DE602008004259D1 - Neues einstufiges verfahren zur herstellung von vernetzten poly(allylamin)-polymeren - Google Patents
Neues einstufiges verfahren zur herstellung von vernetzten poly(allylamin)-polymerenInfo
- Publication number
- DE602008004259D1 DE602008004259D1 DE602008004259T DE602008004259T DE602008004259D1 DE 602008004259 D1 DE602008004259 D1 DE 602008004259D1 DE 602008004259 T DE602008004259 T DE 602008004259T DE 602008004259 T DE602008004259 T DE 602008004259T DE 602008004259 D1 DE602008004259 D1 DE 602008004259D1
- Authority
- DE
- Germany
- Prior art keywords
- polymers
- allylamine
- preparing
- universal process
- new universal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 229920000642 polymer Polymers 0.000 title abstract 4
- 229920000083 poly(allylamine) Polymers 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- -1 poly(allylamine) Polymers 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003431 cross linking reagent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/18—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with hydroxy groups and at least two amino groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
- C08F226/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
- C08F226/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
- C08F226/04—Diallylamine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polymerisation Methods In General (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07112604A EP2016947A1 (en) | 2007-07-17 | 2007-07-17 | Novel one step process for preparing cross-linked poly(allylamine) polymers |
| PCT/EP2008/059303 WO2009010531A1 (en) | 2007-07-17 | 2008-07-16 | Novel one step process for preparing cross-linked poly(allylamine) polymers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602008004259D1 true DE602008004259D1 (de) | 2011-02-10 |
Family
ID=38921775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602008004259T Active DE602008004259D1 (de) | 2007-07-17 | 2008-07-16 | Neues einstufiges verfahren zur herstellung von vernetzten poly(allylamin)-polymeren |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8394416B2 (https=) |
| EP (2) | EP2016947A1 (https=) |
| JP (1) | JP2010533758A (https=) |
| KR (1) | KR20100051616A (https=) |
| CN (1) | CN101743012B (https=) |
| AT (1) | ATE493136T1 (https=) |
| BR (1) | BRPI0813829A2 (https=) |
| CA (1) | CA2697130A1 (https=) |
| DE (1) | DE602008004259D1 (https=) |
| DK (1) | DK2175866T3 (https=) |
| ES (1) | ES2358381T3 (https=) |
| HR (1) | HRP20110181T1 (https=) |
| PL (1) | PL2175866T3 (https=) |
| PT (1) | PT2175866E (https=) |
| SI (1) | SI2175866T1 (https=) |
| WO (1) | WO2009010531A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8404784B2 (en) * | 2008-12-03 | 2013-03-26 | Navinta Llc | Manufacturing process of making polymeric amine salts |
| EP2443157A1 (en) * | 2009-06-16 | 2012-04-25 | Watson Pharma Private Limited | Processes for the preparation of sevelamer carbonate |
| IT1404163B1 (it) | 2011-02-01 | 2013-11-15 | Chemi Spa | Processo per la preparazione di poliallilamine reticolate o loro sali farmaceuticamente accettabili |
