg Probenabnahmegerät
KR19980701950A (ko) 1994-12-23 1998-06-25 에드워드 에이. 맥더모 2세, 로이드 제이. 오울드 분석, 리셉터 단백질 및 리간드
WO1996020397A1 (en) 1994-12-23 1996-07-04 The University Of Newcastle Research Associates Limited Atmometer
USD383851S (en) 1994-12-30 1997-09-16 Evergreen Industries, Inc. Leak proof vial for microscope slides
RU2101354C1 (ru) 1995-01-31 1998-01-10 Ставропольский научно-исследовательский противочумный институт Способ получения нуклеиновых кислот bacillus anthracis
US6423550B1 (en) 1995-03-30 2002-07-23 Ortho Pharmaceutical Corporation Home oral fluid sample collection device and package for mailing of such device
USD392187S (en) 1995-05-18 1998-03-17 Beeson And Sons Limited Container closure
US7422902B1 (en) 1995-06-07 2008-09-09 The University Of British Columbia Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
EP1007935B1 (de) 1995-06-07 2006-08-30 Adeza Biomedical Corporation Flüssigkeitssammelgerät und -methode
US5736322A (en) 1995-06-07 1998-04-07 Epitope, Inc. Synthetic oral fluid standard
US5786228A (en) * 1995-06-07 1998-07-28 Biex, Inc. Fluid collection kit and method
WO1997000213A1 (en) 1995-06-14 1997-01-03 Paul Anthony Byrne A closure containing a fluid for mixture with a beverage
US5827675A (en) * 1995-07-12 1998-10-27 Charm Sciences, Inc. Test apparatus, system and method for the detection of test samples
US5945515A (en) 1995-07-31 1999-08-31 Chomczynski; Piotr Product and process for isolating DNA, RNA and proteins
DE19530132C2 (de) 1995-08-16 1998-07-16 Max Planck Gesellschaft Verfahren zur Reinigung, Stabilisierung oder Isolierung von Nukleinsäuren aus biologischen Materialien
DE69632904T2 (de) 1995-08-21 2004-11-18 Palma Bee'z Research Institute Co., Ltd. Kopräzipitat und methode zur extraktion von nukleinsäuren
GB9518156D0 (en) 1995-09-06 1995-11-08 Medical Res Council Method of isolating cells
US5556544A (en) 1995-09-08 1996-09-17 Didier; Emmanuel R. Concentrator & filter
NO954667D0 (no) 1995-11-17 1995-11-17 Dagfinn Oegreid Fremgangsmåte til deteksjon av Ki-ras mutasjoner
WO1997021102A1 (en) 1995-12-05 1997-06-12 Branch Donald R Methods for the early detection of hiv infection
US6133036A (en) * 1995-12-12 2000-10-17 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Preservation of liquid biological samples
GB9525414D0 (en) 1995-12-13 1996-02-14 Rocep Lusol Holdings A device for releasing a fluid into a liquid in a container
US6551791B1 (en) * 1995-12-21 2003-04-22 University Of Florida Rapid diagnostic method for distinguishing allergies and infections and nasal secretion collection unit
WO1997025798A1 (en) 1996-01-11 1997-07-17 Mrj, Inc. System for controlling access and distribution of digital property
US5830154A (en) 1996-01-11 1998-11-03 Epitope, Inc. Device for collecting substances for testing
JPH09193977A (ja) 1996-01-19 1997-07-29 Anest Iwata Corp 低圧スプレーガン加圧容器の加圧エア供給機構
GB9602025D0 (en) 1996-02-01 1996-04-03 Amersham Int Plc Nucleoside analogues
US6667053B1 (en) 1996-02-16 2003-12-23 Elan Pharmaceuticals, Inc. D and L etherlipid stereoisomers and liposomes
US5707860A (en) 1996-03-12 1998-01-13 Becton Dickinson And Company Vehicle for delivery of particles to a sample
USD388519S (en) 1996-04-02 1997-12-30 Charm Sciences, Inc. Pocket-size sanitation test kit
EP0891550A1 (de) 1996-04-05 1999-01-20 The Johns Hopkins University School Of Medicine Verfahren zur anreicherung von seltenen zellen
WO1997042344A1 (de) 1996-05-03 1997-11-13 Institut Für Medizinische Molekulardiagnostik Gbrmbh Verfahren zur dns-analytik von blut und mittel zur durchführung des verfahrens
US6020196A (en) 1996-05-09 2000-02-01 Baxter International Inc. Devices for harvesting and homogenizing adipose tissue containing autologous endothelial cells
US5736355A (en) 1996-05-13 1998-04-07 Steris Corporation Self contained biological indicator
