ATE495166T1 - Verbessertes verfahren zur zubereitung von rabeprazol-natrium - Google Patents
Verbessertes verfahren zur zubereitung von rabeprazol-natriumInfo
- Publication number
- ATE495166T1 ATE495166T1 AT06766260T AT06766260T ATE495166T1 AT E495166 T1 ATE495166 T1 AT E495166T1 AT 06766260 T AT06766260 T AT 06766260T AT 06766260 T AT06766260 T AT 06766260T AT E495166 T1 ATE495166 T1 AT E495166T1
- Authority
- AT
- Austria
- Prior art keywords
- addition
- solution
- improved method
- rabeprazole sodium
- rabeprazole
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- ZGDLVKWIZHHWIR-UHFFFAOYSA-N 4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]morpholine Chemical compound O1C(C)(C)C(C)(C)OB1C1=CC=C(N2CCOCC2)N=C1 ZGDLVKWIZHHWIR-UHFFFAOYSA-N 0.000 title abstract 2
- 229960001778 rabeprazole sodium Drugs 0.000 title abstract 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 238000013019 agitation Methods 0.000 abstract 1
- 239000012296 anti-solvent Substances 0.000 abstract 1
- 238000004821 distillation Methods 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 229960004157 rabeprazole Drugs 0.000 abstract 1
- YREYEVIYCVEVJK-UHFFFAOYSA-N rabeprazole Chemical compound COCCCOC1=CC=NC(CS(=O)C=2NC3=CC=CC=C3N=2)=C1C YREYEVIYCVEVJK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN370MU2005 | 2005-03-30 | ||
| PCT/IN2006/000104 WO2006120701A1 (en) | 2005-03-30 | 2006-03-16 | An improved process for the manufacture of rabeprazole sodium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE495166T1 true ATE495166T1 (de) | 2011-01-15 |
Family
ID=37022954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06766260T ATE495166T1 (de) | 2005-03-30 | 2006-03-16 | Verbessertes verfahren zur zubereitung von rabeprazol-natrium |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20080071089A1 (de) |
| EP (1) | EP1869015B1 (de) |
| JP (1) | JP2008534578A (de) |
| AT (1) | ATE495166T1 (de) |
| AU (1) | AU2006245298A1 (de) |
| BR (1) | BRPI0609622A2 (de) |
| DE (1) | DE602006019568D1 (de) |
| MX (1) | MX2007011967A (de) |
| WO (1) | WO2006120701A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2162449A4 (de) * | 2007-05-25 | 2011-07-13 | Hetero Drugs Ltd | Verbessertes verfahren für amorphes rabeprazolnatrium |
| US8247568B2 (en) | 2007-06-21 | 2012-08-21 | Matrix Laboratories Ltd | Process for the preparation of pure rabeprazole |
| WO2010004571A2 (en) * | 2008-07-07 | 2010-01-14 | Hetero Research Foundation | Process for purification of rabeprazole sodium |
| ITMI20131859A1 (it) * | 2013-11-08 | 2015-05-09 | Dipharma Francis Srl | Procedimento per la preparazione di un composto benzimidazolico in forma amorfa |
| WO2024075017A1 (en) | 2022-10-04 | 2024-04-11 | Zabirnyk Arsenii | Inhibition of aortic valve calcification |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI90544C (fi) * | 1986-11-13 | 1994-02-25 | Eisai Co Ltd | Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi |
| US5045522A (en) * | 1990-03-27 | 1991-09-03 | Phillips Petroleum Company | Absorption composition comprising zinc titanate for removal of hydrogen sulfide from fluid streams |
| ES2166269B1 (es) * | 1999-07-14 | 2003-04-01 | Sint Quimica Sa | Nuevo procedimiento de obtencion de derivados de 2-(2-piridinilmetilsulfinil)-1h-benzimidazol. |
| AU2003224781A1 (en) * | 2002-03-26 | 2003-10-13 | Dr. Reddy's Laboratories Limited | Crystalline forms of rabeprazole sodium |
-
2006
