CA2466321C - Gel comprenant au moins un retinoide et du peroxyde de benzoyle - Google Patents
Gel comprenant au moins un retinoide et du peroxyde de benzoyle Download PDFInfo
- Publication number
- CA2466321C CA2466321C CA2466321A CA2466321A CA2466321C CA 2466321 C CA2466321 C CA 2466321C CA 2466321 A CA2466321 A CA 2466321A CA 2466321 A CA2466321 A CA 2466321A CA 2466321 C CA2466321 C CA 2466321C
- Authority
- CA
- Canada
- Prior art keywords
- composition
- benzoyl peroxide
- composition according
- retinoid
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000004342 Benzoyl peroxide Substances 0.000 title claims abstract description 87
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 title claims abstract description 87
- 235000019400 benzoyl peroxide Nutrition 0.000 title claims abstract description 87
- 150000004492 retinoid derivatives Chemical class 0.000 title claims abstract description 42
- 239000000203 mixture Substances 0.000 claims abstract description 155
- 239000003349 gelling agent Substances 0.000 claims abstract description 32
- 238000000034 method Methods 0.000 claims abstract description 18
- 239000002537 cosmetic Substances 0.000 claims abstract description 12
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical group CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 94
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 64
- 238000002360 preparation method Methods 0.000 claims description 31
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 29
- 239000012071 phase Substances 0.000 claims description 25
- 238000011282 treatment Methods 0.000 claims description 24
- 238000003756 stirring Methods 0.000 claims description 23
- 206010000496 acne Diseases 0.000 claims description 20
- 239000007788 liquid Substances 0.000 claims description 20
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 20
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- LZCDAPDGXCYOEH-UHFFFAOYSA-N adapalene Chemical compound C1=C(C(O)=O)C=CC2=CC(C3=CC=C(C(=C3)C34CC5CC(CC(C5)C3)C4)OC)=CC=C21 LZCDAPDGXCYOEH-UHFFFAOYSA-N 0.000 claims description 16
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- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 7
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- APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical compound [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 claims description 6
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- ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 claims 2
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 11
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- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid group Chemical group C(C1=CC=CC=C1)(=O)O WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 7
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Toxicology (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0116747A FR2833841B1 (fr) | 2001-12-21 | 2001-12-21 | Gel comprenant au moins un retinoide et du peroxyde de benzoyle |
| FR0116747 | 2001-12-21 | ||
| PCT/FR2002/004233 WO2003055472A1 (fr) | 2001-12-21 | 2002-12-09 | Gel comprenant au moins un retinoide et du peroxyde de benzoyle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2466321A1 CA2466321A1 (fr) | 2003-07-10 |
| CA2466321C true CA2466321C (fr) | 2011-11-08 |
Family
ID=8870899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2466321A Expired - Fee Related CA2466321C (fr) | 2001-12-21 | 2002-12-09 | Gel comprenant au moins un retinoide et du peroxyde de benzoyle |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1458369B1 (enExample) |
| JP (2) | JP4889922B2 (enExample) |
| KR (1) | KR101014586B1 (enExample) |
| CN (1) | CN1329025C (enExample) |
| AR (1) | AR038026A1 (enExample) |
| AT (1) | ATE347354T1 (enExample) |
| AU (2) | AU2002364437B2 (enExample) |
| BR (1) | BRPI0214264B8 (enExample) |
| CA (1) | CA2466321C (enExample) |
| CY (1) | CY1107583T1 (enExample) |
