DE60216634T2 - Gel mit mindestens einem retinoid und benzoylperoxid - Google Patents

Gel mit mindestens einem retinoid und benzoylperoxid Download PDF

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Publication number
DE60216634T2
DE60216634T2 DE60216634T DE60216634T DE60216634T2 DE 60216634 T2 DE60216634 T2 DE 60216634T2 DE 60216634 T DE60216634 T DE 60216634T DE 60216634 T DE60216634 T DE 60216634T DE 60216634 T2 DE60216634 T2 DE 60216634T2
Authority
DE
Germany
Prior art keywords
composition according
composition
benzoyl peroxide
acne
retinoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60216634T
Other languages
German (de)
English (en)
Other versions
DE60216634D1 (de
Inventor
Sandrine Orsoni
Nathalie Willcox
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma Research and Development SNC
Original Assignee
Galderma Research and Development SNC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8870899&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60216634(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Galderma Research and Development SNC filed Critical Galderma Research and Development SNC
Publication of DE60216634D1 publication Critical patent/DE60216634D1/de
Application granted granted Critical
Publication of DE60216634T2 publication Critical patent/DE60216634T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Toxicology (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60216634T 2001-12-21 2002-12-09 Gel mit mindestens einem retinoid und benzoylperoxid Expired - Lifetime DE60216634T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0116747A FR2833841B1 (fr) 2001-12-21 2001-12-21 Gel comprenant au moins un retinoide et du peroxyde de benzoyle
FR0116747 2001-12-21
PCT/FR2002/004233 WO2003055472A1 (fr) 2001-12-21 2002-12-09 Gel comprenant au moins un retinoide et du peroxyde de benzoyle

Publications (2)

Publication Number Publication Date
DE60216634D1 DE60216634D1 (de) 2007-01-18
DE60216634T2 true DE60216634T2 (de) 2007-09-27

Family

ID=8870899

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60216634T Expired - Lifetime DE60216634T2 (de) 2001-12-21 2002-12-09 Gel mit mindestens einem retinoid und benzoylperoxid
DE122008000041C Pending DE122008000041I1 (de) 2001-12-21 2002-12-09 Gel mit mindestens einem retinoid und benzoylperoxid

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE122008000041C Pending DE122008000041I1 (de) 2001-12-21 2002-12-09 Gel mit mindestens einem retinoid und benzoylperoxid

Country Status (22)

