DE60227802D1 - Mahlvorrichtung und verfahren zu deren betrieb - Google Patents
Mahlvorrichtung und verfahren zu deren betriebInfo
- Publication number
- DE60227802D1 DE60227802D1 DE60227802T DE60227802T DE60227802D1 DE 60227802 D1 DE60227802 D1 DE 60227802D1 DE 60227802 T DE60227802 T DE 60227802T DE 60227802 T DE60227802 T DE 60227802T DE 60227802 D1 DE60227802 D1 DE 60227802D1
- Authority
- DE
- Germany
- Prior art keywords
- milling
- grinding machine
- chamber
- drug
- rotated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C17/00—Disintegrating by tumbling mills, i.e. mills having a container charged with the material to be disintegrated with or without special disintegrating members such as pebbles or balls
- B02C17/18—Details
- B02C17/24—Driving mechanisms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C17/00—Disintegrating by tumbling mills, i.e. mills having a container charged with the material to be disintegrated with or without special disintegrating members such as pebbles or balls
- B02C17/16—Mills in which a fixed container houses stirring means tumbling the charge
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T409/00—Gear cutting, milling, or planing
- Y10T409/30—Milling
Landscapes
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Crushing And Grinding (AREA)
- Shovels (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Formation And Processing Of Food Products (AREA)
- Magnetic Treatment Devices (AREA)
- Disintegrating Or Milling (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29596501P | 2001-06-05 | 2001-06-05 | |
PCT/US2002/017323 WO2002098565A1 (en) | 2001-06-05 | 2002-05-31 | System and method for milling materials |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60227802D1 true DE60227802D1 (de) | 2008-09-04 |
Family
ID=23139990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60227802T Expired - Lifetime DE60227802D1 (de) | 2001-06-05 | 2002-05-31 | Mahlvorrichtung und verfahren zu deren betrieb |
Country Status (12)
Country | Link |
---|---|
US (3) | US6742734B2 (de) |
EP (1) | EP1392441B1 (de) |
JP (1) | JP4223390B2 (de) |
AT (1) | ATE401959T1 (de) |
AU (1) | AU2002312230A1 (de) |
CA (1) | CA2449490C (de) |
CY (1) | CY1108429T1 (de) |
DE (1) | DE60227802D1 (de) |
DK (1) | DK1392441T3 (de) |
ES (1) | ES2309177T3 (de) |
PT (1) | PT1392441E (de) |
WO (1) | WO2002098565A1 (de) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080102121A1 (en) * | 1998-11-02 | 2008-05-01 | Elan Pharma International Limited | Compositions comprising nanoparticulate meloxicam and controlled release hydrocodone |
US6428814B1 (en) | 1999-10-08 | 2002-08-06 | Elan Pharma International Ltd. | Bioadhesive nanoparticulate compositions having cationic surface stabilizers |
US7276249B2 (en) | 2002-05-24 | 2007-10-02 | Elan Pharma International, Ltd. | Nanoparticulate fibrate formulations |
US7198795B2 (en) | 2000-09-21 | 2007-04-03 | Elan Pharma International Ltd. | In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions |
US7998507B2 (en) | 2000-09-21 | 2011-08-16 | Elan Pharma International Ltd. | Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors |
CA2436574A1 (en) * | 2000-12-06 | 2002-06-13 | Pharmacia Corporation | Laboratory scale milling process |
US6976647B2 (en) | 2001-06-05 | 2005-12-20 | Elan Pharma International, Limited | System and method for milling materials |
AU2002312230A1 (en) * | 2001-06-05 | 2002-12-16 | Elan Pharma International Limited | System and method for milling materials |
US7758890B2 (en) | 2001-06-23 | 2010-07-20 | Lyotropic Therapeutics, Inc. | Treatment using dantrolene |
DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
DK1471887T3 (da) | 2002-02-04 | 2010-06-07 | Elan Pharma Int Ltd | Nanopartikelkompositioner der har lysozym som overfladestabiliseringsmiddel |
US7101576B2 (en) | 2002-04-12 | 2006-09-05 | Elan Pharma International Limited | Nanoparticulate megestrol formulations |
US9101540B2 (en) | 2002-04-12 | 2015-08-11 | Alkermes Pharma Ireland Limited | Nanoparticulate megestrol formulations |
AU2003241477A1 (en) | 2002-06-10 | 2003-12-22 | Elan Pharma International, Ltd. | Nanoparticulate polycosanol formulations and novel polycosanol combinations |
ATE487470T1 (de) | 2002-09-11 | 2010-11-15 | Elan Pharma Int Ltd | Gel-stabilisierte wirkstoff-zusammensetzungen in nanoteilchengrösse |
CA2513064C (en) | 2003-01-31 | 2009-11-10 | Elan Pharma International, Ltd. | Nanoparticulate topiramate formulations |
US20100297252A1 (en) | 2003-03-03 | 2010-11-25 | Elan Pharma International Ltd. | Nanoparticulate meloxicam formulations |
US8512727B2 (en) | 2003-03-03 | 2013-08-20 | Alkermes Pharma Ireland Limited | Nanoparticulate meloxicam formulations |
US7140567B1 (en) * | 2003-03-11 | 2006-11-28 | Primet Precision Materials, Inc. | Multi-carbide material manufacture and use as grinding media |
JP2007501683A (ja) | 2003-05-22 | 2007-02-01 | エラン ファーマ インターナショナル リミテッド | γ線照射によるナノ粒子活性物質分散体の滅菌法 |
EP1651189B1 (de) * | 2003-08-08 | 2008-12-03 | Elan Pharma International Limited | Neue metaxalon-zusammensetzungen |
ES2366646T3 (es) | 2003-11-05 | 2011-10-24 | Elan Pharma International Limited | Composiciones en forma de nanopartículas que tienen un péptido como estabilizante superficial. |
US7000850B2 (en) * | 2004-04-27 | 2006-02-21 | Brand New Technology Ltd. | Anti-scald water valve assembly |
BRPI0518187A (pt) | 2004-11-16 | 2008-11-04 | Elan Pharma Int Ltd | formulações de olanzapina em nanopartìcula injetáveis |
UA89513C2 (uk) * | 2004-12-03 | 2010-02-10 | Элан Фарма Интернешнл Лтд. | Стабільна композиція з наночастинок ралоксифену гідрохлориду |
EA013741B1 (ru) * | 2004-12-15 | 2010-06-30 | Элан Фарма Интернэшнл Лтд. | Дисперсии наночастиц такролимуса с повышенными растворимостью в воде и биодоступностью, способы их приготовления и применения |
US20060159767A1 (en) * | 2004-12-22 | 2006-07-20 | Elan Pharma International Limited | Nanoparticulate bicalutamide formulations |
BRPI0606434A2 (pt) * | 2005-01-06 | 2009-06-30 | Elan Pharma Int Ltd | formulações de candesartana nanoparticulada |
EP2353590A1 (de) | 2005-02-15 | 2011-08-10 | Elan Pharma International Limited | Aerosol und injizierbare Formulierung mit nanopartikulärem Benzodiazepin |
EP1855651A4 (de) * | 2005-03-03 | 2011-06-15 | Elan Pharma Int Ltd | Nanopartikelzusammensetzungen heterocyclischer amidderivate |
WO2006099121A2 (en) * | 2005-03-10 | 2006-09-21 | Elan Pharma International Limited | Formulations of a nanoparticulate finasteride, dutasteride and tamsulosin hydrochloride, and mixtures thereof |
EP1863450A1 (de) * | 2005-03-16 | 2007-12-12 | Elan Pharma International Limited | Nanoteilchenförmige leukotrien-rezeptor-antagonisten/kortikosteroid-formulierungen |