FI102642B (fi) 1996-06-19 1999-01-15 Orion Diagnostica Oy Reaktioastian tai vastaavan tulppa
US5939262A (en) 1996-07-03 1999-08-17 Ambion, Inc. Ribonuclease resistant RNA preparation and utilization
WO1998003265A1 (fr) 1996-07-18 1998-01-29 Kyoritsu Chemical-Check Lab., Corp. Recipient a reactif tenant dans un bouchon, pour reactifs d'analyse
US5980834A (en) 1996-07-25 1999-11-09 The United States Of America As Represented By The Secretary Of Commerce Sample storage devices
WO1998005795A1 (en) 1996-08-02 1998-02-12 The Center For Blood Research, Inc. Enrichment of dendritic cells from blood
USD385793S (en) 1996-08-05 1997-11-04 Revlon Consumer Products Corporation Combined container and cap
US5735320A (en) 1996-08-21 1998-04-07 The Sherwin-Williams Company Dispenser for a two-part composition
DE59712894D1 (de) 1996-08-26 2007-12-27 Invitek Biotechnik & Biodesign Verfahren zum nachweis klinisch relevanter veränderungen der dns-sequenz des ki-ras-onkogens, seine verwendung und testkit zur früherkennung von tumoren
US5871905A (en) 1996-09-04 1999-02-16 Epitope, Inc. Reduction of false positives in oral-fluid based immunoassays
DE19635833C2 (de) 1996-09-04 1998-08-06 Henkel Kgaa Zwei-Komponenten-Behälter
WO1998012351A1 (de) 1996-09-19 1998-03-26 Roth W Kurt Verfahren zur reinigung und gegebenenfalls analyse von nukleinsäuren aus biologischen proben
US5935864A (en) 1996-10-07 1999-08-10 Saliva Diagnostic Systems Inc. Method and kit for collecting samples of liquid specimens for analytical testing
USD412990S (en) 1996-10-07 1999-08-17 Cortecs (Uk) Limited Medical test device
JPH10132824A (ja) 1996-10-28 1998-05-22 Eiken Chem Co Ltd ヘモグロビンの安定化方法
US6228323B1 (en) 1996-12-13 2001-05-08 Alcon Laboratories, Inc. Multi-purpose compositions containing an alkyl-trypsin and methods of use in contact lens cleaning and disinfecting
US6113257A (en) 1996-12-26 2000-09-05 M.L.I.S. Projects Ltd. Two-compartment container
US5921396A (en) 1997-01-21 1999-07-13 Brown, Jr.; Jacob T. Specimen collection kit for mailing and method of using same
IT1292677B1 (it) 1997-02-28 1999-02-11 Bormioli Metalplast Spa Confezione per mantenere separati dei prodotti prima dell'uso.
US6277646B1 (en) 1997-05-05 2001-08-21 Dade Behring Inc. Fluid specimen collecting and testing apparatus
WO1998038917A1 (en) 1997-03-05 1998-09-11 Point Of Care Technologies, Inc. Fluid specimen collecting and testing apparatus
US6524795B1 (en) 1997-03-10 2003-02-25 Interleukin Genetics, Inc. Diagnostics for cardiovascular disorders
US6720141B1 (en) 1999-11-01 2004-04-13 Interleukin Genetics, Inc. Diagnostics and therapeutics for restenosis
US5817630A (en) * 1997-03-18 1998-10-06 Austin Nutriceutical Corporation Glutathione antioxidant eye drops
US5935804A (en) 1997-03-21 1999-08-10 Laine; Roger A. Method for detecting eubacteria in biological samples with catalytically inactive murein binding enzymes
US5788652A (en) 1997-03-24 1998-08-04 S&H Diagnostics, Inc. Blood sample collection device
JPH10273161A (ja) 1997-03-26 1998-10-13 Mitsubishi Materials Corp 容器用キャップおよび容器
WO1998044158A1 (en) 1997-03-28 1998-10-08 Epitope, Inc. Simultaneous collection of dna and non-nucleic analytes from oral fluids
EP0967985B1 (de) 1997-04-07 2005-06-15 The Iams Company Verfahren zur verbesserung des glukosemetabolismus, sättigungsgefühles, und nährstoffabsorption in haustieren
US5939259A (en) 1997-04-09 1999-08-17 Schleicher & Schuell, Inc. Methods and devices for collecting and storing clinical samples for genetic analysis
ES2163268T3 (es) 1997-05-15 2002-01-16 R & D Injector Ag Sistema de recipiente con dos componentes.
US6613881B1 (en) 1997-05-20 2003-09-02 Corixa Corporation Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
MX203911B (es) 1997-05-21 2001-08-24 Pablo Andres Robles Gonzalez Aparato contenedor de substancias solubles en medios fluidos y metodo para la preparacion de mezclas en sitio.
