ATE493136T1 - Neues einstufiges verfahren zur herstellung von vernetzten poly(allylamin)-polymeren - Google Patents

Neues einstufiges verfahren zur herstellung von vernetzten poly(allylamin)-polymeren

Info

Publication number
ATE493136T1
ATE493136T1 AT08775124T AT08775124T ATE493136T1 AT E493136 T1 ATE493136 T1 AT E493136T1 AT 08775124 T AT08775124 T AT 08775124T AT 08775124 T AT08775124 T AT 08775124T AT E493136 T1 ATE493136 T1 AT E493136T1
Authority
AT
Austria
Prior art keywords
polymers
linked poly
step process
allylamin
new
Prior art date
Application number
AT08775124T
Other languages
English (en)
Inventor
Sabrina Bianchi
Valter Castelvetro
Giovanni Marras
Sonja Bellomi
Graziano Castaldi
Gianpiero Ventimiglia
Original Assignee
Chemo Iberica Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Iberica Sa filed Critical Chemo Iberica Sa
Application granted granted Critical
Publication of ATE493136T1 publication Critical patent/ATE493136T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/18Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with hydroxy groups and at least two amino groups bound to the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/02Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/02Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • C08F226/04Diallylamine
AT08775124T 2007-07-17 2008-07-16 Neues einstufiges verfahren zur herstellung von vernetzten poly(allylamin)-polymeren ATE493136T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07112604A EP2016947A1 (de) 2007-07-17 2007-07-17 Neuartiges Verfahren zur Herstellung vernetzter Poly(allylamin-)Polymere in einem einzigen Schritt
PCT/EP2008/059303 WO2009010531A1 (en) 2007-07-17 2008-07-16 Novel one step process for preparing cross-linked poly(allylamine) polymers

Publications (1)

Publication Number Publication Date
ATE493136T1 true ATE493136T1 (de) 2011-01-15

Family

ID=38921775

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08775124T ATE493136T1 (de) 2007-07-17 2008-07-16 Neues einstufiges verfahren zur herstellung von vernetzten poly(allylamin)-polymeren

Country Status (17)

Country Link
US (1) US8394416B2 (de)
EP (2) EP2016947A1 (de)
JP (1) JP2010533758A (de)
KR (1) KR20100051616A (de)
CN (1) CN101743012B (de)
AT (1) ATE493136T1 (de)
BR (1) BRPI0813829A2 (de)
CA (1) CA2697130A1 (de)
DE (1) DE602008004259D1 (de)
DK (1) DK2175866T3 (de)
ES (1) ES2358381T3 (de)
HK (1) HK1140945A1 (de)
HR (1) HRP20110181T1 (de)
PL (1) PL2175866T3 (de)
PT (1) PT2175866E (de)
SI (1) SI2175866T1 (de)
WO (1) WO2009010531A1 (de)