CN101198316A (zh) * | 2005-03-17 | 2008-06-11 | 伊兰制药国际有限公司 | 纳米微粒双膦酸盐组合物 |
MX2007011772A (es) | 2005-03-23 | 2007-12-05 | Elan Pharma Int Ltd | Formulaciones de antihistaminico y corticosteroide de materia en nanoparticulas. |
EP1871345B1 (de) * | 2005-04-12 | 2012-08-01 | Elan Pharma International Limited | Nanopartikuläre erlotinib formulierungen |
WO2006132752A1 (en) * | 2005-05-10 | 2006-12-14 | Elan Pharma International Limited | Nanoparticulate and controlled release compositions comprising vitamin k2 |
CA2607494A1 (en) * | 2005-05-10 | 2007-08-02 | Elan Pharma International Limited | Nanoparticulate clopidogrel formulations |
US20100028439A1 (en) * | 2005-05-23 | 2010-02-04 | Elan Pharma International Limited | Nanoparticulate stabilized anti-hypertensive compositions |
AU2006255177A1 (en) * | 2005-06-03 | 2006-12-14 | Elan Pharma International, Limited | Nanoparticulate imatinib mesylate formulations |
WO2006133045A1 (en) * | 2005-06-03 | 2006-12-14 | Elan Pharma International, Limited | Nanoparticulate benidipine compositions |
KR20080017065A (ko) * | 2005-06-03 | 2008-02-25 | 엘란 파마 인터내셔널 리미티드 | 나노입자형 아세트아미노펜 제제 |
EP1954253A4 (de) | 2005-06-08 | 2011-07-27 | Elan Pharma Int Ltd | Nanoteilchenförmige und kontrolliert freigesetzte zusammensetzungen mit cefditoren |
ATE446742T1 (de) * | 2005-06-09 | 2009-11-15 | Elan Pharma Int Ltd | Nanopartikuläre ebastinformulierungen |
BRPI0611626A2 (pt) * | 2005-06-13 | 2010-09-21 | Elan Pharma Int Ltd | formulações da combinação de nanopartìculas de clopidogrel e aspirina |
WO2006138421A2 (en) * | 2005-06-15 | 2006-12-28 | Elan Pharma International Limited | Nanoparticulate azelnidipine formulations |
US20070015719A1 (en) * | 2005-07-07 | 2007-01-18 | Elan Pharma International Limited | Nanoparticulate clarithromycin formulations |
US20070104792A1 (en) * | 2005-09-13 | 2007-05-10 | Elan Pharma International, Limited | Nanoparticulate tadalafil formulations |
CA2622758A1 (en) | 2005-09-15 | 2007-03-29 | Elan Pharma International, Limited | Nanoparticulate aripiprazole formulations |
AU2006337137B2 (en) | 2005-12-29 | 2012-06-14 | Tersera Therapeutics Llc | Multicyclic amino acid derivatives and methods of their use |
US7649098B2 (en) | 2006-02-24 | 2010-01-19 | Lexicon Pharmaceuticals, Inc. | Imidazole-based compounds, compositions comprising them and methods of their use |
US8367112B2 (en) * | 2006-02-28 | 2013-02-05 | Alkermes Pharma Ireland Limited | Nanoparticulate carverdilol formulations |
NZ545960A (en) | 2006-03-15 | 2008-04-30 | Environmental Decontamination | Milling apparatus |
MX2008015275A (es) * | 2006-05-30 | 2009-02-06 | Elan Pharma Int Ltd | Formulaciones de posaconazol en nanoparticulas. |
JP2009543797A (ja) * | 2006-07-10 | 2009-12-10 | エラン ファーマ インターナショナル,リミティド | ナノ粒子ソラフェニブ製剤 |
CA2657409A1 (en) * | 2006-07-12 | 2008-01-17 | Elan Corporation, Plc | Nanoparticulate formulations of modafinil |
ES2524556T3 (es) | 2006-10-09 | 2014-12-10 | Charleston Laboratories, Inc. | Composiciones farmacéuticas |
UA99270C2 (en) | 2006-12-12 | 2012-08-10 | Лексикон Фармасьютикалз, Инк. | 4-phenyl-6-(2,2,2-trifluoro-1-phenylethoxy)pyrimidine-based compounds and methods of their use |
DK2118123T3 (en) | 2007-01-31 | 2016-01-25 | Dana Farber Cancer Inst Inc | Stabilized p53 peptides and uses thereof |
ES2610531T3 (es) | 2007-03-28 | 2017-04-28 | President And Fellows Of Harvard College | Polipéptidos cosidos |
CA2905541C (en) | 2008-01-09 | 2020-02-11 | Charleston Laboratories, Inc. | Pharmaceutical compositions comprising an antiemetic and an opioid analgesic |
US20090197780A1 (en) * | 2008-02-01 | 2009-08-06 | Weaver Jimmie D | Ultrafine Grinding of Soft Materials |
WO2009117401A2 (en) * | 2008-03-21 | 2009-09-24 | Elan Pharama International Limited | Compositions for site-specific delivery of imatinib and methods of use |
JP6072539B2 (ja) | 2009-05-27 | 2017-02-01 | アルカーメス ファーマ アイルランド リミテッド | ナノ粒子活性物質組成物におけるフレーク状凝集の軽減 |
WO2011006012A1 (en) | 2009-07-08 | 2011-01-13 | Charleston Laboratories Inc. | Pharmaceutical compositions |
AU2010315190A1 (en) | 2009-11-05 | 2012-05-10 | Lexicon Pharmaceuticals, Inc. | Tryptophan hydroxylase inhibitors for the treatment of cancer |
AU2011215963A1 (en) | 2010-02-10 | 2012-08-02 | Lexicon Pharmaceuticals, Inc. | Tryptophan hydroxylase inhibitors for the treatment of metastatic bone disease |
US9012511B2 (en) | 2010-05-19 | 2015-04-21 | Alkermes Pharma Ireland Limited | Nanoparticulate cinacalcet compositions |
ES2711526T3 (es) | 2010-08-13 | 2019-05-06 | Aileron Therapeutics Inc | Macrociclos peptidomiméticos |
RU2639523C2 (ru) | 2011-10-18 | 2017-12-21 | Эйлерон Терапьютикс, Инк. | Пептидомиметические макроциклы и их применение |
MX362492B (es) | 2012-02-15 | 2019-01-21 | Aileron Therapeutics Inc | Macrociclos peptidomiméticos. |
JP6450192B2 (ja) | 2012-02-15 | 2019-01-09 | エイルロン セラピューティクス,インコーポレイテッド | トリアゾール架橋した、およびチオエーテル架橋したペプチドミメティック大環状化合物 |
US20130303763A1 (en) | 2012-03-30 | 2013-11-14 | Michael D. Gershon | Methods and compositions for the treatment of necrotizing enterocolitis |
AU2013337388B2 (en) | 2012-11-01 | 2018-08-02 | Aileron Therapeutics, Inc. | Disubstituted amino acids and methods of preparation and use thereof |
WO2015071841A1 (en) | 2013-11-12 | 2015-05-21 | Druggability Technologies Holdings Limited | Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them |
US10098931B2 (en) | 2014-05-15 | 2018-10-16 | Incube Labs, Llc | Pharmaceutical compositions and methods for fabrication of solid masses comprising immunoglobulins |
KR20170058424A (ko) | 2014-09-24 | 2017-05-26 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티드모방 거대고리 및 이의 용도 |
EP3294318A4 (de) | 2015-03-20 | 2019-04-03 | Aileron Therapeutics, Inc. | Peptidomimetische makrozyklen und verwendungen davon |
CN105381843B (zh) * | 2015-11-25 | 2017-08-15 | 河北新四达电机股份有限公司 | 低速大转矩永磁电机直驱式球磨机系统 |
EP3423041A4 (de) | 2016-03-04 | 2019-09-11 | Charleston Laboratories, Inc. | Pharmazeutische zusammensetzungen |
US10881135B1 (en) | 2017-11-10 | 2021-01-05 | Creative Destruction, LLC | Cyclonically cooled and filtered smoking water pipe and method |
CN109012906A (zh) * | 2018-07-10 | 2018-12-18 | 黄玉发 | 一种建筑垃圾碾压式破碎装置 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2350534A (en) * | 1942-10-05 | 1944-06-06 | Rosinger Arthur | Magnetic stirrer |
GB947530A (en) * | 1961-09-26 | 1964-01-22 | Gen Electric Co Ltd | Improvements in or relating to grinding mills, pelletising mills and like apparatus |
US4401672A (en) * | 1981-10-13 | 1983-08-30 | Regents Of The University Of Minnesota | Non-addictive narcotic antitussive preparation |
DE3345680A1 (de) | 1983-12-16 | 1985-06-20 | Gebrüder Netzsch, Maschinenfabrik GmbH & Co, 8672 Selb | Ruehrwerksmuehle |
US4645131A (en) * | 1984-12-24 | 1987-02-24 | Hailey Robert W | Powder milling method to produce fine powder sizes |
EP0249879B1 (de) * | 1986-06-20 | 1990-10-03 | Inoue Seisakusho (Mfg) Co., Ltd. | Apparat zum Dispergieren und Mahlen |
FR2608988B1 (fr) | 1986-12-31 | 1991-01-11 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules |
JPH0658069B2 (ja) * | 1987-04-03 | 1994-08-03 | 三菱電機株式会社 | 機関の補機駆動装置 |
JPH01171627A (ja) * | 1987-12-28 | 1989-07-06 | Inoue Seisakusho:Kk | 湿式媒体分散機 |
US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
NZ248813A (en) | 1992-11-25 | 1995-06-27 | Eastman Kodak Co | Polymeric grinding media used in grinding pharmaceutical substances |
TW384224B (en) | 1994-05-25 | 2000-03-11 | Nano Sys Llc | Method of preparing submicron particles of a therapeutic or diagnostic agent |
DE19533369C2 (de) * | 1995-09-09 | 1998-06-10 | Hermann Getzmann | Dispergiervorrichtung und Dispergierverfahren |
DE19613366A1 (de) * | 1996-04-03 | 1997-10-09 | Goldschmidt Ag Th | Vorrichtung zur Behandlung von Suspensionen |
US6245357B1 (en) * | 1998-03-06 | 2001-06-12 | Alza Corporation | Extended release dosage form |
JP2002534953A (ja) * | 1999-01-12 | 2002-10-15 | アイランド オアシス フローズン カクテル シーオー インク | 磁気駆動装置を含む加工装置 |
AU2002312230A1 (en) | 2001-06-05 | 2002-12-16 | Elan Pharma International Limited | System and method for milling materials |
-
2002
- 2002-05-31 AU AU2002312230A patent/AU2002312230A1/en not_active Abandoned
- 2002-05-31 DK DK02739588.8T patent/DK1392441T3/da active
- 2002-05-31 EP EP02739588A patent/EP1392441B1/de not_active Expired - Lifetime
- 2002-05-31 ES ES02739588T patent/ES2309177T3/es not_active Expired - Lifetime
- 2002-05-31 DE DE60227802T patent/DE60227802D1/de not_active Expired - Lifetime
- 2002-05-31 CA CA2449490A patent/CA2449490C/en not_active Expired - Lifetime
- 2002-05-31 JP JP2003501597A patent/JP4223390B2/ja not_active Expired - Lifetime
- 2002-05-31 PT PT02739588T patent/PT1392441E/pt unknown
- 2002-05-31 WO PCT/US2002/017323 patent/WO2002098565A1/en active Application Filing
- 2002-05-31 AT AT02739588T patent/ATE401959T1/de active
- 2002-06-04 US US10/162,333 patent/US6742734B2/en not_active Expired - Lifetime
-
2004
- 2004-04-27 US US10/832,374 patent/US20040195413A1/en not_active Abandoned
-
2007
- 2007-08-03 US US11/833,645 patent/US7575184B2/en not_active Expired - Lifetime
-
2008
- 2008-10-21 CY CY20081101175T patent/CY1108429T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE401959T1 (de) | 2008-08-15 |
US20040195413A1 (en) | 2004-10-07 |
CY1108429T1 (el) | 2014-04-09 |
JP2004535919A (ja) | 2004-12-02 |
EP1392441B1 (de) | 2008-07-23 |
ES2309177T3 (es) | 2008-12-16 |
US20080025807A1 (en) | 2008-01-31 |
PT1392441E (pt) | 2008-09-30 |
WO2002098565A1 (en) | 2002-12-12 |
US6742734B2 (en) | 2004-06-01 |
JP4223390B2 (ja) | 2009-02-12 |
CA2449490A1 (en) | 2002-12-12 |
CA2449490C (en) | 2010-10-05 |
DK1392441T3 (da) | 2010-01-25 |
EP1392441A1 (de) | 2004-03-03 |
US20020179758A1 (en) | 2002-12-05 |
AU2002312230A1 (en) | 2002-12-16 |
US7575184B2 (en) | 2009-08-18 |
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8364 | No opposition during term of opposition |