USD401697S (en) 1997-05-21 1998-11-24 Abbott Laboratories Container
USD412107S (en) 1997-05-27 1999-07-20 Cebal S.A. Combined tube and cap
JPH10332734A (ja) 1997-05-29 1998-12-18 Japan Aviation Electron Ind Ltd 加速度計
US6268136B1 (en) 1997-06-16 2001-07-31 Exact Science Corporation Methods for stool sample preparation
AU7816898A (en) 1997-06-16 1999-01-04 Exact Laboratories, Inc. Methods for stool sample preparation
US6310195B1 (en) 1997-06-24 2001-10-30 Imclone Systems Incorporated Nucleic acid encoding a lectin-derived progenitor cell preservation factor
US6071745A (en) 1997-06-27 2000-06-06 Bio-Rad Laboratories Method and formulation for lyophilizing cultured human cells to preserve RNA and DNA contained in cells for use in molecular biology experiments
FR2765859B1 (fr) 1997-07-08 1999-09-24 Oreal Dispositif pour le conditionnement de deux composants
US5869328A (en) 1997-08-08 1999-02-09 Cdc Technologies, Inc. Cuvette for performing a diagnostic test on a specimen
US5829696A (en) 1997-08-27 1998-11-03 Michelle S. DeStefano Sealed grinding and homogenizing apparatus
US6190875B1 (en) 1997-09-02 2001-02-20 Insight Strategy & Marketing Ltd. Method of screening for potential anti-metastatic and anti-inflammatory agents using mammalian heparanase as a probe
JP2000146957A (ja) * 1997-10-13 2000-05-26 Kikkoman Corp 検体採取具及び拭取検査用器具
US6786330B2 (en) 1997-10-14 2004-09-07 Biogaia Ab Two-compartment container
US6120985A (en) 1997-10-31 2000-09-19 Bbi Bioseq, Inc. Pressure-enhanced extraction and purification
US6875617B2 (en) 1997-11-07 2005-04-05 Geno Technology, Inc. Agent for protein precipitation, a method of protein precipitation, a method of protein assay using protein precipitation agent, and a kit for protein assay
USD402766S (en) 1997-11-13 1998-12-15 Bayer Corporation Puck
US5968746A (en) 1997-11-26 1999-10-19 Schneider; David R. Method and apparatus for preserving human saliva for testing
WO1999029904A2 (en) 1997-12-10 1999-06-17 Sierra Diagnostics, Inc. Methods and reagents for preservation of dna in bodily fluids
WO1999032616A2 (de) 1997-12-18 1999-07-01 Invitek Gmbh Verfahren zur isolierung von kurz- und langkettigen nukleinsäuren
JP3719572B2 (ja) 1997-12-19 2005-11-24 栄研器材株式会社 環境衛生検査用の検体採取容器
US5941380A (en) 1998-01-10 1999-08-24 Rothman; David Device for dispensing flowable material
EP0939118A1 (de) 1998-02-20 1999-09-01 Universiteit Maastricht Verfahren zur Isolierung von DNA und RNA aus Stuhlproben
US5927549A (en) 1998-03-20 1999-07-27 Aptargroup, Inc. Dispensing structure with frangible membrane for separating two products
DE19812657A1 (de) 1998-03-23 1998-12-24 Wella Ag Zweikomponentenbehälter
US6303081B1 (en) 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
SE511864C2 (sv) 1998-04-01 1999-12-06 Medscand Medical Ab Spatel för provtagning innefattande perforeringar
US5950819A (en) 1998-05-08 1999-09-14 Sellars; Andy Storage, admixing, and dispensing system
US5984141A (en) 1998-05-20 1999-11-16 Gibler; Gregory A. Beverage storage and mixing device
FR2781500B1 (fr) 1998-07-23 2000-09-08 Bio Merieux Dispositif perfectionne et procede de lyse de micro-organismes
US6204375B1 (en) 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
AU4934099A (en) 1998-08-04 2000-02-28 Center For Advanced Science And Technology Incubation, Ltd. Method for enzymatic amplification of nucleic acid
AU5231599A (en) 1998-08-19 2000-03-14 David S. Soane Container cap for release of contents contained therein
US6562300B2 (en) 1998-08-28 2003-05-13 Becton, Dickinson And Company Collection assembly
US6022339A (en) 1998-09-15 2000-02-08 Baxter International Inc. Sliding reconstitution device for a diluent container
US6777210B1 (en) 1998-09-24 2004-08-17 Ambion, Inc. Method and reagents for inactivating ribonucleases RNase A, RNase I and RNase T1
US6176836B1 (en) * 1998-09-25 2001-01-23 David Trudil Biological sample collection kit
USD437786S1 (en) 1998-10-09 2001-02-20 Henkel Kommanditgesellschaft Auf Aktien Combined bottle and cap
US6003728A (en) 1998-10-22 1999-12-21 Aptargroup, Inc. Dispensing structure with an openable member for separating two products