| DE (2) | DE122008000041I1 (enExample) |
| DK (1) | DK1458369T3 (enExample) |
| ES (1) | ES2275948T3 (enExample) |
| FR (2) | FR2833841B1 (enExample) |
| HU (1) | HU230439B1 (enExample) |
| MX (1) | MXPA04005918A (enExample) |
| PL (1) | PL220838B1 (enExample) |
| PT (1) | PT1458369E (enExample) |
| RU (1) | RU2320327C2 (enExample) |
| SI (1) | SI1458369T1 (enExample) |
| WO (1) | WO2003055472A1 (enExample) |
| ZA (1) | ZA200403759B (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2833841B1 (fr) * | 2001-12-21 | 2005-07-22 | Galderma Res & Dev | Gel comprenant au moins un retinoide et du peroxyde de benzoyle |
| US7820186B2 (en) | 2001-12-21 | 2010-10-26 | Galderma Research & Development | Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt |
| EP1813312A3 (en) * | 2002-09-05 | 2010-03-24 | Galderma Research & Development | Depigmenting composition for the skin comprising adapalene and at least one depigmenting agent |
| US7544674B2 (en) | 2002-10-25 | 2009-06-09 | Galderma S.A. | Topical skin care composition |
| CA2586798A1 (en) * | 2004-11-09 | 2006-05-18 | Imaginative Research Associates, Inc. | Retinoid solutions and formulations made therefrom |
| EP1919606A2 (en) | 2005-08-02 | 2008-05-14 | Sol-Gel Technologies Ltd. | Metal oxide coating of water insoluble ingredients |
| FR2889662B1 (fr) * | 2005-08-11 | 2011-01-14 | Galderma Res & Dev | Emulsion de type huile-dans-eau pour application topique en dermatologie |
| FR2890314B1 (fr) * | 2005-09-02 | 2009-03-20 | Galderma Res & Dev | Compositiondepigmentante de la peau comprenant de l'adapalene au moins un agent depigmentant et au moins un agent anti-inflammatoire |
| CA2616915A1 (en) * | 2005-09-02 | 2007-05-10 | Isabelle Pelisson | Depigmenting composition for the skin, comprising adapalene, at least one depigmenting agent and at least one anti-inflammatory agent |
| KR101368107B1 (ko) * | 2006-03-31 | 2014-03-14 | 스티펠 리서치 오스트레일리아 피티와이 리미티드 | 발포성 현탁겔 |
| FR2901139B1 (fr) * | 2006-05-17 | 2009-03-20 | Galderma Res & Dev S N C Snc | Compositions comprenant au moins un derive de l'acide naphtoique et du peroxyde de benzoyle, leurs procedes de preparation, et leurs utilisations |
| US8080537B2 (en) | 2006-07-13 | 2011-12-20 | Galderma Research & Development | Combinations of adapalene and benzoyl peroxide for treating acne lesions |
| FR2903603B1 (fr) * | 2006-07-13 | 2009-03-20 | Galderma Res & Dev S N C Snc | Combinaison d'adapalene et de peroxyde de benzole dans le traitement de l'acne |
| CA2656451C (en) * | 2006-07-13 | 2015-01-27 | Galderma Research & Development | Composition comprising a retinoid and benzoyl peroxide |
| FR2903604B1 (fr) | 2006-07-13 | 2008-09-05 | Galderma Res & Dev S N C Snc | Composition comprenant un retinoide et du peroxyde de benzoyle |
| FR2909000B1 (fr) | 2006-11-28 | 2009-02-06 | Galderma Res & Dev S N C Snc | Compositions comprenant du peroxyde de benzoyle, au moins un derive de l'acide naphtoique et au moins un compose de type polymeres de polyurethane ou des derives de celui-ci, et leurs utilisations. |
| FR2910321B1 (fr) * | 2006-12-21 | 2009-07-10 | Galderma Res & Dev S N C Snc | Gel creme comprenant au moins un retinoide et du peroxyde de benzole |
| FR2910320B1 (fr) * | 2006-12-21 | 2009-02-13 | Galderma Res & Dev S N C Snc | Emulsion comprenant au moins un retinoide et du peroxyde de benzole |
| RU2481832C2 (ru) * | 2007-01-30 | 2013-05-20 | Галдерма Ресерч Энд Девелопмент | Применение адапалена и пероксида бензоила для продолжительного лечения угрей обыкновенных |
| CA2824842C (en) | 2007-02-01 | 2016-10-11 | Sol-Gel Technologies Ltd. | Method for preparing particles comprising metal oxide coating and particles with metal oxide coating |
| MX2009008250A (es) * | 2007-02-01 | 2009-08-27 | Sol Gel Technologies Ltd | Composiciones para aplicacion topica que comprenden un peroxido y retinoide. |
| EP1967180A1 (de) * | 2007-03-06 | 2008-09-10 | Almirall Hermal GmbH | Topische Zusammensetzung enthaltend einen Retinoid-Rezeptor-Agonist |
