DE602005013382D1 - Feste formen des magnesiumsalzes von (s)-omeprazol und verfahren zu deren herstellung - Google Patents

Feste formen des magnesiumsalzes von (s)-omeprazol und verfahren zu deren herstellung

Info

Publication number
DE602005013382D1
DE602005013382D1 DE602005013382T DE602005013382T DE602005013382D1 DE 602005013382 D1 DE602005013382 D1 DE 602005013382D1 DE 602005013382 T DE602005013382 T DE 602005013382T DE 602005013382 T DE602005013382 T DE 602005013382T DE 602005013382 D1 DE602005013382 D1 DE 602005013382D1
Authority
DE
Germany
Prior art keywords
magnesium salt
omeprazole
solid forms
solvent
omeprazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005013382T
Other languages
German (de)
English (en)
Inventor
Maimo Ramon Berenguer
Laura Coppi
Guillen Yolanda Gasanz
Ruperez Jorge Medrano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Quimica SA
Original Assignee
Esteve Quimica SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Quimica SA filed Critical Esteve Quimica SA
Publication of DE602005013382D1 publication Critical patent/DE602005013382D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE602005013382T 2004-07-02 2005-06-29 Feste formen des magnesiumsalzes von (s)-omeprazol und verfahren zu deren herstellung Expired - Lifetime DE602005013382D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200401729A ES2246149B1 (es) 2004-07-02 2004-07-02 Formas solidas de la sal magnesica de s-omeprazol y procedimientos para su preparacion.
PCT/EP2005/053062 WO2006003163A1 (en) 2004-07-02 2005-06-29 Solid forms of the magnesium salt of (s)-omeprazole and processes for their preparation

Publications (1)

Publication Number Publication Date
DE602005013382D1 true DE602005013382D1 (de) 2009-04-30

Family

ID=34972307

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005013382T Expired - Lifetime DE602005013382D1 (de) 2004-07-02 2005-06-29 Feste formen des magnesiumsalzes von (s)-omeprazol und verfahren zu deren herstellung

Country Status (19)

Country Link
US (1) US7902370B2 (forum.php)
EP (1) EP1765807B1 (forum.php)
JP (2) JP5575366B2 (forum.php)
KR (1) KR101290035B1 (forum.php)
CN (1) CN1976923B (forum.php)
AT (1) ATE425975T1 (forum.php)
AU (1) AU2005259205B2 (forum.php)
CA (1) CA2570559C (forum.php)
CY (1) CY1109048T1 (forum.php)
DE (1) DE602005013382D1 (forum.php)
DK (1) DK1765807T3 (forum.php)
ES (2) ES2246149B1 (forum.php)
HR (1) HRP20090211T1 (forum.php)
MX (1) MXPA06014736A (forum.php)
NO (1) NO20070635L (forum.php)
NZ (1) NZ552458A (forum.php)
PT (1) PT1765807E (forum.php)
WO (1) WO2006003163A1 (forum.php)
ZA (1) ZA200700865B (forum.php)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2246149B1 (es) * 2004-07-02 2007-06-01 Esteve Quimica, S.A. Formas solidas de la sal magnesica de s-omeprazol y procedimientos para su preparacion.
FR2920428B1 (fr) * 2007-08-29 2012-06-15 Univ Rouen Procede de dedoublement de sels de l'omeprazole
EP2147918A1 (en) 2008-07-21 2010-01-27 LEK Pharmaceuticals D.D. Process for the preparation of S-omeprazole magnesium in a stable form
CN103044400A (zh) * 2012-12-21 2013-04-17 北京华禧联合科技发展有限公司 埃索美拉唑镁盐及其制备方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
JP3350054B2 (ja) * 1994-07-08 2002-11-25 アストラゼネカ・アクチエボラーグ 複数単位の錠剤化された剤形▲ｉ▼
SE508669C2 (sv) 1996-04-26 1998-10-26 Astra Ab Nytt förfarande
SE510666C2 (sv) * 1996-12-20 1999-06-14 Astra Ab Nya Kristallmodifikationer
SE510650C2 (sv) 1997-05-30 1999-06-14 Astra Ab Ny förening
CN1636564A (zh) * 1999-08-26 2005-07-13 艾伊法马公司 含烷氧基取代苯并咪唑化合物的组合物和药物制剂及其制法
US6312712B1 (en) * 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6326384B1 (en) * 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
CA2409258A1 (en) 2000-05-15 2001-11-22 Ranbaxy Laboratories Limited Novel amorphous form of omeprazole salts
CA2386716C (en) * 2002-05-17 2012-07-24 Bernard Charles Sherman Magnesium salt of s-omeprazole
US7271182B2 (en) * 2000-08-04 2007-09-18 Takeda Pharmaceutical Company Limited Salts of benzimidazole compound and use thereof
SI20875A (sl) * 2001-04-25 2002-10-31 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristalna oblika omeprazola
WO2003089408A2 (en) * 2002-04-22 2003-10-30 Sun Pharmaceutical Industries Limited Optically active substituted pyridinylmethyl-sulphinyl-benzimidazole and salts
US6894066B2 (en) * 2002-05-09 2005-05-17 Bernard Charles Sherman Magnesium salt of S-omeprazole
AU2003262992A1 (en) * 2002-08-30 2004-03-19 Reddy's Laboratories Limited Amorphous hydrates of esomeprazole magnesium and process for the preparation thereof
CN1728997A (zh) * 2002-10-22 2006-02-01 兰贝克赛实验室有限公司 (es)奥美拉唑的无定形盐
WO2004046134A2 (en) * 2002-11-18 2004-06-03 Dr. Reddy's Laboratories Limited Crystalline form ii of esomeprazole magnesium trihydrate and process for its preparation
WO2004089935A1 (en) * 2003-04-10 2004-10-21 Hetero Drugs Limitd Novel crystalline forms of s-omeprazole magnesium
ES2246149B1 (es) * 2004-07-02 2007-06-01 Esteve Quimica, S.A. Formas solidas de la sal magnesica de s-omeprazol y procedimientos para su preparacion.