US6152296A (en) 1998-11-06 2000-11-28 Shih; Kuang-Sheng Additive holder for a pet bottle
WO2000029618A1 (en) 1998-11-12 2000-05-25 University Of Virginia Patent Foundation Non-invasive detection of helicobacter pylori infection
US20010008614A1 (en) * 1998-11-16 2001-07-19 Jack L. Aronowitz Sample collection system and method of use thereof
US6039198A (en) 1998-11-24 2000-03-21 Owens-Illinois Closure Inc. Pierce and cut closure
US7666609B1 (en) 1998-12-01 2010-02-23 Shanghai Cp Guojian Pharmaceutical Co. Ltd. Method and composition for diagnosis of melanocytic lesions
DE19856064C2 (de) 1998-12-04 2000-11-30 Invitek Gmbh Universelles Verfahren zur Isolierung von DNA aus beliebigen Ausgangsmaterialien
DE19900638C2 (de) 1999-01-11 2002-12-19 Max Planck Gesellschaft Methode zur Isolierung von DNA aus biologischen Materialien
GB9903767D0 (en) 1999-02-18 1999-04-14 Univ Glasgow Receptor assay
FR2790005B1 (fr) 1999-02-22 2004-01-30 Commissariat Energie Atomique Procede de fabrication de morpholino-nucleotides, et utilisation de ceux-ci pour l'analyse et le marquage de sequences d'acides nucleiques
ES2269102T3 (es) * 1999-02-25 2007-04-01 Exact Sciences Corporation Procedimientos para conservar la integridad del adn.
US6299842B1 (en) 1999-03-05 2001-10-09 Meridian Bioscience, Inc. Biological sampling and storage container utilizing a desiccant
US20020004206A1 (en) 1999-04-09 2002-01-10 Berger Barry M. Methods of screening for disease
WO2000066606A1 (en) 1999-04-30 2000-11-09 Whatman, Inc. Substrate including anionic detergent for purifying nucleic acid
US6270970B1 (en) 1999-05-14 2001-08-07 Promega Corporation Mixed-bed solid phase and its use in the isolation of nucleic acids
US6716396B1 (en) 1999-05-14 2004-04-06 Gen-Probe Incorporated Penetrable cap
WO2000078150A1 (en) 1999-06-21 2000-12-28 Symbollon Corporation Iodine germicides that continuously generate free molecular iodine
US6350578B1 (en) 1999-06-25 2002-02-26 The Regents Of The University Of California Method of quantitating dsDNA
DE19933458B4 (de) 1999-07-15 2015-08-20 Eppendorf Ag Einrichtungen und Systeme zum Handhaben von Flüssigkeitsproben
USD432245S (en) 1999-07-27 2000-10-17 Becton Dickinson And Company Collection assembly with a specimen label
US6242188B1 (en) * 1999-07-30 2001-06-05 Applied Gene Technologies, Inc. Sample processing to release nucleic acids for direct detection
USD425625S (en) 1999-08-06 2000-05-23 Becton, Dickinson And Company Specimen sampling tube
USD425618S (en) 1999-08-06 2000-05-23 Becton, Dickinson And Company Specimen collection device
US6235010B1 (en) 1999-08-06 2001-05-22 Becton Dickinson And Company Closed system specimen collection container
US6170719B1 (en) 1999-08-06 2001-01-09 Becton Dickinson And Company Medical safety closure
USD445908S1 (en) 1999-08-06 2001-07-31 Becton, Dickinson And Company Stackable tube assembly
USD424440S (en) 1999-08-06 2000-05-09 Becton, Dickinson And Company Tube cap
US6849403B1 (en) 1999-09-08 2005-02-01 Exact Sciences Corporation Apparatus and method for drug screening
US6586177B1 (en) 1999-09-08 2003-07-01 Exact Sciences Corporation Methods for disease detection
FR2798291B1 (fr) 1999-09-10 2005-01-14 Pasteur Institut Compositions acellulaires immunogenes et compositions acellulaires vaccinales contre bacillus anthracis
DE60044977D1 (de) 1999-09-24 2010-10-28 Ambion Inc Cocktail von nukleaseinhibitoren
DE19950884A1 (de) 1999-10-22 2001-04-26 Wella Ag Kombinationsverpackung
US7041484B1 (en) 1999-10-29 2006-05-09 National Research Council Of Canada Starch branching enzymes
AU1122701A (en) 1999-10-29 2001-05-14 National Research Council Of Canada Starch branching enzymes
WO2001034844A1 (en) 1999-11-10 2001-05-17 Ligochem, Inc. Method for isolating dna from a proteinaceous medium and kit for performing method
AU6066799A (en) 1999-11-26 2001-05-31 Lily Hsu Container device for separately enclosing two different substances
US6471069B2 (en) 1999-12-03 2002-10-29 Becton Dickinson And Company Device for separating components of a fluid sample
AU2064201A (en) 1999-12-06 2001-06-12 Eukarion, Inc. Carbohydrate-aminated glycoproteins