Country Link
EP (1) EP1458369B1 (enExample)
JP (2) JP4889922B2 (enExample)
KR (1) KR101014586B1 (enExample)
CN (1) CN1329025C (enExample)
AR (1) AR038026A1 (enExample)
AT (1) ATE347354T1 (enExample)
AU (2) AU2002364437B2 (enExample)
BR (1) BRPI0214264B8 (enExample)
CA (1) CA2466321C (enExample)
CY (1) CY1107583T1 (enExample)
DE (2) DE60216634T2 (enExample)
DK (1) DK1458369T3 (enExample)
ES (1) ES2275948T3 (enExample)
FR (2) FR2833841B1 (enExample)
HU (1) HU230439B1 (enExample)
MX (1) MXPA04005918A (enExample)
PL (1) PL220838B1 (enExample)
PT (1) PT1458369E (enExample)
RU (1) RU2320327C2 (enExample)
SI (1) SI1458369T1 (enExample)
WO (1) WO2003055472A1 (enExample)
ZA (1) ZA200403759B (enExample)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820186B2 (en) 2001-12-21 2010-10-26 Galderma Research & Development Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt
FR2833841B1 (fr) * 2001-12-21 2005-07-22 Galderma Res & Dev Gel comprenant au moins un retinoide et du peroxyde de benzoyle
EP1813312A3 (en) * 2002-09-05 2010-03-24 Galderma Research & Development Depigmenting composition for the skin comprising adapalene and at least one depigmenting agent
US7544674B2 (en) 2002-10-25 2009-06-09 Galderma S.A. Topical skin care composition
DE602005021238D1 (de) * 2004-11-09 2010-06-24 Imaginative Res Associates Inc Retinoidlösungen und formulierungen daraus
BRPI0614143A2 (pt) 2005-08-02 2012-11-20 Sol Gel Technologies Ltd processo para revestir um material particulado insolével em Água, sàlido, com um àxido metÁlico, material particulado revestido, composiÇço, mÉtodo para o tratamento de uma condiÇço superficial em um induvÍduo, e, uso de material particulado revestido
FR2889662B1 (fr) * 2005-08-11 2011-01-14 Galderma Res & Dev Emulsion de type huile-dans-eau pour application topique en dermatologie
FR2890314B1 (fr) * 2005-09-02 2009-03-20 Galderma Res & Dev Compositiondepigmentante de la peau comprenant de l'adapalene au moins un agent depigmentant et au moins un agent anti-inflammatoire
EP1926484A2 (en) * 2005-09-02 2008-06-04 Galderma Research & Development Depigmenting composition for the skin, comprising adapalene, at least one depigmenting agent and at least one anti-inflammatory agent
BRPI0709674A2 (pt) 2006-03-31 2011-12-06 Stiefel Research Australia Pty Ltd. gel de suspensão espumante
FR2901139B1 (fr) * 2006-05-17 2009-03-20 Galderma Res & Dev S N C Snc Compositions comprenant au moins un derive de l'acide naphtoique et du peroxyde de benzoyle, leurs procedes de preparation, et leurs utilisations
CA2656451C (en) * 2006-07-13 2015-01-27 Galderma Research & Development Composition comprising a retinoid and benzoyl peroxide
FR2903603B1 (fr) * 2006-07-13 2009-03-20 Galderma Res & Dev S N C Snc Combinaison d'adapalene et de peroxyde de benzole dans le traitement de l'acne
FR2903604B1 (fr) * 2006-07-13 2008-09-05 Galderma Res & Dev S N C Snc Composition comprenant un retinoide et du peroxyde de benzoyle
US8080537B2 (en) 2006-07-13 2011-12-20 Galderma Research & Development Combinations of adapalene and benzoyl peroxide for treating acne lesions
FR2909000B1 (fr) * 2006-11-28 2009-02-06 Galderma Res & Dev S N C Snc Compositions comprenant du peroxyde de benzoyle, au moins un derive de l'acide naphtoique et au moins un compose de type polymeres de polyurethane ou des derives de celui-ci, et leurs utilisations.
FR2910321B1 (fr) * 2006-12-21 2009-07-10 Galderma Res & Dev S N C Snc Gel creme comprenant au moins un retinoide et du peroxyde de benzole
FR2910320B1 (fr) * 2006-12-21 2009-02-13 Galderma Res & Dev S N C Snc Emulsion comprenant au moins un retinoide et du peroxyde de benzole
EP2114392B1 (en) 2007-01-30 2015-06-10 Galderma Research & Development Use of adapalene and benzoyl peroxide for the long term treatment of acne vulgaris
EA200970724A1 (ru) * 2007-02-01 2010-02-26 Сол-Джел Текнолоджиз Лтд. Композиции для местного применения, содержащие пероксид и ретиноид
ES2763829T3 (es) 2007-02-01 2020-06-01 Sol Gel Tech Ltd Método para preparar partículas que comprenden un revestimiento de óxido de metal
EP1967180A1 (de) * 2007-03-06 2008-09-10 Almirall Hermal GmbH Topische Zusammensetzung enthaltend einen Retinoid-Rezeptor-Agonist
FR2916966B1 (fr) * 2007-06-11 2011-01-14 Galderma Res & Dev Compositions comprenant au moins un compose retinoide, un compose anti-irritant et du peroxyde de benzoyle, et leurs utilisations
FR2916975B1 (fr) * 2007-06-11 2009-09-04 Galderma Res & Dev Compositions comprenant au moins un compose retinoide, un compose anti-irritant et du peroxyde de benzoyle, et leurs utilisations
EP2065032A1 (en) * 2007-11-27 2009-06-03 Galderma Research & Development A method for producing adapalene gels
CN105287484A (zh) * 2007-11-30 2016-02-03 盖尔德马研究及发展公司 含有萘甲酸衍生物、过氧化苯甲酰和成膜剂的组合物
ES2773931T3 (es) 2008-06-05 2020-07-15 Bausch Health Ireland Ltd Formulaciones farmacéuticas tópicas que contienen una baja concentración de peróxido de benzoílo en suspensión en agua y un solvente orgánico miscible en agua
KR20180023070A (ko) 2008-11-07 2018-03-06 클록스 테크놀로지스 인크. 히알루론산, 글루코사민 또는 알란토인을 포함하는 산화성의 광활성화된 피부 회춘용 조성물
US9682031B2 (en) 2009-10-07 2017-06-20 Tagra Biotechnologies Ltd. Microcapsules comprising benzoyl peroxide and topical compositions comprising them
CA2777489C (en) * 2009-10-21 2018-11-20 Dow Pharmaceutical Sciences, Inc. Method for wetting a powder containing benzoyl peroxide
BR112012019827A2 (pt) 2010-02-09 2016-05-17 Galderma Res & Dev utilização de uma combinação do adapaleno com o peróxido de benzoílo
FR2969492B1 (fr) * 2010-12-23 2013-07-05 Galderma Res & Dev Mousses dermatologiques obtenues a partir d'un gel ou d'une suspension contenant de l'adapalene
FR2969491B1 (fr) * 2010-12-23 2013-07-12 Galderma Res & Dev Mousses dermatologiques obtenues a partir d'un gel ou d'une suspension contenant une combinaison d'adapalene et de bpo
US8563535B2 (en) 2011-03-29 2013-10-22 Kamal Mehta Combination composition comprising benzoyl peroxide and adapalene
WO2013175011A1 (en) 2012-05-25 2013-11-28 Galderma Research & Development Treatment of preadolescent moderate acne vulgaris
DK2919747T3 (en) * 2012-11-13 2019-01-28 Galderma Sa BPO VASKEGELSAMMENSÆTNING
US9687465B2 (en) 2012-11-27 2017-06-27 Sol-Gel Technologies Ltd. Compositions for the treatment of rosacea
EP3082785A1 (en) 2013-12-19 2016-10-26 Galderma Research & Development Therapy regimen for treating severe acne related diseases
KR20160130862A (ko) 2014-04-01 2016-11-14 갈데르마 리써어치 앤드 디벨로프먼트 여드름 흉터의 치료를 위한 아다팔렌 및 벤조일 퍼옥시드의 조합
MX2017000717A (es) 2014-07-25 2017-05-01 Galderma Res & Dev Combinacion de adapaleno y peroxido de benzoilo para el tratamiento del acne grave.
JP6526322B2 (ja) * 2015-08-20 2019-06-05 ソル − ゲル テクノロジーズ リミテッド 過酸化ベンゾイルおよびアダパレンを含む局所投与用組成物
WO2018080284A1 (ko) * 2016-10-31 2018-05-03 (주)동구바이오제약 여드름 치료용 약물의 생체이용률을 증진시키는 약학적 조성물
CN106729722B (zh) * 2016-11-21 2020-05-12 成都山信药业有限公司 一种制备稳定复方制剂的方法及复方制剂
HUE073201T2 (hu) 2017-07-12 2026-01-28 Sol Gel Tech Ltd Kapszulázott tretinoint tartalmazó készítmények
JP2022527549A (ja) * 2019-04-04 2022-06-02 ガルデルマ ホールディング エスエー 炭酸イソプロピル過酸化ベンゾイル組成物及び使用の方法
WO2023112664A1 (ja) * 2021-12-14 2023-06-22 ロート製薬株式会社 過酸化ベンゾイルを含有する医薬外用組成物
WO2023177625A1 (en) * 2022-03-14 2023-09-21 Blue Hill Technologies Llc Shelf-stable formulations of benzoyl peroxide and methods of producing same