Also Published As

Publication number Publication date
MXPA06014736A (es) 2007-06-25
KR20070031992A (ko) 2007-03-20
US7902370B2 (en) 2011-03-08
CN1976923B (zh) 2011-08-24
ZA200700865B (en) 2009-09-30
EP1765807A1 (en) 2007-03-28
CA2570559A1 (en) 2006-01-12
EP1765807B1 (en) 2009-03-18
ES2246149B1 (es) 2007-06-01
AU2005259205B2 (en) 2011-01-27
CN1976923A (zh) 2007-06-06
ATE425975T1 (de) 2009-04-15
JP2008505160A (ja) 2008-02-21
CA2570559C (en) 2012-08-28
AU2005259205A1 (en) 2006-01-12
KR101290035B1 (ko) 2013-07-30
CY1109048T1 (forum.php) 2014-07-02
WO2006003163A1 (en) 2006-01-12
DK1765807T3 (da) 2009-06-08
NZ552458A (en) 2010-07-30
NO20070635L (no) 2007-03-20
US20070249684A1 (en) 2007-10-25
JP2014169302A (ja) 2014-09-18
PT1765807E (pt) 2009-04-13
ES2246149A1 (es) 2006-02-01
JP5575366B2 (ja) 2014-08-20
HRP20090211T1 (en) 2009-05-31
ES2323319T3 (es) 2009-07-13

Similar Documents

Publication Publication Date Title
BR9407655A (pt) Método para a produçao de steres cíclicos T
DE69909279D1 (de) Transxanthophyllesterkonzenrate von erhöhter reinheit und verfahren zu deren herstellung
Chavan et al. Efficient and mild method for preparation of allylic amines from aziridine-2-alcohols using PPh3/I2/imidazole
DE69426880T2 (de) Verfahren zur herstellung von aminosäureester von nukleosid analogen
DE60306622D1 (de) Verfahren zur herstellung von ascorbinsäure
Arava et al. A novel asymmetric synthesis of cinacalcet hydrochloride
JP2015083600A (ja) Ｎ−ビニルアミドから副生成物を除去する方法
ES8105315A1 (es) Un procedimiento para la preparacion de 5'-deoxi-5-fluo- rouridina
DE602005013382D1 (de) Feste formen des magnesiumsalzes von (s)-omeprazol und verfahren zu deren herstellung
ATE279414T1 (de) Verfahren zur herstellung von reinem triethylendiamin (teda)
Zhang et al. Dramatic solvent effect in the one-pot synthesis of substituted ureas directly from primary alcohols using the combined reagent of iodobenzene dichloride and sodium azide in ethyl acetate
EP1331215A4 (en) METHOD FOR SEPARATING REACTION PRODUCTS FROM CATALYSTS
CN109053528B (zh) 一种左乙拉西坦的合成工艺
ATE495166T1 (de) Verbessertes verfahren zur zubereitung von rabeprazol-natrium
WO2007092705A3 (en) Process for preparing gemcitabine and associated intermediates
Yamanaka et al. An efficient synthesis of the orally-active GpIIb/IIIa antagonist FR184764
Gautier et al. The iodosulfonamidation of peracetylated glycals revisited: access to 1, 2-di-nitrogenated sugars
JP2005509011A5 (forum.php)
CN104557934B (zh) 一种槐果碱的合成方法
UA83663C2 (ru) Непрерывный способ получения капролактама
ATE403658T1 (de) Verfahren zur herstellung einer lösung von reinem triethylendiamin (teda)
Balgotra et al. Direct C–N bond cleavage of N-vinyl or N-allyl arylamines: a metal-free strategy for N-devinylation and N-deallylation
EP3507274B1 (de) Verfahren zur herstellung chiraler aminonitrile
RU2794748C1 (ru) Синтез (1r,2s,5s)-n-[(1s)-1-циано-2-[(3s)-2-оксопирролидин-3-ил]этил]-3-[(2s)-3,3-диметил-2-[(2,2,2-трифторацетил)амино]бутаноил]-6,6-диметил-3-азабицикло[3.1.0]гексан-2-карбоксамида
RU2794750C1 (ru) Способ получения (1r,2s,5s)-n-[(1s)-1-циано-2-[(3s)-2-оксопирролидин-3-ил]этил]-3-[(2s)-3,3-диметил-2-[(2,2,2-трифторацетил)амино]бутаноил]-6,6-диметил-3-азабицикло[3.1.0]гексан-2-карбоксамида

Legal Events

Date Code Title Description
8364 No opposition during term of opposition