| FR2916966B1 (fr) * | 2007-06-11 | 2011-01-14 | Galderma Res & Dev | Compositions comprenant au moins un compose retinoide, un compose anti-irritant et du peroxyde de benzoyle, et leurs utilisations |
| FR2916975B1 (fr) * | 2007-06-11 | 2009-09-04 | Galderma Res & Dev | Compositions comprenant au moins un compose retinoide, un compose anti-irritant et du peroxyde de benzoyle, et leurs utilisations |
| EP2065032A1 (en) * | 2007-11-27 | 2009-06-03 | Galderma Research & Development | A method for producing adapalene gels |
| RU2526905C2 (ru) * | 2007-11-30 | 2014-08-27 | Галдерма Ресерч Энд Девелопмент | Композиции, включающие по меньшей мере одно производное нафтойной кислоты, бензоилпероксид и по меньшей мере один пленкообразующий компонент, способы их получения и их применения |
| PT2299810T (pt) | 2008-06-05 | 2020-03-04 | Bausch Health Ireland Ltd | Formulações tópicas farmacológicas que contêm uma baixa concentração de peróxido de benzoilo em suspensão em água e um solvente orgânico miscível em água |
| PL2365829T3 (pl) | 2008-11-07 | 2018-01-31 | Klox Tech Inc | Połączenie środka utleniającego i fotoaktywatora do gojenia ran |
| WO2011042902A2 (en) * | 2009-10-07 | 2011-04-14 | Tagra Biotechnologies Ltd | Microcapsules comprising benzoyl peroxide and topical compositions comprising them |
| BR112012009644A2 (pt) * | 2009-10-21 | 2015-09-29 | Dow Pharmaceutical Sciences | método para umedecer um pó contendo o peróxido de benzoíla |
| WO2011098391A1 (en) | 2010-02-09 | 2011-08-18 | Galderma Research & Development | A dermatological composition comprising a combination of adapalene and benzoyl peroxide for the treatment of acne in non- caucasian population with decrease of post- inflammatory hyperpigmentation |
| FR2969492B1 (fr) * | 2010-12-23 | 2013-07-05 | Galderma Res & Dev | Mousses dermatologiques obtenues a partir d'un gel ou d'une suspension contenant de l'adapalene |
| FR2969491B1 (fr) * | 2010-12-23 | 2013-07-12 | Galderma Res & Dev | Mousses dermatologiques obtenues a partir d'un gel ou d'une suspension contenant une combinaison d'adapalene et de bpo |
| US8563535B2 (en) | 2011-03-29 | 2013-10-22 | Kamal Mehta | Combination composition comprising benzoyl peroxide and adapalene |
| EP2854791A1 (en) | 2012-05-25 | 2015-04-08 | Galderma Research & Development | Treatment of preadolescent moderate acne vulgaris |
| BR112015010819B1 (pt) * | 2012-11-13 | 2019-12-17 | Galderma Sa | composição de lavagem tópica e uso da composição |
| US9687465B2 (en) | 2012-11-27 | 2017-06-27 | Sol-Gel Technologies Ltd. | Compositions for the treatment of rosacea |
| JP2017500328A (ja) | 2013-12-19 | 2017-01-05 | ガルデルマ・リサーチ・アンド・デヴェロップメント | 重度のざ瘡に関連した疾患を処置する治療レジメン |
| WO2015150332A1 (en) | 2014-04-01 | 2015-10-08 | Galderma Research & Development | Combination of adapalene and benzoyl peroxide for treating acne scars |
| DK3171857T3 (da) | 2014-07-25 | 2020-09-21 | Galderma Res & Dev | Kombination af adapalen og benzoylperoxid til behandling af alvorlig acne |
| JP6526322B2 (ja) * | 2015-08-20 | 2019-06-05 | ソル − ゲル テクノロジーズ リミテッド | 過酸化ベンゾイルおよびアダパレンを含む局所投与用組成物 |
| WO2018080284A1 (ko) * | 2016-10-31 | 2018-05-03 | (주)동구바이오제약 | 여드름 치료용 약물의 생체이용률을 증진시키는 약학적 조성물 |
| CN106729722B (zh) * | 2016-11-21 | 2020-05-12 | 成都山信药业有限公司 | 一种制备稳定复方制剂的方法及复方制剂 |
| PL3651756T3 (pl) | 2017-07-12 | 2025-11-03 | Sol-Gel Technologies Ltd. | Kompozycje zawierające kapsułkowaną tretinoinę |
| JP2022527549A (ja) * | 2019-04-04 | 2022-06-02 | ガルデルマ ホールディング エスエー | 炭酸イソプロピル過酸化ベンゾイル組成物及び使用の方法 |
| WO2023112664A1 (ja) * | 2021-12-14 | 2023-06-22 | ロート製薬株式会社 | 過酸化ベンゾイルを含有する医薬外用組成物 |
| EP4493179A1 (en) * | 2022-03-14 | 2025-01-22 | Blue Hill Technologies LLC | Shelf-stable formulations of benzoyl peroxide and methods of producing same |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2378523A1 (fr) * | 1977-01-26 | 1978-08-25 | Grupper Charles | Medicament pour le traitement de l'acne |
