DE60218302T2 - Verfahren zur gewinnung antigenspezifischer tr1-regualtorischer lymphozyten - Google Patents
Verfahren zur gewinnung antigenspezifischer tr1-regualtorischer lymphozyten Download PDFInfo
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- DE60218302T2 DE60218302T2 DE60218302T DE60218302T DE60218302T2 DE 60218302 T2 DE60218302 T2 DE 60218302T2 DE 60218302 T DE60218302 T DE 60218302T DE 60218302 T DE60218302 T DE 60218302T DE 60218302 T2 DE60218302 T2 DE 60218302T2
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- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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- Biotechnology (AREA)
- Zoology (AREA)
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- Rheumatology (AREA)
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- Hematology (AREA)
- Diabetes (AREA)
- Cell Biology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0106231A FR2824567B1 (fr) | 2001-05-11 | 2001-05-11 | Procede d'obtention de lymphocytes tr1 regulateurs specifiques d'antigene |
| FR0106231 | 2001-05-11 | ||
| PCT/FR2002/001586 WO2002092793A1 (fr) | 2001-05-11 | 2002-05-10 | Procede d'obtention de lymphocytes tr1 regulateurs specifiques d'antigene |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60218302D1 DE60218302D1 (de) | 2007-04-05 |
| DE60218302T2 true DE60218302T2 (de) | 2007-11-15 |
Family
ID=8863160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60218302T Expired - Lifetime DE60218302T2 (de) | 2001-05-11 | 2002-05-10 | Verfahren zur gewinnung antigenspezifischer tr1-regualtorischer lymphozyten |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8076133B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1390474B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4185366B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE354641T1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2446981C (cg-RX-API-DMAC7.html) |
| DE (1) | DE60218302T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1390474T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2282425T3 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2824567B1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002092793A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6358506B1 (en) | 1997-11-05 | 2002-03-19 | University Of Southern California | Use of cytokines and mitogens to inhibit pathological immune responses |
| AU3066599A (en) | 1998-03-03 | 1999-10-18 | University Of Southern California | Use of cytokines and mitogens to inhibit graft versus host disease |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| US7541184B2 (en) | 2000-02-24 | 2009-06-02 | Invitrogen Corporation | Activation and expansion of cells |
| EP1463799A4 (en) * | 2001-12-21 | 2006-01-18 | Univ Southern California | Methods for the induction of professional and cytokine-producing regulatory cells |
| US7670781B2 (en) | 2002-01-03 | 2010-03-02 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an agent that provides a primary activation signal and another agent that provides a co-stimulatory signal |
| US7638326B2 (en) * | 2002-01-03 | 2009-12-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform |
| US7745140B2 (en) * | 2002-01-03 | 2010-06-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool |
| AU2003292137A1 (en) * | 2002-11-29 | 2004-06-23 | Maria Grazia Roncarolo | Rapamycin and il-10 for the treatment of immune diseases |
| FR2852967B1 (fr) * | 2003-03-26 | 2007-12-07 | Txcell | Procede d'obtention de cellules dendritiques et de cellules t |
| FR2856700B1 (fr) * | 2003-06-24 | 2007-06-08 | Txcell | Procede d'identification de lymphocytes tr1 regulateurs par la presence et la surexpression de molecules specifiques et ses applications |
| AU2004288646A1 (en) * | 2003-11-12 | 2005-05-26 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Use of lipopeptides for activating T lymphocytes through the skin |
| WO2005118788A2 (en) | 2004-05-27 | 2005-12-15 | The Trustees Of The University Of Pennsylvania | Novel artificial antigen presenting cells and uses therefor |
| CA2575689C (en) * | 2004-08-11 | 2013-04-02 | Txcell | Tr1 cells for use in atherosclerosis |
| WO2006050138A2 (en) * | 2004-10-29 | 2006-05-11 | Benaroya Research Institute At Virginia Mason | Methods of generating antigen-specific cd4+cd25+ regulatory t cells, compositions and methods of use |
| EP1712615A1 (en) * | 2005-04-15 | 2006-10-18 | Txcell | In vitro production of a cell population using feeder cells |
| NZ601439A (en) | 2005-06-08 | 2012-11-30 | Brigham & Womens Hospital | Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway |
| SI1739166T1 (sl) * | 2005-07-01 | 2011-11-30 | Txcell S A | PRIDOBIVANJE CELIC Tr1 SPECIFIČNIH ZA ALIMENTARNI ANTIGEN ALI AVTOGEN IZ LEVKOCITNE ALI PBMC POPULACIJE |
| CA2619735C (en) * | 2005-08-31 | 2014-05-27 | Ith Immune Therapy Holdings Ab | Treatment of inflammatory bowel disease |
| GB0603081D0 (en) * | 2006-02-15 | 2006-03-29 | Dynal Biotech Asa Oslo | Method |
| US8124408B2 (en) * | 2006-10-04 | 2012-02-28 | Janssen Pharmaceutica N.V. | Preparation of inactivated artificial antigen presenting cells and their use in cell therapies |
| KR20100063052A (ko) * | 2007-08-02 | 2010-06-10 | 아이에스에스 이뮨 시스템 스티뮬레이션 에이비 | 염증성 장 질환의 진단, 단계 구분 및 모니터링 방법 |
| JP5539886B2 (ja) | 2007-10-17 | 2014-07-02 | ティクセル | Ｔｒ１細胞、間葉系幹細胞およびその使用 |
| EP2050814A1 (en) | 2007-10-17 | 2009-04-22 | Txcell | Compositions for treating multiple sclerosis |
| EP2062970A1 (en) * | 2007-11-26 | 2009-05-27 | Txcell | Compositions for treating an intestinal inflammatory condition |
| ES2393936T3 (es) | 2008-04-28 | 2013-01-02 | Txcell | Composiciones para tratar una afección auto-inmune inflamatoria |
| EP2113560A1 (en) | 2008-04-28 | 2009-11-04 | TXCell | Compositions for treating an arthritic condition |
| JP5520961B2 (ja) | 2008-11-28 | 2014-06-11 | エモリー ユニバーシティ | 感染症および腫瘍を処置するための方法 |
| TWI605828B (zh) | 2008-12-09 | 2017-11-21 | 建南德克公司 | 抗ｐｄ-ｌ１抗體及其於增進ｔ細胞功能之用途 |
| EP2221364A1 (en) * | 2009-02-23 | 2010-08-25 | TXCell | Compositions for treating an allergic or asthmatic condition |
| EP2412802A1 (en) * | 2010-07-29 | 2012-02-01 | TXCell | IL-13 producing TR1-like cells and use thereof |
| EP2439534A1 (en) * | 2010-10-08 | 2012-04-11 | TXCell | Method for assessing the efficacy of a TR1 cell therapy in asubject |
| CA2831018A1 (en) | 2011-03-25 | 2012-10-04 | Txcell | Method for using regulatory t cells in therapy |
| EP2982746A1 (en) | 2014-08-07 | 2016-02-10 | TXCell | Regulatory T cells with therapeutic potential |
| US12343397B2 (en) | 2018-05-17 | 2025-07-01 | Regents Of The University Of Minnesota | Drug-resistant immune cells and methods of use thereof |
| WO2019237378A1 (zh) * | 2018-06-16 | 2019-12-19 | 深圳市博奥康生物科技有限公司 | 一种将CD274基因定点整合至Jurkat细胞的方法及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6277635B1 (en) * | 1992-03-04 | 2001-08-21 | Schering Corporation | Use of interleukin-10 to produce a population of suppressor cells |
| CA2245170A1 (en) * | 1996-02-08 | 1997-08-14 | The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services | Methods and compositions for transforming dendritic cells and activating t cells |
| ATE347588T1 (de) * | 1996-05-23 | 2006-12-15 | Scripps Research Inst | Systeme zur präsentation von mhc-antigenen der klasse ii und verfahren zur aktivierung von cd4?+-t-lymphozyten |
| US6746670B2 (en) * | 2000-08-15 | 2004-06-08 | Schering Corporation | Regulatory T cells; methods |
| US6670146B2 (en) * | 2000-10-04 | 2003-12-30 | Schering Corporation | Regulatory T cells; methods |
-
2001
- 2001-05-11 FR FR0106231A patent/FR2824567B1/fr not_active Expired - Fee Related
-
2002
- 2002-05-10 US US10/477,671 patent/US8076133B2/en not_active Expired - Fee Related
- 2002-05-10 AT AT02740789T patent/ATE354641T1/de not_active IP Right Cessation
- 2002-05-10 EP EP02740789A patent/EP1390474B1/fr not_active Expired - Lifetime
- 2002-05-10 DE DE60218302T patent/DE60218302T2/de not_active Expired - Lifetime
- 2002-05-10 JP JP2002589661A patent/JP4185366B2/ja not_active Expired - Fee Related
- 2002-05-10 CA CA2446981A patent/CA2446981C/fr not_active Expired - Fee Related
- 2002-05-10 DK DK02740789T patent/DK1390474T3/da active
- 2002-05-10 ES ES02740789T patent/ES2282425T3/es not_active Expired - Lifetime
- 2002-05-10 WO PCT/FR2002/001586 patent/WO2002092793A1/fr not_active Ceased
-
2007
- 2007-10-30 US US11/928,189 patent/US20080233095A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE354641T1 (de) | 2007-03-15 |
| JP4185366B2 (ja) | 2008-11-26 |
| ES2282425T3 (es) | 2007-10-16 |
| CA2446981A1 (fr) | 2003-11-21 |
| FR2824567B1 (fr) | 2003-08-08 |
| JP2004526459A (ja) | 2004-09-02 |
| EP1390474A1 (fr) | 2004-02-25 |
| WO2002092793A1 (fr) | 2002-11-21 |
| US8076133B2 (en) | 2011-12-13 |
| CA2446981C (fr) | 2012-03-20 |
| FR2824567A1 (fr) | 2002-11-15 |
| US20080233095A1 (en) | 2008-09-25 |
| DE60218302D1 (de) | 2007-04-05 |
| DK1390474T3 (da) | 2007-07-02 |
| EP1390474B1 (fr) | 2007-02-21 |
| US20040191235A1 (en) | 2004-09-30 |
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