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378523A1 (fr) * 1977-01-26 1978-08-25 Grupper Charles Medicament pour le traitement de l'acne
US4189501A (en) * 1977-10-07 1980-02-19 A. H. C. Pharmacal, Inc. Composition and method for the treatment of acne
LU85849A1 (fr) * 1985-04-11 1986-11-05 Cird Derives benzonaphtaleniques,leur procede de preparation et leur application dans les domaines pharmaceutiques et cosmetiques
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation
FR2628319B1 (fr) * 1988-03-09 1990-12-07 Oreal Compositions pharmaceutiques et cosmetiques a base de peroxyde de benzoyle et de sels d'ammonium quaternaires
JP3555762B2 (ja) * 1991-10-16 2004-08-18 リチャードソン、ビックス、インコーポレーテッド 非イオン性ポリアクリルアミド誘導体を含有した低ｐＨ水性化粧品ゲル
US5470884A (en) * 1994-05-19 1995-11-28 Procter & Gamble Anti-acne compositions
FR2785284B1 (fr) * 1998-11-02 2000-12-01 Galderma Res & Dev Analogues de la vitamine d
FR2787322B1 (fr) * 1998-12-18 2002-10-18 Galderma Res & Dev Emulsion huile-dans-eau comprenant un agent actif micronise et un systeme emulsionnant approprie
WO2001045647A2 (de) * 1999-12-20 2001-06-28 Henkel Kommanditgesellschaft Auf Aktien Tablettierung verdickender systeme
FR2833841B1 (fr) * 2001-12-21 2005-07-22 Galderma Res & Dev Gel comprenant au moins un retinoide et du peroxyde de benzoyle