US6409528B1 (en) 1999-12-06 2002-06-25 Becton, Dickinson And Company Device and method for collecting, preparation and stabilizing a sample
US6919174B1 (en) 1999-12-07 2005-07-19 Exact Sciences Corporation Methods for disease detection
EP1238106A2 (de) 1999-12-07 2002-09-11 Exact Sciences Corporation Vorrichtung und verfahren zur drogenuntersuchung unter verwendung der nukleinsäureanalyse
US6224922B1 (en) 1999-12-16 2001-05-01 Mark J. Fonte Drink colorizer
US6489172B1 (en) 2000-01-05 2002-12-03 Varian, Inc. Saliva sampling device
US6832994B2 (en) 2000-01-24 2004-12-21 Bracco Diagnostics Inc. Table top drug dispensing vial access adapter
US7005266B2 (en) 2000-02-04 2006-02-28 Qiagen Gmbh Nucleic acid isolation from stool samples and other inhibitor-rich biological materials
KR20020073580A (ko) 2000-02-09 2002-09-27 바스프 악티엔게젤샤프트 신규 연장효소 유전자 및 다가불포화 지방산의 제조 방법
DE10006662A1 (de) 2000-02-15 2001-08-23 Antigen Produktions Gmbh Gefäß zur Nukleinsäureanalytik
AU2001241738A1 (en) 2000-02-25 2001-09-03 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
USD438800S1 (en) 2000-03-10 2001-03-13 Alcoa Closure Systems International Closure
USD442090S1 (en) 2000-03-29 2001-05-15 Pechiney Plastic Packaging, Inc. Closure
FR2808276B1 (fr) 2000-04-26 2004-04-02 Renaud Nalin Procede d'extraction indirecte de l'adn d'organismes non cultivables et adn susceptible d'etre obtenu par ledit procede
WO2001083751A2 (en) 2000-04-28 2001-11-08 Sangamo Biosciences, Inc. Methods for binding an exogenous molecule to cellular chromatin
US6627152B1 (en) 2000-04-29 2003-09-30 Branan Medical Corp. Fluid testing apparatus
USD457247S1 (en) 2000-05-12 2002-05-14 Gen-Probe Incorporated Cap
US6495534B2 (en) 2000-05-15 2002-12-17 Pharmacia & Upjohn Spa Stabilized aqueous suspensions for parenteral use
DE10031236A1 (de) 2000-06-27 2002-01-10 Qiagen Gmbh Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien
US6548256B2 (en) 2000-07-14 2003-04-15 Eppendorf 5 Prime, Inc. DNA isolation method and kit
JP4599684B2 (ja) 2000-07-26 2010-12-15 株式会社島津製作所 糞便からの核酸精製法
USD447812S1 (en) 2000-08-24 2001-09-11 Becton Dickinson And Company Collection tube assembly
AUPR038300A0 (en) 2000-09-26 2000-10-19 Cryovac Australia Pty Ltd Reclosable container
CU23095A1 (es) 2000-11-07 2005-11-18 Cnic Ct Nac Investigaciones Proceso para la tipificación rápida de microorganismos y juego de reactivos empleado
US6602718B1 (en) 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
CA2428864C (en) 2000-11-08 2011-04-12 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
US7029840B2 (en) 2000-11-15 2006-04-18 Becton, Dickinson And Company Method for preservation of cells and nucleic acid targets
EP1207208A3 (de) 2000-11-15 2003-12-10 Becton Dickinson and Company Methode zur Erhaltung von Zellen und Nukleinsäurezielmolekülen
JP3639897B2 (ja) 2000-11-17 2005-04-20 幸孝 古川 医療検体保管容器
DE60018431T2 (de) 2000-11-24 2005-12-29 Chemunex S.A. Verfahren zum Einfangen luftgebundener Mikroorganismen mittels wasserlöslicher Polymere
US7001724B1 (en) 2000-11-28 2006-02-21 Applera Corporation Compositions, methods, and kits for isolating nucleic acids using surfactants and proteases
US6503716B1 (en) * 2000-11-28 2003-01-07 Pe Corporation (Ny) Compositions and methods for extracting a nucleic acid
WO2002044691A2 (en) 2000-11-28 2002-06-06 Mcmaster University Sputum fixative and methods and uses therefor
US6527110B2 (en) 2000-12-01 2003-03-04 Brett Moscovitz Device for storing and dispensing a substance by mating with a container and associated methods
US6533113B2 (en) 2000-12-01 2003-03-18 Brett Moscovitz System, devices and methods for storing and mixing substances
US6911308B2 (en) 2001-01-05 2005-06-28 Exact Sciences Corporation Methods for detecting, grading or monitoring an H. pylori infection
US6939672B2 (en) 2001-01-15 2005-09-06 Cytyc Corporation Nucleic acid extraction solution and use thereof
DE10102338A1 (de) 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Expression von Biosynthesegenen in pflanzlichen Samen unter Verwendung von neuen multiplen Expressionskonstrukten
US6634234B1 (en) 2001-02-10 2003-10-21 Vega Grieshaber Kg Adjustable measurement head and a level measurement device and method employing it
US6428962B1 (en) * 2001-02-12 2002-08-06 Dna Analysis, Inc. Nucleic acid collection barrier method and apparatus
DE10109354A1 (de) 2001-02-27 2002-09-05 Icon Genetics Ag Rekombinante virale Schaltersysteme
EP1795263B2 (de) 2001-03-09 2017-08-23 Gen-Probe Incorporated Verfahren zum Entnehmen von Flüssigkeit aus einem Behälter mit durchdringbarem Verschluss
US6833259B2 (en) 2001-03-19 2004-12-21 Council Of Scientific And Industrial Research ‘Pseudomonas stutzeri’ strain and process for preparation of xylanase
US7957907B2 (en) 2001-03-30 2011-06-07 Sorenson Molecular Genealogy Foundation Method for molecular genealogical research
CA2445587A1 (en) 2001-04-26 2002-11-07 Boston Biomedica, Inc. Multichamber device and uses thereof for processing of biological samples
US6543612B2 (en) 2001-05-21 2003-04-08 3M Innovative Properties Company Container for compositions made of two or more components
USD455908S1 (en) 2001-07-31 2002-04-23 Lausan Chung-Hsin Liu Single-user swing chair
WO2003016552A2 (en) 2001-08-20 2003-02-27 Whatman, Inc. Dna purification and recovery from high particulate and solids samples
USD467665S1 (en) 2001-09-28 2002-12-24 Orasure Technologies, Inc. Test device
US7879293B2 (en) 2001-09-28 2011-02-01 Orasure Technologies, Inc. Sample collector and test device
USD470240S1 (en) 2001-09-28 2003-02-11 Orasure Technologies, Inc. Handle for a sample collector
USD467349S1 (en) 2001-09-28 2002-12-17 Orasure Technologies, Inc. Analyzer
US7148343B2 (en) 2001-10-12 2006-12-12 Gentra Systems, Inc. Compositions and methods for using a solid support to purify RNA
CA2463317A1 (en) 2001-10-12 2003-04-24 Gentra Systems, Inc. Compositions and methods for using a solid support to purify rna
JP4213588B2 (ja) 2001-10-12 2009-01-21 ベクトン・ディキンソン・アンド・カンパニー 生体試料を輸送する方法及び装置
US7893228B2 (en) 2001-10-12 2011-02-22 Qiagen North American Holdings, Inc. Compositions and methods for using a solid support to purify RNA
US6617137B2 (en) 2001-10-15 2003-09-09 Molecular Staging Inc. Method of amplifying whole genomes without subjecting the genome to denaturing conditions
US7297485B2 (en) 2001-10-15 2007-11-20 Qiagen Gmbh Method for nucleic acid amplification that results in low amplification bias
AUPR848001A0 (en) 2001-10-29 2001-11-15 Dixon, Brodie Container/bottle cap with a storage compartment
BR0105971A (pt) 2001-11-09 2003-08-05 Gustavo Senna Chelles Embalagem para multicomponentes
US20030109548A1 (en) 2001-11-09 2003-06-12 Royt Paulette W. Compositions and methods of treating iron excess
AU2002365229A1 (en) * 2001-11-15 2003-09-02 Whatman, Inc. Methods and materials for detecting genetic material
US20030162204A1 (en) 2001-12-04 2003-08-28 Dave Smith Alcohol detection assembly
AU2002357107B2 (en) 2001-12-06 2008-01-10 Biocontrol Systems, Inc. Sample collection and testing system
USD471639S1 (en) 2001-12-17 2003-03-11 Kimberly-Clark Worldwide, Inc. Tool for handling a specimen
US20030170694A1 (en) 2001-12-21 2003-09-11 Daniel Wall Stabilized nucleic acids in gene and drug discovery and methods of use
US6634243B1 (en) 2002-01-14 2003-10-21 Rapid Medical Diagnostics Corporation Sample testing device
DE10202147A1 (de) 2002-01-17 2003-09-18 Birkmayer Gesundheitsprodukte Kunststoff-Flaschenverschluss
US6880771B2 (en) 2002-02-01 2005-04-19 Monsanto Technology Llc Axially reciprocating tubular ball mill grinding device and method
JP3848201B2 (ja) 2002-03-18 2006-11-22 株式会社エルメックス 拭き取り検査キット
DE10219117C1 (de) 2002-04-29 2003-10-30 Adnagen Ag Verfahren zur Stabilisierung von RNS und Verwendungen von Stabilisierungspuffern
EP1527172B1 (de) 2002-05-17 2008-11-26 Molzym GmbH & Co. KG Methode für die extraktion und aufreinigung von nukleinsäuren
DE10222133A1 (de) 2002-05-17 2003-12-04 Gl Biotech Gmbh Verfahren zur Nukleinsäure-Extraktion und Nukleinsäure-Reinigung
US20030215954A1 (en) 2002-05-17 2003-11-20 Cockerill Franklin R. Nucleic acid recovery reagents and methods
AU2003242353A1 (en) 2002-05-21 2003-12-02 Arkray, Inc. Method of effecting lysis of acid-fast bacteria and method of performing gene amplification or detection therewith
US6852495B2 (en) 2002-06-06 2005-02-08 Shimadzu Corporation Process of extracting nucleic acid and process of simultaneously carrying out extraction and purification of nucleic acid
JP4092139B2 (ja) 2002-06-06 2008-05-28 株式会社島津製作所 核酸抽出法
JP4092141B2 (ja) 2002-06-07 2008-05-28 株式会社島津製作所 核酸抽出同時精製法
US7482116B2 (en) * 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
USD471234S1 (en) 2002-06-25 2003-03-04 Easthill Industry Ltd. Pen cap
US20040018575A1 (en) 2002-07-29 2004-01-29 Craig Rappin Sample preparation device and method
US20040018120A1 (en) 2002-07-29 2004-01-29 Craig Rappin Sample preparation device and method
EP1391520A1 (de) 2002-08-20 2004-02-25 Becton Dickinson and Company Verfahren zum Schutz von Zellen und Nukleinsäure-Targets
JP2006514823A (ja) 2002-08-20 2006-05-18 ミレニアム ファーマスーティカルズ インク 子宮頸癌の同定、評価、予防および治療を行うための組成物、キットおよび方法
US6913932B2 (en) 2002-08-23 2005-07-05 Beckman Coulter, Inc. Formaldehyde-ammonium salt complexes for the stabilization of blood cells
US20040197845A1 (en) 2002-08-30 2004-10-07 Arjang Hassibi Methods and apparatus for pathogen detection, identification and/or quantification
US7537778B2 (en) 2002-09-26 2009-05-26 W. Neudorff Gmbh Kg Pesticidal compositions and methods
EP1563091B2 (de) 2002-10-04 2012-06-27 GE Healthcare Bio-Sciences Corp. Verfahren und materialien zur verwendung chemischer verbindungen als hilfsmittel zur nukleinsäurelagerung auf medien von nukleinsäurereinigungssystemen
AU2002951977A0 (en) 2002-10-10 2002-10-24 Leo Engineering Pty Ltd Improvements to two-part vessels
IL152905A0 (en) 2002-11-17 2003-06-24 Univ Ramot Dopaminergic markers induction in neuronal-like cells isolated from adult human bone marrow stromal cells: implications for novel gene therapy strategy for parkinsons disease
CA101498S (en) 2002-12-06 2004-01-20 Dna Genotek Inc Saliva collection tube
US7214484B2 (en) 2002-12-17 2007-05-08 Sigma-Aldrich Co. Compositions and methods for nucleic acid extraction from biological samples
CN2598551Y (zh) 2002-12-27 2004-01-14 珠海亿胜生物制药有限公司 用于密封与混合两种或两种以上不同物质的连接器
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
JP2004222795A (ja) 2003-01-20 2004-08-12 Naigai Kasei Kk 薬剤混注用器具及びその製造方法
WO2004080597A2 (en) 2003-02-05 2004-09-23 Iquum, Inc. Sample processing tubule
US20040157219A1 (en) 2003-02-06 2004-08-12 Jianrong Lou Chemical treatment of biological samples for nucleic acid extraction and kits therefor
TW587693U (en) 2003-03-14 2004-05-11 Mau-Guei Jang Attaching and stirring type quantitative excrements inspection device
US7267980B1 (en) 2003-04-04 2007-09-11 Research & Diagnostic Systems, Inc. Stabilizing solution for cells and tissues
US6994211B2 (en) 2003-04-12 2006-02-07 Young Kook Cho Cap device for mixing different kinds of materials separately contained therein and in bottle
US6935493B2 (en) 2003-04-12 2005-08-30 Young Kook Cho Cap device for mixing different kinds of materials separately contained therein and in bottle
US6974024B2 (en) 2003-04-12 2005-12-13 Young Kook Cho Cap device for mixing different kinds of materials separately contained therein and in bottle
CA2465804A1 (en) 2003-04-28 2004-10-28 Elena Trkulja Aerosol collection cap and container
JP2004338751A (ja) 2003-05-15 2004-12-02 Nippon Tansan Gas Co Ltd 原料を隔離して収容する容器の封止機構及び封止方法
DE10324913A1 (de) 2003-05-30 2004-12-30 Sarstedt Ag & Co. Verfahren und Vorrichtung zur Stuhlprobenentnahme
JP4842807B2 (ja) 2003-06-02 2011-12-21 ベクトン・ディキンソン・アンド・カンパニー カートリッジ付きの医薬マイクロデバイス給送システム
US20050096563A1 (en) * 2003-11-05 2005-05-05 Greg Liang Oral fluid sampling device and method
US20050239045A1 (en) 2003-12-08 2005-10-27 Arkray Inc. Microorganism or cell collecting method, and microorganism or cell collecting implement used for the method
WO2006096973A1 (en) 2005-03-16 2006-09-21 Dna Genotek Inc. Compositions and method for storage of nucleic acid from bodily fluids
CA118249S (en) 2005-12-09 2007-08-22 Dna Genotek Inc Vial
BRPI0619596B8 (pt) 2005-12-09 2021-06-22 Dna Genotek Inc sistema de recipiente para o armazenamento liberável de líquido, método para combinar líquido com amostra biológica e kit para a coleta e armazenamento de amostra.
CA113861S (en) 2005-12-09 2007-08-22 Dna Genotek Inc Vial
EP2074430B1 (de) * 2006-08-17 2011-03-16 DIAneering Diagnostics Engineering and Research GmbH Verfahren und mittel zur bestimmung der blutplättchenfunktion und zur diagnose von mit blutplättchen verbundenen störungen und herz-kreislauf-erkrankungen
EP2066686A4 (de) 2006-10-06 2010-07-14 Dna Genotek Inc Stabilisierungszusammensetzungen und verfahren zur extraktion von ribonukleinsäure
EP2326934B1 (de) 2008-08-21 2017-04-19 DNA Genotek Inc. Probenaufnahmevorrichtung
CA127470S (en) 2008-08-21 2010-06-21 Dna Genotek Inc Sample collector
WO2010075265A2 (en) * 2008-12-23 2010-07-01 The Government Of The United States Of America , As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention Lung aerosol collection device
US20100241091A1 (en) * 2009-03-20 2010-09-23 Mr. Tan Wu (Owners in common 1/2) Sputum collecting device
DK2430420T3 (da) * 2009-05-14 2020-03-16 Dna Genotek Inc Lukning, beholderanordning og fremgangsmåde til anvendelse deraf
USD631350S1 (en) 2009-09-01 2011-01-25 Dna Genotek Inc. Double-ended closure
WO2011116481A1 (en) 2010-03-25 2011-09-29 Dna Genotek Inc. Sample collection tool
USD640794S1 (en) 2010-03-26 2011-06-28 Dna Genotek Inc. Sample collection tool
MX347611B (es) 2011-06-19 2017-05-04 Abogen Inc Dispositivos, soluciones y metodos para recoleccion de muestras.
EP3096812A4 (de) 2014-01-20 2017-06-21 Abogen, Inc. Vorrichtungen, lösungen und verfahren zur probenentnahme
ES2880310T3 (es) 2014-03-07 2021-11-24 Dna Genotek Inc Composición y método para estabilizar ácidos nucleicos en muestras biológicas
CA2947704A1 (en) 2014-04-10 2015-10-15 Dna Genotek Inc. Method and system for microbial lysis using periodates
US20170072393A1 (en) 2014-05-14 2017-03-16 Dna Genotek Inc. Device for Collecting, Transporting and Storing Biomolecules from a Biological Sample
USD743571S1 (en) 2014-05-27 2015-11-17 Dna Genotek Inc. Sample collection device
JP2017516477A (ja) 2014-05-27 2017-06-22 ディーエヌエー ジェノテック インク 頑丈な微生物の生存能力を安定化および維持するための組成物および方法
USD743044S1 (en) 2015-01-16 2015-11-10 Dna Genotek Inc. Tube restrictor for expressing fluid from a swab
EP3256849A4 (de) 2015-02-09 2018-12-05 Abogen, Inc. Vorrichtungen, lösungen und verfahren für anwendungen im zusammenhang mitprobeentnahme, analyse und diagnose
EP3464589A4 (de) 2016-05-31 2020-02-26 DNA Genotek Inc. Zusammensetzung, system und verfahren zur entfernung von detergenzien aus wässrigen lösungen
USD850647S1 (en) 2016-08-19 2019-06-04 Dna Genotek Inc. False bottom tube with cap and plug
US20180235206A1 (en) * 2017-02-17 2018-08-23 Oasis Diagnostics Corporation Compositions and methods for stabilizing dna in saliva samples
WO2018170186A1 (en) * 2017-03-15 2018-09-20 Ancestry.Com Dna, Llc Sample collection device and method
US20170182196A1 (en) * 2017-03-17 2017-06-29 Nilin Patel Apparatus configured for collection and sterilization of expectorates

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