| US4189501A (en) * | 1977-10-07 | 1980-02-19 | A. H. C. Pharmacal, Inc. | Composition and method for the treatment of acne |
| LU85849A1 (fr) * | 1985-04-11 | 1986-11-05 | Cird | Derives benzonaphtaleniques,leur procede de preparation et leur application dans les domaines pharmaceutiques et cosmetiques |
| US4792452A (en) * | 1987-07-28 | 1988-12-20 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| FR2628319B1 (fr) * | 1988-03-09 | 1990-12-07 | Oreal | Compositions pharmaceutiques et cosmetiques a base de peroxyde de benzoyle et de sels d'ammonium quaternaires |
| MA22677A1 (fr) * | 1991-10-16 | 1993-07-01 | Richardson Vicks Inc | Compositions cosmetiques en gels |
| US5470884A (en) * | 1994-05-19 | 1995-11-28 | Procter & Gamble | Anti-acne compositions |
| FR2785284B1 (fr) * | 1998-11-02 | 2000-12-01 | Galderma Res & Dev | Analogues de la vitamine d |
| FR2787322B1 (fr) * | 1998-12-18 | 2002-10-18 | Galderma Res & Dev | Emulsion huile-dans-eau comprenant un agent actif micronise et un systeme emulsionnant approprie |
| WO2001045647A2 (de) * | 1999-12-20 | 2001-06-28 | Henkel Kommanditgesellschaft Auf Aktien | Tablettierung verdickender systeme |
| FR2833841B1 (fr) * | 2001-12-21 | 2005-07-22 | Galderma Res & Dev | Gel comprenant au moins un retinoide et du peroxyde de benzoyle |
-
2001
- 2001-12-21 FR FR0116747A patent/FR2833841B1/fr not_active Expired - Fee Related
-
2002
- 2002-12-09 CN CNB028258460A patent/CN1329025C/zh not_active Expired - Lifetime
- 2002-12-09 BR BRPI0214264A patent/BRPI0214264B8/pt not_active IP Right Cessation
- 2002-12-09 KR KR1020047008461A patent/KR101014586B1/ko not_active Expired - Lifetime
- 2002-12-09 MX MXPA04005918A patent/MXPA04005918A/es active IP Right Grant
- 2002-12-09 DE DE122008000041C patent/DE122008000041I1/de active Pending
- 2002-12-09 PT PT02799797T patent/PT1458369E/pt unknown
- 2002-12-09 AT AT02799797T patent/ATE347354T1/de active
- 2002-12-09 EP EP02799797A patent/EP1458369B1/fr not_active Expired - Lifetime
- 2002-12-09 HU HU0500006A patent/HU230439B1/hu unknown
- 2002-12-09 SI SI200230454T patent/SI1458369T1/sl unknown
- 2002-12-09 CA CA2466321A patent/CA2466321C/fr not_active Expired - Fee Related
- 2002-12-09 WO PCT/FR2002/004233 patent/WO2003055472A1/fr not_active Ceased
- 2002-12-09 AU AU2002364437A patent/AU2002364437B2/en not_active Expired
- 2002-12-09 DE DE60216634T patent/DE60216634T2/de not_active Expired - Lifetime
- 2002-12-09 ES ES02799797T patent/ES2275948T3/es not_active Expired - Lifetime
- 2002-12-09 JP JP2003556050A patent/JP4889922B2/ja not_active Expired - Lifetime
- 2002-12-09 PL PL372270A patent/PL220838B1/pl unknown
- 2002-12-09 DK DK02799797T patent/DK1458369T3/da active
- 2002-12-09 RU RU2004122429/15A patent/RU2320327C2/ru active
- 2002-12-18 AR ARP020104930A patent/AR038026A1/es not_active Application Discontinuation
-
2004
- 2004-05-17 ZA ZA2004/03759A patent/ZA200403759B/en unknown
-
2007
- 2007-01-29 CY CY20071100120T patent/CY1107583T1/el unknown
-
2008
- 2008-06-05 FR FR08C0024C patent/FR08C0024I2/fr active Active
- 2008-11-21 AU AU2008246274A patent/AU2008246274B2/en not_active Expired
-
2010
- 2010-11-26 JP JP2010264093A patent/JP5478468B2/ja not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2466321C (fr) | Gel comprenant au moins un retinoide et du peroxyde de benzoyle | |
| EP3025763B1 (fr) | Gel creme comprenant au moins un retinoide et du peroxyde de benzoyle | |
| US8241649B2 (en) | Dermatological/cosmetic gels comprising at least one retinoid and/or retinoid salt and benzoyl peroxide | |
| EP2125117B1 (fr) | Emulsion comprenant au moins un retinoide et du péroxyde de benzoyle | |
| CA2617963A1 (fr) | Emulsion de type huile-dans-eau pour application topique en dermatologie | |
| EP2240152B1 (fr) | Composition comprenant un retinoide et du peroxyde de benzoyle disperse | |
| FR2903604A1 (fr) | Composition comprenant un retinoide et du peroxyde de benzoyle |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20201209 |