Also Published As

Publication number Publication date
BRPI0214264B8 (pt) 2021-05-25
EP1458369B1 (fr) 2006-12-06
WO2003055472A1 (fr) 2003-07-10
KR101014586B1 (ko) 2011-02-16
RU2004122429A (ru) 2005-03-20
HUP0500006A3 (en) 2009-09-28
AU2008246274A1 (en) 2008-12-11
AU2008246274B2 (en) 2011-05-19
RU2320327C2 (ru) 2008-03-27
ES2275948T3 (es) 2007-06-16
JP4889922B2 (ja) 2012-03-07
CY1107583T1 (el) 2013-03-13
JP2011037904A (ja) 2011-02-24
ZA200403759B (en) 2005-11-30
PT1458369E (pt) 2007-03-30
FR2833841B1 (fr) 2005-07-22
HUP0500006A2 (en) 2006-08-28
PL220838B1 (pl) 2016-01-29
CN1329025C (zh) 2007-08-01
MXPA04005918A (es) 2004-11-01
JP2005513146A (ja) 2005-05-12
DE60216634D1 (de) 2007-01-18
ATE347354T1 (de) 2006-12-15
FR08C0024I2 (enExample) 2009-11-20
DE122008000041I1 (de) 2008-11-20
AR038026A1 (es) 2004-12-22
AU2002364437A1 (en) 2003-07-15
KR20050016290A (ko) 2005-02-21
CA2466321C (fr) 2011-11-08
AU2002364437B2 (en) 2008-08-21
PL372270A1 (en) 2005-07-11
EP1458369A1 (fr) 2004-09-22
FR2833841A1 (fr) 2003-06-27
BR0214264A (pt) 2004-09-21
JP5478468B2 (ja) 2014-04-23
FR08C0024I1 (enExample) 2008-07-18
BRPI0214264B1 (pt) 2017-04-18
CN1607946A (zh) 2005-04-20
CA2466321A1 (fr) 2003-07-10
DK1458369T3 (da) 2007-04-10
HU230439B1 (hu) 2016-06-28
SI1458369T1 (sl) 2007-04-30

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R065 Request for grant of supplementary protection certificate validly filed

Free format text: PRODUCT NAME: ZUSAMMENSETZUNG UMFASSEND ADAPALEN UND BENZOYLPEROXID IN ALLEN UNTER DAS GRUNDPATENT FALLENDEN FORMEN.; AUTHORISATION NO/DATE: 67913.00.00 20080229; 40440 20071218

Spc suppl protection certif: 122008000041

Free format text: PRODUCT NAME: ADAPALEN IN KOMBINATION MIT BENZOYLPEROXID; AUTHORISATION NO/DATE: 67913.00.00 20080229; 40440 20071218

Spc suppl protection certif: 122008000041

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