- 2006-03-16 AT AT06766260T patent/ATE495166T1/de not_active IP Right Cessation
- 2006-03-16 AU AU2006245298A patent/AU2006245298A1/en not_active Abandoned
- 2006-03-16 US US11/910,089 patent/US20080071089A1/en not_active Abandoned
- 2006-03-16 DE DE602006019568T patent/DE602006019568D1/de active Active
- 2006-03-16 WO PCT/IN2006/000104 patent/WO2006120701A1/en not_active Ceased
- 2006-03-16 MX MX2007011967A patent/MX2007011967A/es unknown
- 2006-03-16 EP EP06766260A patent/EP1869015B1/de not_active Not-in-force
- 2006-03-16 JP JP2008503687A patent/JP2008534578A/ja not_active Withdrawn
- 2006-03-16 BR BRPI0609622-0A patent/BRPI0609622A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20080071089A1 (en) | 2008-03-20 |
| BRPI0609622A2 (pt) | 2010-04-20 |
| AU2006245298A1 (en) | 2006-11-16 |
| EP1869015B1 (de) | 2011-01-12 |
| EP1869015A1 (de) | 2007-12-26 |
| DE602006019568D1 (de) | 2011-02-24 |
| MX2007011967A (es) | 2007-12-10 |
| JP2008534578A (ja) | 2008-08-28 |
| WO2006120701A1 (en) | 2006-11-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602007013242D1 (de) | Herstellung von essigsäure | |
| WO2009151256A3 (ko) | 클로피도크렐 및 그의 유도체의 제조방법 | |
| EP2123636A4 (de) | Verfahren zur herstellung eines aminoacetylpyrrolidincarbonitrilderivats | |
| UY30475A1 (es) | Procedimientos para fabricar bromuro de 3(r)-(2-hidroxi-2,2-dietien-2-ilaxetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo[2.2.2]octano. | |
| AR044510A1 (es) | Procedimiento e intermedios para preparar acidos carboxilicos de pirrolidina | |
| WO2004039992A3 (en) | Isolation of carboxylic acids from fermentation broth | |
| BR112019005294A2 (pt) | processo para preparar (±)-2-exo-(2-metilbenzilóxi)-1-metil-4-isopropil-7-oxabiciclo[2.2.1]heptano de fórmula (i) e método para prevenir ou reduzir a formação de depósitos no interior de um reator | |
| US8008532B2 (en) | Processes and methods for extraction and purification of lutein from marigold esters | |
| ATE495166T1 (de) | Verbessertes verfahren zur zubereitung von rabeprazol-natrium | |
| ATE551312T1 (de) | Verfahren zur racematspaltung von zopiclon und zwischenprodukten | |
| DE602006021411D1 (de) | Verfahren zur herstellung von optional 2-substituierten 1,6-dihydro-6-oxo-4-pyrimidincarboxylsäuren | |
| ATE437883T1 (de) | Verfahren zur trennung von zirkonium und hafnium | |
| WO2019112352A3 (ko) | 홍합접착단백질의 생산 방법 | |
| DE60327350D1 (de) | Verfahren zur herstellung von carvedilol | |
| DE602005021461D1 (de) | Verfahren zur herstellung von cabergolin | |
| ATE418541T1 (de) | Verfahren zur herstellung von carvedilol | |
| DE602006003744D1 (de) | Verfahren zur rückgewinnung von lösungsmitteln | |
| DE602005013382D1 (de) | Feste formen des magnesiumsalzes von (s)-omeprazol und verfahren zu deren herstellung | |
| WO2008026219A3 (en) | Novel polymorphs of rimonabant | |
| KR101733387B1 (ko) | 유기산 에스터의 제조방법 | |
| WO2007054784A8 (en) | An improved process for the preparation of granisetron hydrochloride | |
| DE50304869D1 (de) | Verfahren zur herstellung einer spezifischen kristallmodifikation von 2-(2-chlor-4-mesyl-benzoyl)-cyclohexan-1,3-dion | |
| EP2895460A1 (de) | Verfahren zur herstellung von atorvastatin-zwischenprodukten | |
| WO2006096709A3 (en) | Process for preparing amorphous salts | |
| CY1114079T1 (el) | Μεθοδος για την παρασκευη ibodutant (μεν15596) και σχετικων ενδιαμεσων ουσιων |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |