DE60329188D1 - Arzneizubereitungen bestehend aus arzneimitteln in halb-geordneter form und polymeren - Google Patents
Arzneizubereitungen bestehend aus arzneimitteln in halb-geordneter form und polymerenInfo
- Publication number
- DE60329188D1 DE60329188D1 DE60329188T DE60329188T DE60329188D1 DE 60329188 D1 DE60329188 D1 DE 60329188D1 DE 60329188 T DE60329188 T DE 60329188T DE 60329188 T DE60329188 T DE 60329188T DE 60329188 D1 DE60329188 D1 DE 60329188D1
- Authority
- DE
- Germany
- Prior art keywords
- polymers
- medicinal products
- drug preparations
- oriented form
- preparations consisting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40308702P | 2002-08-12 | 2002-08-12 | |
PCT/IB2003/003465 WO2004014342A1 (en) | 2002-08-12 | 2003-07-31 | Pharmaceutical compositions of semi-ordered drugs and polymers |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60329188D1 true DE60329188D1 (de) | 2009-10-22 |
Family
ID=31715934
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60329188T Expired - Lifetime DE60329188D1 (de) | 2002-08-12 | 2003-07-31 | Arzneizubereitungen bestehend aus arzneimitteln in halb-geordneter form und polymeren |
Country Status (24)
Country | Link |
---|---|
US (2) | US8257739B2 (de) |
EP (2) | EP2111856A3 (de) |
JP (1) | JP2006500349A (de) |
CN (1) | CN1681479A (de) |
AR (1) | AR040969A1 (de) |
AT (1) | ATE442130T1 (de) |
AU (1) | AU2003249474A1 (de) |
BR (1) | BR0313428A (de) |
CA (1) | CA2496441C (de) |
DE (1) | DE60329188D1 (de) |
ES (1) | ES2333318T3 (de) |
GT (1) | GT200300170A (de) |
IL (1) | IL166411A0 (de) |
MX (1) | MXPA05000977A (de) |
NO (1) | NO20050419L (de) |
PA (1) | PA8579801A1 (de) |
PE (1) | PE20040865A1 (de) |
PL (1) | PL375345A1 (de) |
PT (1) | PT1530457E (de) |
RU (1) | RU2005103625A (de) |
TW (1) | TW200406224A (de) |
UY (1) | UY27929A1 (de) |
WO (1) | WO2004014342A1 (de) |
ZA (1) | ZA200500470B (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5767429B2 (ja) * | 1999-11-12 | 2015-08-19 | アッヴィ・インコーポレイテッド | 固体分散剤中の結晶化阻害剤 |
JP2004534812A (ja) * | 2001-06-22 | 2004-11-18 | ファイザー・プロダクツ・インク | 薬物および中性ポリマーの分散物の医薬組成物 |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
CA2577852A1 (en) * | 2004-08-31 | 2006-03-09 | Pfizer Products Inc. | Pharmaceutical dosage forms comprising a low-solubility drug and a polymer |
EP1855652B1 (de) | 2005-01-28 | 2015-12-02 | Bend Research, Inc | Trocknung von arzneimittelhaltigen teilchen |
US8834929B2 (en) | 2006-07-21 | 2014-09-16 | Bend Research, Inc. | Drying of drug-containing particles |
WO2008133102A1 (ja) * | 2007-04-20 | 2008-11-06 | Daido Chemical Corporation | 新規乾式固体分散体用基剤、該基剤を含有する固体分散体及び該分散体を含有する組成物 |
US20100048912A1 (en) | 2008-03-14 | 2010-02-25 | Angela Brodie | Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens, In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity |
US20110312916A1 (en) | 2009-02-05 | 2011-12-22 | Tokai Pharmaceuticals, Inc. | Novel prodrugs of steroidal cyp17 inhibitors/antiandrogens |
EP2366378A1 (de) | 2010-03-01 | 2011-09-21 | Dexcel Pharma Technologies Ltd. | Donepezilformulierungen mit verzögerter Freisetzung |
US8591944B2 (en) | 2011-03-08 | 2013-11-26 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
TW201311240A (zh) * | 2011-07-21 | 2013-03-16 | 必治妥美雅史谷比公司 | 非晶形哌啶基化合物之生物可利用組合物 |
BR112015019807B1 (pt) | 2013-03-07 | 2020-12-08 | Dow Global Technologies Llc | acetato succinato de hidroxipropil metilcelulose, composição, dispersão sólida, forma de dosagem e envoltório de cápsula |
JP6267239B2 (ja) | 2013-03-07 | 2018-01-24 | ダウ グローバル テクノロジーズ エルエルシー | 極めて低粘度の新規エステル化セルロースエーテル |
US9890220B2 (en) | 2013-03-07 | 2018-02-13 | Dow Global Technologies Llc | Esterified cellulose ethers of very high molecular weight |
SG11201507093WA (en) | 2013-03-14 | 2015-10-29 | Univ Maryland Baltimore Office Of Technology Transfer | Androgen receptor down-regulating agents and uses thereof |
EP2832723B1 (de) * | 2013-07-29 | 2017-02-15 | Zentiva, a.s. | Stabilisierte amorphe Formen von Saxagliptin |
RU2016104643A (ru) | 2013-08-12 | 2017-09-19 | Токай Фармасьютикалз, Инк. | Биомаркёры для лечения неопластических заболеваний с применением нацеленных на андроген методов лечения |
CA2962719A1 (en) | 2014-10-31 | 2016-05-06 | Bend Research Inc. | Process for forming active domains dispersed in a matrix |
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CA1146866A (en) | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Process for the production of sustained release pharmaceutical composition of solid medical material |
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DE3612212A1 (de) | 1986-04-11 | 1987-10-15 | Basf Ag | Verfahren zur herstellung von festen pharmazeutischen formen |
JPS6314724A (ja) * | 1986-07-08 | 1988-01-21 | Tooa Eiyoo Kk | プラゾシン製剤 |
JPH02149518A (ja) * | 1988-11-30 | 1990-06-08 | Nikken Chem Co Ltd | 経口投与用薬剤 |
DK546289D0 (da) | 1989-11-02 | 1989-11-02 | Danochemo As | Carotenoidpulvere |
US5552160A (en) | 1991-01-25 | 1996-09-03 | Nanosystems L.L.C. | Surface modified NSAID nanoparticles |
US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
US5399363A (en) | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
EP0580860B2 (de) | 1991-04-16 | 2004-12-15 | Nippon Shinyaku Company, Limited | Verfahren zur herstellung einer festen dispersion |
DE4140184C2 (de) | 1991-12-05 | 1995-12-21 | Alfatec Pharma Gmbh | Akutform für ein Flurbiprofen enthaltendes Arzneimittel |
DE4140185C2 (de) | 1991-12-05 | 1996-02-01 | Alfatec Pharma Gmbh | Ein 2-Arylpropionsäurederivat in Nanosolform enthaltendes Arzneimittel und seine Herstellung |
US5876754A (en) | 1992-01-17 | 1999-03-02 | Alfatec-Pharma Gmbh | Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies |
US5340591A (en) | 1992-01-24 | 1994-08-23 | Fujisawa Pharmaceutical Co., Ltd. | Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine |
JP3265680B2 (ja) | 1992-03-12 | 2002-03-11 | 大正製薬株式会社 | 経口製剤用組成物 |
US5811547A (en) | 1992-10-14 | 1998-09-22 | Nippon Shinyaju Co., Ltd. | Method for inducing crystalline state transition in medicinal substance |
US5916596A (en) | 1993-02-22 | 1999-06-29 | Vivorx Pharmaceuticals, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
DE4316537A1 (de) | 1993-05-18 | 1994-11-24 | Basf Ag | Zubereitungen in Form fester Lösungen |
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DE4327063A1 (de) | 1993-08-12 | 1995-02-16 | Kirsten Dr Westesen | Ubidecarenon-Partikel mit modifizierten physikochemischen Eigenschaften |
DE4329446A1 (de) | 1993-09-01 | 1995-03-02 | Basf Ag | Verfahren zur Herstellung von feinteiligen Farb- oder Wirkstoffzubereitungen |
DE19509807A1 (de) | 1995-03-21 | 1996-09-26 | Basf Ag | Verfahren zur Herstellung von Wirkstoffzubereitungen in Form einer festen Lösung des Wirkstoffs in einer Polymermatrix sowie mit diesem Verfahren hergestellte Wirkstoffzubereitungen |
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US5585108A (en) | 1994-12-30 | 1996-12-17 | Nanosystems L.L.C. | Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays |
US5662883A (en) | 1995-01-10 | 1997-09-02 | Nanosystems L.L.C. | Microprecipitation of micro-nanoparticulate pharmaceutical agents |
US5560932A (en) | 1995-01-10 | 1996-10-01 | Nano Systems L.L.C. | Microprecipitation of nanoparticulate pharmaceutical agents |
US5665331A (en) * | 1995-01-10 | 1997-09-09 | Nanosystems L.L.C. | Co-microprecipitation of nanoparticulate pharmaceutical agents with crystal growth modifiers |
US5716642A (en) | 1995-01-10 | 1998-02-10 | Nano Systems L.L.C. | Microprecipitation of nanoparticulate pharmaceutical agents using surface active material derived from similar pharmaceutical agents |
US5569448A (en) | 1995-01-24 | 1996-10-29 | Nano Systems L.L.C. | Sulfated nonionic block copolymer surfactants as stabilizer coatings for nanoparticle compositions |
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US5874029A (en) | 1996-10-09 | 1999-02-23 | The University Of Kansas | Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent |
JPH09309828A (ja) * | 1996-03-18 | 1997-12-02 | Eisai Co Ltd | 溶解を改善した薬剤組成物 |
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JP2007513937A (ja) | 2003-12-09 | 2007-05-31 | ファイザー インコーポレイテッド | Hivプロテアーゼ阻害剤を含む組成物 |
-
2003
- 2003-07-31 DE DE60329188T patent/DE60329188D1/de not_active Expired - Lifetime
- 2003-07-31 AT AT03784384T patent/ATE442130T1/de not_active IP Right Cessation
- 2003-07-31 PL PL03375345A patent/PL375345A1/xx not_active Application Discontinuation
- 2003-07-31 AU AU2003249474A patent/AU2003249474A1/en not_active Abandoned
- 2003-07-31 CA CA2496441A patent/CA2496441C/en not_active Expired - Fee Related
- 2003-07-31 JP JP2004527196A patent/JP2006500349A/ja active Pending
- 2003-07-31 PT PT03784384T patent/PT1530457E/pt unknown
- 2003-07-31 BR BR0313428-8A patent/BR0313428A/pt not_active Withdrawn
- 2003-07-31 RU RU2005103625/15A patent/RU2005103625A/ru not_active Application Discontinuation
- 2003-07-31 MX MXPA05000977A patent/MXPA05000977A/es unknown
- 2003-07-31 EP EP09007816.3A patent/EP2111856A3/de not_active Withdrawn
- 2003-07-31 EP EP03784384A patent/EP1530457B1/de not_active Revoked
- 2003-07-31 ES ES03784384T patent/ES2333318T3/es not_active Expired - Lifetime
- 2003-07-31 WO PCT/IB2003/003465 patent/WO2004014342A1/en active Application Filing
- 2003-07-31 CN CNA038213486A patent/CN1681479A/zh active Pending
- 2003-08-05 UY UY27929A patent/UY27929A1/es not_active Application Discontinuation
- 2003-08-05 US US10/636,834 patent/US8257739B2/en active Active
- 2003-08-06 PA PA20038579801A patent/PA8579801A1/es unknown
- 2003-08-06 GT GT200300170A patent/GT200300170A/es unknown
- 2003-08-08 PE PE2003000793A patent/PE20040865A1/es not_active Application Discontinuation
- 2003-08-11 AR ARP030102902A patent/AR040969A1/es not_active Application Discontinuation
- 2003-08-11 TW TW092121979A patent/TW200406224A/zh unknown
-
2005
- 2005-01-18 ZA ZA200500470A patent/ZA200500470B/xx unknown
- 2005-01-20 IL IL16641105A patent/IL166411A0/xx unknown
- 2005-01-25 NO NO20050419A patent/NO20050419L/no not_active Application Discontinuation
-
2012
- 2012-08-23 US US13/593,263 patent/US8491933B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1530457A1 (de) | 2005-05-18 |
US20040156905A1 (en) | 2004-08-12 |
AU2003249474A1 (en) | 2004-02-25 |
JP2006500349A (ja) | 2006-01-05 |
TW200406224A (en) | 2004-05-01 |
UY27929A1 (es) | 2004-03-31 |
BR0313428A (pt) | 2005-06-28 |
WO2004014342A1 (en) | 2004-02-19 |
ZA200500470B (en) | 2006-07-26 |
ES2333318T3 (es) | 2010-02-19 |
CA2496441A1 (en) | 2004-02-19 |
CA2496441C (en) | 2010-03-16 |
EP2111856A3 (de) | 2014-09-10 |
EP1530457B1 (de) | 2009-09-09 |
US8257739B2 (en) | 2012-09-04 |
ATE442130T1 (de) | 2009-09-15 |
EP2111856A2 (de) | 2009-10-28 |
PA8579801A1 (es) | 2004-02-16 |
US20120322805A1 (en) | 2012-12-20 |
PL375345A1 (en) | 2005-11-28 |
US8491933B2 (en) | 2013-07-23 |
AR040969A1 (es) | 2005-04-27 |
GT200300170A (es) | 2004-05-12 |
PT1530457E (pt) | 2009-11-06 |
MXPA05000977A (es) | 2005-05-16 |
IL166411A0 (en) | 2006-01-15 |
RU2005103625A (ru) | 2005-08-20 |
NO20050419L (no) | 2005-04-04 |
CN1681479A (zh) | 2005-10-12 |
PE20040865A1 (es) | 2004-11-25 |
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