| CN102796259B (zh) * | 2011-05-24 | 2014-11-12 | 北大方正集团有限公司 | 碳酸司维拉姆的制备方法 |
| CN102796262B (zh) * | 2011-05-24 | 2014-11-12 | 北大方正集团有限公司 | 一种碳酸司维拉姆的制备方法 |
| CN103012789B (zh) * | 2011-09-23 | 2015-02-25 | 北大方正集团有限公司 | 烟酸司维拉姆的制备方法 |
| CN102675510B (zh) * | 2012-05-28 | 2014-04-02 | 诚达药业股份有限公司 | 司维拉姆的合成工艺 |
| CN102942646B (zh) * | 2012-10-26 | 2016-06-29 | 青岛正大海尔制药有限公司 | 一种高分子聚合物的合成与分离纯化方法 |
| EP3003327B1 (en) * | 2013-06-05 | 2017-08-09 | Tricida Inc. | Proton-binding polymers for oral administration |
| CN104448139B (zh) * | 2014-11-21 | 2016-08-17 | 新发药业有限公司 | 一种盐酸考来维仑的制备方法 |
| RS61409B1 (sr) | 2014-12-10 | 2021-03-31 | Tricida Inc | Polimeri koji vezuju protone za oralnu primenu opis |
| MA41202A (fr) * | 2014-12-18 | 2017-10-24 | Genzyme Corp | Copolymères polydiallymine réticulé pour le traitement du diabète de type 2 |
| CN109414453B (zh) | 2016-05-06 | 2023-02-17 | 特里赛达公司 | 用于治疗酸碱失衡的组合物 |
| CN106008813B (zh) * | 2016-06-15 | 2017-11-14 | 新发药业有限公司 | 溶液聚合制备盐酸考来维仑的方法 |
| KR101853260B1 (ko) * | 2016-11-29 | 2018-06-14 | 주식회사 퍼슨 | 세벨라머 카보네이트의 제조방법 |
| EP3564292B1 (en) | 2016-12-28 | 2021-06-16 | FUJIFILM Corporation | Emulsion of nitrogen atom-containing polymer or salt thereof, production method therefor, and production method for particles |
| JP7057902B2 (ja) * | 2017-07-05 | 2022-04-21 | 日東紡績株式会社 | 高純度アリルアミン（共）重合体及びその製造方法 |
| US10934380B1 (en) | 2017-09-25 | 2021-03-02 | Tricida, Inc. | Crosslinked poly(allylamine) polymer pharmaceutical compositions |
| CN111225674A (zh) | 2017-10-16 | 2020-06-02 | 富士胶片株式会社 | 高磷血症治疗剂 |
| CA3080651A1 (en) | 2017-11-03 | 2019-05-09 | Tricida, Inc. | Compositions for and method of treating acid-base disorders |
| CN108751208B (zh) * | 2018-06-05 | 2020-06-30 | 山东师范大学 | 一种无表面活性剂微乳液制备的单分散二氧化硅纳米球及其制备方法 |
| EP4164659B1 (en) | 2021-08-24 | 2024-03-27 | Waterstone Pharmaceuticals (Wuhan) Co., Ltd. | Polymers, compositions and methods for treating hyperuricemia |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE757856A (fr) * | 1969-10-27 | 1971-04-22 | Michelin & Cie | Perfectionnements aux polyurethanes vulcanisables au soufre |
| JPS6090243A (ja) | 1983-10-25 | 1985-05-21 | Nitto Boseki Co Ltd | 小球状モノアリルアミン橋かけ重合体の製造方法 |
| JP2862933B2 (ja) * | 1990-02-06 | 1999-03-03 | 東芝シリコーン株式会社 | Ｎ―アルケニル―ｎ―グリシジル（メタ）アクリルアミド化合物の製造方法 |
| JP2967952B2 (ja) * | 1991-07-23 | 1999-10-25 | 日本化薬株式会社 | 多孔性ポリマーの製造方法 |
| US5496545A (en) | 1993-08-11 | 1996-03-05 | Geltex Pharmaceuticals, Inc. | Phosphate-binding polymers for oral administration |
| US5667775A (en) | 1993-08-11 | 1997-09-16 | Geltex Pharmaceuticals, Inc. | Phosphate-binding polymers for oral administration |
| US5414068A (en) * | 1994-01-24 | 1995-05-09 | Rohm And Haas Company | Crosslinked anion exchange particles and method for producing the particles |
| TW474813B (en) | 1994-06-10 | 2002-02-01 | Geltex Pharma Inc | Alkylated composition for removing bile salts from a patient |
| JP3952223B2 (ja) * | 1997-05-28 | 2007-08-01 | 日東紡績株式会社 | アリルアミン重合体 |
| JP3363143B2 (ja) * | 1998-10-12 | 2003-01-08 | 中外製薬株式会社 | リン酸結合性ポリマー粒子 |
| TW568788B (en) * | 1998-10-12 | 2004-01-01 | Chugai Pharmaceutical Co Ltd | Polymer combining with phosphoric acid and preparation containing the same |
| US6362266B1 (en) | 1999-09-03 | 2002-03-26 | The Dow Chemical Company | Process for reducing cohesiveness of polyallylamine polymer gels during drying |
| US6733780B1 (en) | 1999-10-19 | 2004-05-11 | Genzyme Corporation | Direct compression polymer tablet core |
| GB2374072B (en) * | 2000-06-16 | 2004-09-22 | Nippon Catalytic Chem Ind | Crosslinked polymer method for manufacturing it and use thereof |
| DE60212819T2 (de) | 2001-04-18 | 2006-11-23 | Genzyme Corp., Cambridge | Salzformarme polyallylamine |
| US7459502B2 (en) * | 2003-11-03 | 2008-12-02 | Ilypsa, Inc. | Pharmaceutical compositions comprising crosslinked polyamine polymers |
| US7985418B2 (en) | 2004-11-01 | 2011-07-26 | Genzyme Corporation | Aliphatic amine polymer salts for tableting |
| HUE026628T2 (en) | 2005-09-15 | 2016-06-28 | Genzyme Corp | Pouches for amine polymers |
-
2007
- 2007-07-17 EP EP07112604A patent/EP2016947A1/en not_active Withdrawn
-
2008
- 2008-07-16 BR BRPI0813829-0A2A patent/BRPI0813829A2/pt not_active IP Right Cessation
- 2008-07-16 KR KR1020107001256A patent/KR20100051616A/ko not_active Ceased
- 2008-07-16 PL PL08775124T patent/PL2175866T3/pl unknown
- 2008-07-16 US US12/668,758 patent/US8394416B2/en not_active Expired - Fee Related
- 2008-07-16 HR HR20110181T patent/HRP20110181T1/hr unknown
- 2008-07-16 CN CN2008800248423A patent/CN101743012B/zh not_active Expired - Fee Related
- 2008-07-16 JP JP2010516501A patent/JP2010533758A/ja active Pending
- 2008-07-16 AT AT08775124T patent/ATE493136T1/de active
- 2008-07-16 CA CA2697130A patent/CA2697130A1/en not_active Abandoned
- 2008-07-16 EP EP08775124A patent/EP2175866B1/en not_active Not-in-force
- 2008-07-16 PT PT08775124T patent/PT2175866E/pt unknown
- 2008-07-16 WO PCT/EP2008/059303 patent/WO2009010531A1/en not_active Ceased
- 2008-07-16 ES ES08775124T patent/ES2358381T3/es active Active
- 2008-07-16 SI SI200830184T patent/SI2175866T1/sl unknown
- 2008-07-16 DK DK08775124.4T patent/DK2175866T3/da active
- 2008-07-16 DE DE602008004259T patent/DE602008004259D1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| HK1140945A1 (en) | 2010-10-29 |
| CN101743012B (zh) | 2012-07-04 |
| PT2175866E (pt) | 2011-04-01 |
| JP2010533758A (ja) | 2010-10-28 |
| KR20100051616A (ko) | 2010-05-17 |
| US8394416B2 (en) | 2013-03-12 |
| PL2175866T3 (pl) | 2011-05-31 |
| DK2175866T3 (da) | 2011-04-04 |
| US20100183732A1 (en) | 2010-07-22 |
| BRPI0813829A2 (pt) | 2015-01-06 |
| ATE493136T1 (de) | 2011-01-15 |
| CN101743012A (zh) | 2010-06-16 |
| ES2358381T3 (es) | 2011-05-10 |
| SI2175866T1 (sl) | 2011-04-29 |
| EP2016947A1 (en) | 2009-01-21 |
| EP2175866B1 (en) | 2010-12-29 |
| EP2175866A1 (en) | 2010-04-21 |
| CA2697130A1 (en) | 2009-01-22 |
| WO2009010531A1 (en) | 2009-01-22 |
| HRP20110181T1 (hr) | 2011-04-30 |
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