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US8404784B2 (en) 2008-12-03 2013-03-26 Navinta Llc Manufacturing process of making polymeric amine salts
BRPI1012076A2 (pt) * 2009-06-16 2019-04-16 Watson Pharma Private Ltd processos para preparação de carbonato de sevelamer
IT1404163B1 (it) 2011-02-01 2013-11-15 Chemi Spa Processo per la preparazione di poliallilamine reticolate o loro sali farmaceuticamente accettabili
CN102796259B (zh) * 2011-05-24 2014-11-12 北大方正集团有限公司 碳酸司维拉姆的制备方法
CN102796262B (zh) * 2011-05-24 2014-11-12 北大方正集团有限公司 一种碳酸司维拉姆的制备方法
CN103012789B (zh) * 2011-09-23 2015-02-25 北大方正集团有限公司 烟酸司维拉姆的制备方法
CN102675510B (zh) * 2012-05-28 2014-04-02 诚达药业股份有限公司 司维拉姆的合成工艺
CN102942646B (zh) * 2012-10-26 2016-06-29 青岛正大海尔制药有限公司 一种高分子聚合物的合成与分离纯化方法
DK3287133T3 (da) 2013-06-05 2019-07-01 Tricida Inc Proton-bindende polymerer til oral indgivelse
CN104448139B (zh) * 2014-11-21 2016-08-17 新发药业有限公司 一种盐酸考来维仑的制备方法
PT3593808T (pt) 2014-12-10 2021-02-11 Tricida Inc Polímeros de ligação a protões para administração oral
MA41202A (fr) * 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
EP3452028A4 (de) * 2016-05-06 2020-04-15 Tricida Inc. Zusammensetzungen und verfahren zur behandlung von säure-basen-störungen
CN106008813B (zh) * 2016-06-15 2017-11-14 新发药业有限公司 溶液聚合制备盐酸考来维仑的方法
KR101853260B1 (ko) * 2016-11-29 2018-06-14 주식회사 퍼슨 세벨라머 카보네이트의 제조방법
CN110114389B (zh) 2016-12-28 2022-04-01 富士胶片株式会社 含氮原子的聚合物或其盐的乳化液、其制造方法、及粒子的制造方法
CN110831984B (zh) * 2017-07-05 2023-06-06 日东纺绩株式会社 高纯度烯丙胺(共)聚合物及其制造方法
US10934380B1 (en) 2017-09-25 2021-03-02 Tricida, Inc. Crosslinked poly(allylamine) polymer pharmaceutical compositions
CN111225674A (zh) 2017-10-16 2020-06-02 富士胶片株式会社 高磷血症治疗剂
WO2019090176A1 (en) * 2017-11-03 2019-05-09 Tricida, Inc. Compositions for and method of treating acid-base disorders
CN108751208B (zh) * 2018-06-05 2020-06-30 山东师范大学 一种无表面活性剂微乳液制备的单分散二氧化硅纳米球及其制备方法

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JPS6090243A (ja) 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
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JP2967952B2 (ja) * 1991-07-23 1999-10-25 日本化薬株式会社 多孔性ポリマーの製造方法
US5496545A (en) 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5667775A (en) 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5414068A (en) * 1994-01-24 1995-05-09 Rohm And Haas Company Crosslinked anion exchange particles and method for producing the particles
TW474813B (en) 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
JP3952223B2 (ja) * 1997-05-28 2007-08-01 日東紡績株式会社 アリルアミン重合体
TW568788B (en) * 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
JP3363143B2 (ja) * 1998-10-12 2003-01-08 中外製薬株式会社 リン酸結合性ポリマー粒子
US6362266B1 (en) 1999-09-03 2002-03-26 The Dow Chemical Company Process for reducing cohesiveness of polyallylamine polymer gels during drying
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US6646083B2 (en) * 2000-06-16 2003-11-11 Nippon Shokubai Co., Ltd. Crosslinked polymers containing tertiary amine and/or quaternary ammonium salt structures, processes for making and uses thereof
AU2002252632B2 (en) 2001-04-18 2004-09-23 Genzyme Corporation Low salt forms of polyallylamine
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
PT1924246E (pt) 2005-09-15 2016-02-10 Genzyme Corp Formulação sachê para polímeros com funcionalidade amina

Also Published As

Publication number Publication date
SI2175866T1 (sl) 2011-04-29
PT2175866E (pt) 2011-04-01
US20100183732A1 (en) 2010-07-22
PL2175866T3 (pl) 2011-05-31
KR20100051616A (ko) 2010-05-17
CA2697130A1 (en) 2009-01-22
EP2016947A1 (de) 2009-01-21
HK1140945A1 (en) 2010-10-29
DK2175866T3 (da) 2011-04-04
CN101743012B (zh) 2012-07-04
EP2175866A1 (de) 2010-04-21
ES2358381T3 (es) 2011-05-10
BRPI0813829A2 (pt) 2015-01-06
CN101743012A (zh) 2010-06-16
EP2175866B1 (de) 2010-12-29
HRP20110181T1 (hr) 2011-04-30
WO2009010531A1 (en) 2009-01-22
DE602008004259D1 (de) 2011-02-10
US8394416B2 (en) 2013-03-12
JP2010533758A (ja) 2010-10-28

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